LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B6P4_LEIMU
TriTrypDb:
LmxM.34.3650
Length:
860

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6P4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6P4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 244 248 PF00656 0.678
CLV_C14_Caspase3-7 36 40 PF00656 0.683
CLV_C14_Caspase3-7 628 632 PF00656 0.709
CLV_C14_Caspase3-7 704 708 PF00656 0.824
CLV_NRD_NRD_1 121 123 PF00675 0.476
CLV_NRD_NRD_1 187 189 PF00675 0.611
CLV_NRD_NRD_1 324 326 PF00675 0.825
CLV_NRD_NRD_1 370 372 PF00675 0.671
CLV_NRD_NRD_1 519 521 PF00675 0.846
CLV_NRD_NRD_1 576 578 PF00675 0.593
CLV_NRD_NRD_1 614 616 PF00675 0.821
CLV_NRD_NRD_1 655 657 PF00675 0.741
CLV_NRD_NRD_1 759 761 PF00675 0.579
CLV_PCSK_KEX2_1 121 123 PF00082 0.476
CLV_PCSK_KEX2_1 187 189 PF00082 0.611
CLV_PCSK_KEX2_1 324 326 PF00082 0.683
CLV_PCSK_KEX2_1 370 372 PF00082 0.661
CLV_PCSK_KEX2_1 519 521 PF00082 0.846
CLV_PCSK_KEX2_1 576 578 PF00082 0.593
CLV_PCSK_KEX2_1 614 616 PF00082 0.821
CLV_PCSK_KEX2_1 655 657 PF00082 0.747
CLV_PCSK_KEX2_1 759 761 PF00082 0.528
CLV_PCSK_KEX2_1 850 852 PF00082 0.714
CLV_PCSK_PC1ET2_1 850 852 PF00082 0.714
CLV_PCSK_PC7_1 651 657 PF00082 0.798
CLV_PCSK_SKI1_1 121 125 PF00082 0.474
CLV_PCSK_SKI1_1 187 191 PF00082 0.728
CLV_PCSK_SKI1_1 232 236 PF00082 0.700
CLV_PCSK_SKI1_1 520 524 PF00082 0.835
DEG_APCC_DBOX_1 120 128 PF00400 0.477
DEG_COP1_1 473 480 PF00400 0.657
DEG_SPOP_SBC_1 333 337 PF00917 0.686
DEG_SPOP_SBC_1 443 447 PF00917 0.560
DEG_SPOP_SBC_1 527 531 PF00917 0.615
DEG_SPOP_SBC_1 558 562 PF00917 0.809
DOC_CKS1_1 191 196 PF01111 0.804
DOC_CKS1_1 578 583 PF01111 0.516
DOC_CYCLIN_RxL_1 102 113 PF00134 0.677
DOC_CYCLIN_RxL_1 185 196 PF00134 0.732
DOC_CYCLIN_yCln2_LP_2 362 368 PF00134 0.822
DOC_CYCLIN_yCln2_LP_2 468 471 PF00134 0.632
DOC_CYCLIN_yCln2_LP_2 692 698 PF00134 0.762
DOC_MAPK_gen_1 759 767 PF00069 0.499
DOC_MAPK_MEF2A_6 760 769 PF00069 0.486
DOC_MAPK_MEF2A_6 799 808 PF00069 0.765
DOC_PP1_RVXF_1 186 193 PF00149 0.735
DOC_PP2B_LxvP_1 109 112 PF13499 0.665
DOC_PP2B_LxvP_1 169 172 PF13499 0.648
DOC_PP2B_LxvP_1 305 308 PF13499 0.567
DOC_PP2B_LxvP_1 362 365 PF13499 0.670
DOC_PP2B_LxvP_1 468 471 PF13499 0.682
DOC_PP4_FxxP_1 98 101 PF00568 0.695
DOC_USP7_MATH_1 144 148 PF00917 0.765
DOC_USP7_MATH_1 197 201 PF00917 0.526
DOC_USP7_MATH_1 366 370 PF00917 0.628
DOC_USP7_MATH_1 374 378 PF00917 0.741
DOC_USP7_MATH_1 393 397 PF00917 0.664
