LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

SET domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
SET domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B6F1_LEIMU
TriTrypDb:
LmxM.34.2725
Length:
771

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6F1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6F1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 196 200 PF00656 0.586
CLV_C14_Caspase3-7 274 278 PF00656 0.569
CLV_C14_Caspase3-7 345 349 PF00656 0.579
CLV_NRD_NRD_1 225 227 PF00675 0.706
CLV_NRD_NRD_1 247 249 PF00675 0.627
CLV_NRD_NRD_1 298 300 PF00675 0.583
CLV_NRD_NRD_1 421 423 PF00675 0.518
CLV_NRD_NRD_1 446 448 PF00675 0.484
CLV_NRD_NRD_1 451 453 PF00675 0.488
CLV_NRD_NRD_1 584 586 PF00675 0.587
CLV_NRD_NRD_1 66 68 PF00675 0.693
CLV_PCSK_FUR_1 443 447 PF00082 0.510
CLV_PCSK_KEX2_1 224 226 PF00082 0.716
CLV_PCSK_KEX2_1 247 249 PF00082 0.627
CLV_PCSK_KEX2_1 298 300 PF00082 0.583
CLV_PCSK_KEX2_1 421 423 PF00082 0.518
CLV_PCSK_KEX2_1 445 447 PF00082 0.504
CLV_PCSK_KEX2_1 714 716 PF00082 0.623
CLV_PCSK_PC1ET2_1 224 226 PF00082 0.716
CLV_PCSK_PC1ET2_1 714 716 PF00082 0.623
CLV_PCSK_PC7_1 243 249 PF00082 0.594
CLV_PCSK_SKI1_1 202 206 PF00082 0.649
CLV_PCSK_SKI1_1 339 343 PF00082 0.523
CLV_PCSK_SKI1_1 35 39 PF00082 0.450
CLV_PCSK_SKI1_1 379 383 PF00082 0.439
CLV_PCSK_SKI1_1 447 451 PF00082 0.505
CLV_PCSK_SKI1_1 453 457 PF00082 0.494
CLV_PCSK_SKI1_1 504 508 PF00082 0.773
CLV_PCSK_SKI1_1 57 61 PF00082 0.647
CLV_PCSK_SKI1_1 621 625 PF00082 0.702
CLV_PCSK_SKI1_1 635 639 PF00082 0.562
CLV_PCSK_SKI1_1 715 719 PF00082 0.599
DEG_APCC_KENBOX_2 109 113 PF00400 0.724
DEG_Nend_Nbox_1 1 3 PF02207 0.565
DEG_SPOP_SBC_1 128 132 PF00917 0.721
DEG_SPOP_SBC_1 204 208 PF00917 0.637
DEG_SPOP_SBC_1 211 215 PF00917 0.645
DOC_CKS1_1 488 493 PF01111 0.675
DOC_MAPK_gen_1 317 326 PF00069 0.431
DOC_MAPK_gen_1 33 40 PF00069 0.593
DOC_MAPK_HePTP_8 314 326 PF00069 0.328
DOC_MAPK_MEF2A_6 317 326 PF00069 0.431
DOC_PP1_RVXF_1 577 584 PF00149 0.580
DOC_PP1_RVXF_1 91 98 PF00149 0.530
DOC_PP2B_LxvP_1 38 41 PF13499 0.703
DOC_PP2B_LxvP_1 59 62 PF13499 0.650
DOC_PP2B_LxvP_1 637 640 PF13499 0.707
DOC_PP2B_LxvP_1 657 660 PF13499 0.360
DOC_PP2B_LxvP_1 766 769 PF13499 0.520
DOC_PP4_FxxP_1 147 150 PF00568 0.589
DOC_PP4_FxxP_1 658 661 PF00568 0.587
DOC_USP7_MATH_1 117 121 PF00917 0.736
DOC_USP7_MATH_1 128 132 PF00917 0.671
DOC_USP7_MATH_1 211 215 PF00917 0.806
DOC_USP7_MATH_1 217 221 PF00917 0.703
DOC_USP7_MATH_1 231 235 PF00917 0.528
DOC_USP7_MATH_1 375 379 PF00917 0.505
DOC_USP7_MATH_1 502 506 PF00917 0.572
DOC_USP7_MATH_1 62 66 PF00917 0.674
DOC_USP7_MATH_2 491 497 PF00917 0.681
DOC_WW_Pin1_4 122 127 PF00397 0.766
DOC_WW_Pin1_4 166 171 PF00397 0.685
DOC_WW_Pin1_4 254 259 PF00397 0.604
DOC_WW_Pin1_4 371 376 PF00397 0.474
DOC_WW_Pin1_4 487 492 PF00397 0.675
DOC_WW_Pin1_4 621 626 PF00397 0.626
DOC_WW_Pin1_4 733 738 PF00397 0.780
DOC_WW_Pin1_4 739 744 PF00397 0.686
DOC_WW_Pin1_4 95 100 PF00397 0.541
LIG_14-3-3_CanoR_1 119 128 PF00244 0.768
LIG_14-3-3_CanoR_1 16 23 PF00244 0.626
LIG_14-3-3_CanoR_1 57 62 PF00244 0.653
LIG_APCC_ABBA_1 380 385 PF00400 0.465
LIG_APCC_ABBAyCdc20_2 379 385 PF00400 0.440
LIG_APCC_ABBAyCdc20_2 540 546 PF00400 0.600
LIG_BRCT_BRCA1_1 434 438 PF00533 0.570
LIG_CaM_IQ_9 608 623 PF13499 0.664
LIG_Clathr_ClatBox_1 749 753 PF01394 0.518
LIG_CtBP_PxDLS_1 218 224 PF00389 0.685
LIG_FHA_1 141 147 PF00498 0.717
LIG_FHA_1 175 181 PF00498 0.720
LIG_FHA_1 205 211 PF00498 0.649
LIG_FHA_1 23 29 PF00498 0.697
LIG_FHA_1 230 236 PF00498 0.563
LIG_FHA_1 462 468 PF00498 0.462
LIG_FHA_1 49 55 PF00498 0.677
LIG_FHA_1 516 522 PF00498 0.434
LIG_FHA_1 58 64 PF00498 0.602
LIG_FHA_1 612 618 PF00498 0.545
LIG_FHA_1 634 640 PF00498 0.609
LIG_FHA_1 704 710 PF00498 0.608
LIG_FHA_2 184 190 PF00498 0.563
LIG_FHA_2 40 46 PF00498 0.709
LIG_FHA_2 488 494 PF00498 0.677
LIG_FHA_2 554 560 PF00498 0.550
LIG_FHA_2 641 647 PF00498 0.686
LIG_FHA_2 666 672 PF00498 0.489
LIG_FHA_2 89 95 PF00498 0.764
LIG_LIR_Apic_2 655 661 PF02991 0.567
LIG_LIR_Apic_2 739 743 PF02991 0.527
LIG_LIR_Gen_1 435 444 PF02991 0.560
LIG_LIR_Gen_1 546 553 PF02991 0.616
LIG_LIR_Gen_1 671 681 PF02991 0.542
LIG_LIR_Nem_3 310 314 PF02991 0.518
LIG_LIR_Nem_3 405 411 PF02991 0.438
LIG_LIR_Nem_3 435 441 PF02991 0.541
LIG_LIR_Nem_3 546 550 PF02991 0.610
LIG_LIR_Nem_3 668 673 PF02991 0.530
LIG_LIR_Nem_3 708 713 PF02991 0.649
LIG_LYPXL_yS_3 311 314 PF13949 0.521
LIG_LYPXL_yS_3 408 411 PF13949 0.313
LIG_NRBOX 435 441 PF00104 0.566
LIG_SH2_CRK 173 177 PF00017 0.716
LIG_SH2_SRC 645 648 PF00017 0.550
LIG_SH2_STAP1 355 359 PF00017 0.454
LIG_SH2_STAP1 645 649 PF00017 0.546
LIG_SH2_STAP1 670 674 PF00017 0.524
LIG_SH2_STAT3 690 693 PF00017 0.413
LIG_SH2_STAT5 428 431 PF00017 0.491
LIG_SH2_STAT5 454 457 PF00017 0.492
LIG_SH2_STAT5 610 613 PF00017 0.575
LIG_SH2_STAT5 673 676 PF00017 0.527
LIG_SH3_3 149 155 PF00018 0.792
LIG_SH3_3 17 23 PF00018 0.581
LIG_SH3_3 243 249 PF00018 0.769
LIG_SH3_3 250 256 PF00018 0.820
LIG_SH3_3 485 491 PF00018 0.529
LIG_SH3_3 658 664 PF00018 0.594
LIG_SH3_3 725 731 PF00018 0.692
LIG_SH3_3 74 80 PF00018 0.463
LIG_SH3_3 740 746 PF00018 0.612
LIG_SUMO_SIM_anti_2 747 753 PF11976 0.614
LIG_SUMO_SIM_par_1 322 330 PF11976 0.467
LIG_SUMO_SIM_par_1 36 43 PF11976 0.461
LIG_SUMO_SIM_par_1 747 753 PF11976 0.614
LIG_TRAF2_1 736 739 PF00917 0.683
LIG_UBA3_1 580 586 PF00899 0.583
MOD_CDK_SPK_2 122 127 PF00069 0.559
MOD_CDK_SPK_2 166 171 PF00069 0.560
MOD_CDK_SPxxK_3 487 494 PF00069 0.677
MOD_CDK_SPxxK_3 621 628 PF00069 0.627
MOD_CK1_1 122 128 PF00069 0.718
MOD_CK1_1 140 146 PF00069 0.684
MOD_CK1_1 36 42 PF00069 0.668
MOD_CK1_1 487 493 PF00069 0.676
MOD_CK1_1 589 595 PF00069 0.565
MOD_CK1_1 666 672 PF00069 0.538
MOD_CK1_1 691 697 PF00069 0.457
MOD_CK2_1 128 134 PF00069 0.721
MOD_CK2_1 224 230 PF00069 0.632
MOD_CK2_1 371 377 PF00069 0.597
MOD_CK2_1 487 493 PF00069 0.676
MOD_CK2_1 553 559 PF00069 0.581
MOD_CK2_1 665 671 PF00069 0.495
MOD_CK2_1 733 739 PF00069 0.781
MOD_CK2_1 83 89 PF00069 0.635
MOD_GlcNHglycan 147 150 PF01048 0.842
MOD_GlcNHglycan 17 20 PF01048 0.570
MOD_GlcNHglycan 214 217 PF01048 0.752
MOD_GlcNHglycan 273 276 PF01048 0.761
MOD_GlcNHglycan 495 498 PF01048 0.705
MOD_GlcNHglycan 503 507 PF01048 0.635
MOD_GlcNHglycan 526 529 PF01048 0.627
MOD_GlcNHglycan 690 693 PF01048 0.578
MOD_GlcNHglycan 70 73 PF01048 0.676
MOD_GlcNHglycan 85 88 PF01048 0.640
MOD_GlcNHglycan 9 12 PF01048 0.641
MOD_GSK3_1 115 122 PF00069 0.751
MOD_GSK3_1 129 136 PF00069 0.791
MOD_GSK3_1 205 212 PF00069 0.831
MOD_GSK3_1 271 278 PF00069 0.718
MOD_GSK3_1 371 378 PF00069 0.646
MOD_GSK3_1 385 392 PF00069 0.457
MOD_GSK3_1 463 470 PF00069 0.669
MOD_GSK3_1 471 478 PF00069 0.648
MOD_GSK3_1 502 509 PF00069 0.624
MOD_GSK3_1 57 64 PF00069 0.657
MOD_GSK3_1 665 672 PF00069 0.488
MOD_GSK3_1 684 691 PF00069 0.516
MOD_N-GLC_1 137 142 PF02516 0.729
MOD_N-GLC_1 560 565 PF02516 0.621
MOD_N-GLC_2 575 577 PF02516 0.408
MOD_NEK2_1 121 126 PF00069 0.645
MOD_NEK2_1 133 138 PF00069 0.797
MOD_NEK2_1 205 210 PF00069 0.783
MOD_NEK2_1 238 243 PF00069 0.554
MOD_NEK2_1 271 276 PF00069 0.708
MOD_NEK2_1 291 296 PF00069 0.562
MOD_NEK2_1 369 374 PF00069 0.425
MOD_NEK2_1 389 394 PF00069 0.488
MOD_NEK2_1 467 472 PF00069 0.727
MOD_NEK2_1 517 522 PF00069 0.675
MOD_NEK2_1 524 529 PF00069 0.547
MOD_NEK2_1 553 558 PF00069 0.640
MOD_NEK2_1 758 763 PF00069 0.501
MOD_NEK2_2 62 67 PF00069 0.680
MOD_NEK2_2 640 645 PF00069 0.585
MOD_NEK2_2 88 93 PF00069 0.505
MOD_PIKK_1 137 143 PF00454 0.818
MOD_PK_1 224 230 PF00069 0.532
MOD_PKA_1 224 230 PF00069 0.648
MOD_PKA_1 247 253 PF00069 0.579
MOD_PKA_1 298 304 PF00069 0.587
MOD_PKA_2 134 140 PF00069 0.739
MOD_PKA_2 15 21 PF00069 0.607
MOD_PKA_2 224 230 PF00069 0.648
MOD_PKA_2 247 253 PF00069 0.579
MOD_PKA_2 298 304 PF00069 0.587
MOD_PKA_2 389 395 PF00069 0.492
MOD_PKA_2 461 467 PF00069 0.550
MOD_Plk_1 350 356 PF00069 0.474
MOD_Plk_1 424 430 PF00069 0.481
MOD_Plk_1 515 521 PF00069 0.611
MOD_Plk_1 560 566 PF00069 0.468
MOD_Plk_1 645 651 PF00069 0.549
MOD_Plk_1 759 765 PF00069 0.606
MOD_Plk_1 88 94 PF00069 0.611
MOD_Plk_4 217 223 PF00069 0.785
MOD_Plk_4 298 304 PF00069 0.585
MOD_Plk_4 560 566 PF00069 0.468
MOD_Plk_4 589 595 PF00069 0.590
MOD_Plk_4 633 639 PF00069 0.652
MOD_Plk_4 640 646 PF00069 0.584
MOD_Plk_4 669 675 PF00069 0.526
MOD_Plk_4 753 759 PF00069 0.501
MOD_ProDKin_1 122 128 PF00069 0.765
MOD_ProDKin_1 166 172 PF00069 0.683
MOD_ProDKin_1 254 260 PF00069 0.605
MOD_ProDKin_1 371 377 PF00069 0.471
MOD_ProDKin_1 487 493 PF00069 0.676
MOD_ProDKin_1 621 627 PF00069 0.623
MOD_ProDKin_1 733 739 PF00069 0.781
MOD_ProDKin_1 95 101 PF00069 0.543
MOD_SUMO_rev_2 185 192 PF00179 0.805
MOD_SUMO_rev_2 316 322 PF00179 0.488
MOD_SUMO_rev_2 39 48 PF00179 0.706
TRG_Cilium_Arf4_1 767 771 PF00025 0.670
TRG_DiLeu_BaEn_1 747 752 PF01217 0.615
TRG_DiLeu_BaEn_2 450 456 PF01217 0.327
TRG_DiLeu_BaEn_4 424 430 PF01217 0.560
TRG_DiLeu_BaLyEn_6 576 581 PF01217 0.583
TRG_ENDOCYTIC_2 173 176 PF00928 0.563
TRG_ENDOCYTIC_2 311 314 PF00928 0.521
TRG_ENDOCYTIC_2 383 386 PF00928 0.467
TRG_ENDOCYTIC_2 408 411 PF00928 0.491
TRG_ENDOCYTIC_2 673 676 PF00928 0.532
TRG_ER_diArg_1 246 248 PF00400 0.624
TRG_ER_diArg_1 420 422 PF00400 0.499
TRG_ER_diArg_1 445 447 PF00400 0.488
TRG_NES_CRM1_1 541 555 PF08389 0.560
TRG_Pf-PMV_PEXEL_1 226 230 PF00026 0.677
TRG_Pf-PMV_PEXEL_1 447 451 PF00026 0.584
TRG_Pf-PMV_PEXEL_1 537 541 PF00026 0.629
TRG_Pf-PMV_PEXEL_1 701 705 PF00026 0.556

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PGC9 Leptomonas seymouri 55% 97%
A0A3Q8IIE1 Leishmania donovani 83% 100%
A4HMT9 Leishmania braziliensis 68% 98%
A4IBE0 Leishmania infantum 83% 100%
E9AF96 Leishmania major 51% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS