Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B704_LEIMU

TriTrypDb:

LmxM.34.4760

Length:

148


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0016020	membrane	2	7
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	7

E9B704

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B704


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	50	52	PF00675	0.409
CLV_PCSK_KEX2_1	50	52	PF00082	0.408
DEG_Nend_UBRbox_2	1	3	PF02207	0.428
DOC_CYCLIN_RxL_1	111	125	PF00134	0.532
DOC_MAPK_JIP1_4	117	123	PF00069	0.548
DOC_MAPK_MEF2A_6	75	82	PF00069	0.349
LIG_14-3-3_CanoR_1	108	114	PF00244	0.614
LIG_FHA_1	133	139	PF00498	0.373
LIG_FHA_2	124	130	PF00498	0.531
LIG_LIR_Gen_1	12	22	PF02991	0.336
LIG_LIR_LC3C_4	76	79	PF02991	0.292
LIG_LIR_Nem_3	57	62	PF02991	0.644
LIG_LYPXL_yS_3	59	62	PF13949	0.612
LIG_PDZ_Class_2	143	148	PF00595	0.418
LIG_PTB_Apo_2	3	10	PF02174	0.472
LIG_PTB_Phospho_1	3	9	PF10480	0.472
LIG_SH2_NCK_1	128	132	PF00017	0.289
LIG_SH2_STAP1	128	132	PF00017	0.289
LIG_SH2_STAT3	92	95	PF00017	0.435
LIG_SH2_STAT5	15	18	PF00017	0.420
LIG_SH2_STAT5	42	45	PF00017	0.595
LIG_SUMO_SIM_anti_2	76	81	PF11976	0.335
LIG_SUMO_SIM_par_1	76	81	PF11976	0.449
LIG_TYR_ITSM	55	62	PF00017	0.621
MOD_CK1_1	65	71	PF00069	0.335
MOD_CK2_1	123	129	PF00069	0.531
MOD_GlcNHglycan	18	21	PF01048	0.389
MOD_GlcNHglycan	64	67	PF01048	0.376
MOD_GlcNHglycan	95	98	PF01048	0.335
MOD_GSK3_1	65	72	PF00069	0.341
MOD_N-GLC_1	86	91	PF02516	0.590
MOD_NEK2_1	69	74	PF00069	0.347
MOD_Plk_1	86	92	PF00069	0.393
MOD_Plk_4	4	10	PF00069	0.406
MOD_Plk_4	69	75	PF00069	0.310
MOD_Plk_4	78	84	PF00069	0.368
MOD_Plk_4	87	93	PF00069	0.347
TRG_ENDOCYTIC_2	15	18	PF00928	0.363
TRG_ENDOCYTIC_2	59	62	PF00928	0.629
TRG_ER_diArg_1	49	51	PF00400	0.614
TRG_ER_diLys_1	144	148	PF00400	0.436


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I454	Leptomonas seymouri	58%	100%
A0A0S4J9A3	Bodo saltans	36%	97%
A0A1X0P5Z3	Trypanosomatidae	45%	98%
A0A3S7XA03	Leishmania donovani	93%	100%
A0A422P158	Trypanosoma rangeli	42%	100%
A4HNE0	Leishmania braziliensis	80%	100%
A4IC13	Leishmania infantum	93%	100%
C9ZYI9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	97%
Q9N6L8	Leishmania major	92%	100%