Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B6N2_LEIMU

TriTrypDb:

LmxM.34.3530

Length:

426

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6N2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6N2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	195	199	PF00656	0.669
CLV_C14_Caspase3-7	338	342	PF00656	0.522
CLV_C14_Caspase3-7	389	393	PF00656	0.573
CLV_C14_Caspase3-7	394	398	PF00656	0.522
CLV_PCSK_SKI1_1	173	177	PF00082	0.600
DOC_CYCLIN_yCln2_LP_2	413	419	PF00134	0.601
DOC_MAPK_gen_1	214	223	PF00069	0.473
DOC_MAPK_MEF2A_6	203	212	PF00069	0.534
DOC_MAPK_MEF2A_6	214	223	PF00069	0.517
DOC_PP1_RVXF_1	185	191	PF00149	0.644
DOC_PP1_SILK_1	297	302	PF00149	0.591
DOC_PP2B_LxvP_1	351	354	PF13499	0.473
DOC_PP4_FxxP_1	94	97	PF00568	0.525
DOC_USP7_MATH_1	136	140	PF00917	0.654
DOC_USP7_MATH_1	14	18	PF00917	0.488
DOC_USP7_MATH_1	229	233	PF00917	0.433
DOC_USP7_MATH_1	257	261	PF00917	0.604
DOC_USP7_MATH_1	97	101	PF00917	0.518
DOC_USP7_UBL2_3	108	112	PF12436	0.684
DOC_WW_Pin1_4	262	267	PF00397	0.677
LIG_14-3-3_CanoR_1	388	396	PF00244	0.574
LIG_14-3-3_CanoR_1	50	59	PF00244	0.523
LIG_Actin_WH2_2	174	191	PF00022	0.537
LIG_Actin_WH2_2	288	303	PF00022	0.594
LIG_APCC_ABBA_1	167	172	PF00400	0.587
LIG_BIR_II_1	1	5	PF00653	0.581
LIG_BIR_III_4	122	126	PF00653	0.698
LIG_CaM_NSCaTE_8	296	303	PF13499	0.590
LIG_deltaCOP1_diTrp_1	143	152	PF00928	0.587
LIG_deltaCOP1_diTrp_1	376	380	PF00928	0.615
LIG_EH1_1	45	53	PF00400	0.441
LIG_eIF4E_1	278	284	PF01652	0.578
LIG_EVH1_1	318	322	PF00568	0.567
LIG_FHA_1	22	28	PF00498	0.583
LIG_FHA_1	43	49	PF00498	0.735
LIG_FHA_1	82	88	PF00498	0.540
LIG_FHA_2	135	141	PF00498	0.719
LIG_FHA_2	152	158	PF00498	0.460
LIG_FHA_2	270	276	PF00498	0.609
LIG_FHA_2	347	353	PF00498	0.622
LIG_FHA_2	387	393	PF00498	0.633
LIG_GBD_Chelix_1	180	188	PF00786	0.577
LIG_LIR_Apic_2	68	74	PF02991	0.642
LIG_LIR_Apic_2	92	97	PF02991	0.522
LIG_LIR_Gen_1	243	254	PF02991	0.536
LIG_LIR_Gen_1	293	303	PF02991	0.597
LIG_LIR_Gen_1	377	386	PF02991	0.694
LIG_LIR_Gen_1	407	417	PF02991	0.517
LIG_LIR_Nem_3	243	249	PF02991	0.701
LIG_LIR_Nem_3	275	281	PF02991	0.613
LIG_LIR_Nem_3	293	299	PF02991	0.481
LIG_LIR_Nem_3	377	383	PF02991	0.697
LIG_LIR_Nem_3	407	413	PF02991	0.520
LIG_LIR_Nem_3	418	424	PF02991	0.526
LIG_NRBOX	399	405	PF00104	0.492
LIG_Rb_LxCxE_1	330	352	PF01857	0.657
LIG_Rb_pABgroove_1	240	248	PF01858	0.540
LIG_SH2_NCK_1	71	75	PF00017	0.569
LIG_SH2_SRC	356	359	PF00017	0.582
LIG_SH2_SRC	71	74	PF00017	0.643
LIG_SH2_STAP1	356	360	PF00017	0.576
LIG_SH2_STAP1	417	421	PF00017	0.511
LIG_SH2_STAT5	287	290	PF00017	0.532
LIG_SH2_STAT5	35	38	PF00017	0.544
LIG_SH2_STAT5	417	420	PF00017	0.507
LIG_SH3_3	216	222	PF00018	0.519
LIG_SH3_3	247	253	PF00018	0.544
LIG_SH3_3	313	319	PF00018	0.584
LIG_SUMO_SIM_anti_2	381	387	PF11976	0.605
LIG_TRAF2_1	272	275	PF00917	0.607
LIG_TRAF2_1	7	10	PF00917	0.490
LIG_UBA3_1	245	251	PF00899	0.607
LIG_WRC_WIRS_1	328	333	PF05994	0.525
LIG_WRC_WIRS_1	90	95	PF05994	0.623
LIG_WW_1	353	356	PF00397	0.448
LIG_WW_2	319	322	PF00397	0.564
MOD_CK1_1	107	113	PF00069	0.693
MOD_CK1_1	17	23	PF00069	0.488
MOD_CK1_1	261	267	PF00069	0.674
MOD_CK1_1	362	368	PF00069	0.557
MOD_CK1_1	398	404	PF00069	0.490
MOD_CK1_1	99	105	PF00069	0.499
MOD_CK2_1	269	275	PF00069	0.622
MOD_CK2_1	333	339	PF00069	0.729
MOD_CK2_1	346	352	PF00069	0.527
MOD_CK2_1	4	10	PF00069	0.499
MOD_CK2_1	50	56	PF00069	0.584
MOD_GlcNHglycan	126	130	PF01048	0.627
MOD_GlcNHglycan	19	22	PF01048	0.550
MOD_GlcNHglycan	227	230	PF01048	0.414
MOD_GlcNHglycan	24	27	PF01048	0.509
MOD_GlcNHglycan	313	316	PF01048	0.546
MOD_GlcNHglycan	346	349	PF01048	0.661
MOD_GlcNHglycan	364	367	PF01048	0.555
MOD_GlcNHglycan	389	392	PF01048	0.564
MOD_GlcNHglycan	400	403	PF01048	0.499
MOD_GlcNHglycan	79	82	PF01048	0.584
MOD_GlcNHglycan	99	102	PF01048	0.581
MOD_GSK3_1	104	111	PF00069	0.591
MOD_GSK3_1	17	24	PF00069	0.571
MOD_GSK3_1	225	232	PF00069	0.646
MOD_GSK3_1	257	264	PF00069	0.668
MOD_GSK3_1	291	298	PF00069	0.698
MOD_GSK3_1	333	340	PF00069	0.565
MOD_GSK3_1	387	394	PF00069	0.577
MOD_GSK3_1	40	47	PF00069	0.636
MOD_GSK3_1	77	84	PF00069	0.669
MOD_GSK3_1	95	102	PF00069	0.621
MOD_N-GLC_1	261	266	PF02516	0.473
MOD_N-GLC_1	4	9	PF02516	0.575
MOD_N-GLC_2	142	144	PF02516	0.614
MOD_NEK2_1	171	176	PF00069	0.549
MOD_NEK2_1	180	185	PF00069	0.536
MOD_NEK2_1	28	33	PF00069	0.554
MOD_NEK2_1	327	332	PF00069	0.521
MOD_NEK2_1	386	391	PF00069	0.641
MOD_NEK2_1	396	401	PF00069	0.497
MOD_NEK2_1	89	94	PF00069	0.584
MOD_NEK2_2	14	19	PF00069	0.478
MOD_PKA_2	225	231	PF00069	0.535
MOD_PKA_2	387	393	PF00069	0.571
MOD_PKB_1	372	380	PF00069	0.558
MOD_Plk_1	171	177	PF00069	0.532
MOD_Plk_1	391	397	PF00069	0.595
MOD_Plk_1	81	87	PF00069	0.565
MOD_Plk_4	14	20	PF00069	0.476
MOD_Plk_4	291	297	PF00069	0.597
MOD_Plk_4	374	380	PF00069	0.539
MOD_Plk_4	391	397	PF00069	0.538
MOD_Plk_4	89	95	PF00069	0.495
MOD_ProDKin_1	262	268	PF00069	0.675
TRG_DiLeu_BaLyEn_6	219	224	PF01217	0.495
TRG_ENDOCYTIC_2	278	281	PF00928	0.507
TRG_ENDOCYTIC_2	356	359	PF00928	0.657
TRG_ENDOCYTIC_2	409	412	PF00928	0.571
TRG_ENDOCYTIC_2	417	420	PF00928	0.468
TRG_ER_diArg_1	187	190	PF00400	0.643
TRG_Pf-PMV_PEXEL_1	50	54	PF00026	0.520

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2P5	Leptomonas seymouri	36%	90%
A0A3S7X9Q8	Leishmania donovani	89%	100%
A4HN22	Leishmania braziliensis	73%	100%
A4IBP6	Leishmania infantum	89%	100%
E9AFH7	Leishmania major	90%	100%