Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

class I transcription factor A, subunit 2, putative

Species:

Leishmania mexicana

UniProt:

E9B6J4_LEIMU

TriTrypDb:

LmxM.34.3150

Length:

515

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6J4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6J4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	175	179	PF00656	0.675
CLV_C14_Caspase3-7	343	347	PF00656	0.627
CLV_NRD_NRD_1	226	228	PF00675	0.552
CLV_NRD_NRD_1	249	251	PF00675	0.542
CLV_NRD_NRD_1	295	297	PF00675	0.760
CLV_NRD_NRD_1	316	318	PF00675	0.628
CLV_NRD_NRD_1	376	378	PF00675	0.749
CLV_NRD_NRD_1	434	436	PF00675	0.766
CLV_NRD_NRD_1	484	486	PF00675	0.609
CLV_NRD_NRD_1	494	496	PF00675	0.602
CLV_NRD_NRD_1	91	93	PF00675	0.725
CLV_PCSK_KEX2_1	226	228	PF00082	0.474
CLV_PCSK_KEX2_1	249	251	PF00082	0.518
CLV_PCSK_KEX2_1	316	318	PF00082	0.628
CLV_PCSK_KEX2_1	34	36	PF00082	0.652
CLV_PCSK_KEX2_1	362	364	PF00082	0.817
CLV_PCSK_KEX2_1	376	378	PF00082	0.591
CLV_PCSK_KEX2_1	434	436	PF00082	0.766
CLV_PCSK_KEX2_1	483	485	PF00082	0.613
CLV_PCSK_KEX2_1	494	496	PF00082	0.579
CLV_PCSK_KEX2_1	91	93	PF00082	0.711
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.652
CLV_PCSK_PC1ET2_1	362	364	PF00082	0.817
CLV_PCSK_PC7_1	358	364	PF00082	0.823
CLV_PCSK_PC7_1	490	496	PF00082	0.627
CLV_PCSK_SKI1_1	115	119	PF00082	0.569
CLV_PCSK_SKI1_1	181	185	PF00082	0.481
CLV_PCSK_SKI1_1	316	320	PF00082	0.755
CLV_PCSK_SKI1_1	494	498	PF00082	0.614
CLV_PCSK_SKI1_1	86	90	PF00082	0.746
DEG_APCC_DBOX_1	229	237	PF00400	0.598
DEG_APCC_DBOX_1	484	492	PF00400	0.458
DEG_SPOP_SBC_1	183	187	PF00917	0.474
DEG_SPOP_SBC_1	421	425	PF00917	0.753
DOC_CKS1_1	13	18	PF01111	0.543
DOC_CYCLIN_RxL_1	218	229	PF00134	0.585
DOC_MAPK_gen_1	316	324	PF00069	0.626
DOC_MAPK_gen_1	376	386	PF00069	0.748
DOC_MAPK_MEF2A_6	466	475	PF00069	0.713
DOC_PP1_RVXF_1	219	226	PF00149	0.510
DOC_PP1_RVXF_1	84	91	PF00149	0.689
DOC_PP2B_LxvP_1	473	476	PF13499	0.768
DOC_USP7_MATH_1	166	170	PF00917	0.724
DOC_USP7_MATH_1	183	187	PF00917	0.691
DOC_USP7_MATH_1	367	371	PF00917	0.761
DOC_USP7_MATH_1	422	426	PF00917	0.784
DOC_USP7_MATH_1	498	502	PF00917	0.626
DOC_USP7_MATH_1	62	66	PF00917	0.567
DOC_WW_Pin1_4	12	17	PF00397	0.548
DOC_WW_Pin1_4	285	290	PF00397	0.667
DOC_WW_Pin1_4	415	420	PF00397	0.803
DOC_WW_Pin1_4	97	102	PF00397	0.497
LIG_14-3-3_CanoR_1	115	125	PF00244	0.558
LIG_14-3-3_CanoR_1	128	132	PF00244	0.390
LIG_14-3-3_CanoR_1	181	191	PF00244	0.707
LIG_14-3-3_CanoR_1	237	247	PF00244	0.700
LIG_14-3-3_CanoR_1	316	324	PF00244	0.750
LIG_14-3-3_CanoR_1	365	375	PF00244	0.740
LIG_14-3-3_CanoR_1	435	441	PF00244	0.465
LIG_14-3-3_CanoR_1	507	512	PF00244	0.752
LIG_BRCT_BRCA1_1	500	504	PF00533	0.586
LIG_deltaCOP1_diTrp_1	433	443	PF00928	0.684
LIG_FHA_1	124	130	PF00498	0.321
LIG_FHA_1	165	171	PF00498	0.673
LIG_FHA_1	317	323	PF00498	0.756
LIG_FHA_1	416	422	PF00498	0.688
LIG_FHA_1	425	431	PF00498	0.748
LIG_FHA_1	79	85	PF00498	0.667
LIG_FHA_2	173	179	PF00498	0.739
LIG_FHA_2	211	217	PF00498	0.550
LIG_FHA_2	324	330	PF00498	0.683
LIG_GBD_Chelix_1	104	112	PF00786	0.530
LIG_LIR_Gen_1	216	225	PF02991	0.276
LIG_LIR_Gen_1	259	268	PF02991	0.537
LIG_LIR_Nem_3	130	136	PF02991	0.588
LIG_LIR_Nem_3	216	220	PF02991	0.404
LIG_LIR_Nem_3	259	265	PF02991	0.530
LIG_Pex14_2	262	266	PF04695	0.529
LIG_SH2_CRK	11	15	PF00017	0.434
LIG_SH2_CRK	469	473	PF00017	0.771
LIG_SH2_CRK	493	497	PF00017	0.681
LIG_SH2_NCK_1	11	15	PF00017	0.434
LIG_SH2_STAT5	277	280	PF00017	0.495
LIG_SH3_2	16	21	PF14604	0.664
LIG_SH3_3	13	19	PF00018	0.668
LIG_SH3_3	416	422	PF00018	0.691
LIG_SH3_3	50	56	PF00018	0.442
LIG_SH3_3	91	97	PF00018	0.611
LIG_SUMO_SIM_par_1	250	256	PF11976	0.530
LIG_SUMO_SIM_par_1	329	337	PF11976	0.542
LIG_SxIP_EBH_1	52	66	PF03271	0.667
LIG_TYR_ITIM	491	496	PF00017	0.594
MOD_CDK_SPK_2	12	17	PF00069	0.548
MOD_CK1_1	134	140	PF00069	0.395
MOD_CK1_1	169	175	PF00069	0.717
MOD_CK1_1	187	193	PF00069	0.692
MOD_CK1_1	194	200	PF00069	0.660
MOD_CK1_1	323	329	PF00069	0.717
MOD_CK1_1	424	430	PF00069	0.697
MOD_CK1_1	444	450	PF00069	0.722
MOD_CK2_1	210	216	PF00069	0.555
MOD_CK2_1	238	244	PF00069	0.625
MOD_CK2_1	422	428	PF00069	0.737
MOD_CK2_1	62	68	PF00069	0.698
MOD_GlcNHglycan	193	196	PF01048	0.686
MOD_GlcNHglycan	279	282	PF01048	0.642
MOD_GlcNHglycan	358	361	PF01048	0.724
MOD_GlcNHglycan	424	427	PF01048	0.752
MOD_GlcNHglycan	438	441	PF01048	0.636
MOD_GlcNHglycan	443	446	PF01048	0.629
MOD_GlcNHglycan	500	503	PF01048	0.419
MOD_GSK3_1	123	130	PF00069	0.436
MOD_GSK3_1	183	190	PF00069	0.734
MOD_GSK3_1	316	323	PF00069	0.756
MOD_GSK3_1	352	359	PF00069	0.748
MOD_GSK3_1	363	370	PF00069	0.747
MOD_GSK3_1	417	424	PF00069	0.654
MOD_N-GLC_1	320	325	PF02516	0.668
MOD_NEK2_1	131	136	PF00069	0.585
MOD_NEK2_1	182	187	PF00069	0.731
MOD_NEK2_1	205	210	PF00069	0.525
MOD_NEK2_1	266	271	PF00069	0.558
MOD_NEK2_1	449	454	PF00069	0.688
MOD_PIKK_1	134	140	PF00454	0.556
MOD_PIKK_1	169	175	PF00454	0.665
MOD_PIKK_1	184	190	PF00454	0.643
MOD_PIKK_1	3	9	PF00454	0.613
MOD_PIKK_1	300	306	PF00454	0.559
MOD_PIKK_1	444	450	PF00454	0.722
MOD_PK_1	239	245	PF00069	0.705
MOD_PKA_1	226	232	PF00069	0.536
MOD_PKA_1	316	322	PF00069	0.756
MOD_PKA_1	484	490	PF00069	0.687
MOD_PKA_2	127	133	PF00069	0.616
MOD_PKA_2	226	232	PF00069	0.536
MOD_PKA_2	238	244	PF00069	0.548
MOD_PKA_2	316	322	PF00069	0.756
MOD_PKA_2	484	490	PF00069	0.626
MOD_PKA_2	78	84	PF00069	0.658
MOD_PKB_1	237	245	PF00069	0.714
MOD_Plk_1	177	183	PF00069	0.610
MOD_Plk_1	320	326	PF00069	0.635
MOD_Plk_4	166	172	PF00069	0.722
MOD_Plk_4	205	211	PF00069	0.540
MOD_ProDKin_1	12	18	PF00069	0.545
MOD_ProDKin_1	285	291	PF00069	0.670
MOD_ProDKin_1	415	421	PF00069	0.802
MOD_ProDKin_1	97	103	PF00069	0.501
MOD_SUMO_rev_2	280	289	PF00179	0.716
TRG_DiLeu_BaLyEn_6	468	473	PF01217	0.775
TRG_DiLeu_BaLyEn_6	492	497	PF01217	0.682
TRG_ENDOCYTIC_2	469	472	PF00928	0.770
TRG_ENDOCYTIC_2	493	496	PF00928	0.691
TRG_ER_diArg_1	112	115	PF00400	0.567
TRG_ER_diArg_1	225	227	PF00400	0.538
TRG_ER_diArg_1	236	239	PF00400	0.627
TRG_ER_diArg_1	249	251	PF00400	0.457
TRG_ER_diArg_1	315	317	PF00400	0.629
TRG_ER_diArg_1	375	377	PF00400	0.650
TRG_ER_diArg_1	380	383	PF00400	0.663
TRG_ER_diArg_1	434	436	PF00400	0.682
TRG_ER_diArg_1	483	485	PF00400	0.649
TRG_ER_diArg_1	493	495	PF00400	0.584
TRG_ER_diArg_1	76	79	PF00400	0.561
TRG_ER_diArg_1	90	92	PF00400	0.751

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5S0	Leptomonas seymouri	41%	98%
A0A3R7MGU2	Trypanosoma rangeli	26%	100%
A0A3S7X9K7	Leishmania donovani	88%	100%
A4HMY2	Leishmania braziliensis	71%	99%
A4IBK6	Leishmania infantum	88%	100%
E9AFD9	Leishmania major	89%	100%