LeishMANIAdb
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Transporter-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Transporter-like protein
Gene product:
transporter-like protein
Species:
Leishmania mexicana
UniProt:
E9B6F7_LEIMU
TriTrypDb:
LmxM.34.2780
Length:
697

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 12
NetGPI no yes: 0, no: 12
Cellular components
Term Name Level Count
GO:0016020 membrane 2 13
GO:0110165 cellular anatomical entity 1 13

Expansion

Sequence features

E9B6F7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6F7

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0005215 transporter activity 1 13
GO:0022857 transmembrane transporter activity 2 13

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 542 546 PF00656 0.768
CLV_C14_Caspase3-7 550 554 PF00656 0.625
CLV_NRD_NRD_1 105 107 PF00675 0.218
CLV_NRD_NRD_1 25 27 PF00675 0.351
CLV_NRD_NRD_1 326 328 PF00675 0.332
CLV_NRD_NRD_1 432 434 PF00675 0.546
CLV_NRD_NRD_1 5 7 PF00675 0.324
CLV_NRD_NRD_1 548 550 PF00675 0.527
CLV_NRD_NRD_1 625 627 PF00675 0.409
CLV_PCSK_KEX2_1 25 27 PF00082 0.368
CLV_PCSK_KEX2_1 326 328 PF00082 0.331
CLV_PCSK_KEX2_1 5 7 PF00082 0.324
CLV_PCSK_KEX2_1 548 550 PF00082 0.527
CLV_PCSK_KEX2_1 625 627 PF00082 0.409
CLV_PCSK_SKI1_1 246 250 PF00082 0.370
CLV_PCSK_SKI1_1 317 321 PF00082 0.279
DEG_APCC_DBOX_1 326 334 PF00400 0.543
DEG_APCC_DBOX_1 624 632 PF00400 0.727
DEG_Nend_Nbox_1 1 3 PF02207 0.521
DOC_CKS1_1 487 492 PF01111 0.235
DOC_CYCLIN_RxL_1 162 173 PF00134 0.502
DOC_CYCLIN_yClb5_NLxxxL_5 220 229 PF00134 0.140
DOC_MAPK_FxFP_2 605 608 PF00069 0.573
DOC_MAPK_gen_1 103 112 PF00069 0.417
DOC_MAPK_gen_1 163 172 PF00069 0.525
DOC_MAPK_MEF2A_6 103 112 PF00069 0.419
DOC_MAPK_MEF2A_6 255 263 PF00069 0.579
DOC_PP2B_LxvP_1 450 453 PF13499 0.449
DOC_PP4_FxxP_1 263 266 PF00568 0.461
DOC_PP4_FxxP_1 320 323 PF00568 0.541
DOC_PP4_FxxP_1 605 608 PF00568 0.573
DOC_SPAK_OSR1_1 396 400 PF12202 0.385
DOC_USP7_MATH_1 11 15 PF00917 0.663
DOC_USP7_MATH_1 144 148 PF00917 0.391
DOC_USP7_MATH_1 168 172 PF00917 0.327
DOC_USP7_MATH_1 351 355 PF00917 0.333
DOC_USP7_MATH_1 555 559 PF00917 0.653
DOC_USP7_UBL2_3 103 107 PF12436 0.428
DOC_WW_Pin1_4 191 196 PF00397 0.209
DOC_WW_Pin1_4 200 205 PF00397 0.197
DOC_WW_Pin1_4 29 34 PF00397 0.555
DOC_WW_Pin1_4 292 297 PF00397 0.772
DOC_WW_Pin1_4 359 364 PF00397 0.384
DOC_WW_Pin1_4 486 491 PF00397 0.242
DOC_WW_Pin1_4 608 613 PF00397 0.740
DOC_WW_Pin1_4 690 695 PF00397 0.687
LIG_14-3-3_CanoR_1 422 428 PF00244 0.377
LIG_14-3-3_CanoR_1 556 560 PF00244 0.699
LIG_14-3-3_CanoR_1 562 566 PF00244 0.608
LIG_Actin_WH2_2 221 238 PF00022 0.330
LIG_Actin_WH2_2 420 435 PF00022 0.343
LIG_BRCT_BRCA1_1 230 234 PF00533 0.326
LIG_BRCT_BRCA1_1 437 441 PF00533 0.295
LIG_DCNL_PONY_1 1 4 PF03556 0.521
LIG_deltaCOP1_diTrp_1 437 441 PF00928 0.372
LIG_EH1_1 363 371 PF00400 0.263
LIG_FHA_1 171 177 PF00498 0.312
LIG_FHA_1 220 226 PF00498 0.304
LIG_FHA_1 407 413 PF00498 0.368
LIG_FHA_1 46 52 PF00498 0.362
LIG_FHA_1 465 471 PF00498 0.439
LIG_FHA_1 568 574 PF00498 0.703
LIG_FHA_1 584 590 PF00498 0.512
LIG_FHA_1 691 697 PF00498 0.558
LIG_FHA_2 270 276 PF00498 0.524
LIG_FHA_2 614 620 PF00498 0.766
LIG_FHA_2 651 657 PF00498 0.652
LIG_IRF3_LxIS_1 104 111 PF10401 0.385
LIG_LIR_Apic_2 318 323 PF02991 0.511
LIG_LIR_Gen_1 222 230 PF02991 0.262
LIG_LIR_Gen_1 339 350 PF02991 0.360
LIG_LIR_Gen_1 438 448 PF02991 0.292
LIG_LIR_Gen_1 50 61 PF02991 0.321
LIG_LIR_Gen_1 561 569 PF02991 0.632
LIG_LIR_Gen_1 582 592 PF02991 0.622
LIG_LIR_Gen_1 650 658 PF02991 0.684
LIG_LIR_Nem_3 222 226 PF02991 0.319
LIG_LIR_Nem_3 339 345 PF02991 0.345
LIG_LIR_Nem_3 438 444 PF02991 0.281
LIG_LIR_Nem_3 50 56 PF02991 0.450
LIG_LIR_Nem_3 561 566 PF02991 0.682
LIG_LIR_Nem_3 582 587 PF02991 0.622
LIG_LIR_Nem_3 62 66 PF02991 0.321
LIG_LIR_Nem_3 650 654 PF02991 0.763
LIG_NRBOX 138 144 PF00104 0.273
LIG_NRBOX 498 504 PF00104 0.398
LIG_PCNA_APIM_2 249 255 PF02747 0.415
LIG_Pex14_1 36 40 PF04695 0.428
LIG_Pex14_2 316 320 PF04695 0.512
LIG_Pex14_2 342 346 PF04695 0.422
LIG_Pex14_2 479 483 PF04695 0.398
LIG_Pex14_2 565 569 PF04695 0.507
LIG_Pex14_2 59 63 PF04695 0.293
LIG_PTB_Apo_2 378 385 PF02174 0.293
LIG_PTB_Apo_2 599 606 PF02174 0.628
LIG_SH2_CRK 651 655 PF00017 0.690
LIG_SH2_NCK_1 189 193 PF00017 0.285
LIG_SH2_SRC 519 522 PF00017 0.543
LIG_SH2_STAP1 425 429 PF00017 0.253
LIG_SH2_STAP1 651 655 PF00017 0.647
LIG_SH2_STAT5 252 255 PF00017 0.411
LIG_SH2_STAT5 425 428 PF00017 0.207
LIG_SH2_STAT5 498 501 PF00017 0.321
LIG_SH2_STAT5 513 516 PF00017 0.198
LIG_SH2_STAT5 519 522 PF00017 0.424
LIG_SH2_STAT5 66 69 PF00017 0.255
LIG_SH3_3 263 269 PF00018 0.644
LIG_SH3_3 290 296 PF00018 0.718
LIG_SH3_3 407 413 PF00018 0.184
LIG_SH3_3 515 521 PF00018 0.382
LIG_SH3_3 52 58 PF00018 0.388
LIG_SUMO_SIM_anti_2 274 280 PF11976 0.613
LIG_SUMO_SIM_par_1 168 173 PF11976 0.318
LIG_SUMO_SIM_par_1 408 414 PF11976 0.238
LIG_SUMO_SIM_par_1 43 50 PF11976 0.246
LIG_SUMO_SIM_par_1 585 591 PF11976 0.556
LIG_SUMO_SIM_par_1 659 667 PF11976 0.546
LIG_TRAF2_1 638 641 PF00917 0.752
LIG_WRC_WIRS_1 566 571 PF05994 0.519
LIG_WRC_WIRS_1 60 65 PF05994 0.406
MOD_CDK_SPK_2 486 491 PF00069 0.225
MOD_CK1_1 155 161 PF00069 0.530
MOD_CK1_1 203 209 PF00069 0.349
MOD_CK1_1 238 244 PF00069 0.522
MOD_CK1_1 297 303 PF00069 0.655
MOD_CK1_1 486 492 PF00069 0.281
MOD_CK1_1 522 528 PF00069 0.594
MOD_CK1_1 551 557 PF00069 0.717
MOD_CK1_1 558 564 PF00069 0.684
MOD_CK1_1 583 589 PF00069 0.665
MOD_CK1_1 9 15 PF00069 0.623
MOD_CK2_1 269 275 PF00069 0.693
MOD_CK2_1 535 541 PF00069 0.777
MOD_CK2_1 635 641 PF00069 0.762
MOD_Cter_Amidation 104 107 PF01082 0.218
MOD_GlcNHglycan 126 129 PF01048 0.333
MOD_GlcNHglycan 20 24 PF01048 0.375
MOD_GlcNHglycan 240 243 PF01048 0.447
MOD_GlcNHglycan 296 299 PF01048 0.501
MOD_GlcNHglycan 523 527 PF01048 0.436
MOD_GlcNHglycan 550 553 PF01048 0.514
MOD_GlcNHglycan 596 599 PF01048 0.451
MOD_GlcNHglycan 7 11 PF01048 0.387
MOD_GlcNHglycan 73 77 PF01048 0.463
MOD_GlcNHglycan 78 81 PF01048 0.276
MOD_GlcNHglycan 92 95 PF01048 0.232
MOD_GSK3_1 215 222 PF00069 0.209
MOD_GSK3_1 305 312 PF00069 0.694
MOD_GSK3_1 413 420 PF00069 0.316
MOD_GSK3_1 47 54 PF00069 0.271
MOD_GSK3_1 5 12 PF00069 0.714
MOD_GSK3_1 547 554 PF00069 0.718
MOD_GSK3_1 561 568 PF00069 0.500
MOD_GSK3_1 575 582 PF00069 0.656
MOD_GSK3_1 631 638 PF00069 0.755
MOD_GSK3_1 72 79 PF00069 0.317
MOD_N-GLC_1 238 243 PF02516 0.426
MOD_N-GLC_1 636 641 PF02516 0.498
MOD_NEK2_1 108 113 PF00069 0.340
MOD_NEK2_1 124 129 PF00069 0.278
MOD_NEK2_1 157 162 PF00069 0.477
MOD_NEK2_1 235 240 PF00069 0.503
MOD_NEK2_1 423 428 PF00069 0.313
MOD_NEK2_1 446 451 PF00069 0.382
MOD_NEK2_1 47 52 PF00069 0.314
MOD_NEK2_1 483 488 PF00069 0.306
MOD_NEK2_1 501 506 PF00069 0.283
MOD_NEK2_1 514 519 PF00069 0.229
MOD_NEK2_1 565 570 PF00069 0.692
MOD_NEK2_1 579 584 PF00069 0.624
MOD_NEK2_1 96 101 PF00069 0.385
MOD_NEK2_2 175 180 PF00069 0.346
MOD_NEK2_2 555 560 PF00069 0.682
MOD_PIKK_1 398 404 PF00454 0.364
MOD_PIKK_1 636 642 PF00454 0.752
MOD_PIKK_1 9 15 PF00454 0.579
MOD_PKA_1 5 11 PF00069 0.522
MOD_PKA_1 548 554 PF00069 0.542
MOD_PKA_2 235 241 PF00069 0.608
MOD_PKA_2 5 11 PF00069 0.587
MOD_PKA_2 547 553 PF00069 0.681
MOD_PKA_2 555 561 PF00069 0.644
MOD_PKA_2 575 581 PF00069 0.630
MOD_Plk_1 274 280 PF00069 0.671
MOD_Plk_2-3 650 656 PF00069 0.690
MOD_Plk_4 126 132 PF00069 0.340
MOD_Plk_4 144 150 PF00069 0.187
MOD_Plk_4 175 181 PF00069 0.302
MOD_Plk_4 203 209 PF00069 0.293
MOD_Plk_4 215 221 PF00069 0.228
MOD_Plk_4 274 280 PF00069 0.613
MOD_Plk_4 374 380 PF00069 0.384
MOD_Plk_4 383 389 PF00069 0.376
MOD_Plk_4 501 507 PF00069 0.287
MOD_Plk_4 514 520 PF00069 0.211
MOD_Plk_4 535 541 PF00069 0.778
MOD_Plk_4 561 567 PF00069 0.624
MOD_Plk_4 575 581 PF00069 0.679
MOD_Plk_4 59 65 PF00069 0.412
MOD_Plk_4 81 87 PF00069 0.253
MOD_ProDKin_1 191 197 PF00069 0.209
MOD_ProDKin_1 200 206 PF00069 0.197
MOD_ProDKin_1 29 35 PF00069 0.547
MOD_ProDKin_1 292 298 PF00069 0.769
MOD_ProDKin_1 359 365 PF00069 0.384
MOD_ProDKin_1 486 492 PF00069 0.245
MOD_ProDKin_1 608 614 PF00069 0.742
MOD_ProDKin_1 690 696 PF00069 0.687
TRG_DiLeu_BaEn_1 575 580 PF01217 0.592
TRG_DiLeu_BaLyEn_6 320 325 PF01217 0.575
TRG_DiLeu_LyEn_5 659 664 PF01217 0.546
TRG_ENDOCYTIC_2 223 226 PF00928 0.307
TRG_ENDOCYTIC_2 405 408 PF00928 0.400
TRG_ENDOCYTIC_2 498 501 PF00928 0.353
TRG_ENDOCYTIC_2 563 566 PF00928 0.680
TRG_ENDOCYTIC_2 651 654 PF00928 0.694
TRG_ER_diArg_1 325 327 PF00400 0.532
TRG_ER_diArg_1 4 6 PF00400 0.525
TRG_ER_diArg_1 559 562 PF00400 0.677
TRG_ER_diArg_1 625 627 PF00400 0.609
TRG_NES_CRM1_1 38 49 PF08389 0.443
TRG_Pf-PMV_PEXEL_1 243 247 PF00026 0.396
TRG_Pf-PMV_PEXEL_1 626 630 PF00026 0.418

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IBQ3 Leptomonas seymouri 39% 100%
A0A0N1PGE0 Leptomonas seymouri 55% 100%
A0A1X0P5R5 Trypanosomatidae 32% 100%
A0A286LF01 Psilocybe cyanescens 25% 100%
A0A3R7KR66 Trypanosoma rangeli 32% 100%
A0A3S7X9E2 Leishmania donovani 86% 100%
A4HMU4 Leishmania braziliensis 63% 100%
A4IBE5 Leishmania infantum 86% 100%
C9ZZ72 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
E9AFA2 Leishmania major 83% 100%
P0DPB2 Psilocybe cubensis 26% 100%
V5BTI8 Trypanosoma cruzi 34% 100%
V5C2Z8 Trypanosoma cruzi 31% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS