Calmodulin-like protein (Ef hand containing protein)

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

calmodulin-like protein

Species:

Leishmania mexicana

UniProt:

E9B6R7_LEIMU

TriTrypDb:

LmxM.34.3890

Length:

139

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005815	microtubule organizing center	2	1
GO:0005930	axoneme	2	1
GO:0016459	myosin complex	2	1
GO:0016460	myosin II complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0036064	ciliary basal body	3	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9B6R7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6R7

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	11
GO:0005509	calcium ion binding	5	11
GO:0043167	ion binding	2	11
GO:0043169	cation binding	3	11
GO:0046872	metal ion binding	4	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	2	6	PF00082	0.455
CLV_PCSK_SKI1_1	68	72	PF00082	0.312
DEG_Nend_UBRbox_1	1	4	PF02207	0.537
DOC_USP7_MATH_1	15	19	PF00917	0.428
DOC_USP7_UBL2_3	120	124	PF12436	0.409
DOC_USP7_UBL2_3	56	60	PF12436	0.509
LIG_14-3-3_CanoR_1	88	98	PF00244	0.312
LIG_APCC_ABBA_1	126	131	PF00400	0.533
LIG_FHA_1	79	85	PF00498	0.339
LIG_FHA_2	39	45	PF00498	0.447
LIG_FHA_2	91	97	PF00498	0.312
LIG_LIR_Gen_1	3	11	PF02991	0.467
LIG_LIR_Nem_3	100	106	PF02991	0.446
LIG_LIR_Nem_3	3	8	PF02991	0.439
LIG_LIR_Nem_3	69	74	PF02991	0.331
LIG_LIR_Nem_3	86	90	PF02991	0.312
LIG_SH2_STAP1	118	122	PF00017	0.407
LIG_SH2_STAP1	50	54	PF00017	0.431
LIG_SUMO_SIM_par_1	79	86	PF11976	0.323
LIG_TRAF2_1	30	33	PF00917	0.474
LIG_UBA3_1	90	97	PF00899	0.312
MOD_CK1_1	18	24	PF00069	0.426
MOD_CK2_1	80	86	PF00069	0.312
MOD_CK2_1	90	96	PF00069	0.312
MOD_GlcNHglycan	133	136	PF01048	0.693
MOD_GSK3_1	127	134	PF00069	0.657
MOD_NEK2_1	78	83	PF00069	0.318
MOD_SUMO_rev_2	31	35	PF00179	0.512
MOD_SUMO_rev_2	55	61	PF00179	0.643
MOD_SUMO_rev_2	6	15	PF00179	0.464
TRG_DiLeu_BaEn_1	102	107	PF01217	0.441
TRG_DiLeu_BaEn_1	3	8	PF01217	0.439
TRG_ENDOCYTIC_2	118	121	PF00928	0.403
TRG_ENDOCYTIC_2	50	53	PF00928	0.436
TRG_Pf-PMV_PEXEL_1	104	108	PF00026	0.441

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P206	Leptomonas seymouri	38%	93%
A0A0N0P4B4	Leptomonas seymouri	92%	96%
A0A0N0P8Y6	Leptomonas seymouri	27%	77%
A0A0N1PDC0	Leptomonas seymouri	30%	90%
A0A0S4INC8	Bodo saltans	27%	74%
A0A0S4IS38	Bodo saltans	38%	93%
A0A0S4IXG9	Bodo saltans	88%	96%
A0A0S4J7U6	Bodo saltans	32%	86%
A0A0S4JFC8	Bodo saltans	38%	82%
A0A0S4JFY6	Bodo saltans	32%	94%
A0A1X0NMM5	Trypanosomatidae	38%	93%
A0A1X0NXC6	Trypanosomatidae	30%	87%
A0A1X0NYH1	Trypanosomatidae	26%	90%
A0A1X0P607	Trypanosomatidae	88%	96%
A0A1X0P9X3	Trypanosomatidae	26%	77%
A0A3Q8IHK5	Leishmania donovani	27%	77%
A0A3S7WW96	Leishmania donovani	29%	90%
A0A3S7X1A1	Leishmania donovani	26%	90%
A0A3S7X9Z4	Leishmania donovani	99%	100%
A0A422MQ47	Trypanosoma rangeli	38%	100%
A0A422N447	Trypanosoma rangeli	88%	98%
A0A422N5Z1	Trypanosoma rangeli	24%	73%
A0A422NIM0	Trypanosoma rangeli	34%	90%
A0A422P0I1	Trypanosoma rangeli	27%	77%
A0JNJ5	Bos taurus	38%	72%
A0T2M3	Hesperocyparis arizonica	34%	84%
A2WN93	Oryza sativa subsp. indica	39%	93%
A2WNH1	Oryza sativa subsp. indica	38%	93%
A2Y609	Oryza sativa subsp. indica	40%	93%
A3E3H0	Pfiesteria piscicida	38%	93%
A3E4D8	Prorocentrum minimum	38%	93%
A3E4F9	Karlodinium veneficum	38%	93%
A4H5R9	Leishmania braziliensis	38%	100%
A4HAV0	Leishmania braziliensis	27%	100%
A4HBM1	Leishmania braziliensis	32%	100%
A4HCI2	Leishmania braziliensis	26%	100%
A4HN60	Leishmania braziliensis	90%	100%
A4HU13	Leishmania infantum	38%	93%
A4HZA9	Leishmania infantum	29%	90%
A4I3F5	Leishmania infantum	26%	90%
A4IA04	Leishmania infantum	27%	77%
A4IBS7	Leishmania infantum	99%	100%
A4IF97	Bos taurus	27%	81%
A4UHC0	Alexandrium fundyense	38%	93%
A8CEP3	Saccharina japonica	37%	93%
A8I1Q0	Heterocapsa triquetra	38%	93%
B1PSN3	Leishmania donovani	38%	93%
C9ZML6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	76%
C9ZYU5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	84%	99%
D0A7Y5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	90%
D0A9H8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	94%
D0A9H9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	93%
D2DGW3	Tyrophagus putrescentiae	26%	91%
E9AFL3	Leishmania major	99%	100%
E9AMU3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9AUY9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9AZP3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9B525	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
F1RRT2	Sus scrofa	34%	71%
O00897	Dictyostelium discoideum	32%	93%
O02367	Ciona intestinalis	37%	93%
O14008	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	97%
O14950	Homo sapiens	27%	81%
O15182	Homo sapiens	26%	83%
O16305	Caenorhabditis elegans	37%	93%
O23320	Arabidopsis thaliana	35%	92%
O35648	Mus musculus	26%	83%
O60041	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	34%	95%
O64943	Juniperus oxycedrus	34%	84%
O82018	Mougeotia scalaris	37%	93%
O82659	Arabidopsis thaliana	30%	82%
O94739	Pleurotus ostreatus	37%	93%
O96081	Halocynthia roretzi	36%	93%
O96102	Physarum polycephalum	36%	93%
O97341	Suberites domuncula	36%	93%
P02585	Homo sapiens	30%	87%
P02586	Oryctolagus cuniculus	30%	87%
P02587	Sus scrofa	29%	87%
P02588	Gallus gallus	31%	85%
P02589	Pelophylax lessonae	30%	86%
P02591	Oryctolagus cuniculus	30%	86%
P02594	Electrophorus electricus	38%	93%
P02595	Patinopecten sp.	37%	93%
P02597	Gallus gallus	39%	93%
P02598	Tetrahymena pyriformis	38%	93%
P02599	Dictyostelium discoideum	36%	91%
P02600	Rattus norvegicus	38%	74%
P02602	Oryctolagus cuniculus	38%	72%
P02604	Gallus gallus	38%	72%
P02605	Gallus gallus	38%	93%
P02606	Gallus gallus	36%	72%
P02607	Gallus gallus	37%	92%
P02612	Gallus gallus	28%	81%
P04352	Chlamydomonas reinhardtii	36%	85%
P04353	Spinacia oleracea	39%	93%
P04464	Triticum aestivum	40%	93%
P04630	Caenorhabditis elegans	37%	86%
P05419	Gallus gallus	36%	100%
P05434	Chlamydomonas reinhardtii	34%	82%
P05932	Arbacia punctulata	36%	100%
P05933	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	93%
P05936	Coturnix japonica	31%	86%
P05945	Todarodes pacificus	31%	87%
P05976	Homo sapiens	37%	72%
P05977	Mus musculus	38%	74%
P06787	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	95%
P07290	Mizuhopecten yessoensis	29%	89%
P07291	Argopecten irradians	29%	89%
P07462	Halocynthia roretzi	34%	92%
P07463	Paramecium tetraurelia	35%	93%
P08051	Spisula sachalinensis	24%	87%
P08053	Physarum polycephalum	26%	95%
P08590	Homo sapiens	34%	71%
P09540	Gallus gallus	34%	75%
P09541	Mus musculus	34%	72%
P09542	Mus musculus	34%	68%
P09860	Gallus gallus	31%	86%
P0DH95	Arabidopsis thaliana	40%	93%
P0DH96	Arabidopsis thaliana	40%	93%
P0DH97	Arabidopsis thaliana	39%	93%
P0DH98	Arabidopsis thaliana	39%	93%
P0DP23	Homo sapiens	37%	93%
P0DP24	Homo sapiens	37%	93%
P0DP25	Homo sapiens	37%	93%
P0DP26	Mus musculus	37%	93%
P0DP27	Mus musculus	37%	93%
P0DP28	Mus musculus	37%	93%
P0DP29	Rattus norvegicus	37%	93%
P0DP30	Rattus norvegicus	37%	93%
P0DP31	Rattus norvegicus	37%	93%
P0DP33	Xenopus laevis	37%	93%
P0DP34	Xenopus laevis	37%	93%
P0DP35	Xenopus laevis	37%	93%
P10246	Meleagris gallopavo	32%	86%
P11118	Euglena gracilis	39%	93%
P11120	Pleurotus cornucopiae	37%	93%
P11121	Pyuridae sp.	36%	93%
P12829	Homo sapiens	35%	71%
P13832	Rattus norvegicus	28%	81%
P13868	Solanum tuberosum	38%	93%
P14533	Doryteuthis pealeii	33%	93%
P14649	Homo sapiens	37%	67%
P15094	Achlya klebsiana	35%	93%
P15159	Tachypleus tridentatus	27%	91%
P16409	Rattus norvegicus	34%	70%
P17209	Rattus norvegicus	34%	72%
P17928	Medicago sativa	39%	93%
P18061	Trypanosoma cruzi	38%	93%
P18666	Rattus norvegicus	27%	81%
P19105	Homo sapiens	28%	81%
P19123	Mus musculus	30%	86%
P20801	Mus musculus	31%	87%
P21251	Stichopus japonicus	36%	93%
P23286	Candida albicans	32%	93%
P24032	Gallus gallus	27%	81%
P24044	Plasmodium falciparum	38%	93%
P24844	Homo sapiens	28%	81%
P27161	Solanum lycopersicum	38%	93%
P27163	Petunia hybrida	38%	93%
P27164	Petunia hybrida	39%	76%
P27165	Phytophthora infestans	37%	93%
P27166	Stylonychia lemnae	38%	93%
P27482	Homo sapiens	37%	93%
P29269	Sus scrofa	28%	81%
P30187	Arabidopsis thaliana	29%	73%
P41040	Zea mays	40%	93%
P41041	Pneumocystis carinii	38%	92%
P41208	Homo sapiens	30%	81%
P41209	Mus musculus	30%	81%
P41210	Atriplex nummularia	29%	83%
P43645	Spermatozopsis similis	29%	94%
P43646	Tetraselmis striata	32%	94%
P48593	Drosophila melanogaster	27%	72%
P48976	Malus domestica	39%	93%
P49258	Drosophila melanogaster	34%	94%
P53014	Caenorhabditis elegans	33%	91%
P53141	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	93%
P53440	Naegleria gruberi	36%	90%
P53441	Naegleria gruberi	31%	81%
P54213	Dunaliella salina	29%	82%
P54357	Drosophila melanogaster	38%	95%
P59220	Arabidopsis thaliana	39%	93%
P60204	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	93%
P60205	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	35%	93%
P60206	Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)	35%	93%
P60660	Homo sapiens	39%	92%
P60661	Bos taurus	39%	92%
P60662	Sus scrofa	39%	92%
P61859	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	35%	93%
P61860	Colletotrichum trifolii	35%	93%
P61861	Colletotrichum gloeosporioides	35%	93%
P62144	Anas platyrhynchos	37%	93%
P62145	Aplysia californica	36%	93%
P62146	Arbacia punctulata	36%	98%
P62147	Branchiostoma floridae	36%	93%
P62148	Branchiostoma lanceolatum	36%	93%
P62149	Gallus gallus	37%	93%
P62150	Oryzias latipes	37%	100%
P62151	Tetronarce californica	37%	93%
P62152	Drosophila melanogaster	36%	93%
P62153	Halocynthia roretzi	36%	93%
P62154	Locusta migratoria	36%	93%
P62156	Oncorhynchus sp.	37%	93%
P62157	Bos taurus	37%	93%
P62160	Oryctolagus cuniculus	37%	93%
P62162	Hordeum vulgare	39%	93%
P62163	Glycine max	39%	93%
P62184	Renilla reniformis	37%	93%
P62199	Petunia hybrida	39%	93%
P62200	Daucus carota	39%	93%
P62201	Lilium longiflorum	39%	93%
P62202	Bryonia dioica	39%	93%
P62203	Plasmodium falciparum (isolate 3D7)	38%	93%
P63315	Bos taurus	30%	86%
P63316	Homo sapiens	30%	86%
P63317	Sus scrofa	30%	86%
P69097	Trypanosoma brucei brucei	39%	93%
P69098	Trypanosoma brucei gambiense	39%	93%
P81660	Anguilla anguilla	32%	87%
P82159	Chelon ramada	33%	75%
P82160	Chelon ramada	36%	94%
P84339	Agaricus bisporus	37%	93%
P85100	Bos taurus	35%	70%
P93087	Capsicum annuum	38%	93%
P93171	Helianthus annuus	39%	93%
Q03509	Arabidopsis thaliana	39%	93%
Q06827	Scherffelia dubia	32%	83%
Q09196	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	99%
Q09510	Caenorhabditis elegans	29%	81%
Q0IQB6	Oryza sativa subsp. japonica	29%	76%
Q0IUU4	Oryza sativa subsp. japonica	30%	76%
Q0JNL7	Oryza sativa subsp. japonica	38%	93%
Q0JNS6	Oryza sativa subsp. japonica	39%	93%
Q12798	Homo sapiens	28%	81%
Q17133	Branchiostoma floridae	31%	93%
Q24956	Giardia intestinalis	32%	79%
Q2R1Z5	Oryza sativa subsp. japonica	32%	82%
Q2TBN3	Bos taurus	30%	81%
Q32LE3	Bos taurus	30%	81%
Q338P8	Oryza sativa subsp. japonica	30%	73%
Q39752	Fagus sylvatica	38%	94%
Q3T0E8	Bos taurus	25%	91%
Q3THE2	Mus musculus	27%	81%
Q40302	Macrocystis pyrifera	38%	93%
Q40642	Oryza sativa subsp. indica	37%	74%
Q41420	Solanum tuberosum	36%	100%
Q4Q2W1	Leishmania major	27%	100%
Q4Q8I9	Leishmania major	26%	100%
Q4QCJ3	Leishmania major	29%	100%
Q4QHT2	Leishmania major	38%	100%
Q5E9E2	Bos taurus	28%	81%
Q5R844	Pongo abelii	39%	92%
Q5R887	Pongo abelii	34%	71%
Q5RAD2	Pongo abelii	37%	93%
Q5RBA4	Pongo abelii	28%	81%
Q5RC34	Pongo abelii	28%	81%
Q5U206	Rattus norvegicus	38%	93%
Q5XGC7	Xenopus tropicalis	28%	91%
Q60605	Mus musculus	39%	92%
Q64119	Rattus norvegicus	38%	92%
Q64122	Rattus norvegicus	28%	81%
Q682T9	Arabidopsis thaliana	39%	93%
Q6F332	Oryza sativa subsp. japonica	40%	93%
Q6F334	Oryza sativa subsp. japonica	24%	90%
Q6IT78	Ctenopharyngodon idella	37%	93%
Q6L4D4	Oryza sativa subsp. japonica	29%	69%
Q6P0G6	Danio rerio	34%	73%
Q6PI52	Danio rerio	37%	93%
Q6R520	Oreochromis mossambicus	35%	93%
Q6YNX6	Ovis aries	37%	93%
Q71UH5	Globisporangium splendens	37%	93%
Q71UH6	Perca flavescens	37%	93%
Q7DMN9	Solanum tuberosum	38%	93%
Q7DMP0	Solanum tuberosum	37%	100%
Q7F0J0	Oryza sativa subsp. japonica	28%	82%
Q7T3T2	Epinephelus akaara	37%	93%
Q7Y052	Euphorbia characias	39%	93%
Q7Z2B8	Dictyostelium discoideum	37%	95%
Q84MN0	Oryza sativa subsp. japonica	32%	90%
Q84VG0	Oryza sativa subsp. japonica	32%	94%
Q8CI43	Mus musculus	37%	67%
Q8K4K1	Mus musculus	26%	83%
Q8RZB5	Oryza sativa subsp. japonica	30%	75%
Q8S1Y9	Oryza sativa subsp. japonica	36%	74%
Q8STF0	Strongylocentrotus intermedius	36%	89%
Q8VZ50	Arabidopsis thaliana	36%	94%
Q8X187	Paxillus involutus	36%	93%
Q91WQ9	Mus musculus	24%	91%
Q948R0	Oryza sativa subsp. japonica	32%	84%
Q94AZ4	Arabidopsis thaliana	34%	94%
Q95NI4	Halichondria okadai	36%	93%
Q95NR9	Metridium senile	36%	93%
Q96GE6	Homo sapiens	26%	71%
Q9BLG0	Todarodes pacificus	24%	94%
Q9CQ19	Mus musculus	28%	81%
Q9D6P8	Mus musculus	38%	93%
Q9FYK2	Arabidopsis thaliana	28%	75%
Q9FZ75	Arabidopsis thaliana	26%	89%
Q9GRJ1	Lumbricus rubellus	36%	93%
Q9HFY6	Blastocladiella emersonii	37%	93%
Q9LIK5	Arabidopsis thaliana	35%	80%
Q9M7R0	Olea europaea	30%	81%
Q9NZT1	Homo sapiens	30%	95%
Q9R1K9	Mus musculus	30%	81%
Q9S744	Arabidopsis thaliana	28%	92%
Q9SN89	Arabidopsis thaliana	30%	76%
Q9U6D3	Myxine glutinosa	36%	93%
Q9UB37	Branchiostoma lanceolatum	35%	93%
Q9UUG5	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	76%
Q9UWF0	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	35%	93%
Q9XVI9	Caenorhabditis elegans	32%	98%
Q9XZP2	Branchiostoma floridae	35%	93%