LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

VASt domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
VASt domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B6I6_LEIMU
TriTrypDb:
LmxM.34.3070
Length:
822

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6I6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6I6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 636 640 PF00656 0.547
CLV_MEL_PAP_1 78 84 PF00089 0.387
CLV_NRD_NRD_1 333 335 PF00675 0.478
CLV_NRD_NRD_1 726 728 PF00675 0.459
CLV_PCSK_FUR_1 331 335 PF00082 0.420
CLV_PCSK_KEX2_1 331 333 PF00082 0.534
CLV_PCSK_KEX2_1 505 507 PF00082 0.466
CLV_PCSK_KEX2_1 618 620 PF00082 0.507
CLV_PCSK_KEX2_1 726 728 PF00082 0.461
CLV_PCSK_KEX2_1 805 807 PF00082 0.426
CLV_PCSK_PC1ET2_1 505 507 PF00082 0.466
CLV_PCSK_PC1ET2_1 618 620 PF00082 0.394
CLV_PCSK_PC1ET2_1 805 807 PF00082 0.426
CLV_PCSK_PC7_1 328 334 PF00082 0.348
CLV_PCSK_SKI1_1 171 175 PF00082 0.354
CLV_PCSK_SKI1_1 27 31 PF00082 0.594
CLV_PCSK_SKI1_1 385 389 PF00082 0.467
CLV_PCSK_SKI1_1 490 494 PF00082 0.550
CLV_PCSK_SKI1_1 531 535 PF00082 0.555
CLV_PCSK_SKI1_1 570 574 PF00082 0.398
CLV_PCSK_SKI1_1 579 583 PF00082 0.373
CLV_PCSK_SKI1_1 592 596 PF00082 0.256
CLV_PCSK_SKI1_1 611 615 PF00082 0.335
CLV_PCSK_SKI1_1 648 652 PF00082 0.491
CLV_PCSK_SKI1_1 806 810 PF00082 0.423
CLV_PCSK_SKI1_1 87 91 PF00082 0.383
DOC_MAPK_gen_1 235 245 PF00069 0.463
DOC_MAPK_gen_1 286 296 PF00069 0.432
DOC_MAPK_gen_1 618 625 PF00069 0.359
DOC_MAPK_gen_1 726 733 PF00069 0.419
DOC_MAPK_gen_1 805 812 PF00069 0.445
DOC_MAPK_MEF2A_6 186 194 PF00069 0.462
DOC_MAPK_MEF2A_6 238 245 PF00069 0.371
DOC_MAPK_MEF2A_6 618 627 PF00069 0.399
DOC_PP1_RVXF_1 569 576 PF00149 0.472
DOC_PP2B_LxvP_1 172 175 PF13499 0.355
DOC_PP2B_LxvP_1 652 655 PF13499 0.530
DOC_PP4_FxxP_1 560 563 PF00568 0.349
DOC_PP4_FxxP_1 643 646 PF00568 0.439
DOC_PP4_FxxP_1 792 795 PF00568 0.498
DOC_USP7_MATH_1 447 451 PF00917 0.340
DOC_USP7_MATH_1 50 54 PF00917 0.443
DOC_USP7_MATH_1 511 515 PF00917 0.540
DOC_USP7_MATH_1 646 650 PF00917 0.499
DOC_USP7_MATH_1 739 743 PF00917 0.307
DOC_USP7_MATH_1 795 799 PF00917 0.600
DOC_USP7_MATH_1 800 804 PF00917 0.418
DOC_USP7_MATH_1 98 102 PF00917 0.480
DOC_USP7_UBL2_3 196 200 PF12436 0.455
DOC_USP7_UBL2_3 531 535 PF12436 0.412
DOC_USP7_UBL2_3 805 809 PF12436 0.427
DOC_WW_Pin1_4 539 544 PF00397 0.358
DOC_WW_Pin1_4 813 818 PF00397 0.644
LIG_14-3-3_CanoR_1 186 194 PF00244 0.423
LIG_14-3-3_CanoR_1 258 266 PF00244 0.423
LIG_14-3-3_CanoR_1 289 296 PF00244 0.406
LIG_14-3-3_CanoR_1 32 38 PF00244 0.417
LIG_14-3-3_CanoR_1 363 372 PF00244 0.341
LIG_14-3-3_CanoR_1 432 438 PF00244 0.297
LIG_14-3-3_CanoR_1 579 584 PF00244 0.509
LIG_14-3-3_CanoR_1 592 597 PF00244 0.316
LIG_14-3-3_CanoR_1 75 79 PF00244 0.552
LIG_APCC_ABBAyCdc20_2 483 489 PF00400 0.350
LIG_BRCT_BRCA1_1 58 62 PF00533 0.449
LIG_BRCT_BRCA1_1 629 633 PF00533 0.444
LIG_BRCT_BRCA1_1 639 643 PF00533 0.548
LIG_deltaCOP1_diTrp_1 737 747 PF00928 0.479
LIG_deltaCOP1_diTrp_1 74 82 PF00928 0.390
LIG_deltaCOP1_diTrp_1 772 778 PF00928 0.392
LIG_FHA_1 214 220 PF00498 0.391
LIG_FHA_1 255 261 PF00498 0.415
LIG_FHA_1 276 282 PF00498 0.412
LIG_FHA_1 289 295 PF00498 0.326
LIG_FHA_1 3 9 PF00498 0.441
LIG_FHA_1 367 373 PF00498 0.385
LIG_FHA_1 407 413 PF00498 0.291
LIG_FHA_1 453 459 PF00498 0.338
LIG_FHA_1 591 597 PF00498 0.301
LIG_FHA_1 703 709 PF00498 0.448
LIG_FHA_2 121 127 PF00498 0.438
LIG_FHA_2 186 192 PF00498 0.482
LIG_FHA_2 720 726 PF00498 0.508
LIG_Integrin_RGD_1 473 475 PF01839 0.389
LIG_KLC1_Yacidic_2 760 764 PF13176 0.449
LIG_LIR_Apic_2 640 646 PF02991 0.487
LIG_LIR_Gen_1 514 522 PF02991 0.403
LIG_LIR_Gen_1 737 748 PF02991 0.418
LIG_LIR_Gen_1 93 100 PF02991 0.394
LIG_LIR_Nem_3 310 316 PF02991 0.444
LIG_LIR_Nem_3 36 40 PF02991 0.471
LIG_LIR_Nem_3 491 496 PF02991 0.563
LIG_LIR_Nem_3 514 518 PF02991 0.400
LIG_LIR_Nem_3 555 559 PF02991 0.338
LIG_LIR_Nem_3 737 743 PF02991 0.383
LIG_LIR_Nem_3 772 778 PF02991 0.333
LIG_LIR_Nem_3 93 97 PF02991 0.319
LIG_NRBOX 548 554 PF00104 0.385
LIG_Pex14_1 58 62 PF04695 0.370
LIG_Pex14_1 580 584 PF04695 0.434
LIG_PTB_Apo_2 785 792 PF02174 0.394
LIG_PTB_Phospho_1 785 791 PF10480 0.393
LIG_SH2_CRK 376 380 PF00017 0.221
LIG_SH2_CRK 556 560 PF00017 0.318
LIG_SH2_CRK 591 595 PF00017 0.420
LIG_SH2_STAP1 217 221 PF00017 0.411
LIG_SH2_STAT3 776 779 PF00017 0.468
LIG_SH2_STAT5 217 220 PF00017 0.452
LIG_SH2_STAT5 558 561 PF00017 0.286
LIG_SH2_STAT5 631 634 PF00017 0.539
LIG_SH2_STAT5 762 765 PF00017 0.444
LIG_SH2_STAT5 791 794 PF00017 0.437
LIG_SH3_3 100 106 PF00018 0.515
LIG_SH3_3 206 212 PF00018 0.407
LIG_SH3_3 408 414 PF00018 0.327
LIG_SH3_3 416 422 PF00018 0.270
LIG_SH3_3 7 13 PF00018 0.622
LIG_SH3_3 811 817 PF00018 0.590
LIG_SUMO_SIM_anti_2 455 460 PF11976 0.177
LIG_SUMO_SIM_anti_2 96 102 PF11976 0.371
LIG_SUMO_SIM_par_1 239 244 PF11976 0.364
LIG_SUMO_SIM_par_1 729 734 PF11976 0.408
LIG_TRAF2_1 23 26 PF00917 0.479
LIG_TRAF2_1 320 323 PF00917 0.489
LIG_TRAF2_1 438 441 PF00917 0.335
LIG_TRAF2_2 175 180 PF00917 0.429
LIG_TRFH_1 539 543 PF08558 0.361
LIG_TYR_ITIM 589 594 PF00017 0.417
LIG_UBA3_1 143 151 PF00899 0.468
LIG_UBA3_1 348 354 PF00899 0.297
MOD_CK1_1 110 116 PF00069 0.565
MOD_CK1_1 366 372 PF00069 0.485
MOD_CK1_1 381 387 PF00069 0.265
MOD_CK1_1 403 409 PF00069 0.280
MOD_CK1_1 697 703 PF00069 0.380
MOD_CK1_1 816 822 PF00069 0.622
MOD_CK2_1 120 126 PF00069 0.429
MOD_CK2_1 20 26 PF00069 0.492
MOD_CK2_1 317 323 PF00069 0.416
MOD_CK2_1 447 453 PF00069 0.364
MOD_CK2_1 653 659 PF00069 0.445
MOD_CK2_1 719 725 PF00069 0.492
MOD_GlcNHglycan 20 25 PF01048 0.448
MOD_GlcNHglycan 365 368 PF01048 0.297
MOD_GlcNHglycan 380 383 PF01048 0.382
MOD_GlcNHglycan 391 394 PF01048 0.281
MOD_GlcNHglycan 500 503 PF01048 0.352
MOD_GlcNHglycan 52 55 PF01048 0.494
MOD_GlcNHglycan 586 589 PF01048 0.473
MOD_GlcNHglycan 755 758 PF01048 0.483
MOD_GlcNHglycan 818 821 PF01048 0.634
MOD_GSK3_1 181 188 PF00069 0.461
MOD_GSK3_1 271 278 PF00069 0.427
MOD_GSK3_1 281 288 PF00069 0.463
MOD_GSK3_1 353 360 PF00069 0.345
MOD_GSK3_1 400 407 PF00069 0.290
MOD_GSK3_1 637 644 PF00069 0.499
MOD_GSK3_1 70 77 PF00069 0.518
MOD_GSK3_1 749 756 PF00069 0.442
MOD_GSK3_1 790 797 PF00069 0.451
MOD_LATS_1 609 615 PF00433 0.301
MOD_N-GLC_1 118 123 PF02516 0.497
MOD_N-GLC_1 467 472 PF02516 0.478
MOD_NEK2_1 254 259 PF00069 0.567
MOD_NEK2_1 271 276 PF00069 0.446
MOD_NEK2_1 281 286 PF00069 0.394
MOD_NEK2_1 33 38 PF00069 0.434
MOD_NEK2_1 359 364 PF00069 0.372
MOD_NEK2_1 433 438 PF00069 0.303
MOD_NEK2_1 477 482 PF00069 0.470
MOD_NEK2_1 552 557 PF00069 0.320
MOD_NEK2_1 667 672 PF00069 0.372
MOD_NEK2_1 694 699 PF00069 0.359
MOD_NEK2_1 790 795 PF00069 0.516
MOD_NEK2_1 90 95 PF00069 0.364
MOD_NEK2_2 195 200 PF00069 0.477
MOD_NEK2_2 215 220 PF00069 0.236
MOD_NEK2_2 375 380 PF00069 0.341
MOD_NEK2_2 800 805 PF00069 0.425
MOD_PIKK_1 353 359 PF00454 0.177
MOD_PIKK_1 541 547 PF00454 0.469
MOD_PK_1 48 54 PF00069 0.467
MOD_PKA_2 185 191 PF00069 0.476
MOD_PKA_2 285 291 PF00069 0.385
MOD_PKA_2 303 309 PF00069 0.326
MOD_PKA_2 74 80 PF00069 0.553
MOD_Plk_1 107 113 PF00069 0.598
MOD_Plk_1 118 124 PF00069 0.414
MOD_Plk_1 241 247 PF00069 0.363
MOD_Plk_1 25 31 PF00069 0.421
MOD_Plk_1 269 275 PF00069 0.397
MOD_Plk_1 309 315 PF00069 0.417
MOD_Plk_1 400 406 PF00069 0.372
MOD_Plk_1 719 725 PF00069 0.490
MOD_Plk_1 781 787 PF00069 0.526
MOD_Plk_2-3 25 31 PF00069 0.563
MOD_Plk_2-3 719 725 PF00069 0.481
MOD_Plk_4 107 113 PF00069 0.557
MOD_Plk_4 241 247 PF00069 0.456
MOD_Plk_4 303 309 PF00069 0.465
MOD_Plk_4 400 406 PF00069 0.422
MOD_Plk_4 454 460 PF00069 0.225
MOD_Plk_4 579 585 PF00069 0.417
MOD_Plk_4 611 617 PF00069 0.327
MOD_Plk_4 627 633 PF00069 0.498
MOD_Plk_4 653 659 PF00069 0.551
MOD_Plk_4 667 673 PF00069 0.320
MOD_Plk_4 702 708 PF00069 0.502
MOD_Plk_4 719 725 PF00069 0.439
MOD_Plk_4 781 787 PF00069 0.460
MOD_ProDKin_1 539 545 PF00069 0.351
MOD_ProDKin_1 813 819 PF00069 0.648
MOD_SUMO_rev_2 20 29 PF00179 0.503
MOD_SUMO_rev_2 565 572 PF00179 0.360
TRG_DiLeu_BaEn_1 520 525 PF01217 0.370
TRG_DiLeu_BaEn_2 321 327 PF01217 0.459
TRG_DiLeu_BaEn_2 724 730 PF01217 0.488
TRG_DiLeu_BaEn_3 337 343 PF01217 0.434
TRG_DiLeu_BaLyEn_6 276 281 PF01217 0.410
TRG_ENDOCYTIC_2 130 133 PF00928 0.384
TRG_ENDOCYTIC_2 376 379 PF00928 0.305
TRG_ENDOCYTIC_2 556 559 PF00928 0.362
TRG_ENDOCYTIC_2 591 594 PF00928 0.366
TRG_ER_diArg_1 16 19 PF00400 0.681
TRG_ER_diArg_1 330 333 PF00400 0.530
TRG_ER_diArg_1 78 81 PF00400 0.438
TRG_Pf-PMV_PEXEL_1 27 31 PF00026 0.571
TRG_Pf-PMV_PEXEL_1 759 764 PF00026 0.458

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HV37 Leptomonas seymouri 62% 100%
A0A0S4JPI8 Bodo saltans 26% 100%
A0A1X0P5E4 Trypanosomatidae 32% 100%
A0A3Q8IVD1 Leishmania donovani 93% 100%
A4HMX4 Leishmania braziliensis 82% 100%
A4IBJ5 Leishmania infantum 93% 100%
E9AFD1 Leishmania major 92% 100%
V5C2X4 Trypanosoma cruzi 32% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS