Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B6V0_LEIMU

TriTrypDb:

LmxM.34.4200

Length:

714

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6V0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6V0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	194	198	PF00656	0.597
CLV_NRD_NRD_1	38	40	PF00675	0.497
CLV_NRD_NRD_1	4	6	PF00675	0.642
CLV_NRD_NRD_1	651	653	PF00675	0.421
CLV_NRD_NRD_1	679	681	PF00675	0.453
CLV_PCSK_KEX2_1	38	40	PF00082	0.495
CLV_PCSK_KEX2_1	4	6	PF00082	0.642
CLV_PCSK_KEX2_1	679	681	PF00082	0.453
CLV_PCSK_SKI1_1	113	117	PF00082	0.497
CLV_PCSK_SKI1_1	18	22	PF00082	0.495
CLV_PCSK_SKI1_1	255	259	PF00082	0.542
CLV_PCSK_SKI1_1	312	316	PF00082	0.544
CLV_PCSK_SKI1_1	329	333	PF00082	0.493
CLV_PCSK_SKI1_1	366	370	PF00082	0.532
CLV_PCSK_SKI1_1	38	42	PF00082	0.555
CLV_PCSK_SKI1_1	462	466	PF00082	0.619
CLV_PCSK_SKI1_1	468	472	PF00082	0.565
CLV_PCSK_SKI1_1	570	574	PF00082	0.528
DEG_APCC_DBOX_1	311	319	PF00400	0.541
DEG_Nend_UBRbox_3	1	3	PF02207	0.646
DEG_SCF_FBW7_1	494	501	PF00400	0.668
DEG_SCF_FBW7_2	378	385	PF00400	0.521
DEG_SCF_FBW7_2	405	412	PF00400	0.637
DOC_CKS1_1	404	409	PF01111	0.641
DOC_MAPK_MEF2A_6	146	154	PF00069	0.434
DOC_PP1_RVXF_1	310	317	PF00149	0.455
DOC_PP2B_LxvP_1	603	606	PF13499	0.674
DOC_PP4_FxxP_1	404	407	PF00568	0.646
DOC_USP7_MATH_1	482	486	PF00917	0.633
DOC_USP7_MATH_1	498	502	PF00917	0.752
DOC_USP7_MATH_1	551	555	PF00917	0.488
DOC_USP7_MATH_1	575	579	PF00917	0.491
DOC_USP7_MATH_1	588	592	PF00917	0.502
DOC_USP7_MATH_1	618	622	PF00917	0.554
DOC_USP7_MATH_2	607	613	PF00917	0.548
DOC_WW_Pin1_4	378	383	PF00397	0.609
DOC_WW_Pin1_4	403	408	PF00397	0.648
DOC_WW_Pin1_4	421	426	PF00397	0.527
DOC_WW_Pin1_4	492	497	PF00397	0.822
DOC_WW_Pin1_4	570	575	PF00397	0.566
LIG_14-3-3_CanoR_1	281	286	PF00244	0.569
LIG_14-3-3_CanoR_1	462	471	PF00244	0.615
LIG_14-3-3_CanoR_1	530	534	PF00244	0.626
LIG_BRCT_BRCA1_1	476	480	PF00533	0.484
LIG_Clathr_ClatBox_1	315	319	PF01394	0.567
LIG_EH1_1	697	705	PF00400	0.451
LIG_FHA_1	115	121	PF00498	0.521
LIG_FHA_1	309	315	PF00498	0.513
LIG_FHA_1	571	577	PF00498	0.637
LIG_FHA_1	615	621	PF00498	0.559
LIG_FHA_1	641	647	PF00498	0.453
LIG_FHA_2	231	237	PF00498	0.558
LIG_FHA_2	379	385	PF00498	0.536
LIG_FHA_2	411	417	PF00498	0.555
LIG_FHA_2	497	503	PF00498	0.675
LIG_LIR_Gen_1	19	28	PF02991	0.436
LIG_LIR_Gen_1	335	344	PF02991	0.596
LIG_LIR_Gen_1	42	49	PF02991	0.492
LIG_LIR_Gen_1	474	484	PF02991	0.581
LIG_LIR_Gen_1	512	521	PF02991	0.609
LIG_LIR_Gen_1	557	565	PF02991	0.453
LIG_LIR_Gen_1	623	633	PF02991	0.420
LIG_LIR_Gen_1	686	695	PF02991	0.418
LIG_LIR_LC3C_4	216	221	PF02991	0.452
LIG_LIR_Nem_3	19	24	PF02991	0.549
LIG_LIR_Nem_3	335	341	PF02991	0.596
LIG_LIR_Nem_3	342	348	PF02991	0.553
LIG_LIR_Nem_3	42	47	PF02991	0.494
LIG_LIR_Nem_3	474	479	PF02991	0.570
LIG_LIR_Nem_3	512	518	PF02991	0.736
LIG_LIR_Nem_3	557	562	PF02991	0.530
LIG_LIR_Nem_3	623	629	PF02991	0.592
LIG_LIR_Nem_3	686	690	PF02991	0.424
LIG_MLH1_MIPbox_1	476	480	PF16413	0.484
LIG_Pex14_1	172	176	PF04695	0.515
LIG_Pex14_2	208	212	PF04695	0.578
LIG_Pex14_2	476	480	PF04695	0.572
LIG_SH2_SRC	626	629	PF00017	0.414
LIG_SH2_STAP1	626	630	PF00017	0.419
LIG_SH2_STAT5	111	114	PF00017	0.469
LIG_SH2_STAT5	176	179	PF00017	0.534
LIG_SH2_STAT5	517	520	PF00017	0.761
LIG_SH2_STAT5	628	631	PF00017	0.648
LIG_SH3_3	117	123	PF00018	0.578
LIG_SH3_3	163	169	PF00018	0.556
LIG_SH3_3	221	227	PF00018	0.512
LIG_SH3_3	263	269	PF00018	0.641
LIG_SH3_3	488	494	PF00018	0.565
LIG_SH3_3	592	598	PF00018	0.474
LIG_SUMO_SIM_anti_2	544	549	PF11976	0.550
LIG_SUMO_SIM_par_1	665	672	PF11976	0.425
LIG_SUMO_SIM_par_1	702	709	PF11976	0.464
LIG_TRAF2_1	207	210	PF00917	0.572
LIG_TRAF2_1	351	354	PF00917	0.530
LIG_TRAF2_1	382	385	PF00917	0.516
LIG_TRAF2_1	51	54	PF00917	0.487
LIG_UBA3_1	315	321	PF00899	0.572
LIG_WRC_WIRS_1	136	141	PF05994	0.579
LIG_WRC_WIRS_1	476	481	PF05994	0.484
LIG_WRC_WIRS_1	684	689	PF05994	0.426
LIG_WRC_WIRS_1	85	90	PF05994	0.502
LIG_WW_1	274	277	PF00397	0.598
MOD_CK1_1	349	355	PF00069	0.616
MOD_CK1_1	424	430	PF00069	0.638
MOD_CK1_1	443	449	PF00069	0.560
MOD_CK1_1	48	54	PF00069	0.613
MOD_CK1_1	520	526	PF00069	0.591
MOD_CK1_1	578	584	PF00069	0.551
MOD_CK1_1	662	668	PF00069	0.435
MOD_CK1_1	87	93	PF00069	0.486
MOD_CK2_1	378	384	PF00069	0.555
MOD_CK2_1	410	416	PF00069	0.553
MOD_CK2_1	48	54	PF00069	0.490
MOD_CK2_1	551	557	PF00069	0.427
MOD_DYRK1A_RPxSP_1	570	574	PF00069	0.476
MOD_GlcNHglycan	140	143	PF01048	0.567
MOD_GlcNHglycan	362	365	PF01048	0.599
MOD_GlcNHglycan	432	435	PF01048	0.605
MOD_GlcNHglycan	484	487	PF01048	0.654
MOD_GlcNHglycan	526	529	PF01048	0.516
MOD_GlcNHglycan	570	573	PF01048	0.552
MOD_GlcNHglycan	586	589	PF01048	0.705
MOD_GlcNHglycan	611	614	PF01048	0.538
MOD_GlcNHglycan	622	625	PF01048	0.465
MOD_GSK3_1	255	262	PF00069	0.644
MOD_GSK3_1	349	356	PF00069	0.518
MOD_GSK3_1	367	374	PF00069	0.570
MOD_GSK3_1	389	396	PF00069	0.692
MOD_GSK3_1	424	431	PF00069	0.549
MOD_GSK3_1	492	499	PF00069	0.744
MOD_GSK3_1	516	523	PF00069	0.685
MOD_GSK3_1	524	531	PF00069	0.670
MOD_GSK3_1	564	571	PF00069	0.582
MOD_GSK3_1	584	591	PF00069	0.460
MOD_GSK3_1	614	621	PF00069	0.700
MOD_GSK3_1	84	91	PF00069	0.509
MOD_N-GLC_1	126	131	PF02516	0.555
MOD_N-GLC_1	281	286	PF02516	0.495
MOD_N-GLC_1	378	383	PF02516	0.565
MOD_N-GLC_1	474	479	PF02516	0.483
MOD_N-GLC_1	524	529	PF02516	0.519
MOD_NEK2_1	126	131	PF00069	0.478
MOD_NEK2_1	140	145	PF00069	0.469
MOD_NEK2_1	219	224	PF00069	0.444
MOD_NEK2_1	45	50	PF00069	0.537
MOD_NEK2_1	480	485	PF00069	0.599
MOD_NEK2_1	88	93	PF00069	0.422
MOD_NEK2_2	111	116	PF00069	0.394
MOD_NEK2_2	536	541	PF00069	0.583
MOD_PIKK_1	126	132	PF00454	0.501
MOD_PIKK_1	219	225	PF00454	0.525
MOD_PIKK_1	346	352	PF00454	0.608
MOD_PIKK_1	469	475	PF00454	0.730
MOD_PKA_2	529	535	PF00069	0.618
MOD_Plk_1	126	132	PF00069	0.465
MOD_Plk_1	281	287	PF00069	0.498
MOD_Plk_1	352	358	PF00069	0.511
MOD_Plk_1	45	51	PF00069	0.616
MOD_Plk_1	474	480	PF00069	0.484
MOD_Plk_1	662	668	PF00069	0.435
MOD_Plk_2-3	416	422	PF00069	0.559
MOD_Plk_4	111	117	PF00069	0.433
MOD_Plk_4	135	141	PF00069	0.580
MOD_Plk_4	281	287	PF00069	0.498
MOD_Plk_4	475	481	PF00069	0.483
MOD_Plk_4	575	581	PF00069	0.481
MOD_Plk_4	662	668	PF00069	0.435
MOD_Plk_4	669	675	PF00069	0.408
MOD_Plk_4	69	75	PF00069	0.450
MOD_ProDKin_1	378	384	PF00069	0.609
MOD_ProDKin_1	403	409	PF00069	0.644
MOD_ProDKin_1	421	427	PF00069	0.527
MOD_ProDKin_1	492	498	PF00069	0.820
MOD_ProDKin_1	570	576	PF00069	0.566
MOD_SUMO_for_1	49	52	PF00179	0.484
MOD_SUMO_rev_2	210	220	PF00179	0.475
MOD_SUMO_rev_2	289	295	PF00179	0.629
MOD_SUMO_rev_2	363	371	PF00179	0.480
MOD_SUMO_rev_2	587	596	PF00179	0.479
TRG_DiLeu_BaEn_4	184	190	PF01217	0.553
TRG_ENDOCYTIC_2	338	341	PF00928	0.594
TRG_ENDOCYTIC_2	559	562	PF00928	0.518
TRG_ENDOCYTIC_2	626	629	PF00928	0.545
TRG_ER_diArg_1	107	110	PF00400	0.396
TRG_ER_diArg_1	164	167	PF00400	0.440
TRG_ER_diArg_1	3	5	PF00400	0.652
TRG_ER_diArg_1	649	652	PF00400	0.428
TRG_ER_diArg_1	679	681	PF00400	0.453
TRG_Pf-PMV_PEXEL_1	146	151	PF00026	0.442

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4IBW0	Leishmania infantum	76%	100%
E9AFP7	Leishmania major	75%	100%