LeishMANIAdb
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WXG100 family type VII secretion target

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
WXG100 family type VII secretion target
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9B6Z7_LEIMU
TriTrypDb:
LmxM.34.4680
Length:
97

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6Z7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6Z7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 77 81 PF00082 0.495
CLV_Separin_Metazoa 52 56 PF03568 0.361
DEG_APCC_DBOX_1 71 79 PF00400 0.672
DEG_SPOP_SBC_1 7 11 PF00917 0.478
DOC_USP7_MATH_1 28 32 PF00917 0.503
LIG_14-3-3_CanoR_1 27 33 PF00244 0.379
LIG_14-3-3_CanoR_1 77 82 PF00244 0.394
LIG_BIR_II_1 1 5 PF00653 0.639
LIG_FHA_1 24 30 PF00498 0.603
LIG_FHA_1 54 60 PF00498 0.508
LIG_FHA_1 9 15 PF00498 0.520
LIG_FHA_2 11 17 PF00498 0.457
LIG_FHA_2 85 91 PF00498 0.449
LIG_SUMO_SIM_anti_2 18 23 PF11976 0.519
LIG_WRC_WIRS_1 78 83 PF05994 0.394
MOD_CK1_1 10 16 PF00069 0.489
MOD_CK2_1 28 34 PF00069 0.379
MOD_GSK3_1 6 13 PF00069 0.517
MOD_N-GLC_1 23 28 PF02516 0.594
MOD_NEK2_1 53 58 PF00069 0.497
MOD_NEK2_2 28 33 PF00069 0.379
MOD_PIKK_1 8 14 PF00454 0.459
MOD_Plk_1 17 23 PF00069 0.665
MOD_Plk_1 41 47 PF00069 0.516
MOD_Plk_4 17 23 PF00069 0.621
MOD_Plk_4 77 83 PF00069 0.396
TRG_ENDOCYTIC_2 51 54 PF00928 0.575
TRG_Pf-PMV_PEXEL_1 93 97 PF00026 0.527

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IGP3 Leishmania donovani 72% 97%
A4IC07 Leishmania infantum 71% 98%
E9AFU5 Leishmania major 69% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS