J domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B6T2_LEIMU

TriTrypDb:

LmxM.34.4040

Length:

390

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6T2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6T2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	298	302	PF00656	0.509
CLV_C14_Caspase3-7	46	50	PF00656	0.607
CLV_NRD_NRD_1	101	103	PF00675	0.397
CLV_NRD_NRD_1	119	121	PF00675	0.464
CLV_NRD_NRD_1	21	23	PF00675	0.361
CLV_NRD_NRD_1	218	220	PF00675	0.634
CLV_NRD_NRD_1	295	297	PF00675	0.644
CLV_NRD_NRD_1	347	349	PF00675	0.569
CLV_PCSK_FUR_1	274	278	PF00082	0.648
CLV_PCSK_FUR_1	345	349	PF00082	0.563
CLV_PCSK_KEX2_1	101	103	PF00082	0.397
CLV_PCSK_KEX2_1	119	121	PF00082	0.464
CLV_PCSK_KEX2_1	125	127	PF00082	0.516
CLV_PCSK_KEX2_1	21	23	PF00082	0.348
CLV_PCSK_KEX2_1	218	220	PF00082	0.675
CLV_PCSK_KEX2_1	25	27	PF00082	0.303
CLV_PCSK_KEX2_1	276	278	PF00082	0.648
CLV_PCSK_KEX2_1	295	297	PF00082	0.587
CLV_PCSK_KEX2_1	347	349	PF00082	0.690
CLV_PCSK_PC1ET2_1	125	127	PF00082	0.523
CLV_PCSK_PC1ET2_1	25	27	PF00082	0.404
CLV_PCSK_PC1ET2_1	276	278	PF00082	0.633
CLV_PCSK_PC7_1	21	27	PF00082	0.304
CLV_PCSK_SKI1_1	21	25	PF00082	0.347
CLV_PCSK_SKI1_1	26	30	PF00082	0.311
CLV_PCSK_SKI1_1	381	385	PF00082	0.490
CLV_PCSK_SKI1_1	54	58	PF00082	0.555
CLV_PCSK_SKI1_1	84	88	PF00082	0.417
DEG_APCC_DBOX_1	100	108	PF00400	0.402
DEG_Nend_Nbox_1	1	3	PF02207	0.432
DEG_SPOP_SBC_1	318	322	PF00917	0.618
DOC_ANK_TNKS_1	177	184	PF00023	0.559
DOC_MAPK_gen_1	21	31	PF00069	0.369
DOC_MAPK_MEF2A_6	22	31	PF00069	0.376
DOC_PP1_RVXF_1	379	385	PF00149	0.479
DOC_PP4_FxxP_1	257	260	PF00568	0.651
DOC_PP4_FxxP_1	384	387	PF00568	0.532
DOC_USP7_MATH_1	13	17	PF00917	0.369
DOC_USP7_MATH_1	182	186	PF00917	0.509
DOC_USP7_MATH_1	205	209	PF00917	0.528
DOC_USP7_MATH_1	260	264	PF00917	0.616
DOC_USP7_MATH_1	341	345	PF00917	0.646
DOC_USP7_MATH_1	65	69	PF00917	0.550
DOC_USP7_MATH_1	75	79	PF00917	0.577
DOC_WW_Pin1_4	153	158	PF00397	0.542
DOC_WW_Pin1_4	203	208	PF00397	0.616
LIG_14-3-3_CanoR_1	160	166	PF00244	0.611
LIG_14-3-3_CanoR_1	254	260	PF00244	0.742
LIG_14-3-3_CanoR_1	287	297	PF00244	0.632
LIG_14-3-3_CanoR_1	351	355	PF00244	0.821
LIG_BIR_III_4	243	247	PF00653	0.548
LIG_BRCT_BRCA1_1	321	325	PF00533	0.611
LIG_BRCT_BRCA1_1	82	86	PF00533	0.617
LIG_CtBP_PxDLS_1	192	196	PF00389	0.529
LIG_FHA_1	377	383	PF00498	0.466
LIG_FHA_1	43	49	PF00498	0.652
LIG_LIR_Gen_1	106	115	PF02991	0.606
LIG_LIR_Gen_1	162	173	PF02991	0.536
LIG_LIR_Gen_1	4	13	PF02991	0.304
LIG_LIR_Gen_1	83	93	PF02991	0.412
LIG_LIR_Nem_3	106	112	PF02991	0.601
LIG_LIR_Nem_3	4	9	PF02991	0.304
LIG_LIR_Nem_3	83	89	PF02991	0.473
LIG_LIR_Nem_3	91	96	PF02991	0.407
LIG_MYND_1	207	211	PF01753	0.628
LIG_SH2_STAP1	105	109	PF00017	0.410
LIG_SH2_STAT3	370	373	PF00017	0.472
LIG_SH2_STAT5	103	106	PF00017	0.421
LIG_SH3_3	181	187	PF00018	0.689
LIG_SH3_3	201	207	PF00018	0.619
LIG_SH3_3	335	341	PF00018	0.647
LIG_SH3_3	361	367	PF00018	0.609
LIG_TRAF2_1	16	19	PF00917	0.369
LIG_TRAF2_1	41	44	PF00917	0.467
MOD_CDK_SPxxK_3	153	160	PF00069	0.552
MOD_CK1_1	203	209	PF00069	0.653
MOD_CK1_1	233	239	PF00069	0.487
MOD_CK2_1	13	19	PF00069	0.304
MOD_CK2_1	163	169	PF00069	0.590
MOD_CK2_1	334	340	PF00069	0.588
MOD_Cter_Amidation	274	277	PF01082	0.512
MOD_Cter_Amidation	345	348	PF01082	0.558
MOD_GlcNHglycan	15	18	PF01048	0.468
MOD_GlcNHglycan	225	228	PF01048	0.509
MOD_GlcNHglycan	243	247	PF01048	0.766
MOD_GlcNHglycan	297	300	PF01048	0.570
MOD_GlcNHglycan	321	324	PF01048	0.527
MOD_GlcNHglycan	340	344	PF01048	0.618
MOD_GlcNHglycan	352	355	PF01048	0.529
MOD_GlcNHglycan	37	40	PF01048	0.492
MOD_GlcNHglycan	63	66	PF01048	0.686
MOD_GSK3_1	159	166	PF00069	0.651
MOD_GSK3_1	199	206	PF00069	0.599
MOD_GSK3_1	282	289	PF00069	0.638
MOD_GSK3_1	327	334	PF00069	0.630
MOD_GSK3_1	35	42	PF00069	0.581
MOD_GSK3_1	372	379	PF00069	0.453
MOD_GSK3_1	61	68	PF00069	0.555
MOD_GSK3_1	80	87	PF00069	0.426
MOD_N-GLC_1	61	66	PF02516	0.567
MOD_NEK2_1	168	173	PF00069	0.523
MOD_NEK2_1	288	293	PF00069	0.627
MOD_NEK2_1	309	314	PF00069	0.589
MOD_NEK2_1	317	322	PF00069	0.654
MOD_PIKK_1	248	254	PF00454	0.648
MOD_PIKK_1	288	294	PF00454	0.661
MOD_PKA_1	295	301	PF00069	0.678
MOD_PKA_2	159	165	PF00069	0.550
MOD_PKA_2	286	292	PF00069	0.600
MOD_PKA_2	295	301	PF00069	0.564
MOD_PKA_2	350	356	PF00069	0.657
MOD_Plk_1	168	174	PF00069	0.545
MOD_Plk_1	199	205	PF00069	0.528
MOD_Plk_1	309	315	PF00069	0.476
MOD_Plk_1	376	382	PF00069	0.459
MOD_Plk_1	43	49	PF00069	0.498
MOD_Plk_1	65	71	PF00069	0.546
MOD_Plk_2-3	44	50	PF00069	0.483
MOD_Plk_4	334	340	PF00069	0.573
MOD_ProDKin_1	153	159	PF00069	0.546
MOD_ProDKin_1	203	209	PF00069	0.617
TRG_ENDOCYTIC_2	109	112	PF00928	0.607
TRG_ENDOCYTIC_2	5	8	PF00928	0.304
TRG_ENDOCYTIC_2	93	96	PF00928	0.374
TRG_ER_diArg_1	101	103	PF00400	0.397
TRG_ER_diArg_1	20	22	PF00400	0.334
TRG_ER_diArg_1	218	220	PF00400	0.569
TRG_ER_diArg_1	295	297	PF00400	0.757
TRG_ER_diArg_1	345	348	PF00400	0.558
TRG_NES_CRM1_1	18	30	PF08389	0.369
TRG_Pf-PMV_PEXEL_1	102	106	PF00026	0.392

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBL0	Leptomonas seymouri	31%	100%
A0A3Q8IIN7	Leishmania donovani	82%	100%
A4HN74	Leishmania braziliensis	66%	100%
A4IBU2	Leishmania infantum	81%	100%
E9AFM9	Leishmania major	81%	99%