Putative elongation factor 1-alpha (Hsp70 subfamily b suppressor 1)

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hsp70 subfamily B suppressor 1

Species:

Leishmania mexicana

UniProt:

E9B6U5_LEIMU

TriTrypDb:

LmxM.34.4150

Length:

645

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9B6U5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6U5

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	1
GO:0006414	translational elongation	5	1
GO:0006518	peptide metabolic process	4	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009058	biosynthetic process	2	1
GO:0009059	macromolecule biosynthetic process	4	1
GO:0009987	cellular process	1	1
GO:0019538	protein metabolic process	3	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	1
GO:0043043	peptide biosynthetic process	5	1
GO:0043170	macromolecule metabolic process	3	1
GO:0043603	amide metabolic process	3	1
GO:0043604	amide biosynthetic process	4	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0071704	organic substance metabolic process	2	1
GO:1901564	organonitrogen compound metabolic process	3	1
GO:1901566	organonitrogen compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003676	nucleic acid binding	3	10
GO:0003746	translation elongation factor activity	4	10
GO:0003824	catalytic activity	1	11
GO:0003924	GTPase activity	7	11
GO:0005488	binding	1	11
GO:0005525	GTP binding	5	11
GO:0008135	translation factor activity, RNA binding	3	10
GO:0016462	pyrophosphatase activity	5	11
GO:0016787	hydrolase activity	2	11
GO:0016817	hydrolase activity, acting on acid anhydrides	3	11
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	11
GO:0017076	purine nucleotide binding	4	11
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	11
GO:0019001	guanyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032561	guanyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0045182	translation regulator activity	1	10
GO:0090079	translation regulator activity, nucleic acid binding	2	10
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	178	182	PF00656	0.624
CLV_C14_Caspase3-7	325	329	PF00656	0.472
CLV_C14_Caspase3-7	577	581	PF00656	0.538
CLV_MEL_PAP_1	248	254	PF00089	0.310
CLV_NRD_NRD_1	209	211	PF00675	0.664
CLV_NRD_NRD_1	286	288	PF00675	0.231
CLV_NRD_NRD_1	303	305	PF00675	0.207
CLV_PCSK_FUR_1	143	147	PF00082	0.638
CLV_PCSK_KEX2_1	138	140	PF00082	0.527
CLV_PCSK_KEX2_1	145	147	PF00082	0.610
CLV_PCSK_KEX2_1	161	163	PF00082	0.740
CLV_PCSK_KEX2_1	209	211	PF00082	0.678
CLV_PCSK_KEX2_1	285	287	PF00082	0.257
CLV_PCSK_KEX2_1	303	305	PF00082	0.194
CLV_PCSK_PC1ET2_1	138	140	PF00082	0.565
CLV_PCSK_PC1ET2_1	145	147	PF00082	0.646
CLV_PCSK_PC1ET2_1	161	163	PF00082	0.725
CLV_PCSK_SKI1_1	212	216	PF00082	0.645
CLV_PCSK_SKI1_1	287	291	PF00082	0.258
CLV_PCSK_SKI1_1	419	423	PF00082	0.341
CLV_PCSK_SKI1_1	470	474	PF00082	0.392
CLV_PCSK_SKI1_1	547	551	PF00082	0.296
CLV_PCSK_SKI1_1	623	627	PF00082	0.305
DEG_APCC_DBOX_1	450	458	PF00400	0.396
DEG_Nend_UBRbox_3	1	3	PF02207	0.572
DOC_MAPK_gen_1	143	153	PF00069	0.711
DOC_MAPK_gen_1	285	291	PF00069	0.457
DOC_PP2B_LxvP_1	104	107	PF13499	0.307
DOC_PP2B_LxvP_1	308	311	PF13499	0.458
DOC_USP7_MATH_1	168	172	PF00917	0.571
DOC_USP7_MATH_1	187	191	PF00917	0.733
DOC_USP7_MATH_1	236	240	PF00917	0.469
DOC_USP7_MATH_1	336	340	PF00917	0.472
DOC_USP7_MATH_1	440	444	PF00917	0.474
DOC_USP7_MATH_1	45	49	PF00917	0.718
DOC_USP7_MATH_1	487	491	PF00917	0.450
DOC_USP7_MATH_1	55	59	PF00917	0.673
DOC_USP7_MATH_1	555	559	PF00917	0.496
DOC_USP7_UBL2_3	269	273	PF12436	0.475
DOC_USP7_UBL2_3	489	493	PF12436	0.437
DOC_USP7_UBL2_3	578	582	PF12436	0.487
DOC_USP7_UBL2_3	588	592	PF12436	0.456
DOC_WW_Pin1_4	185	190	PF00397	0.722
DOC_WW_Pin1_4	421	426	PF00397	0.455
DOC_WW_Pin1_4	445	450	PF00397	0.441
DOC_WW_Pin1_4	48	53	PF00397	0.680
DOC_WW_Pin1_4	605	610	PF00397	0.496
DOC_WW_Pin1_4	78	83	PF00397	0.597
LIG_14-3-3_CanoR_1	162	167	PF00244	0.703
LIG_14-3-3_CanoR_1	195	201	PF00244	0.790
LIG_14-3-3_CanoR_1	451	455	PF00244	0.366
LIG_Actin_WH2_2	438	453	PF00022	0.382
LIG_BIR_III_4	309	313	PF00653	0.458
LIG_BRCT_BRCA1_1	292	296	PF00533	0.463
LIG_BRCT_BRCA1_1	535	539	PF00533	0.458
LIG_eIF4E_1	427	433	PF01652	0.472
LIG_FHA_1	195	201	PF00498	0.699
LIG_FHA_1	225	231	PF00498	0.311
LIG_FHA_1	356	362	PF00498	0.472
LIG_FHA_1	506	512	PF00498	0.364
LIG_FHA_1	548	554	PF00498	0.501
LIG_FHA_1	558	564	PF00498	0.426
LIG_FHA_1	565	571	PF00498	0.379
LIG_FHA_1	637	643	PF00498	0.561
LIG_FHA_2	111	117	PF00498	0.459
LIG_FHA_2	323	329	PF00498	0.472
LIG_FHA_2	535	541	PF00498	0.480
LIG_GBD_Chelix_1	384	392	PF00786	0.272
LIG_IBAR_NPY_1	75	77	PF08397	0.721
LIG_LIR_Gen_1	129	137	PF02991	0.508
LIG_LIR_Gen_1	271	278	PF02991	0.441
LIG_LIR_Gen_1	379	388	PF02991	0.458
LIG_LIR_Gen_1	424	435	PF02991	0.549
LIG_LIR_Gen_1	460	471	PF02991	0.391
LIG_LIR_Gen_1	558	566	PF02991	0.494
LIG_LIR_Gen_1	85	96	PF02991	0.455
LIG_LIR_Nem_3	129	135	PF02991	0.501
LIG_LIR_Nem_3	271	277	PF02991	0.441
LIG_LIR_Nem_3	379	384	PF02991	0.442
LIG_LIR_Nem_3	424	430	PF02991	0.549
LIG_LIR_Nem_3	460	466	PF02991	0.395
LIG_LIR_Nem_3	545	549	PF02991	0.446
LIG_LIR_Nem_3	558	562	PF02991	0.446
LIG_LIR_Nem_3	85	91	PF02991	0.447
LIG_NRBOX	241	247	PF00104	0.472
LIG_NRBOX	387	393	PF00104	0.455
LIG_Pex14_2	272	276	PF04695	0.441
LIG_SH2_CRK	381	385	PF00017	0.482
LIG_SH2_CRK	77	81	PF00017	0.612
LIG_SH2_NCK_1	38	42	PF00017	0.776
LIG_SH2_NCK_1	463	467	PF00017	0.488
LIG_SH2_NCK_1	77	81	PF00017	0.640
LIG_SH2_NCK_1	8	12	PF00017	0.660
LIG_SH2_SRC	38	41	PF00017	0.745
LIG_SH2_SRC	381	384	PF00017	0.488
LIG_SH2_SRC	8	11	PF00017	0.659
LIG_SH2_STAP1	274	278	PF00017	0.472
LIG_SH2_STAP1	28	32	PF00017	0.683
LIG_SH2_STAP1	38	42	PF00017	0.749
LIG_SH2_STAP1	381	385	PF00017	0.466
LIG_SH2_STAP1	43	47	PF00017	0.767
LIG_SH2_STAP1	8	12	PF00017	0.643
LIG_SH2_STAT5	383	386	PF00017	0.487
LIG_SH2_STAT5	77	80	PF00017	0.648
LIG_SH3_3	443	449	PF00018	0.525
LIG_SH3_3	493	499	PF00018	0.547
LIG_SH3_3	639	645	PF00018	0.545
LIG_SH3_3	64	70	PF00018	0.685
LIG_Sin3_3	329	336	PF02671	0.458
LIG_SUMO_SIM_anti_2	351	358	PF11976	0.473
LIG_SUMO_SIM_anti_2	429	434	PF11976	0.532
LIG_SUMO_SIM_par_1	330	335	PF11976	0.472
LIG_SUMO_SIM_par_1	351	358	PF11976	0.487
LIG_SUMO_SIM_par_1	507	513	PF11976	0.394
LIG_SUMO_SIM_par_1	571	577	PF11976	0.450
LIG_SUMO_SIM_par_1	607	613	PF11976	0.538
LIG_TYR_ITSM	459	466	PF00017	0.496
LIG_UBA3_1	214	221	PF00899	0.650
LIG_UBA3_1	353	357	PF00899	0.455
LIG_UBA3_1	432	438	PF00899	0.525
LIG_UBA3_1	575	582	PF00899	0.528
LIG_UBA3_1	94	103	PF00899	0.487
LIG_Vh1_VBS_1	561	579	PF01044	0.488
LIG_WRC_WIRS_1	543	548	PF05994	0.472
MOD_CDC14_SPxK_1	448	451	PF00782	0.414
MOD_CDK_SPxK_1	445	451	PF00069	0.434
MOD_CK1_1	190	196	PF00069	0.729
MOD_CK1_1	203	209	PF00069	0.704
MOD_CK1_1	322	328	PF00069	0.471
MOD_CK1_1	409	415	PF00069	0.521
MOD_CK1_1	48	54	PF00069	0.742
MOD_CK1_1	512	518	PF00069	0.481
MOD_CK1_1	58	64	PF00069	0.708
MOD_CK2_1	110	116	PF00069	0.520
MOD_CK2_1	177	183	PF00069	0.783
MOD_CK2_1	336	342	PF00069	0.456
MOD_CK2_1	428	434	PF00069	0.561
MOD_CK2_1	534	540	PF00069	0.480
MOD_Cter_Amidation	159	162	PF01082	0.468
MOD_DYRK1A_RPxSP_1	605	609	PF00069	0.528
MOD_GlcNHglycan	170	173	PF01048	0.556
MOD_GlcNHglycan	185	188	PF01048	0.714
MOD_GlcNHglycan	189	192	PF01048	0.675
MOD_GlcNHglycan	292	295	PF01048	0.288
MOD_GlcNHglycan	322	325	PF01048	0.258
MOD_GlcNHglycan	408	411	PF01048	0.258
MOD_GlcNHglycan	467	470	PF01048	0.389
MOD_GlcNHglycan	47	50	PF01048	0.756
MOD_GSK3_1	112	119	PF00069	0.537
MOD_GSK3_1	183	190	PF00069	0.683
MOD_GSK3_1	196	203	PF00069	0.609
MOD_GSK3_1	204	211	PF00069	0.675
MOD_GSK3_1	332	339	PF00069	0.442
MOD_GSK3_1	505	512	PF00069	0.473
MOD_GSK3_1	545	552	PF00069	0.450
MOD_GSK3_1	55	62	PF00069	0.642
MOD_GSK3_1	574	581	PF00069	0.534
MOD_N-GLC_1	414	419	PF02516	0.361
MOD_N-GLC_1	513	518	PF02516	0.474
MOD_N-GLC_1	584	589	PF02516	0.273
MOD_NEK2_1	121	126	PF00069	0.540
MOD_NEK2_1	200	205	PF00069	0.658
MOD_NEK2_1	320	325	PF00069	0.453
MOD_NEK2_1	332	337	PF00069	0.443
MOD_NEK2_1	392	397	PF00069	0.534
MOD_NEK2_1	450	455	PF00069	0.352
MOD_NEK2_1	532	537	PF00069	0.364
MOD_NEK2_1	549	554	PF00069	0.346
MOD_NEK2_1	57	62	PF00069	0.678
MOD_PIKK_1	204	210	PF00454	0.718
MOD_PIKK_1	322	328	PF00454	0.472
MOD_PIKK_1	374	380	PF00454	0.510
MOD_PIKK_1	414	420	PF00454	0.549
MOD_PIKK_1	59	65	PF00454	0.703
MOD_PKA_1	161	167	PF00069	0.771
MOD_PKA_2	121	127	PF00069	0.502
MOD_PKA_2	161	167	PF00069	0.783
MOD_PKA_2	194	200	PF00069	0.730
MOD_PKA_2	208	214	PF00069	0.626
MOD_PKA_2	250	256	PF00069	0.510
MOD_PKA_2	450	456	PF00069	0.370
MOD_PKB_1	285	293	PF00069	0.458
MOD_Plk_1	224	230	PF00069	0.324
MOD_Plk_1	428	434	PF00069	0.506
MOD_Plk_1	513	519	PF00069	0.464
MOD_Plk_2-3	177	183	PF00069	0.724
MOD_Plk_4	105	111	PF00069	0.548
MOD_Plk_4	224	230	PF00069	0.311
MOD_Plk_4	360	366	PF00069	0.538
MOD_Plk_4	428	434	PF00069	0.472
MOD_Plk_4	458	464	PF00069	0.466
MOD_Plk_4	549	555	PF00069	0.456
MOD_ProDKin_1	185	191	PF00069	0.721
MOD_ProDKin_1	421	427	PF00069	0.455
MOD_ProDKin_1	445	451	PF00069	0.434
MOD_ProDKin_1	48	54	PF00069	0.675
MOD_ProDKin_1	605	611	PF00069	0.496
MOD_ProDKin_1	78	84	PF00069	0.598
MOD_SUMO_for_1	464	467	PF00179	0.484
MOD_SUMO_rev_2	577	583	PF00179	0.528
TRG_AP2beta_CARGO_1	129	139	PF09066	0.510
TRG_DiLeu_BaEn_1	387	392	PF01217	0.458
TRG_DiLeu_BaEn_1	528	533	PF01217	0.556
TRG_ENDOCYTIC_2	274	277	PF00928	0.472
TRG_ENDOCYTIC_2	381	384	PF00928	0.454
TRG_ENDOCYTIC_2	427	430	PF00928	0.547
TRG_ENDOCYTIC_2	463	466	PF00928	0.485
TRG_ENDOCYTIC_2	77	80	PF00928	0.574
TRG_ENDOCYTIC_2	8	11	PF00928	0.554
TRG_ENDOCYTIC_2	88	91	PF00928	0.376
TRG_ER_diArg_1	285	287	PF00400	0.458
TRG_ER_diArg_1	303	305	PF00400	0.458

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5B5	Leptomonas seymouri	73%	99%
A0A0N1PAZ5	Leptomonas seymouri	32%	85%
A0A0S4IUT7	Bodo saltans	35%	100%
A0A0S4IX91	Bodo saltans	33%	96%
A0A0S4JRG2	Bodo saltans	35%	100%
A0A1X0NXE4	Trypanosomatidae	36%	100%
A0A1X0P591	Trypanosomatidae	58%	96%
A0A3Q8ICH2	Leishmania donovani	31%	85%
A0A3R7MLL0	Trypanosoma rangeli	33%	97%
A0A3S7X9T0	Leishmania donovani	93%	100%
A0A422NK97	Trypanosoma rangeli	53%	98%
A0KP35	Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)	26%	100%
A0RUM4	Cenarchaeum symbiosum (strain A)	33%	100%
A1AEU5	Escherichia coli O1:K1 / APEC	26%	100%
A1JJT0	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	25%	100%
A1RRJ3	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	37%	100%
A1RXW9	Thermofilum pendens (strain DSM 2475 / Hrk 5)	35%	100%
A2BN41	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	36%	100%
A2Q0Z0	Equus caballus	34%	100%
A3DMQ1	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	35%	100%
A4H6P3	Leishmania braziliensis	32%	100%
A4H8V4	Leishmania braziliensis	34%	100%
A4HN87	Leishmania braziliensis	82%	100%
A4HV24	Leishmania infantum	31%	85%
A4HX73	Leishmania infantum	35%	100%
A4IBV5	Leishmania infantum	93%	100%
A4SRG8	Aeromonas salmonicida (strain A449)	26%	100%
A4YCR6	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	32%	100%
A5DPE3	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	33%	100%
A7FLY2	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	26%	100%
A7MJ69	Cronobacter sakazakii (strain ATCC BAA-894)	26%	100%
A7ZQJ5	Escherichia coli O139:H28 (strain E24377A / ETEC)	26%	100%
A8A3N0	Escherichia coli O9:H4 (strain HS)	26%	100%
A8ABM5	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	37%	100%
A8ANW5	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	26%	100%
A8MAJ1	Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)	37%	100%
A9MF24	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	26%	100%
A9N2D8	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	27%	100%
A9W4X1	Methylorubrum extorquens (strain PA1)	27%	100%
B1IUS8	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	25%	100%
B1LQ72	Escherichia coli (strain SMS-3-5 / SECEC)	26%	100%
B1XCS7	Escherichia coli (strain K12 / DH10B)	26%	100%
B2TZI0	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	26%	100%
B2VG01	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	24%	100%
B4RTW4	Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)	26%	100%
B4T461	Salmonella newport (strain SL254)	26%	100%
B4TFX1	Salmonella heidelberg (strain SL476)	27%	100%
B4TTW5	Salmonella schwarzengrund (strain CVM19633)	27%	100%
B5BEY8	Salmonella paratyphi A (strain AKU_12601)	27%	100%
B5F415	Salmonella agona (strain SL483)	27%	100%
B5FGJ9	Aliivibrio fischeri (strain MJ11)	24%	100%
B5FTS9	Salmonella dublin (strain CT_02021853)	27%	100%
B5QW22	Salmonella enteritidis PT4 (strain P125109)	27%	100%
B5RDQ7	Salmonella gallinarum (strain 287/91 / NCTC 13346)	27%	100%
B5Z3B3	Escherichia coli O157:H7 (strain EC4115 / EHEC)	26%	100%
B6I6E1	Escherichia coli (strain SE11)	26%	100%
B7L0X9	Methylorubrum extorquens (strain CM4 / NCIMB 13688)	26%	100%
B7LEG9	Escherichia coli (strain 55989 / EAEC)	26%	100%
B7LXG3	Escherichia coli O8 (strain IAI1)	26%	100%
B7MKM5	Escherichia coli O45:K1 (strain S88 / ExPEC)	26%	100%
B7MZ52	Escherichia coli O81 (strain ED1a)	26%	100%
B7NT95	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	26%	100%
B7UHH0	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	26%	100%
B7VKY2	Vibrio atlanticus (strain LGP32)	27%	100%
B8D7V3	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7)	25%	100%
B8D9K1	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)	25%	100%
B9JB95	Agrobacterium radiobacter (strain K84 / ATCC BAA-868)	27%	100%
C0PXB1	Salmonella paratyphi C (strain RKS4594)	27%	100%
C4ZZQ5	Escherichia coli (strain K12 / MC4100 / BW2952)	26%	100%
C9ZYQ4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	100%
D0A1M7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
D0A1M9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
D0A7C5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	92%
E9AFP2	Leishmania major	94%	100%
E9AGP5	Leishmania infantum	35%	100%
E9AGP7	Leishmania infantum	32%	100%
E9ANQ6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9ARD0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
O13354	Candida albicans	34%	90%
O24534	Vicia faba	34%	100%
O33581	Rhizobium tropici	27%	100%
O42820	Schizophyllum commune	33%	100%
O49169	Manihot esculenta	34%	100%
O50274	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	26%	100%
O59949	Yarrowia lipolytica (strain CLIB 122 / E 150)	34%	100%
O64937	Oryza sativa subsp. japonica	35%	100%
O74718	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	97%
O74774	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	100%
P02993	Artemia salina	34%	100%
P02994	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	100%
P05303	Drosophila melanogaster	35%	100%
P05453	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	94%
P06805	Mucor circinelloides f. lusitanicus	33%	100%
P08736	Drosophila melanogaster	34%	100%
P0CN30	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	34%	100%
P0CN31	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	34%	100%
P0CT31	Dictyostelium discoideum	36%	100%
P0CT32	Dictyostelium discoideum	36%	100%
P0CT53	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
P0CT54	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
P0CT55	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
P0CY35	Candida albicans (strain SC5314 / ATCC MYA-2876)	34%	100%
P0DH99	Arabidopsis thaliana	34%	100%
P10126	Mus musculus	34%	100%
P13549	Xenopus laevis	34%	100%
P14864	Mucor circinelloides f. lusitanicus	33%	100%
P14865	Mucor circinelloides f. lusitanicus	33%	100%
P14963	Euglena gracilis	35%	100%
P15170	Homo sapiens	36%	100%
P17196	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	32%	100%
P17506	Xenopus laevis	36%	100%
P17507	Xenopus laevis	33%	100%
P17508	Xenopus laevis	34%	100%
P17745	Arabidopsis thaliana	25%	100%
P17786	Solanum lycopersicum	35%	100%
P19039	Apis mellifera	35%	100%
P23637	Ogataea pini	35%	87%
P23845	Escherichia coli (strain K12)	26%	100%
P25166	Stylonychia lemnae	34%	100%
P25698	Glycine max	34%	100%
P26751	Pyrococcus woesei	36%	100%
P27592	Onchocerca volvulus	33%	100%
P28295	Absidia glauca	33%	100%
P28604	Azospirillum brasilense	27%	100%
P29520	Bombyx mori	35%	100%
P29521	Daucus carota	35%	100%
P31018	Entamoeba histolytica	37%	100%
P32186	Puccinia graminis	33%	100%
P32769	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	100%
P34823	Daucus carota	34%	100%
P34824	Hordeum vulgare	33%	100%
P34825	Hypocrea jecorina	33%	100%
P35021	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	34%	100%
P40911	Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)	34%	100%
P41203	Desulfurococcus mucosus	34%	100%
P41745	Blastobotrys adeninivorans	35%	100%
P41752	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	100%
P43643	Nicotiana tabacum	34%	100%
P46280	Glycine max	25%	100%
P50256	Porphyra purpurea	36%	100%
P51554	Hydra vulgaris	32%	100%
P52978	Rhizobium tropici	26%	100%
P53013	Caenorhabditis elegans	33%	100%
P54959	Blastocystis hominis	35%	100%
P56893	Rhizobium meliloti (strain 1021)	27%	100%
P57498	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	25%	100%
P62629	Cricetulus griseus	34%	100%
P62630	Rattus norvegicus	34%	100%
P62631	Mus musculus	34%	100%
P62632	Rattus norvegicus	34%	100%
P68103	Bos taurus	34%	100%
P68104	Homo sapiens	34%	100%
P68105	Oryctolagus cuniculus	34%	100%
P68158	Nicotiana tabacum	26%	100%
P72339	Rhizobium sp. (strain N33)	27%	100%
P86933	Trypanosoma brucei brucei	35%	100%
P86934	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	36%	100%
P86939	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	36%	100%
P90519	Cryptosporidium parvum	35%	100%
P9WNM4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	27%	100%
P9WNM5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	27%	100%
Q00080	Plasmodium falciparum (isolate K1 / Thailand)	35%	100%
Q00251	Aureobasidium pullulans	34%	100%
Q01372	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	34%	100%
Q01520	Podospora anserina	33%	100%
Q01765	Podospora curvicolla	33%	100%
Q03033	Triticum aestivum	33%	100%
Q04634	Tetrahymena pyriformis	33%	100%
Q05639	Homo sapiens	34%	100%
Q09069	Sordaria macrospora	34%	100%
Q0T1I2	Shigella flexneri serotype 5b (strain 8401)	26%	100%
Q0TEA7	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	26%	100%
Q0WL56	Arabidopsis thaliana	34%	100%
Q149F3	Mus musculus	36%	100%
Q14HG2	Francisella tularensis subsp. tularensis (strain FSC 198)	27%	100%
Q1R7U0	Escherichia coli (strain UTI89 / UPEC)	26%	100%
Q21IS6	Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)	26%	100%
Q27139	Euplotes crassus	34%	100%
Q27140	Euplotes crassus	33%	100%
Q2HJN4	Oscheius tipulae	34%	100%
Q2HJN6	Oscheius tipulae	35%	100%
Q2HJN8	Oscheius tipulae	34%	100%
Q2HJN9	Oscheius tipulae	34%	100%
Q2KHZ2	Bos taurus	36%	94%
Q2NVM8	Sodalis glossinidius (strain morsitans)	26%	100%
Q31XB3	Shigella boydii serotype 4 (strain Sb227)	26%	100%
Q32CH9	Shigella dysenteriae serotype 1 (strain Sd197)	26%	100%
Q32PH8	Bos taurus	34%	100%
Q3YYB1	Shigella sonnei (strain Ss046)	26%	100%
Q40034	Hordeum vulgare	33%	100%
Q40450	Nicotiana sylvestris	26%	100%
Q41011	Pisum sativum	34%	100%
Q41803	Zea mays	34%	100%
Q43467	Glycine max	25%	100%
Q4QEI8	Leishmania major	34%	100%
Q4QEI9	Leishmania major	35%	100%
Q4QGW5	Leishmania major	31%	85%
Q57KJ0	Salmonella choleraesuis (strain SC-B67)	27%	100%
Q59QD6	Candida albicans (strain SC5314 / ATCC MYA-2876)	34%	100%
Q5E830	Aliivibrio fischeri (strain ATCC 700601 / ES114)	25%	100%
Q5LES3	Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow)	29%	100%
Q5NG10	Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)	27%	100%
Q5PEH2	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	27%	100%
Q5R1X2	Pan troglodytes	34%	100%
Q5R4B3	Pongo abelii	35%	100%
Q5R4R8	Pongo abelii	34%	100%
Q5R6Y0	Pongo abelii	36%	94%
Q5VTE0	Homo sapiens	34%	100%
Q64VQ9	Bacteroides fragilis (strain YCH46)	29%	100%
Q66EC7	Yersinia pseudotuberculosis serotype I (strain IP32953)	26%	100%
Q66RN5	Felis catus	34%	100%
Q69ZS7	Mus musculus	36%	95%
Q6AXM7	Rattus norvegicus	37%	95%
Q71V39	Oryctolagus cuniculus	34%	100%
Q74MI6	Nanoarchaeum equitans (strain Kin4-M)	33%	100%
Q7MPF2	Vibrio vulnificus (strain YJ016)	26%	100%
Q7NVN5	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	27%	100%
Q7UMW2	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	25%	100%
Q7YZN9	Dictyostelium discoideum	32%	100%
Q83JX8	Shigella flexneri	26%	100%
Q87DG7	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	28%	100%
Q8DE73	Vibrio vulnificus (strain CMCP6)	26%	100%
Q8FEJ1	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	26%	100%
Q8GTY0	Arabidopsis thaliana	34%	100%
Q8IYD1	Homo sapiens	35%	100%
Q8LPC4	Neopyropia yezoensis	37%	100%
Q8R050	Mus musculus	35%	100%
Q8UH69	Agrobacterium fabrum (strain C58 / ATCC 33970)	27%	100%
Q8W4H7	Arabidopsis thaliana	34%	100%
Q8X7X7	Escherichia coli O157:H7	26%	100%
Q8Z470	Salmonella typhi	25%	100%
Q8ZBP2	Yersinia pestis	26%	100%
Q8ZMF5	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	27%	100%
Q90835	Gallus gallus	34%	100%
Q92005	Danio rerio	33%	100%
Q95VF2	Leishmania donovani	35%	100%
Q96WZ1	Coccidioides immitis (strain RS)	34%	100%
Q976B1	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	33%	100%
Q9HDF6	Serendipita indica	34%	100%
Q9HGI4	Zygosaccharomyces rouxii	34%	97%
Q9HGI6	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	35%	92%
Q9HGI7	Candida maltosa	35%	91%
Q9HGI8	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	34%	92%
Q9PD78	Xylella fastidiosa (strain 9a5c)	28%	100%
Q9W074	Drosophila melanogaster	34%	96%
Q9Y450	Homo sapiens	36%	94%
Q9Y713	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	33%	100%
Q9YAV0	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	37%	100%
Q9YIC0	Oryzias latipes	34%	100%
V5BT94	Trypanosoma cruzi	52%	97%
V5BWI6	Trypanosoma cruzi	30%	100%
V5DGZ5	Trypanosoma cruzi	36%	90%