DOC_USP7_MATH_1 423 427 PF00917 0.696
DOC_USP7_MATH_1 443 447 PF00917 0.660
DOC_USP7_MATH_1 494 498 PF00917 0.634
DOC_USP7_MATH_1 527 531 PF00917 0.815
DOC_USP7_MATH_1 537 541 PF00917 0.652
DOC_USP7_MATH_1 566 570 PF00917 0.721
DOC_USP7_MATH_1 619 623 PF00917 0.695
DOC_USP7_MATH_1 664 668 PF00917 0.658
DOC_USP7_MATH_1 701 705 PF00917 0.807
DOC_USP7_MATH_1 75 79 PF00917 0.615
DOC_USP7_MATH_1 751 755 PF00917 0.789
DOC_USP7_MATH_1 836 840 PF00917 0.707
DOC_WW_Pin1_4 190 195 PF00397 0.806
DOC_WW_Pin1_4 213 218 PF00397 0.803
DOC_WW_Pin1_4 344 349 PF00397 0.690
DOC_WW_Pin1_4 372 377 PF00397 0.592
DOC_WW_Pin1_4 415 420 PF00397 0.821
DOC_WW_Pin1_4 511 516 PF00397 0.732
DOC_WW_Pin1_4 52 57 PF00397 0.726
DOC_WW_Pin1_4 520 525 PF00397 0.681
DOC_WW_Pin1_4 544 549 PF00397 0.650
DOC_WW_Pin1_4 570 575 PF00397 0.829
DOC_WW_Pin1_4 577 582 PF00397 0.684
DOC_WW_Pin1_4 594 599 PF00397 0.590
DOC_WW_Pin1_4 607 612 PF00397 0.628
DOC_WW_Pin1_4 632 637 PF00397 0.853
DOC_WW_Pin1_4 697 702 PF00397 0.760
LIG_14-3-3_CanoR_1 126 133 PF00244 0.707
LIG_14-3-3_CanoR_1 204 208 PF00244 0.749
LIG_14-3-3_CanoR_1 229 235 PF00244 0.561
LIG_14-3-3_CanoR_1 332 341 PF00244 0.839
LIG_14-3-3_CanoR_1 493 501 PF00244 0.667
LIG_14-3-3_CanoR_1 614 618 PF00244 0.548
LIG_14-3-3_CanoR_1 62 68 PF00244 0.742
LIG_14-3-3_CanoR_1 649 654 PF00244 0.761
LIG_14-3-3_CanoR_1 655 663 PF00244 0.731
LIG_14-3-3_CanoR_1 697 701 PF00244 0.748
LIG_14-3-3_CanoR_1 851 857 PF00244 0.715
LIG_Actin_WH2_2 120 138 PF00022 0.625
LIG_Actin_WH2_2 214 231 PF00022 0.549
LIG_BIR_III_4 618 622 PF00653 0.565
LIG_BRCT_BRCA1_1 401 405 PF00533 0.544
LIG_Clathr_ClatBox_1 80 84 PF01394 0.710
LIG_CSL_BTD_1 463 466 PF09270 0.823
LIG_FHA_1 101 107 PF00498 0.692
LIG_FHA_1 12 18 PF00498 0.568
LIG_FHA_1 249 255 PF00498 0.555
LIG_FHA_1 291 297 PF00498 0.586
LIG_FHA_1 334 340 PF00498 0.840
LIG_FHA_1 350 356 PF00498 0.572
LIG_FHA_1 36 42 PF00498 0.735
LIG_FHA_1 390 396 PF00498 0.672
LIG_FHA_1 401 407 PF00498 0.651
LIG_FHA_1 472 478 PF00498 0.806
LIG_FHA_1 53 59 PF00498 0.516
LIG_FHA_1 595 601 PF00498 0.769
LIG_FHA_2 242 248 PF00498 0.560
LIG_FHA_2 527 533 PF00498 0.543
LIG_FHA_2 719 725 PF00498 0.686
LIG_FHA_2 790 796 PF00498 0.464
LIG_LIR_Apic_2 96 101 PF02991 0.694
LIG_LIR_Gen_1 18 27 PF02991 0.636
LIG_LIR_Gen_1 716 727 PF02991 0.676
LIG_LIR_Gen_1 73 81 PF02991 0.520
LIG_LIR_Nem_3 103 107 PF02991 0.691
LIG_LIR_Nem_3 118 123 PF02991 0.453
LIG_LIR_Nem_3 18 22 PF02991 0.550
LIG_LIR_Nem_3 46 50 PF02991 0.728
LIG_LIR_Nem_3 550 556 PF02991 0.801
LIG_LIR_Nem_3 716 722 PF02991 0.674
LIG_LIR_Nem_3 73 77 PF02991 0.528
LIG_LIR_Nem_3 814 819 PF02991 0.720
LIG_LYPXL_yS_3 47 50 PF13949 0.726
LIG_MYND_1 466 470 PF01753 0.637
LIG_MYND_1 598 602 PF01753 0.620
LIG_NRBOX 12 18 PF00104 0.493
LIG_NRBOX 377 383 PF00104 0.804
LIG_PTAP_UEV_1 307 312 PF05743 0.558
LIG_SH2_CRK 104 108 PF00017 0.685
LIG_SH2_CRK 606 610 PF00017 0.811
LIG_SH2_CRK 74 78 PF00017 0.727
LIG_SH2_NCK_1 74 78 PF00017 0.727
LIG_SH2_PTP2 717 720 PF00017 0.668
LIG_SH2_SRC 553 556 PF00017 0.815
LIG_SH2_STAT5 108 111 PF00017 0.657
LIG_SH2_STAT5 34 37 PF00017 0.747
LIG_SH2_STAT5 588 591 PF00017 0.780
LIG_SH2_STAT5 669 672 PF00017 0.802
LIG_SH2_STAT5 717 720 PF00017 0.668
LIG_SH2_STAT5 785 788 PF00017 0.688
LIG_SH2_STAT5 845 848 PF00017 0.700
LIG_SH2_STAT5 852 855 PF00017 0.596
LIG_SH3_2 315 320 PF14604 0.687
LIG_SH3_3 18 24 PF00018 0.704
LIG_SH3_3 191 197 PF00018 0.671
LIG_SH3_3 211 217 PF00018 0.491
LIG_SH3_3 296 302 PF00018 0.747
LIG_SH3_3 305 311 PF00018 0.724
LIG_SH3_3 312 318 PF00018 0.658
LIG_SH3_3 338 344 PF00018 0.834
LIG_SH3_3 345 351 PF00018 0.706
LIG_SH3_3 370 376 PF00018 0.681
LIG_SH3_3 519 525 PF00018 0.556
LIG_SH3_3 575 581 PF00018 0.533
LIG_SH3_3 673 679 PF00018 0.645
LIG_SH3_3 695 701 PF00018 0.748
LIG_SH3_3 725 731 PF00018 0.656
LIG_SUMO_SIM_anti_2 802 809 PF11976 0.762
LIG_SUMO_SIM_par_1 762 768 PF11976 0.484
LIG_SUMO_SIM_par_1 802 809 PF11976 0.487
LIG_TRAF2_1 70 73 PF00917 0.537
LIG_TYR_ITIM 604 609 PF00017 0.805
LIG_WRC_WIRS_1 281 286 PF05994 0.551
LIG_WRC_WIRS_1 771 776 PF05994 0.682
LIG_WW_3 508 512 PF00397 0.818
MOD_CDC14_SPxK_1 573 576 PF00782 0.599
MOD_CDK_SPK_2 598 603 PF00069 0.774
MOD_CDK_SPK_2 632 637 PF00069 0.578
MOD_CDK_SPK_2 697 702 PF00069 0.760
MOD_CDK_SPxK_1 570 576 PF00069 0.605
MOD_CDK_SPxxK_3 570 577 PF00069 0.829
MOD_CDK_SPxxK_3 607 614 PF00069 0.809
MOD_CK1_1 174 180 PF00069 0.611
MOD_CK1_1 216 222 PF00069 0.560
MOD_CK1_1 245 251 PF00069 0.558
MOD_CK1_1 260 266 PF00069 0.492
MOD_CK1_1 280 286 PF00069 0.625
MOD_CK1_1 290 296 PF00069 0.621
MOD_CK1_1 33 39 PF00069 0.693
MOD_CK1_1 337 343 PF00069 0.781
MOD_CK1_1 347 353 PF00069 0.700
MOD_CK1_1 394 400 PF00069 0.722
MOD_CK1_1 418 424 PF00069 0.679
MOD_CK1_1 544 550 PF00069 0.754
MOD_CK1_1 569 575 PF00069 0.831
MOD_CK1_1 63 69 PF00069 0.738
MOD_CK1_1 632 638 PF00069 0.851
MOD_CK1_1 659 665 PF00069 0.808
MOD_CK1_1 700 706 PF00069 0.650
MOD_CK2_1 216 222 PF00069 0.835
MOD_CK2_1 526 532 PF00069 0.544
MOD_CK2_1 718 724 PF00069 0.682
MOD_CK2_1 789 795 PF00069 0.444
MOD_Cter_Amidation 322 325 PF01082 0.837
MOD_Cter_Amidation 653 656 PF01082 0.794
MOD_DYRK1A_RPxSP_1 520 524 PF00069 0.560
MOD_DYRK1A_RPxSP_1 577 581 PF00069 0.524
MOD_DYRK1A_RPxSP_1 607 611 PF00069 0.684
MOD_DYRK1A_RPxSP_1 697 701 PF00069 0.748
MOD_GlcNHglycan 112 115 PF01048 0.649
MOD_GlcNHglycan 153 156 PF01048 0.739
MOD_GlcNHglycan 218 221 PF01048 0.844
MOD_GlcNHglycan 289 292 PF01048 0.653
MOD_GlcNHglycan 321 324 PF01048 0.607
MOD_GlcNHglycan 336 339 PF01048 0.598
MOD_GlcNHglycan 357 360 PF01048 0.817
MOD_GlcNHglycan 406 409 PF01048 0.621
MOD_GlcNHglycan 425 428 PF01048 0.691
MOD_GlcNHglycan 446 449 PF01048 0.840
MOD_GlcNHglycan 568 571 PF01048 0.588
MOD_GlcNHglycan 582 585 PF01048 0.561
MOD_GlcNHglycan 63 66 PF01048 0.741
MOD_GlcNHglycan 631 634 PF01048 0.856
MOD_GlcNHglycan 637 640 PF01048 0.737
MOD_GlcNHglycan 67 70 PF01048 0.683
MOD_GlcNHglycan 703 706 PF01048 0.697
MOD_GlcNHglycan 753 756 PF01048 0.783
MOD_GlcNHglycan 761 764 PF01048 0.646
MOD_GlcNHglycan 808 811 PF01048 0.467
MOD_GSK3_1 174 181 PF00069 0.739
MOD_GSK3_1 193 200 PF00069 0.558
MOD_GSK3_1 241 248 PF00069 0.680
MOD_GSK3_1 276 283 PF00069 0.794
MOD_GSK3_1 286 293 PF00069 0.628
MOD_GSK3_1 29 36 PF00069 0.737
MOD_GSK3_1 306 313 PF00069 0.732
MOD_GSK3_1 333 340 PF00069 0.775
MOD_GSK3_1 389 396 PF00069 0.656
MOD_GSK3_1 400 407 PF00069 0.562
MOD_GSK3_1 511 518 PF00069 0.847
MOD_GSK3_1 537 544 PF00069 0.741
MOD_GSK3_1 557 564 PF00069 0.552
MOD_GSK3_1 566 573 PF00069 0.689
MOD_GSK3_1 57 64 PF00069 0.736
MOD_GSK3_1 594 601 PF00069 0.769
MOD_GSK3_1 619 626 PF00069 0.852
MOD_GSK3_1 631 638 PF00069 0.655
MOD_GSK3_1 696 703 PF00069 0.615
MOD_GSK3_1 759 766 PF00069 0.782
MOD_N-GLC_1 286 291 PF02516 0.543
MOD_N-GLC_1 355 360 PF02516 0.836
MOD_N-GLC_1 383 388 PF02516 0.531
MOD_N-GLC_2 736 738 PF02516 0.542
MOD_NEK2_1 107 112 PF00069 0.612
MOD_NEK2_1 135 140 PF00069 0.653
MOD_NEK2_1 17 22 PF00069 0.649
MOD_NEK2_1 228 233 PF00069 0.610
MOD_NEK2_1 30 35 PF00069 0.632
MOD_NEK2_1 339 344 PF00069 0.834
MOD_NEK2_1 444 449 PF00069 0.688
MOD_NEK2_1 605 610 PF00069 0.685
MOD_NEK2_1 806 811 PF00069 0.481
MOD_NEK2_1 834 839 PF00069 0.545
MOD_NEK2_2 852 857 PF00069 0.713
MOD_PIKK_1 174 180 PF00454 0.734
MOD_PIKK_1 484 490 PF00454 0.675
MOD_PK_1 391 397 PF00069 0.677
MOD_PKA_1 759 765 PF00069 0.514
MOD_PKA_2 125 131 PF00069 0.593
MOD_PKA_2 135 141 PF00069 0.626
MOD_PKA_2 203 209 PF00069 0.828
MOD_PKA_2 228 234 PF00069 0.818
MOD_PKA_2 245 251 PF00069 0.557
MOD_PKA_2 331 337 PF00069 0.704
MOD_PKA_2 457 463 PF00069 0.558
MOD_PKA_2 61 67 PF00069 0.743
MOD_PKA_2 613 619 PF00069 0.606
MOD_PKA_2 696 702 PF00069 0.757
MOD_PKA_2 759 765 PF00069 0.514
MOD_PKA_2 795 801 PF00069 0.756
MOD_PKB_1 511 519 PF00069 0.747
MOD_PKB_1 627 635 PF00069 0.857
MOD_PKB_1 815 823 PF00069 0.697
MOD_Plk_1 17 23 PF00069 0.673
MOD_Plk_1 260 266 PF00069 0.529
MOD_Plk_1 30 36 PF00069 0.583
MOD_Plk_1 558 564 PF00069 0.811
MOD_Plk_1 6 12 PF00069 0.585
MOD_Plk_4 165 171 PF00069 0.634
MOD_Plk_4 252 258 PF00069 0.545
MOD_Plk_4 54 60 PF00069 0.728
MOD_Plk_4 541 547 PF00069 0.527
MOD_Plk_4 680 686 PF00069 0.718
MOD_Plk_4 713 719 PF00069 0.698
MOD_Plk_4 76 82 PF00069 0.714
MOD_ProDKin_1 190 196 PF00069 0.805
MOD_ProDKin_1 213 219 PF00069 0.806
MOD_ProDKin_1 344 350 PF00069 0.692
MOD_ProDKin_1 372 378 PF00069 0.594
MOD_ProDKin_1 415 421 PF00069 0.822
MOD_ProDKin_1 511 517 PF00069 0.733
MOD_ProDKin_1 52 58 PF00069 0.725
MOD_ProDKin_1 520 526 PF00069 0.682
MOD_ProDKin_1 544 550 PF00069 0.646
MOD_ProDKin_1 570 576 PF00069 0.830
MOD_ProDKin_1 577 583 PF00069 0.682
MOD_ProDKin_1 594 600 PF00069 0.591
MOD_ProDKin_1 607 613 PF00069 0.628
MOD_ProDKin_1 632 638 PF00069 0.851
MOD_ProDKin_1 697 703 PF00069 0.769
MOD_SUMO_rev_2 616 622 PF00179 0.561
TRG_DiLeu_BaEn_1 740 745 PF01217 0.583
TRG_DiLeu_BaEn_1 802 807 PF01217 0.775
TRG_DiLeu_BaEn_4 740 746 PF01217 0.587
TRG_DiLeu_BaLyEn_6 102 107 PF01217 0.564
TRG_DiLeu_BaLyEn_6 677 682 PF01217 0.771
TRG_DiLeu_BaLyEn_6 801 806 PF01217 0.777
TRG_ENDOCYTIC_2 104 107 PF00928 0.689
TRG_ENDOCYTIC_2 47 50 PF00928 0.726
TRG_ENDOCYTIC_2 553 556 PF00928 0.815
TRG_ENDOCYTIC_2 606 609 PF00928 0.812
TRG_ENDOCYTIC_2 717 720 PF00928 0.668
TRG_ENDOCYTIC_2 74 77 PF00928 0.726
TRG_ER_diArg_1 120 122 PF00400 0.465
TRG_ER_diArg_1 186 188 PF00400 0.612
TRG_ER_diArg_1 207 210 PF00400 0.709
TRG_ER_diArg_1 370 372 PF00400 0.666
TRG_ER_diArg_1 510 513 PF00400 0.691
TRG_ER_diArg_1 576 578 PF00400 0.591
TRG_ER_diArg_1 613 615 PF00400 0.814
TRG_ER_diArg_1 91 94 PF00400 0.692
TRG_Pf-PMV_PEXEL_1 325 329 PF00026 0.687

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IIL4 Leishmania donovani 81% 100%
A4IBQ4 Leishmania infantum 79% 100%
E9AFI9 Leishmania major 83% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS