Ubiquitin-like domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B6D9_LEIMU

TriTrypDb:

LmxM.34.2610

Length:

326

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B6D9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6D9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	109	111	PF00675	0.765
CLV_NRD_NRD_1	151	153	PF00675	0.599
CLV_NRD_NRD_1	192	194	PF00675	0.693
CLV_NRD_NRD_1	210	212	PF00675	0.497
CLV_NRD_NRD_1	270	272	PF00675	0.474
CLV_NRD_NRD_1	36	38	PF00675	0.662
CLV_NRD_NRD_1	8	10	PF00675	0.640
CLV_PCSK_FUR_1	33	37	PF00082	0.602
CLV_PCSK_FUR_1	6	10	PF00082	0.646
CLV_PCSK_KEX2_1	103	105	PF00082	0.818
CLV_PCSK_KEX2_1	209	211	PF00082	0.751
CLV_PCSK_KEX2_1	269	271	PF00082	0.475
CLV_PCSK_KEX2_1	35	37	PF00082	0.687
CLV_PCSK_KEX2_1	8	10	PF00082	0.640
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.726
CLV_PCSK_PC1ET2_1	269	271	PF00082	0.475
CLV_PCSK_PC1ET2_1	35	37	PF00082	0.650
CLV_PCSK_SKI1_1	142	146	PF00082	0.612
CLV_PCSK_SKI1_1	202	206	PF00082	0.550
CLV_PCSK_SKI1_1	270	274	PF00082	0.583
CLV_PCSK_SKI1_1	41	45	PF00082	0.713
CLV_PCSK_SKI1_1	77	81	PF00082	0.627
DEG_APCC_DBOX_1	269	277	PF00400	0.485
DEG_Nend_UBRbox_1	1	4	PF02207	0.697
DOC_CDC14_PxL_1	288	296	PF14671	0.468
DOC_CKS1_1	224	229	PF01111	0.647
DOC_CKS1_1	83	88	PF01111	0.675
DOC_CKS1_1	91	96	PF01111	0.608
DOC_MAPK_gen_1	193	199	PF00069	0.519
DOC_MAPK_gen_1	269	275	PF00069	0.476
DOC_MAPK_MEF2A_6	269	277	PF00069	0.485
DOC_PP4_FxxP_1	322	325	PF00568	0.551
DOC_USP7_MATH_1	118	122	PF00917	0.740
DOC_USP7_MATH_1	161	165	PF00917	0.592
DOC_USP7_MATH_1	175	179	PF00917	0.644
DOC_USP7_MATH_1	234	238	PF00917	0.462
DOC_USP7_MATH_1	258	262	PF00917	0.484
DOC_USP7_MATH_1	46	50	PF00917	0.597
DOC_USP7_MATH_1	56	60	PF00917	0.597
DOC_USP7_MATH_1	68	72	PF00917	0.666
DOC_USP7_UBL2_3	138	142	PF12436	0.723
DOC_USP7_UBL2_3	182	186	PF12436	0.575
DOC_USP7_UBL2_3	35	39	PF12436	0.668
DOC_USP7_UBL2_3	57	61	PF12436	0.683
DOC_WW_Pin1_4	110	115	PF00397	0.624
DOC_WW_Pin1_4	132	137	PF00397	0.663
DOC_WW_Pin1_4	153	158	PF00397	0.530
DOC_WW_Pin1_4	223	228	PF00397	0.643
DOC_WW_Pin1_4	41	46	PF00397	0.714
DOC_WW_Pin1_4	82	87	PF00397	0.701
DOC_WW_Pin1_4	90	95	PF00397	0.751
LIG_14-3-3_CanoR_1	108	114	PF00244	0.713
LIG_14-3-3_CanoR_1	193	199	PF00244	0.694
LIG_14-3-3_CanoR_1	256	266	PF00244	0.439
LIG_14-3-3_CanoR_1	312	320	PF00244	0.446
LIG_14-3-3_CanoR_1	8	16	PF00244	0.583
LIG_EVH1_1	188	192	PF00568	0.503
LIG_FHA_1	193	199	PF00498	0.688
LIG_FHA_1	224	230	PF00498	0.653
LIG_FHA_1	303	309	PF00498	0.507
LIG_FHA_2	64	70	PF00498	0.550
LIG_Integrin_isoDGR_2	297	299	PF01839	0.554
LIG_LIR_Apic_2	317	323	PF02991	0.478
