Sperm-tail_PG-rich_repeat

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B6S0_LEIMU

TriTrypDb:

LmxM.34.3925

Length:

476

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9B6S0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6S0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	126	130	PF00656	0.638
CLV_C14_Caspase3-7	209	213	PF00656	0.455
CLV_NRD_NRD_1	150	152	PF00675	0.362
CLV_NRD_NRD_1	163	165	PF00675	0.668
CLV_NRD_NRD_1	267	269	PF00675	0.629
CLV_NRD_NRD_1	304	306	PF00675	0.345
CLV_NRD_NRD_1	307	309	PF00675	0.681
CLV_NRD_NRD_1	353	355	PF00675	0.628
CLV_NRD_NRD_1	425	427	PF00675	0.719
CLV_PCSK_FUR_1	305	309	PF00082	0.381
CLV_PCSK_KEX2_1	150	152	PF00082	0.362
CLV_PCSK_KEX2_1	267	269	PF00082	0.627
CLV_PCSK_KEX2_1	304	306	PF00082	0.381
CLV_PCSK_KEX2_1	307	309	PF00082	0.698
CLV_PCSK_KEX2_1	31	33	PF00082	0.389
CLV_PCSK_KEX2_1	352	354	PF00082	0.621
CLV_PCSK_KEX2_1	425	427	PF00082	0.748
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.389
CLV_PCSK_PC1ET2_1	352	354	PF00082	0.720
CLV_PCSK_PC7_1	348	354	PF00082	0.677
DEG_APCC_KENBOX_2	9	13	PF00400	0.580
DEG_Nend_UBRbox_2	1	3	PF02207	0.749
DEG_SCF_TRCP1_1	129	135	PF00400	0.643
DOC_CDC14_PxL_1	1	9	PF14671	0.718
DOC_PP1_RVXF_1	432	439	PF00149	0.693
DOC_PP2B_LxvP_1	67	70	PF13499	0.638
DOC_PP4_FxxP_1	120	123	PF00568	0.562
DOC_PP4_FxxP_1	312	315	PF00568	0.766
DOC_PP4_FxxP_1	58	61	PF00568	0.607
DOC_USP7_MATH_1	123	127	PF00917	0.643
DOC_USP7_MATH_1	238	242	PF00917	0.595
DOC_USP7_MATH_1	279	283	PF00917	0.654
DOC_USP7_MATH_1	317	321	PF00917	0.576
DOC_USP7_MATH_1	41	45	PF00917	0.501
DOC_USP7_MATH_1	68	72	PF00917	0.598
DOC_USP7_MATH_1	81	85	PF00917	0.611
DOC_USP7_MATH_2	232	238	PF00917	0.714
DOC_WW_Pin1_4	210	215	PF00397	0.642
DOC_WW_Pin1_4	292	297	PF00397	0.697
DOC_WW_Pin1_4	323	328	PF00397	0.599
DOC_WW_Pin1_4	444	449	PF00397	0.635
DOC_WW_Pin1_4	94	99	PF00397	0.608
LIG_14-3-3_CanoR_1	109	115	PF00244	0.373
LIG_14-3-3_CanoR_1	353	359	PF00244	0.579
LIG_14-3-3_CanoR_1	437	444	PF00244	0.652
LIG_BIR_III_2	440	444	PF00653	0.446
LIG_BIR_III_4	253	257	PF00653	0.640
LIG_BRCT_BRCA1_1	116	120	PF00533	0.581
LIG_BRCT_BRCA1_1	192	196	PF00533	0.612
LIG_BRCT_BRCA1_1	232	236	PF00533	0.694
LIG_BRCT_BRCA1_1	242	246	PF00533	0.675
LIG_BRCT_BRCA1_1	276	280	PF00533	0.651
LIG_BRCT_BRCA1_1	71	75	PF00533	0.635
LIG_BRCT_BRCA1_1	78	82	PF00533	0.542
LIG_BRCT_BRCA1_1	85	89	PF00533	0.694
LIG_FHA_1	216	222	PF00498	0.559
LIG_FHA_1	259	265	PF00498	0.596
LIG_FHA_1	403	409	PF00498	0.745
LIG_FHA_1	470	476	PF00498	0.655
LIG_FHA_1	72	78	PF00498	0.638
LIG_LIR_Apic_2	117	123	PF02991	0.562
LIG_LIR_Apic_2	311	315	PF02991	0.759
LIG_LIR_Apic_2	378	384	PF02991	0.585
LIG_LIR_Apic_2	55	61	PF02991	0.667
LIG_LIR_Gen_1	282	292	PF02991	0.675
LIG_LIR_Gen_1	413	422	PF02991	0.745
LIG_LIR_Nem_3	157	161	PF02991	0.626
LIG_LIR_Nem_3	233	239	PF02991	0.640
LIG_LIR_Nem_3	282	287	PF02991	0.672
LIG_LIR_Nem_3	413	417	PF02991	0.752
LIG_MLH1_MIPbox_1	232	236	PF16413	0.521
LIG_MYND_1	180	184	PF01753	0.714
LIG_Pex14_2	325	329	PF04695	0.709
LIG_PTB_Apo_2	139	146	PF02174	0.537
LIG_PTB_Apo_2	388	395	PF02174	0.695
LIG_PTB_Phospho_1	139	145	PF10480	0.537
LIG_SH2_CRK	414	418	PF00017	0.568
LIG_SH2_CRK	64	68	PF00017	0.648
LIG_SH2_NCK_1	145	149	PF00017	0.562
LIG_SH2_SRC	219	222	PF00017	0.679
LIG_SH2_STAP1	124	128	PF00017	0.729
LIG_SH2_STAP1	377	381	PF00017	0.605
LIG_SH2_STAT5	118	121	PF00017	0.525
LIG_SH2_STAT5	235	238	PF00017	0.696
LIG_SH2_STAT5	260	263	PF00017	0.599
LIG_SH2_STAT5	414	417	PF00017	0.673
LIG_SH3_3	163	169	PF00018	0.701
LIG_SH3_3	405	411	PF00018	0.663
LIG_SxIP_EBH_1	352	365	PF03271	0.454
LIG_TRAF2_1	371	374	PF00917	0.429
LIG_WRC_WIRS_1	355	360	PF05994	0.577
MOD_CK1_1	241	247	PF00069	0.705
MOD_CK1_1	71	77	PF00069	0.609
MOD_CK1_1	84	90	PF00069	0.614
MOD_Cter_Amidation	423	426	PF01082	0.630
MOD_GlcNHglycan	120	123	PF01048	0.449
MOD_GlcNHglycan	125	128	PF01048	0.689
MOD_GlcNHglycan	129	132	PF01048	0.397
MOD_GlcNHglycan	236	239	PF01048	0.591
MOD_GlcNHglycan	274	277	PF01048	0.623
MOD_GlcNHglycan	281	284	PF01048	0.564
MOD_GlcNHglycan	340	343	PF01048	0.700
MOD_GlcNHglycan	366	369	PF01048	0.704
MOD_GlcNHglycan	444	447	PF01048	0.643
MOD_GlcNHglycan	52	55	PF01048	0.736
MOD_GSK3_1	114	121	PF00069	0.449
MOD_GSK3_1	123	130	PF00069	0.394
MOD_GSK3_1	14	21	PF00069	0.616
MOD_GSK3_1	160	167	PF00069	0.509
MOD_GSK3_1	191	198	PF00069	0.579
MOD_GSK3_1	230	237	PF00069	0.627
MOD_GSK3_1	270	277	PF00069	0.660
MOD_GSK3_1	323	330	PF00069	0.606
MOD_GSK3_1	385	392	PF00069	0.636
MOD_GSK3_1	460	467	PF00069	0.561
MOD_GSK3_1	99	106	PF00069	0.454
MOD_N-GLC_1	35	40	PF02516	0.404
MOD_N-GLC_1	390	395	PF02516	0.726
MOD_N-GLC_1	42	47	PF02516	0.638
MOD_N-GLC_1	464	469	PF02516	0.561
MOD_N-GLC_1	94	99	PF02516	0.608
MOD_NEK2_1	132	137	PF00069	0.625
MOD_NEK2_1	239	244	PF00069	0.570
MOD_NEK2_1	318	323	PF00069	0.663
MOD_NEK2_1	389	394	PF00069	0.625
MOD_NEK2_1	402	407	PF00069	0.656
MOD_NEK2_1	417	422	PF00069	0.624
MOD_NEK2_1	42	47	PF00069	0.598
MOD_NEK2_1	460	465	PF00069	0.571
MOD_PIKK_1	327	333	PF00454	0.727
MOD_PIKK_1	69	75	PF00454	0.529
MOD_PIKK_1	76	82	PF00454	0.678
MOD_PK_1	191	197	PF00069	0.621
MOD_PKA_1	164	170	PF00069	0.456
MOD_PKA_2	108	114	PF00069	0.262
MOD_PKA_2	14	20	PF00069	0.739
MOD_PKA_2	436	442	PF00069	0.679
MOD_PKB_1	268	276	PF00069	0.447
MOD_Plk_1	373	379	PF00069	0.727
MOD_Plk_1	390	396	PF00069	0.614
MOD_Plk_1	42	48	PF00069	0.703
MOD_Plk_1	464	470	PF00069	0.559
MOD_Plk_1	84	90	PF00069	0.614
MOD_Plk_4	191	197	PF00069	0.652
MOD_Plk_4	455	461	PF00069	0.556
MOD_ProDKin_1	210	216	PF00069	0.648
MOD_ProDKin_1	292	298	PF00069	0.461
MOD_ProDKin_1	323	329	PF00069	0.603
MOD_ProDKin_1	444	450	PF00069	0.638
MOD_ProDKin_1	94	100	PF00069	0.398
TRG_DiLeu_BaEn_2	84	90	PF01217	0.692
TRG_DiLeu_BaEn_4	2	8	PF01217	0.741
TRG_DiLeu_BaLyEn_6	334	339	PF01217	0.687
TRG_DiLeu_LyEn_5	2	7	PF01217	0.711
TRG_ENDOCYTIC_2	284	287	PF00928	0.669
TRG_ENDOCYTIC_2	414	417	PF00928	0.723
TRG_ENDOCYTIC_2	64	67	PF00928	0.628
TRG_ER_diArg_1	150	152	PF00400	0.449
TRG_ER_diArg_1	266	268	PF00400	0.628
TRG_ER_diArg_1	269	272	PF00400	0.617
TRG_ER_diArg_1	304	307	PF00400	0.484
TRG_ER_diArg_1	353	356	PF00400	0.598
TRG_ER_diArg_1	425	427	PF00400	0.743
TRG_ER_FFAT_2	233	241	PF00635	0.420
TRG_NLS_MonoExtC_3	351	356	PF00514	0.672
TRG_NLS_MonoExtN_4	350	356	PF00514	0.671

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAQ4	Leptomonas seymouri	61%	99%
A0A0S4IX55	Bodo saltans	30%	89%
A0A1X0P6L3	Trypanosomatidae	37%	100%
A0A3Q8IGK1	Leishmania donovani	89%	100%
A0A3R7LN85	Trypanosoma rangeli	35%	100%
A4HN63	Leishmania braziliensis	78%	100%
A4IBT0	Leishmania infantum	89%	100%
C9ZYT8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9AFL7	Leishmania major	90%	100%
V5C2R9	Trypanosoma cruzi	34%	100%