Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B6M1_LEIMU

TriTrypDb:

LmxM.34.3420

Length:

189

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6M1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6M1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	124	126	PF00675	0.644
CLV_PCSK_KEX2_1	124	126	PF00082	0.637
CLV_PCSK_PC7_1	120	126	PF00082	0.546
CLV_PCSK_SKI1_1	115	119	PF00082	0.421
CLV_PCSK_SKI1_1	91	95	PF00082	0.590
DEG_Nend_UBRbox_1	1	4	PF02207	0.627
DEG_SPOP_SBC_1	54	58	PF00917	0.623
DOC_PP4_FxxP_1	10	13	PF00568	0.643
DOC_PP4_FxxP_1	186	189	PF00568	0.483
DOC_PP4_FxxP_1	75	78	PF00568	0.754
DOC_USP7_MATH_1	43	47	PF00917	0.634
DOC_USP7_MATH_1	54	58	PF00917	0.683
DOC_USP7_MATH_1	6	10	PF00917	0.666
DOC_USP7_MATH_1	69	73	PF00917	0.551
DOC_USP7_MATH_1	97	101	PF00917	0.683
LIG_14-3-3_CanoR_1	165	174	PF00244	0.495
LIG_14-3-3_CanoR_1	2	10	PF00244	0.619
LIG_14-3-3_CanoR_1	91	97	PF00244	0.704
LIG_BRCT_BRCA1_1	71	75	PF00533	0.681
LIG_Clathr_ClatBox_1	178	182	PF01394	0.532
LIG_FHA_1	129	135	PF00498	0.421
LIG_FHA_1	93	99	PF00498	0.720
LIG_LIR_Apic_2	183	189	PF02991	0.474
LIG_LIR_Apic_2	72	78	PF02991	0.757
LIG_LIR_Apic_2	9	13	PF02991	0.642
LIG_LIR_Gen_1	140	151	PF02991	0.504
LIG_LIR_Nem_3	140	146	PF02991	0.498
LIG_Pex14_2	10	14	PF04695	0.643
LIG_SH2_STAP1	39	43	PF00017	0.467
LIG_SH3_3	59	65	PF00018	0.614
LIG_SH3_3	68	74	PF00018	0.555
LIG_TRAF2_1	180	183	PF00917	0.600
MOD_CK1_1	100	106	PF00069	0.640
MOD_CK2_1	177	183	PF00069	0.599
MOD_GSK3_1	128	135	PF00069	0.483
MOD_GSK3_1	173	180	PF00069	0.701
MOD_GSK3_1	69	76	PF00069	0.673
MOD_N-GLC_1	54	59	PF02516	0.618
MOD_NEK2_1	1	6	PF00069	0.630
MOD_NEK2_1	128	133	PF00069	0.475
MOD_NEK2_1	14	19	PF00069	0.659
MOD_NEK2_1	33	38	PF00069	0.639
MOD_NEK2_2	6	11	PF00069	0.654
MOD_PIKK_1	128	134	PF00454	0.461
MOD_PIKK_1	144	150	PF00454	0.503
MOD_PIKK_1	33	39	PF00454	0.639
MOD_PIKK_1	69	75	PF00454	0.509
MOD_PKA_1	79	85	PF00069	0.523
MOD_PKA_2	1	7	PF00069	0.630
MOD_Plk_4	132	138	PF00069	0.486
MOD_Plk_4	173	179	PF00069	0.590
TRG_Pf-PMV_PEXEL_1	115	119	PF00026	0.617
TRG_Pf-PMV_PEXEL_1	165	169	PF00026	0.424

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IIJ1	Leishmania donovani	82%	100%
A4HN09	Leishmania braziliensis	68%	100%
A4IBN2	Leishmania infantum	82%	100%
E9AFG6	Leishmania major	86%	100%