LIG_RPA_C_Fungi	204	216	PF08784	0.580
LIG_SH2_STAT5	14	17	PF00017	0.617
LIG_SH2_STAT5	28	31	PF00017	0.445
LIG_SH2_STAT5	320	323	PF00017	0.497
LIG_SH3_1	103	109	PF00018	0.561
LIG_SH3_1	186	192	PF00018	0.558
LIG_SH3_1	215	221	PF00018	0.619
LIG_SH3_1	80	86	PF00018	0.638
LIG_SH3_1	88	94	PF00018	0.617
LIG_SH3_2	106	111	PF14604	0.594
LIG_SH3_2	189	194	PF14604	0.674
LIG_SH3_2	83	88	PF14604	0.716
LIG_SH3_3	103	109	PF00018	0.579
LIG_SH3_3	155	161	PF00018	0.525
LIG_SH3_3	181	187	PF00018	0.705
LIG_SH3_3	215	221	PF00018	0.776
LIG_SH3_3	272	278	PF00018	0.465
LIG_SH3_3	286	292	PF00018	0.449
LIG_SH3_3	45	51	PF00018	0.692
LIG_SH3_3	80	86	PF00018	0.699
LIG_SH3_3	88	94	PF00018	0.654
LIG_SH3_5	10	14	PF00018	0.510
LIG_UBA3_1	264	269	PF00899	0.279
MOD_CDK_SPxK_1	132	138	PF00069	0.665
MOD_CDK_SPxK_1	82	88	PF00069	0.675
MOD_CDK_SPxxK_3	153	160	PF00069	0.528
MOD_CDK_SPxxK_3	90	97	PF00069	0.585
MOD_CK1_1	237	243	PF00069	0.448
MOD_CK1_1	314	320	PF00069	0.445
MOD_CK1_1	72	78	PF00069	0.639
MOD_CK2_1	63	69	PF00069	0.548
MOD_GlcNHglycan	177	180	PF01048	0.651
MOD_GlcNHglycan	239	242	PF01048	0.417
MOD_GlcNHglycan	281	284	PF01048	0.587
MOD_GlcNHglycan	313	316	PF01048	0.461
MOD_GSK3_1	246	253	PF00069	0.486
MOD_GSK3_1	311	318	PF00069	0.450
MOD_GSK3_1	56	63	PF00069	0.652
MOD_GSK3_1	68	75	PF00069	0.585
MOD_N-GLC_1	250	255	PF02516	0.503
MOD_NEK2_1	246	251	PF00069	0.506
MOD_NEK2_2	315	320	PF00069	0.441
MOD_PIKK_1	69	75	PF00454	0.606
MOD_PKA_1	35	41	PF00069	0.666
MOD_PKA_1	61	67	PF00069	0.666
MOD_PKA_2	109	115	PF00069	0.715
MOD_PKA_2	192	198	PF00069	0.693
MOD_PKA_2	311	317	PF00069	0.452
MOD_PKA_2	35	41	PF00069	0.669
MOD_PKB_1	146	154	PF00069	0.568
MOD_Plk_1	234	240	PF00069	0.575
MOD_Plk_1	315	321	PF00069	0.435
MOD_Plk_4	200	206	PF00069	0.686
MOD_Plk_4	260	266	PF00069	0.312
MOD_Plk_4	284	290	PF00069	0.543
MOD_Plk_4	315	321	PF00069	0.483
MOD_ProDKin_1	110	116	PF00069	0.628
MOD_ProDKin_1	132	138	PF00069	0.665
MOD_ProDKin_1	153	159	PF00069	0.529
MOD_ProDKin_1	223	229	PF00069	0.647
MOD_ProDKin_1	41	47	PF00069	0.715
MOD_ProDKin_1	82	88	PF00069	0.704
MOD_ProDKin_1	90	96	PF00069	0.752
TRG_ER_diArg_1	149	152	PF00400	0.549
TRG_ER_diArg_1	209	211	PF00400	0.694
TRG_ER_diArg_1	270	272	PF00400	0.474
TRG_ER_diArg_1	8	11	PF00400	0.598
TRG_NLS_MonoExtC_3	268	274	PF00514	0.463
TRG_NLS_MonoExtC_3	34	39	PF00514	0.615
TRG_NLS_MonoExtN_4	33	39	PF00514	0.608
TRG_Pf-PMV_PEXEL_1	270	274	PF00026	0.481
TRG_Pf-PMV_PEXEL_1	299	304	PF00026	0.517

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IF70	Leishmania donovani	87%	100%
A4HMT0	Leishmania braziliensis	61%	90%
A4IBC8	Leishmania infantum	87%	100%
E9AF84	Leishmania major	86%	100%