Tail assembly chaperone

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B718_LEIMU

TriTrypDb:

LmxM.34.4900

Length:

153

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B718

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B718

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0016740	transferase activity	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	52	56	PF00656	0.689
CLV_NRD_NRD_1	44	46	PF00675	0.684
CLV_PCSK_SKI1_1	149	153	PF00082	0.649
DEG_SPOP_SBC_1	72	76	PF00917	0.773
DOC_PP2B_LxvP_1	92	95	PF13499	0.511
LIG_14-3-3_CanoR_1	3	11	PF00244	0.654
LIG_14-3-3_CterR_2	149	153	PF00244	0.560
LIG_BIR_III_4	55	59	PF00653	0.685
LIG_Clathr_ClatBox_1	120	124	PF01394	0.447
LIG_deltaCOP1_diTrp_1	143	148	PF00928	0.644
LIG_deltaCOP1_diTrp_1	99	107	PF00928	0.526
LIG_FHA_1	89	95	PF00498	0.444
LIG_FHA_2	50	56	PF00498	0.685
LIG_LIR_Gen_1	99	107	PF02991	0.466
LIG_LIR_Nem_3	130	136	PF02991	0.534
LIG_LIR_Nem_3	143	147	PF02991	0.470
LIG_LIR_Nem_3	99	103	PF02991	0.465
LIG_PDZ_Class_2	148	153	PF00595	0.463
LIG_Pex14_1	144	148	PF04695	0.485
LIG_SH2_STAT5	119	122	PF00017	0.514
LIG_SH2_STAT5	147	150	PF00017	0.635
LIG_SUMO_SIM_par_1	118	126	PF11976	0.396
LIG_TRAF2_1	122	125	PF00917	0.481
MOD_CK1_1	39	45	PF00069	0.520
MOD_GlcNHglycan	41	44	PF01048	0.558
MOD_GlcNHglycan	75	78	PF01048	0.609
MOD_PKA_2	2	8	PF00069	0.682
MOD_PKA_2	36	42	PF00069	0.528
TRG_ER_diArg_1	33	36	PF00400	0.643

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I444	Leptomonas seymouri	60%	98%
A0A1X0P5P2	Trypanosomatidae	25%	100%
A0A3S5H809	Leishmania donovani	90%	100%
A4HNF4	Leishmania braziliensis	79%	100%
A4IC26	Leishmania infantum	90%	100%
E9AFW5	Leishmania major	91%	100%