NET domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B6P3_LEIMU

TriTrypDb:

LmxM.34.3640

Length:

201

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6P3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6P3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	108	112	PF00656	0.582
CLV_C14_Caspase3-7	6	10	PF00656	0.440
CLV_NRD_NRD_1	126	128	PF00675	0.458
CLV_NRD_NRD_1	152	154	PF00675	0.463
CLV_NRD_NRD_1	195	197	PF00675	0.622
CLV_PCSK_KEX2_1	126	128	PF00082	0.485
CLV_PCSK_KEX2_1	152	154	PF00082	0.463
CLV_PCSK_KEX2_1	195	197	PF00082	0.623
DOC_CKS1_1	191	196	PF01111	0.460
DOC_PP2B_LxvP_1	113	116	PF13499	0.560
DOC_USP7_MATH_1	49	53	PF00917	0.652
DOC_WW_Pin1_4	140	145	PF00397	0.567
DOC_WW_Pin1_4	190	195	PF00397	0.459
LIG_14-3-3_CanoR_1	105	111	PF00244	0.600
LIG_14-3-3_CanoR_1	152	162	PF00244	0.705
LIG_14-3-3_CanoR_1	18	23	PF00244	0.444
LIG_14-3-3_CanoR_1	25	30	PF00244	0.525
LIG_14-3-3_CanoR_1	38	47	PF00244	0.435
LIG_BIR_II_1	1	5	PF00653	0.618
LIG_EH1_1	16	24	PF00400	0.431
LIG_eIF4E_1	17	23	PF01652	0.447
LIG_FHA_1	26	32	PF00498	0.540
LIG_FHA_1	3	9	PF00498	0.505
LIG_FHA_1	39	45	PF00498	0.392
LIG_FHA_1	83	89	PF00498	0.677
LIG_LIR_Gen_1	45	55	PF02991	0.442
LIG_PTAP_UEV_1	143	148	PF05743	0.516
LIG_SH3_2	191	196	PF14604	0.460
LIG_SH3_3	141	147	PF00018	0.543
LIG_SH3_3	188	194	PF00018	0.458
LIG_SUMO_SIM_anti_2	164	176	PF11976	0.427
LIG_SUMO_SIM_par_1	134	140	PF11976	0.383
MOD_CDK_SPK_2	190	195	PF00069	0.459
MOD_CDK_SPxK_1	190	196	PF00069	0.460
MOD_CK1_1	140	146	PF00069	0.518
MOD_CK1_1	165	171	PF00069	0.523
MOD_CK1_1	2	8	PF00069	0.602
MOD_CK1_1	68	74	PF00069	0.777
MOD_CK2_1	69	75	PF00069	0.656
MOD_Cter_Amidation	150	153	PF01082	0.460
MOD_GlcNHglycan	139	142	PF01048	0.593
MOD_GlcNHglycan	144	147	PF01048	0.602
MOD_GlcNHglycan	65	68	PF01048	0.679
MOD_GlcNHglycan	70	74	PF01048	0.700
MOD_GSK3_1	161	168	PF00069	0.633
MOD_GSK3_1	33	40	PF00069	0.603
MOD_GSK3_1	65	72	PF00069	0.701
MOD_GSK3_1	82	89	PF00069	0.649
MOD_NEK2_1	37	42	PF00069	0.630
MOD_NEK2_1	86	91	PF00069	0.468
MOD_NEK2_2	33	38	PF00069	0.379
MOD_PKA_2	2	8	PF00069	0.643
MOD_PKA_2	37	43	PF00069	0.557
MOD_Plk_4	18	24	PF00069	0.432
MOD_Plk_4	86	92	PF00069	0.532
MOD_ProDKin_1	140	146	PF00069	0.572
MOD_ProDKin_1	190	196	PF00069	0.460
TRG_ER_diArg_1	194	196	PF00400	0.627
TRG_Pf-PMV_PEXEL_1	195	199	PF00026	0.682

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBI1	Leptomonas seymouri	45%	91%
A0A1X0P5H7	Trypanosomatidae	33%	100%
A0A3Q8IMQ4	Leishmania donovani	87%	99%
A0A422NR35	Trypanosoma rangeli	35%	100%
A4HN35	Leishmania braziliensis	70%	100%
A4IBQ3	Leishmania infantum	86%	99%
C9ZYX2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	79%
E9AFI8	Leishmania major	88%	100%
V5BD49	Trypanosoma cruzi	32%	100%