Peroxin-13

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Peroxin-13

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B723_LEIMU

TriTrypDb:

LmxM.34.4960

Length:

208

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10
GO:0005777	peroxisome	6	2
GO:0042579	microbody	5	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2

Expansion

Sequence features

E9B723

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B723

Function

Biological processes
Term	Name	Level	Count
GO:0008104	protein localization	4	2
GO:0009987	cellular process	1	2
GO:0016560	protein import into peroxisome matrix, docking	5	2
GO:0033036	macromolecule localization	2	2
GO:0051179	localization	1	2
GO:0051641	cellular localization	2	2
GO:0070727	cellular macromolecule localization	3	2

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	119	121	PF00675	0.690
CLV_NRD_NRD_1	124	126	PF00675	0.650
CLV_NRD_NRD_1	144	146	PF00675	0.519
CLV_PCSK_KEX2_1	140	142	PF00082	0.652
CLV_PCSK_KEX2_1	175	177	PF00082	0.418
CLV_PCSK_PC1ET2_1	140	142	PF00082	0.641
CLV_PCSK_PC1ET2_1	175	177	PF00082	0.419
CLV_PCSK_PC7_1	136	142	PF00082	0.684
CLV_PCSK_SKI1_1	125	129	PF00082	0.685
DEG_APCC_DBOX_1	124	132	PF00400	0.492
DOC_USP7_MATH_1	197	201	PF00917	0.657
DOC_WW_Pin1_4	52	57	PF00397	0.687
LIG_14-3-3_CanoR_1	176	181	PF00244	0.627
LIG_Clathr_ClatBox_1	198	202	PF01394	0.528
LIG_deltaCOP1_diTrp_1	73	78	PF00928	0.486
LIG_FHA_1	66	72	PF00498	0.580
LIG_LIR_Nem_3	73	78	PF02991	0.466
LIG_LIR_Nem_3	95	99	PF02991	0.388
LIG_PDZ_Class_2	203	208	PF00595	0.539
LIG_Pex14_2	152	156	PF04695	0.460
LIG_SH2_CRK	36	40	PF00017	0.441
LIG_SH2_PTP2	96	99	PF00017	0.411
LIG_SH2_STAT5	137	140	PF00017	0.449
LIG_SH2_STAT5	171	174	PF00017	0.334
LIG_SH2_STAT5	96	99	PF00017	0.380
LIG_SH3_3	141	147	PF00018	0.435
LIG_SUMO_SIM_par_1	195	202	PF11976	0.630
LIG_SxIP_EBH_1	124	133	PF03271	0.447
LIG_WRC_WIRS_1	153	158	PF05994	0.454
MOD_CK2_1	190	196	PF00069	0.562
MOD_GlcNHglycan	184	187	PF01048	0.648
MOD_GlcNHglycan	192	195	PF01048	0.647
MOD_GlcNHglycan	8	11	PF01048	0.603
MOD_GlcNHglycan	87	90	PF01048	0.316
MOD_GSK3_1	148	155	PF00069	0.554
MOD_GSK3_1	176	183	PF00069	0.623
MOD_GSK3_1	197	204	PF00069	0.682
MOD_NEK2_1	152	157	PF00069	0.498
MOD_NEK2_1	182	187	PF00069	0.622
MOD_NEK2_1	189	194	PF00069	0.655
MOD_NEK2_1	201	206	PF00069	0.533
MOD_NEK2_1	65	70	PF00069	0.512
MOD_NEK2_1	82	87	PF00069	0.351
MOD_NMyristoyl	1	7	PF02799	0.531
MOD_PIKK_1	76	82	PF00454	0.311
MOD_Plk_4	148	154	PF00069	0.622
MOD_ProDKin_1	52	58	PF00069	0.617
TRG_DiLeu_BaLyEn_6	156	161	PF01217	0.405
TRG_ENDOCYTIC_2	27	30	PF00928	0.517
TRG_ENDOCYTIC_2	36	39	PF00928	0.380
TRG_ENDOCYTIC_2	96	99	PF00928	0.472
TRG_ER_diArg_1	141	144	PF00400	0.554
TRG_NLS_Bipartite_1	125	144	PF00514	0.658
TRG_NLS_MonoCore_2	144	149	PF00514	0.564
TRG_NLS_MonoExtN_4	139	144	PF00514	0.567

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2X3	Leptomonas seymouri	75%	72%
A0A0S4J7P3	Bodo saltans	32%	69%
A0A0S4J8A4	Bodo saltans	31%	69%
A0A1X0P507	Trypanosomatidae	32%	73%
A0A3Q8IVL9	Leishmania donovani	94%	100%
A0A422NCL6	Trypanosoma rangeli	36%	76%
A4HNF9	Leishmania braziliensis	83%	100%
A4IC72	Leishmania infantum	93%	100%
E9AFX0	Leishmania major	91%	100%