Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B6L8_LEIMU

TriTrypDb:

LmxM.34.3390

Length:

262

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6L8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6L8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	205	209	PF00656	0.547
CLV_NRD_NRD_1	228	230	PF00675	0.583
CLV_PCSK_KEX2_1	228	230	PF00082	0.583
CLV_PCSK_SKI1_1	183	187	PF00082	0.596
CLV_PCSK_SKI1_1	28	32	PF00082	0.634
CLV_Separin_Metazoa	15	19	PF03568	0.653
DEG_SCF_FBW7_1	172	179	PF00400	0.734
DEG_SPOP_SBC_1	176	180	PF00917	0.682
DEG_SPOP_SBC_1	255	259	PF00917	0.487
DOC_CKS1_1	173	178	PF01111	0.746
DOC_PP4_FxxP_1	93	96	PF00568	0.777
DOC_PP4_MxPP_1	235	238	PF00568	0.530
DOC_USP7_MATH_1	160	164	PF00917	0.707
DOC_USP7_MATH_1	176	180	PF00917	0.682
DOC_WW_Pin1_4	127	132	PF00397	0.478
DOC_WW_Pin1_4	146	151	PF00397	0.634
DOC_WW_Pin1_4	172	177	PF00397	0.755
DOC_WW_Pin1_4	7	12	PF00397	0.392
DOC_WW_Pin1_4	83	88	PF00397	0.730
DOC_WW_Pin1_4	91	96	PF00397	0.649
LIG_14-3-3_CanoR_1	189	193	PF00244	0.501
LIG_BIR_II_1	1	5	PF00653	0.660
LIG_FHA_1	58	64	PF00498	0.291
LIG_FHA_2	10	16	PF00498	0.657
LIG_FHA_2	189	195	PF00498	0.297
LIG_FHA_2	51	57	PF00498	0.590
LIG_LIR_Apic_2	90	96	PF02991	0.775
LIG_LIR_Gen_1	42	48	PF02991	0.573
LIG_LIR_LC3C_4	218	221	PF02991	0.436
LIG_LIR_LC3C_4	240	244	PF02991	0.292
LIG_LIR_Nem_3	10	16	PF02991	0.615
LIG_LIR_Nem_3	42	47	PF02991	0.515
LIG_SH2_PTP2	123	126	PF00017	0.476
LIG_SH2_STAT5	123	126	PF00017	0.482
LIG_SH2_STAT5	127	130	PF00017	0.519
LIG_SH2_STAT5	184	187	PF00017	0.460
LIG_SH3_3	141	147	PF00018	0.531
LIG_SH3_3	170	176	PF00018	0.695
LIG_SH3_3	227	233	PF00018	0.514
LIG_SH3_3	79	85	PF00018	0.686
LIG_SH3_3	8	14	PF00018	0.676
LIG_SH3_3	89	95	PF00018	0.622
LIG_SUMO_SIM_par_1	59	64	PF11976	0.290
MOD_CK2_1	105	111	PF00069	0.658
MOD_CK2_1	255	261	PF00069	0.521
MOD_CK2_1	50	56	PF00069	0.605
MOD_CK2_1	75	81	PF00069	0.500
MOD_CK2_1	9	15	PF00069	0.595
MOD_Cter_Amidation	226	229	PF01082	0.570
MOD_GSK3_1	101	108	PF00069	0.393
MOD_GSK3_1	127	134	PF00069	0.443
MOD_GSK3_1	172	179	PF00069	0.679
MOD_GSK3_1	50	57	PF00069	0.478
MOD_GSK3_1	83	90	PF00069	0.660
MOD_NEK2_1	126	131	PF00069	0.465
MOD_NEK2_1	254	259	PF00069	0.390
MOD_OFUCOSY	128	135	PF10250	0.513
MOD_PKA_2	188	194	PF00069	0.503
MOD_PKA_2	231	237	PF00069	0.550
MOD_PKB_1	52	60	PF00069	0.525
MOD_Plk_2-3	9	15	PF00069	0.613
MOD_Plk_4	231	237	PF00069	0.548
MOD_Plk_4	39	45	PF00069	0.627
MOD_Plk_4	57	63	PF00069	0.349
MOD_ProDKin_1	127	133	PF00069	0.469
MOD_ProDKin_1	146	152	PF00069	0.643
MOD_ProDKin_1	172	178	PF00069	0.742
MOD_ProDKin_1	7	13	PF00069	0.391
MOD_ProDKin_1	83	89	PF00069	0.733
MOD_ProDKin_1	91	97	PF00069	0.649
MOD_SUMO_rev_2	208	216	PF00179	0.516
TRG_DiLeu_BaEn_4	111	117	PF01217	0.462
TRG_ENDOCYTIC_2	123	126	PF00928	0.525
TRG_ER_diArg_1	228	230	PF00400	0.583
TRG_NES_CRM1_1	66	81	PF08389	0.593

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1X1	Leptomonas seymouri	41%	97%
A0A3Q8II73	Leishmania donovani	87%	100%
A4HN06	Leishmania braziliensis	76%	100%
A4IBM9	Leishmania infantum	87%	100%
E9AFG3	Leishmania major	87%	100%
V5BYA4	Trypanosoma cruzi	24%	100%