Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B6V1_LEIMU

TriTrypDb:

LmxM.34.4210

Length:

746

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6V1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6V1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	12	16	PF00656	0.746
CLV_C14_Caspase3-7	198	202	PF00656	0.777
CLV_C14_Caspase3-7	428	432	PF00656	0.657
CLV_C14_Caspase3-7	583	587	PF00656	0.652
CLV_C14_Caspase3-7	597	601	PF00656	0.478
CLV_NRD_NRD_1	238	240	PF00675	0.825
CLV_NRD_NRD_1	282	284	PF00675	0.688
CLV_NRD_NRD_1	43	45	PF00675	0.527
CLV_NRD_NRD_1	517	519	PF00675	0.770
CLV_NRD_NRD_1	657	659	PF00675	0.819
CLV_NRD_NRD_1	87	89	PF00675	0.814
CLV_PCSK_KEX2_1	204	206	PF00082	0.707
CLV_PCSK_KEX2_1	219	221	PF00082	0.672
CLV_PCSK_KEX2_1	238	240	PF00082	0.555
CLV_PCSK_KEX2_1	282	284	PF00082	0.688
CLV_PCSK_KEX2_1	657	659	PF00082	0.819
CLV_PCSK_PC1ET2_1	204	206	PF00082	0.707
CLV_PCSK_PC1ET2_1	219	221	PF00082	0.672
CLV_PCSK_SKI1_1	140	144	PF00082	0.775
CLV_PCSK_SKI1_1	163	167	PF00082	0.557
CLV_PCSK_SKI1_1	219	223	PF00082	0.735
CLV_PCSK_SKI1_1	493	497	PF00082	0.561
CLV_PCSK_SKI1_1	518	522	PF00082	0.673
CLV_PCSK_SKI1_1	527	531	PF00082	0.796
CLV_PCSK_SKI1_1	638	642	PF00082	0.791
CLV_PCSK_SKI1_1	735	739	PF00082	0.679
DEG_APCC_DBOX_1	517	525	PF00400	0.760
DEG_SPOP_SBC_1	305	309	PF00917	0.781
DEG_SPOP_SBC_1	329	333	PF00917	0.556
DEG_SPOP_SBC_1	565	569	PF00917	0.780
DOC_CKS1_1	1	6	PF01111	0.762
DOC_CKS1_1	459	464	PF01111	0.721
DOC_CYCLIN_yCln2_LP_2	361	367	PF00134	0.536
DOC_CYCLIN_yCln2_LP_2	87	93	PF00134	0.554
DOC_MAPK_gen_1	355	363	PF00069	0.535
DOC_MAPK_gen_1	409	416	PF00069	0.671
DOC_MAPK_MEF2A_6	253	260	PF00069	0.547
DOC_MAPK_MEF2A_6	608	617	PF00069	0.759
DOC_PP1_RVXF_1	588	594	PF00149	0.516
DOC_PP2B_LxvP_1	361	364	PF13499	0.531
DOC_PP2B_LxvP_1	513	516	PF13499	0.538
DOC_PP2B_LxvP_1	669	672	PF13499	0.799
DOC_USP7_MATH_1	105	109	PF00917	0.559
DOC_USP7_MATH_1	131	135	PF00917	0.758
DOC_USP7_MATH_1	142	146	PF00917	0.692
DOC_USP7_MATH_1	158	162	PF00917	0.549
DOC_USP7_MATH_1	176	180	PF00917	0.553
DOC_USP7_MATH_1	192	196	PF00917	0.643
DOC_USP7_MATH_1	214	218	PF00917	0.557
DOC_USP7_MATH_1	245	249	PF00917	0.751
DOC_USP7_MATH_1	251	255	PF00917	0.652
DOC_USP7_MATH_1	289	293	PF00917	0.604
DOC_USP7_MATH_1	305	309	PF00917	0.746
DOC_USP7_MATH_1	328	332	PF00917	0.643
DOC_USP7_MATH_1	418	422	PF00917	0.803
DOC_USP7_MATH_1	43	47	PF00917	0.762
DOC_USP7_MATH_1	433	437	PF00917	0.580
DOC_USP7_MATH_1	438	442	PF00917	0.501
DOC_USP7_MATH_1	460	464	PF00917	0.782
DOC_USP7_MATH_1	565	569	PF00917	0.566
DOC_USP7_MATH_1	601	605	PF00917	0.478
DOC_USP7_MATH_1	652	656	PF00917	0.699
DOC_USP7_MATH_1	692	696	PF00917	0.642
DOC_USP7_MATH_1	739	743	PF00917	0.551
DOC_USP7_MATH_2	328	334	PF00917	0.551
DOC_USP7_UBL2_3	558	562	PF12436	0.669
DOC_WW_Pin1_4	179	184	PF00397	0.562
DOC_WW_Pin1_4	228	233	PF00397	0.586
DOC_WW_Pin1_4	293	298	PF00397	0.699
DOC_WW_Pin1_4	301	306	PF00397	0.687
DOC_WW_Pin1_4	338	343	PF00397	0.809
DOC_WW_Pin1_4	371	376	PF00397	0.786
DOC_WW_Pin1_4	39	44	PF00397	0.569
DOC_WW_Pin1_4	458	463	PF00397	0.776
DOC_WW_Pin1_4	475	480	PF00397	0.526
DOC_WW_Pin1_4	549	554	PF00397	0.647
DOC_WW_Pin1_4	662	667	PF00397	0.813
DOC_WW_Pin1_4	679	684	PF00397	0.540
DOC_WW_Pin1_4	688	693	PF00397	0.646
DOC_WW_Pin1_4	69	74	PF00397	0.524
DOC_WW_Pin1_4	702	707	PF00397	0.551
DOC_WW_Pin1_4	713	718	PF00397	0.567
LIG_14-3-3_CanoR_1	323	328	PF00244	0.695
LIG_14-3-3_CanoR_1	355	364	PF00244	0.772
LIG_14-3-3_CanoR_1	36	40	PF00244	0.588
LIG_14-3-3_CanoR_1	411	415	PF00244	0.799
LIG_14-3-3_CanoR_1	44	48	PF00244	0.730
LIG_14-3-3_CanoR_1	449	458	PF00244	0.785
LIG_14-3-3_CanoR_1	473	479	PF00244	0.789
LIG_14-3-3_CanoR_1	53	58	PF00244	0.607
LIG_14-3-3_CanoR_1	537	543	PF00244	0.578
LIG_14-3-3_CanoR_1	628	632	PF00244	0.693
LIG_14-3-3_CanoR_1	711	718	PF00244	0.667
LIG_14-3-3_CanoR_1	80	87	PF00244	0.676
LIG_Actin_WH2_2	20	38	PF00022	0.502
LIG_Actin_WH2_2	624	640	PF00022	0.779
LIG_APCC_ABBA_1	104	109	PF00400	0.667
LIG_BIR_II_1	1	5	PF00653	0.780
LIG_CtBP_PxDLS_1	553	557	PF00389	0.545
LIG_CtBP_PxDLS_1	666	670	PF00389	0.806
LIG_Dynein_DLC8_1	535	541	PF01221	0.568
LIG_FHA_1	1	7	PF00498	0.759
LIG_FHA_1	141	147	PF00498	0.707
LIG_FHA_1	244	250	PF00498	0.804
LIG_FHA_1	294	300	PF00498	0.747
LIG_FHA_1	459	465	PF00498	0.778
LIG_FHA_1	537	543	PF00498	0.578
LIG_FHA_1	593	599	PF00498	0.626
LIG_FHA_1	622	628	PF00498	0.774
LIG_FHA_1	69	75	PF00498	0.750
LIG_FHA_1	724	730	PF00498	0.564
LIG_FHA_1	99	105	PF00498	0.785
LIG_FHA_2	343	349	PF00498	0.804
LIG_FHA_2	36	42	PF00498	0.518
LIG_LIR_Nem_3	322	327	PF02991	0.787
LIG_Pex14_2	47	51	PF04695	0.715
LIG_PTAP_UEV_1	314	319	PF05743	0.658
LIG_SH2_NCK_1	132	136	PF00017	0.739
LIG_SH2_STAT3	59	62	PF00017	0.744
LIG_SH2_STAT5	470	473	PF00017	0.562
LIG_SH2_STAT5	592	595	PF00017	0.743
LIG_SH3_2	486	491	PF14604	0.678
LIG_SH3_3	133	139	PF00018	0.777
LIG_SH3_3	186	192	PF00018	0.669
LIG_SH3_3	255	261	PF00018	0.602
LIG_SH3_3	283	289	PF00018	0.807
LIG_SH3_3	312	318	PF00018	0.660
LIG_SH3_3	372	378	PF00018	0.785
LIG_SH3_3	432	438	PF00018	0.792
LIG_SH3_3	456	462	PF00018	0.713
LIG_SH3_3	482	488	PF00018	0.726
LIG_SH3_3	614	620	PF00018	0.766
LIG_SH3_3	628	634	PF00018	0.577
LIG_SH3_3	677	683	PF00018	0.785
LIG_SH3_3	700	706	PF00018	0.679
LIG_SH3_3	728	734	PF00018	0.663
LIG_Sin3_3	358	365	PF02671	0.531
LIG_SUMO_SIM_anti_2	552	558	PF11976	0.786
LIG_SUMO_SIM_par_1	594	600	PF11976	0.519
LIG_SUMO_SIM_par_1	665	670	PF11976	0.807
LIG_WRC_WIRS_1	603	608	PF05994	0.492
LIG_WW_3	235	239	PF00397	0.695
LIG_WW_3	670	674	PF00397	0.799
MOD_CDC14_SPxK_1	341	344	PF00782	0.803
MOD_CDC14_SPxK_1	346	349	PF00782	0.727
MOD_CDC14_SPxK_1	42	45	PF00782	0.524
MOD_CDK_SPK_2	228	233	PF00069	0.573
MOD_CDK_SPK_2	39	44	PF00069	0.762
MOD_CDK_SPxK_1	338	344	PF00069	0.810
MOD_CDK_SPxK_1	39	45	PF00069	0.523
MOD_CDK_SPxK_1	667	673	PF00069	0.804
MOD_CDK_SPxxK_3	306	313	PF00069	0.684
MOD_CK1_1	108	114	PF00069	0.655
MOD_CK1_1	134	140	PF00069	0.536
MOD_CK1_1	179	185	PF00069	0.597
MOD_CK1_1	195	201	PF00069	0.770
MOD_CK1_1	2	8	PF00069	0.779
MOD_CK1_1	227	233	PF00069	0.687
MOD_CK1_1	243	249	PF00069	0.643
MOD_CK1_1	304	310	PF00069	0.751
MOD_CK1_1	316	322	PF00069	0.654
MOD_CK1_1	331	337	PF00069	0.595
MOD_CK1_1	356	362	PF00069	0.775
MOD_CK1_1	374	380	PF00069	0.531
MOD_CK1_1	383	389	PF00069	0.670
MOD_CK1_1	397	403	PF00069	0.762
MOD_CK1_1	441	447	PF00069	0.686
MOD_CK1_1	448	454	PF00069	0.637
MOD_CK1_1	475	481	PF00069	0.597
MOD_CK1_1	570	576	PF00069	0.768
MOD_CK1_1	621	627	PF00069	0.770
MOD_CK1_1	660	666	PF00069	0.813
MOD_CK1_1	688	694	PF00069	0.626
MOD_CK1_1	713	719	PF00069	0.613
MOD_CK1_1	72	78	PF00069	0.543
MOD_CK1_1	79	85	PF00069	0.770
MOD_CK1_1	9	15	PF00069	0.667
MOD_CK2_1	174	180	PF00069	0.810
MOD_CK2_1	2	8	PF00069	0.648
MOD_CK2_1	220	226	PF00069	0.566
MOD_CK2_1	342	348	PF00069	0.800
MOD_CK2_1	60	66	PF00069	0.616
MOD_GlcNHglycan	118	121	PF01048	0.797
MOD_GlcNHglycan	133	136	PF01048	0.594
MOD_GlcNHglycan	176	179	PF01048	0.808
MOD_GlcNHglycan	192	195	PF01048	0.654
MOD_GlcNHglycan	201	204	PF01048	0.534
MOD_GlcNHglycan	222	225	PF01048	0.601
MOD_GlcNHglycan	242	245	PF01048	0.735
MOD_GlcNHglycan	253	256	PF01048	0.603
MOD_GlcNHglycan	291	294	PF01048	0.545
MOD_GlcNHglycan	315	318	PF01048	0.785
MOD_GlcNHglycan	358	361	PF01048	0.751
MOD_GlcNHglycan	395	399	PF01048	0.803
MOD_GlcNHglycan	479	482	PF01048	0.581
MOD_GlcNHglycan	579	582	PF01048	0.723
MOD_GlcNHglycan	624	627	PF01048	0.773
MOD_GlcNHglycan	662	665	PF01048	0.816
MOD_GlcNHglycan	687	690	PF01048	0.647
MOD_GlcNHglycan	698	701	PF01048	0.754
MOD_GlcNHglycan	741	744	PF01048	0.537
MOD_GSK3_1	130	137	PF00069	0.574
MOD_GSK3_1	166	173	PF00069	0.828
MOD_GSK3_1	195	202	PF00069	0.750
MOD_GSK3_1	2	9	PF00069	0.758
MOD_GSK3_1	220	227	PF00069	0.686
MOD_GSK3_1	289	296	PF00069	0.666
MOD_GSK3_1	301	308	PF00069	0.685
MOD_GSK3_1	309	316	PF00069	0.635
MOD_GSK3_1	319	326	PF00069	0.562
MOD_GSK3_1	338	345	PF00069	0.623
MOD_GSK3_1	35	42	PF00069	0.709
MOD_GSK3_1	379	386	PF00069	0.768
MOD_GSK3_1	441	448	PF00069	0.775
MOD_GSK3_1	471	478	PF00069	0.732
MOD_GSK3_1	566	573	PF00069	0.764
MOD_GSK3_1	618	625	PF00069	0.769
MOD_GSK3_1	653	660	PF00069	0.682
MOD_GSK3_1	675	682	PF00069	0.787
MOD_GSK3_1	68	75	PF00069	0.763
MOD_GSK3_1	684	691	PF00069	0.653
MOD_GSK3_1	692	699	PF00069	0.533
MOD_GSK3_1	719	726	PF00069	0.558
MOD_N-GLC_1	405	410	PF02516	0.755
MOD_N-GLC_1	449	454	PF02516	0.677
MOD_N-GLC_1	577	582	PF02516	0.567
MOD_N-GLC_1	660	665	PF02516	0.639
MOD_N-GLC_1	68	73	PF02516	0.755
MOD_N-GLC_1	719	724	PF02516	0.555
MOD_NEK2_1	149	154	PF00069	0.567
MOD_NEK2_1	166	171	PF00069	0.764
MOD_NEK2_1	23	28	PF00069	0.505
MOD_NEK2_1	35	40	PF00069	0.487
MOD_NEK2_1	577	582	PF00069	0.560
MOD_NEK2_1	68	73	PF00069	0.515
MOD_NEK2_1	685	690	PF00069	0.614
MOD_NEK2_2	538	543	PF00069	0.579
MOD_PIKK_1	108	114	PF00454	0.677
MOD_PIKK_1	170	176	PF00454	0.820
MOD_PIKK_1	386	392	PF00454	0.564
MOD_PIKK_1	452	458	PF00454	0.692
MOD_PIKK_1	503	509	PF00454	0.556
MOD_PIKK_1	536	542	PF00454	0.607
MOD_PIKK_1	567	573	PF00454	0.789
MOD_PIKK_1	79	85	PF00454	0.677
MOD_PK_1	323	329	PF00069	0.697
MOD_PK_1	60	66	PF00069	0.616
MOD_PKA_1	219	225	PF00069	0.805
MOD_PKA_1	282	288	PF00069	0.679
MOD_PKA_1	657	663	PF00069	0.817
MOD_PKA_2	219	225	PF00069	0.805
MOD_PKA_2	227	233	PF00069	0.699
MOD_PKA_2	237	243	PF00069	0.556
MOD_PKA_2	282	288	PF00069	0.641
MOD_PKA_2	35	41	PF00069	0.588
MOD_PKA_2	356	362	PF00069	0.665
MOD_PKA_2	410	416	PF00069	0.800
MOD_PKA_2	43	49	PF00069	0.727
MOD_PKA_2	448	454	PF00069	0.838
MOD_PKA_2	472	478	PF00069	0.789
MOD_PKA_2	536	542	PF00069	0.575
MOD_PKA_2	618	624	PF00069	0.769
MOD_PKA_2	627	633	PF00069	0.647
MOD_PKA_2	657	663	PF00069	0.817
MOD_PKA_2	710	716	PF00069	0.678
MOD_PKA_2	79	85	PF00069	0.677
MOD_Plk_4	23	29	PF00069	0.505
MOD_Plk_4	295	301	PF00069	0.544
MOD_Plk_4	316	322	PF00069	0.551
MOD_Plk_4	572	578	PF00069	0.694
MOD_Plk_4	60	66	PF00069	0.616
MOD_Plk_4	618	624	PF00069	0.769
MOD_ProDKin_1	179	185	PF00069	0.559
MOD_ProDKin_1	228	234	PF00069	0.586
MOD_ProDKin_1	293	299	PF00069	0.697
MOD_ProDKin_1	301	307	PF00069	0.687
MOD_ProDKin_1	338	344	PF00069	0.810
MOD_ProDKin_1	371	377	PF00069	0.786
MOD_ProDKin_1	39	45	PF00069	0.571
MOD_ProDKin_1	458	464	PF00069	0.775
MOD_ProDKin_1	475	481	PF00069	0.524
MOD_ProDKin_1	549	555	PF00069	0.647
MOD_ProDKin_1	662	668	PF00069	0.812
MOD_ProDKin_1	679	685	PF00069	0.541
MOD_ProDKin_1	688	694	PF00069	0.647
MOD_ProDKin_1	69	75	PF00069	0.526
MOD_ProDKin_1	702	708	PF00069	0.556
MOD_ProDKin_1	713	719	PF00069	0.569
MOD_SUMO_rev_2	124	131	PF00179	0.527
MOD_SUMO_rev_2	728	737	PF00179	0.670
TRG_DiLeu_BaEn_2	264	270	PF01217	0.545
TRG_ER_diArg_1	237	239	PF00400	0.807
TRG_ER_diArg_1	657	659	PF00400	0.812
TRG_Pf-PMV_PEXEL_1	415	419	PF00026	0.804
TRG_Pf-PMV_PEXEL_1	518	522	PF00026	0.520

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X9X6	Leishmania donovani	75%	100%
A4IBW1	Leishmania infantum	75%	100%
E9AFP8	Leishmania major	73%	100%