LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9B706_LEIMU
TriTrypDb:
LmxM.34.4780
Length:
151

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9B706
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B706

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 33 35 PF00675 0.488
CLV_PCSK_KEX2_1 33 35 PF00082 0.488
CLV_PCSK_SKI1_1 127 131 PF00082 0.410
DEG_Nend_UBRbox_2 1 3 PF02207 0.485
DEG_SPOP_SBC_1 112 116 PF00917 0.404
DEG_SPOP_SBC_1 63 67 PF00917 0.496
DOC_PP1_RVXF_1 125 132 PF00149 0.416
DOC_USP7_MATH_1 62 66 PF00917 0.497
DOC_USP7_MATH_1 96 100 PF00917 0.444
DOC_WW_Pin1_4 39 44 PF00397 0.471
DOC_WW_Pin1_4 87 92 PF00397 0.475
LIG_FHA_1 113 119 PF00498 0.444
LIG_FHA_1 130 136 PF00498 0.533
LIG_FHA_1 64 70 PF00498 0.534
LIG_FHA_1 8 14 PF00498 0.460
LIG_FHA_1 93 99 PF00498 0.458
LIG_LIR_Apic_2 87 91 PF02991 0.438
LIG_LIR_Gen_1 94 105 PF02991 0.549
LIG_LIR_Nem_3 94 100 PF02991 0.521
LIG_SH2_CRK 121 125 PF00017 0.426
LIG_SH2_STAP1 121 125 PF00017 0.426
LIG_TRAF2_1 143 146 PF00917 0.471
LIG_WRC_WIRS_1 51 56 PF05994 0.542
MOD_CK1_1 39 45 PF00069 0.533
MOD_CK1_1 47 53 PF00069 0.531
MOD_CK1_1 65 71 PF00069 0.436
MOD_CK1_1 87 93 PF00069 0.501
MOD_CK2_1 140 146 PF00069 0.463
MOD_CK2_1 58 64 PF00069 0.561
MOD_GlcNHglycan 10 13 PF01048 0.459
MOD_GlcNHglycan 121 124 PF01048 0.607
MOD_GlcNHglycan 142 145 PF01048 0.661
MOD_GlcNHglycan 60 63 PF01048 0.594
MOD_GSK3_1 42 49 PF00069 0.554
MOD_GSK3_1 58 65 PF00069 0.509
MOD_GSK3_1 80 87 PF00069 0.428
MOD_GSK3_1 92 99 PF00069 0.453
MOD_NEK2_1 119 124 PF00069 0.516
MOD_NEK2_1 130 135 PF00069 0.544
MOD_NEK2_1 16 21 PF00069 0.458
MOD_NEK2_1 44 49 PF00069 0.535
MOD_NEK2_1 92 97 PF00069 0.482
MOD_Plk_4 47 53 PF00069 0.548
MOD_ProDKin_1 39 45 PF00069 0.470
MOD_ProDKin_1 87 93 PF00069 0.466
TRG_DiLeu_BaLyEn_6 11 16 PF01217 0.461
TRG_DiLeu_BaLyEn_6 88 93 PF01217 0.382
TRG_ENDOCYTIC_2 121 124 PF00928 0.486
TRG_ER_diArg_1 32 34 PF00400 0.488

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7X9Z1 Leishmania donovani 71% 93%
A4HNE2 Leishmania braziliensis 47% 100%
A4IC15 Leishmania infantum 71% 93%
E9AFV3 Leishmania major 76% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS