DDB1- and CUL4-associated factor 13

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

WD domain, G-beta repeat/Sof1-like domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9B6R6_LEIMU

TriTrypDb:

LmxM.34.3880

Length:

444

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	12
GO:0005840	ribosome	5	12
GO:0032991	protein-containing complex	1	12
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12
GO:1990904	ribonucleoprotein complex	2	12
GO:0030684	preribosome	3	1
GO:0032040	small-subunit processome	4	1

Expansion

Sequence features

E9B6R6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6R6

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006364	rRNA processing	8	12
GO:0006396	RNA processing	6	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0016070	RNA metabolic process	5	12
GO:0016072	rRNA metabolic process	7	12
GO:0016567	protein ubiquitination	7	12
GO:0019538	protein metabolic process	3	12
GO:0032446	protein modification by small protein conjugation	6	12
GO:0034470	ncRNA processing	7	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0034660	ncRNA metabolic process	6	12
GO:0036211	protein modification process	4	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043412	macromolecule modification	4	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0046483	heterocycle metabolic process	3	12
GO:0070647	protein modification by small protein conjugation or removal	5	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:1901564	organonitrogen compound metabolic process	3	12
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	1
GO:0030490	maturation of SSU-rRNA	9	1

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	316	320	PF00656	0.581
CLV_NRD_NRD_1	409	411	PF00675	0.325
CLV_NRD_NRD_1	436	438	PF00675	0.566
CLV_NRD_NRD_1	99	101	PF00675	0.566
CLV_PCSK_FUR_1	100	104	PF00082	0.387
CLV_PCSK_KEX2_1	102	104	PF00082	0.378
CLV_PCSK_KEX2_1	327	329	PF00082	0.308
CLV_PCSK_KEX2_1	392	394	PF00082	0.311
CLV_PCSK_KEX2_1	409	411	PF00082	0.315
CLV_PCSK_KEX2_1	416	418	PF00082	0.298
CLV_PCSK_KEX2_1	436	438	PF00082	0.344
CLV_PCSK_PC1ET2_1	102	104	PF00082	0.340
CLV_PCSK_PC1ET2_1	327	329	PF00082	0.308
CLV_PCSK_PC1ET2_1	392	394	PF00082	0.347
CLV_PCSK_PC1ET2_1	416	418	PF00082	0.311
CLV_PCSK_PC1ET2_1	436	438	PF00082	0.344
CLV_PCSK_SKI1_1	132	136	PF00082	0.251
CLV_PCSK_SKI1_1	220	224	PF00082	0.362
CLV_PCSK_SKI1_1	276	280	PF00082	0.251
CLV_PCSK_SKI1_1	284	288	PF00082	0.243
CLV_PCSK_SKI1_1	379	383	PF00082	0.318
CLV_PCSK_SKI1_1	402	406	PF00082	0.389
CLV_PCSK_SKI1_1	409	413	PF00082	0.335
DOC_ANK_TNKS_1	109	116	PF00023	0.497
DOC_MAPK_gen_1	132	141	PF00069	0.461
DOC_MAPK_gen_1	382	391	PF00069	0.324
DOC_PP1_RVXF_1	36	43	PF00149	0.450
DOC_PP4_FxxP_1	55	58	PF00568	0.399
DOC_USP7_MATH_1	159	163	PF00917	0.345
DOC_USP7_MATH_1	173	177	PF00917	0.341
DOC_USP7_MATH_1	299	303	PF00917	0.502
DOC_USP7_MATH_1	339	343	PF00917	0.504
DOC_USP7_MATH_1	84	88	PF00917	0.517
DOC_USP7_UBL2_3	412	416	PF12436	0.317
DOC_USP7_UBL2_3	432	436	PF12436	0.351
DOC_WW_Pin1_4	116	121	PF00397	0.481
DOC_WW_Pin1_4	289	294	PF00397	0.542
DOC_WW_Pin1_4	335	340	PF00397	0.467
LIG_14-3-3_CanoR_1	110	114	PF00244	0.497
LIG_14-3-3_CanoR_1	18	25	PF00244	0.543
LIG_14-3-3_CanoR_1	192	196	PF00244	0.436
LIG_14-3-3_CanoR_1	228	237	PF00244	0.475
LIG_14-3-3_CanoR_1	284	293	PF00244	0.488
LIG_14-3-3_CanoR_1	354	364	PF00244	0.517
LIG_14-3-3_CanoR_1	437	441	PF00244	0.596
LIG_BRCT_BRCA1_1	201	205	PF00533	0.475
LIG_BRCT_BRCA1_2	201	207	PF00533	0.479
LIG_FHA_1	185	191	PF00498	0.414
LIG_FHA_1	208	214	PF00498	0.368
LIG_FHA_1	41	47	PF00498	0.380
LIG_FHA_1	83	89	PF00498	0.542
LIG_FHA_2	172	178	PF00498	0.340
LIG_FHA_2	255	261	PF00498	0.365
LIG_FHA_2	285	291	PF00498	0.456
LIG_LIR_Apic_2	52	58	PF02991	0.390
LIG_LIR_Gen_1	157	167	PF02991	0.358
LIG_LIR_Gen_1	202	213	PF02991	0.476
LIG_LIR_Gen_1	386	394	PF02991	0.346
LIG_LIR_Nem_3	157	163	PF02991	0.361
LIG_LIR_Nem_3	202	208	PF02991	0.465
LIG_LIR_Nem_3	386	391	PF02991	0.325
LIG_LIR_Nem_3	439	443	PF02991	0.594
LIG_Pex14_1	137	141	PF04695	0.536
LIG_Pex14_2	154	158	PF04695	0.536
LIG_Pex14_2	167	171	PF04695	0.422
LIG_Pex14_2	55	59	PF04695	0.401
LIG_SH2_GRB2like	385	388	PF00017	0.393
LIG_SH2_SRC	343	346	PF00017	0.467
LIG_SH2_STAP1	333	337	PF00017	0.542
LIG_SH2_STAP1	385	389	PF00017	0.429
LIG_SH2_STAT5	265	268	PF00017	0.353
LIG_SH2_STAT5	343	346	PF00017	0.456
LIG_SH3_2	363	368	PF14604	0.308
LIG_SH3_3	246	252	PF00018	0.376
LIG_SH3_3	269	275	PF00018	0.430
LIG_SH3_3	360	366	PF00018	0.308
LIG_SH3_4	432	439	PF00018	0.531
LIG_TRAF2_1	143	146	PF00917	0.555
MOD_CK1_1	231	237	PF00069	0.527
MOD_CK1_1	358	364	PF00069	0.373
MOD_CK1_1	72	78	PF00069	0.517
MOD_CK1_1	79	85	PF00069	0.497
MOD_CK2_1	343	349	PF00069	0.456
MOD_CK2_1	5	11	PF00069	0.460
MOD_GlcNHglycan	126	129	PF01048	0.256
MOD_GlcNHglycan	230	233	PF01048	0.553
MOD_GlcNHglycan	345	348	PF01048	0.246
MOD_GSK3_1	126	133	PF00069	0.526
MOD_GSK3_1	167	174	PF00069	0.401
MOD_GSK3_1	239	246	PF00069	0.467
MOD_GSK3_1	289	296	PF00069	0.479
MOD_GSK3_1	299	306	PF00069	0.410
MOD_GSK3_1	3	10	PF00069	0.475
MOD_GSK3_1	313	320	PF00069	0.466
MOD_GSK3_1	335	342	PF00069	0.481
MOD_GSK3_1	72	79	PF00069	0.573
MOD_LATS_1	282	288	PF00433	0.542
MOD_N-GLC_1	184	189	PF02516	0.418
MOD_NEK2_1	167	172	PF00069	0.419
MOD_NEK2_1	240	245	PF00069	0.377
MOD_NEK2_1	312	317	PF00069	0.533
MOD_NEK2_1	323	328	PF00069	0.328
MOD_NEK2_1	405	410	PF00069	0.425
MOD_NEK2_2	293	298	PF00069	0.560
MOD_NEK2_2	377	382	PF00069	0.324
MOD_PIKK_1	184	190	PF00454	0.447
MOD_PIKK_1	226	232	PF00454	0.418
MOD_PIKK_1	299	305	PF00454	0.517
MOD_PK_1	317	323	PF00069	0.444
MOD_PKA_1	392	398	PF00069	0.343
MOD_PKA_1	436	442	PF00069	0.585
MOD_PKA_2	109	115	PF00069	0.460
MOD_PKA_2	17	23	PF00069	0.596
MOD_PKA_2	191	197	PF00069	0.437
MOD_PKA_2	392	398	PF00069	0.341
MOD_PKA_2	405	411	PF00069	0.175
MOD_PKA_2	436	442	PF00069	0.585
MOD_Plk_1	130	136	PF00069	0.542
MOD_Plk_1	196	202	PF00069	0.402
MOD_Plk_1	303	309	PF00069	0.446
MOD_Plk_1	339	345	PF00069	0.517
MOD_Plk_1	421	427	PF00069	0.417
MOD_Plk_1	75	81	PF00069	0.463
MOD_Plk_4	167	173	PF00069	0.428
MOD_Plk_4	293	299	PF00069	0.548
MOD_Plk_4	339	345	PF00069	0.517
MOD_ProDKin_1	116	122	PF00069	0.481
MOD_ProDKin_1	289	295	PF00069	0.542
MOD_ProDKin_1	335	341	PF00069	0.467
MOD_SUMO_rev_2	386	394	PF00179	0.365
TRG_ENDOCYTIC_2	385	388	PF00928	0.308
TRG_ENDOCYTIC_2	440	443	PF00928	0.475
TRG_ER_diArg_1	409	411	PF00400	0.429
TRG_NLS_MonoCore_2	99	104	PF00514	0.269
TRG_NLS_MonoExtN_4	100	105	PF00514	0.486
TRG_NLS_MonoExtN_4	433	440	PF00514	0.555

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3X3	Leptomonas seymouri	94%	100%
A0A0N1I6C2	Leptomonas seymouri	24%	100%
A0A0N1PB16	Leptomonas seymouri	23%	100%
A0A0S4IWG1	Bodo saltans	22%	91%
A0A0S4IWU9	Bodo saltans	25%	100%
A0A0S4J5T5	Bodo saltans	27%	82%
A0A0S4J6C2	Bodo saltans	68%	100%
A0A0S4JE21	Bodo saltans	23%	100%
A0A0S4JL38	Bodo saltans	24%	83%
A0A0S4KJ87	Bodo saltans	22%	74%
A0A1X0NQ96	Trypanosomatidae	23%	100%
A0A1X0NQI7	Trypanosomatidae	24%	100%
A0A1X0P0F0	Trypanosomatidae	25%	96%
A0A1X0P551	Trypanosomatidae	76%	100%
A0A3Q8IBR2	Leishmania donovani	26%	100%
A0A3R7KUH0	Trypanosoma rangeli	24%	100%
A0A3R7M2T7	Trypanosoma rangeli	24%	100%
A0A3R7N6M9	Trypanosoma rangeli	26%	85%
A0A3S7WR72	Leishmania donovani	23%	100%
A0A3S7X9Q7	Leishmania donovani	98%	100%
A0A422N1P8	Trypanosoma rangeli	74%	100%
A1CF18	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	22%	100%
A1CUD6	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	23%	95%
A1DP19	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	22%	100%
A2CEH0	Danio rerio	26%	91%
A2QP30	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	21%	100%
A4H666	Leishmania braziliensis	24%	100%
A4HDT7	Leishmania braziliensis	24%	85%
A4HGX7	Leishmania braziliensis	21%	100%
A4HN59	Leishmania braziliensis	95%	100%
A4HUJ0	Leishmania infantum	23%	100%
A4HZL2	Leishmania infantum	26%	100%
A4IBS6	Leishmania infantum	98%	100%
A6ZZZ8	Saccharomyces cerevisiae (strain YJM789)	22%	69%
A7S338	Nematostella vectensis	25%	100%
A8X8C6	Caenorhabditis briggsae	23%	100%
A9V790	Monosiga brevicollis	23%	100%
B0LSW3	Felis catus	24%	100%
B0XM00	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	22%	95%
B2VWG7	Pyrenophora tritici-repentis (strain Pt-1C-BFP)	20%	96%
B3MEY6	Drosophila ananassae	21%	100%
B3NPW0	Drosophila erecta	20%	100%
B3S4I5	Trichoplax adhaerens	23%	100%
B4GAJ1	Drosophila persimilis	21%	100%
B4HSL3	Drosophila sechellia	20%	100%
B4JWA1	Drosophila grimshawi	21%	100%
B4KT48	Drosophila mojavensis	21%	100%
B4LQ21	Drosophila virilis	21%	100%
B4P6P9	Drosophila yakuba	20%	100%
B4QHG6	Drosophila simulans	20%	100%
B5X3C4	Salmo salar	26%	100%
B5X3Z6	Salmo salar	24%	100%
B6GZD3	Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)	23%	96%
B6HP56	Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)	22%	97%
B6QC56	Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)	23%	97%
B7PS00	Ixodes scapularis	25%	100%
B8AP31	Oryza sativa subsp. indica	26%	100%
B8M0Q1	Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)	23%	97%
C0S902	Paracoccidioides brasiliensis (strain Pb03)	22%	93%
C1GB49	Paracoccidioides brasiliensis (strain Pb18)	22%	93%
C3XVT5	Branchiostoma floridae	21%	100%
C4JPW9	Uncinocarpus reesii (strain UAMH 1704)	21%	97%
C4JZS6	Uncinocarpus reesii (strain UAMH 1704)	20%	100%
C4Q0P6	Schistosoma mansoni	24%	100%
C5FWH1	Arthroderma otae (strain ATCC MYA-4605 / CBS 113480)	22%	96%
C5GVJ9	Ajellomyces dermatitidis (strain ER-3 / ATCC MYA-2586)	23%	94%
C5JD40	Blastomyces gilchristii (strain SLH14081)	23%	94%
C5PFX0	Coccidioides posadasii (strain C735)	23%	94%
C7Z6H2	Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4)	22%	99%
C9ZVL4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
C9ZW72	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	72%
C9ZYU6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	76%	100%
D3TLL6	Glossina morsitans morsitans	21%	100%
D3ZW91	Rattus norvegicus	26%	93%
D4AZ50	Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)	23%	96%
D4DG66	Trichophyton verrucosum (strain HKI 0517)	23%	96%
E8NHN2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	22%	100%
E9AFL2	Leishmania major	99%	100%
E9AN88	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9ATR6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	87%
F6ZT52	Xenopus tropicalis	25%	94%
G0SC29	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	26%	86%
O15736	Dictyostelium discoideum	23%	73%
O18640	Drosophila melanogaster	23%	100%
O22212	Arabidopsis thaliana	25%	80%
O24076	Medicago sativa	22%	100%
O24456	Arabidopsis thaliana	24%	100%
O42248	Danio rerio	22%	100%
O42249	Oreochromis niloticus	22%	100%
O43660	Homo sapiens	21%	86%
O60907	Homo sapiens	21%	77%
O74184	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
O74340	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	100%
O74855	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	88%
P16520	Homo sapiens	27%	100%
P17343	Caenorhabditis elegans	26%	100%
P23232	Loligo forbesii	27%	100%
P25382	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	86%
P25387	Chlamydomonas reinhardtii	26%	100%
P29829	Drosophila melanogaster	25%	100%
P33750	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	91%
P36130	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	22%	69%
P43033	Bos taurus	22%	100%
P43034	Homo sapiens	24%	100%
P46800	Dictyostelium discoideum	24%	100%
P49026	Nicotiana tabacum	24%	100%
P49027	Oryza sativa subsp. japonica	22%	100%
P49178	Zea mays	26%	100%
P52287	Rattus norvegicus	26%	100%
P61480	Rattus norvegicus	21%	100%
P62884	Leishmania infantum	22%	100%
P63004	Rattus norvegicus	24%	100%
P63005	Mus musculus	24%	100%
P63243	Bos taurus	23%	100%
P63244	Homo sapiens	23%	100%
P63245	Rattus norvegicus	23%	100%
P63246	Sus scrofa	23%	100%
P63247	Gallus gallus	23%	100%
P68040	Mus musculus	23%	100%
P79147	Canis lupus familiaris	26%	100%
P83774	Candida albicans (strain SC5314 / ATCC MYA-2876)	23%	100%
P93340	Nicotiana plumbaginifolia	23%	100%
P93397	Nicotiana tabacum	24%	100%
P93398	Nicotiana tabacum	24%	100%
P93563	Solanum tuberosum	24%	100%
Q00664	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	22%	100%
Q01369	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	22%	100%
Q0D0X6	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	21%	100%
Q0P593	Bos taurus	21%	100%
Q10281	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
Q12417	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	98%
Q17963	Caenorhabditis elegans	23%	100%
Q17N69	Aedes aegypti	22%	100%
Q19124	Caenorhabditis elegans	23%	84%
Q1LV15	Danio rerio	22%	100%
Q229Z6	Tetrahymena thermophila (strain SB210)	22%	70%
Q25189	Hydra vulgaris	23%	100%
Q25306	Leishmania major	22%	100%
Q28I85	Xenopus tropicalis	27%	100%
Q291L9	Drosophila pseudoobscura pseudoobscura	21%	100%
Q29HG9	Drosophila pseudoobscura pseudoobscura	24%	100%
Q2KID6	Bos taurus	21%	87%
Q2TBP4	Bos taurus	26%	100%
Q2TZG4	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	24%	73%
Q2UA71	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	22%	100%
Q39190	Arabidopsis thaliana	24%	93%
Q39336	Brassica napus	24%	100%
Q39836	Glycine max	24%	100%
Q3MKM6	Arabidopsis thaliana	24%	93%
Q3Y8L7	Chlamydomonas reinhardtii	24%	100%
Q40507	Nicotiana tabacum	24%	100%
Q40687	Oryza sativa subsp. japonica	26%	100%
Q42384	Arabidopsis thaliana	24%	91%
Q4ICM0	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	23%	97%
Q4P9P9	Ustilago maydis (strain 521 / FGSC 9021)	22%	98%
Q4Q0T1	Leishmania major	24%	100%
Q4Q7Y7	Leishmania major	22%	100%
Q4QCL0	Leishmania major	26%	100%
Q4QHD6	Leishmania major	24%	100%
Q4R7Y4	Macaca fascicularis	23%	100%
Q4R8E7	Macaca fascicularis	21%	100%
Q4R8H1	Macaca fascicularis	21%	78%
Q4RJN5	Tetraodon nigroviridis	25%	100%
Q4V7Y7	Xenopus laevis	22%	68%
Q4V7Z1	Xenopus laevis	25%	95%
Q4V8C4	Rattus norvegicus	23%	100%
Q4WEI5	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	23%	100%
Q4WLM7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	22%	95%
Q4WT34	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	20%	98%
Q54KL5	Dictyostelium discoideum	21%	100%
Q58D20	Bos taurus	24%	91%
Q5BK30	Rattus norvegicus	21%	100%
Q5FVN8	Rattus norvegicus	23%	93%
Q5FWQ6	Xenopus laevis	20%	100%
Q5GIS3	Pinctada fucata	26%	100%
Q5IS43	Pan troglodytes	24%	100%
Q5R4T8	Pongo abelii	37%	100%
Q5RE95	Pongo abelii	23%	100%
Q5REG7	Pongo abelii	24%	100%
Q5RFF8	Pongo abelii	25%	92%
Q5ZIU8	Gallus gallus	23%	68%
Q5ZLK1	Gallus gallus	37%	100%
Q61011	Mus musculus	26%	100%
Q61ZF6	Caenorhabditis briggsae	26%	100%
Q6BU94	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	21%	100%
Q6CKE8	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	24%	100%
Q6FJZ9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	23%	100%
Q6FXI8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	22%	100%
Q6GPC6	Xenopus laevis	22%	85%
Q6L4F8	Oryza sativa subsp. japonica	23%	100%
Q6NVM2	Xenopus tropicalis	22%	68%
Q6NVS5	Xenopus tropicalis	37%	100%
Q6NX08	Danio rerio	24%	100%
Q6NZH4	Xenopus tropicalis	23%	100%
Q6P2Y2	Xenopus tropicalis	20%	100%
Q6P5M2	Danio rerio	25%	100%
Q6PAC3	Mus musculus	38%	100%
Q6S7B0	Arabidopsis thaliana	23%	66%
Q6ZMY6	Homo sapiens	24%	94%
Q75BY3	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	24%	100%
Q76LS6	Leishmania donovani	22%	100%
Q7KNS3	Drosophila melanogaster	20%	100%
Q7KWL3	Dictyostelium discoideum	37%	100%
Q7QJ33	Anopheles gambiae	23%	100%
Q7S7N3	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	21%	100%
Q7SZM9	Xenopus laevis	22%	86%
Q7T394	Danio rerio	26%	100%
Q7ZVF0	Danio rerio	24%	100%
Q7ZXK9	Xenopus laevis	23%	93%
Q7ZYQ6	Xenopus laevis	37%	100%
Q803D2	Danio rerio	25%	100%
Q803X4	Danio rerio	38%	100%
Q86VZ2	Homo sapiens	23%	100%
Q8BHJ5	Mus musculus	22%	86%
Q8HXX0	Macaca fascicularis	22%	100%
Q8I0F4	Dictyostelium discoideum	23%	100%
Q8JZX3	Mus musculus	24%	100%
Q8N136	Homo sapiens	21%	100%
Q8NBT0	Homo sapiens	26%	100%
Q8TC44	Homo sapiens	24%	93%
Q8VEJ4	Mus musculus	24%	92%
Q90ZL4	Xenopus laevis	23%	100%
Q922V4	Mus musculus	21%	87%
Q9BQ87	Homo sapiens	23%	85%
Q9BZK7	Homo sapiens	22%	86%
Q9C4Z6	Arabidopsis thaliana	21%	100%
Q9D7H2	Mus musculus	23%	100%
Q9FLX9	Arabidopsis thaliana	24%	94%
Q9FN19	Arabidopsis thaliana	24%	72%
Q9GL51	Sus scrofa	24%	100%
Q9JJA4	Mus musculus	22%	100%
Q9LV28	Arabidopsis thaliana	24%	100%
Q9NDC9	Caenorhabditis elegans	23%	100%
Q9NV06	Homo sapiens	37%	100%
Q9NVX2	Homo sapiens	25%	92%
Q9NYS7	Homo sapiens	22%	100%
Q9PTR5	Gallus gallus	24%	100%
Q9QXE7	Mus musculus	23%	84%
Q9VPR4	Drosophila melanogaster	23%	91%
Q9W328	Drosophila melanogaster	24%	100%
Q9WUC8	Rattus norvegicus	21%	86%
V5B6G4	Trypanosoma cruzi	23%	100%
V5BDQ2	Trypanosoma cruzi	24%	100%
V5BEB2	Trypanosoma cruzi	23%	82%
V5BP59	Trypanosoma cruzi	23%	100%
V5DUL4	Trypanosoma cruzi	74%	100%