Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B6C3_LEIMU

TriTrypDb:

LmxM.34.2430

Length:

513

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9B6C3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B6C3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	13	17	PF00656	0.617
CLV_C14_Caspase3-7	274	278	PF00656	0.796
CLV_C14_Caspase3-7	369	373	PF00656	0.811
CLV_C14_Caspase3-7	379	383	PF00656	0.648
CLV_C14_Caspase3-7	454	458	PF00656	0.597
CLV_NRD_NRD_1	303	305	PF00675	0.687
CLV_NRD_NRD_1	321	323	PF00675	0.676
CLV_NRD_NRD_1	37	39	PF00675	0.786
CLV_PCSK_KEX2_1	269	271	PF00082	0.658
CLV_PCSK_KEX2_1	37	39	PF00082	0.786
CLV_PCSK_PC1ET2_1	269	271	PF00082	0.658
CLV_PCSK_SKI1_1	251	255	PF00082	0.793
CLV_PCSK_SKI1_1	492	496	PF00082	0.559
CLV_PCSK_SKI1_1	500	504	PF00082	0.571
DEG_Nend_UBRbox_3	1	3	PF02207	0.765
DEG_SCF_FBW7_1	430	436	PF00400	0.816
DEG_SCF_FBW7_2	397	402	PF00400	0.818
DOC_CKS1_1	430	435	PF01111	0.812
DOC_MAPK_MEF2A_6	482	489	PF00069	0.531
DOC_MAPK_RevD_3	485	500	PF00069	0.508
DOC_PP2B_LxvP_1	242	245	PF13499	0.577
DOC_PP2B_LxvP_1	339	342	PF13499	0.796
DOC_PP4_FxxP_1	222	225	PF00568	0.588
DOC_USP7_MATH_1	102	106	PF00917	0.689
DOC_USP7_MATH_1	184	188	PF00917	0.705
DOC_USP7_MATH_1	227	231	PF00917	0.606
DOC_USP7_MATH_1	297	301	PF00917	0.598
DOC_USP7_MATH_1	342	346	PF00917	0.737
DOC_USP7_MATH_1	417	421	PF00917	0.798
DOC_USP7_MATH_1	422	426	PF00917	0.710
DOC_USP7_MATH_1	481	485	PF00917	0.606
DOC_USP7_UBL2_3	301	305	PF12436	0.647
DOC_WW_Pin1_4	128	133	PF00397	0.776
DOC_WW_Pin1_4	232	237	PF00397	0.742
DOC_WW_Pin1_4	321	326	PF00397	0.768
DOC_WW_Pin1_4	349	354	PF00397	0.671
DOC_WW_Pin1_4	395	400	PF00397	0.708
DOC_WW_Pin1_4	407	412	PF00397	0.738
DOC_WW_Pin1_4	429	434	PF00397	0.694
DOC_WW_Pin1_4	442	447	PF00397	0.688
DOC_WW_Pin1_4	466	471	PF00397	0.758
LIG_14-3-3_CanoR_1	117	123	PF00244	0.650
LIG_14-3-3_CanoR_1	304	314	PF00244	0.682
LIG_14-3-3_CanoR_1	387	392	PF00244	0.601
LIG_14-3-3_CanoR_1	482	488	PF00244	0.531
LIG_AP2alpha_2	191	193	PF02296	0.590
LIG_BRCT_BRCA1_1	382	386	PF00533	0.822
LIG_CtBP_PxDLS_1	263	269	PF00389	0.599
LIG_FHA_1	136	142	PF00498	0.664
LIG_FHA_1	245	251	PF00498	0.747
LIG_FHA_1	255	261	PF00498	0.511
LIG_FHA_1	322	328	PF00498	0.726
LIG_FHA_1	336	342	PF00498	0.592
LIG_FHA_1	353	359	PF00498	0.809
LIG_FHA_1	396	402	PF00498	0.766
LIG_FHA_1	430	436	PF00498	0.816
LIG_FHA_1	491	497	PF00498	0.709
LIG_FHA_1	507	513	PF00498	0.604
LIG_FHA_1	76	82	PF00498	0.676
LIG_FHA_2	117	123	PF00498	0.825
LIG_FHA_2	377	383	PF00498	0.615
LIG_FHA_2	452	458	PF00498	0.601
LIG_Integrin_RGD_1	73	75	PF01839	0.764
LIG_LIR_Apic_2	218	224	PF02991	0.685
LIG_LIR_Apic_2	308	314	PF02991	0.671
LIG_LIR_Apic_2	498	504	PF02991	0.737
LIG_LIR_Nem_3	313	318	PF02991	0.615
LIG_LIR_Nem_3	52	58	PF02991	0.606
LIG_LYPXL_yS_3	55	58	PF13949	0.605
LIG_MYND_1	317	321	PF01753	0.672
LIG_Pex14_1	475	479	PF04695	0.584
LIG_Pex14_2	83	87	PF04695	0.793
LIG_SH2_CRK	243	247	PF00017	0.571
LIG_SH2_STAT5	221	224	PF00017	0.612
LIG_SH2_STAT5	311	314	PF00017	0.784
LIG_SH2_STAT5	479	482	PF00017	0.566
LIG_SH2_STAT5	71	74	PF00017	0.562
LIG_SH3_1	311	317	PF00018	0.672
LIG_SH3_3	129	135	PF00018	0.829
LIG_SH3_3	197	203	PF00018	0.780
LIG_SH3_3	243	249	PF00018	0.664
LIG_SH3_3	283	289	PF00018	0.795
LIG_SH3_3	311	317	PF00018	0.672
LIG_SH3_3	330	336	PF00018	0.685
LIG_SH3_3	427	433	PF00018	0.688
LIG_SH3_3	434	440	PF00018	0.710
LIG_SH3_3	475	481	PF00018	0.771
LIG_SH3_3	50	56	PF00018	0.743
LIG_SUMO_SIM_par_1	432	438	PF11976	0.616
LIG_SUMO_SIM_par_1	490	498	PF11976	0.624
LIG_TRAF2_1	403	406	PF00917	0.830
LIG_TRAF2_1	488	491	PF00917	0.608
LIG_TYR_ITIM	53	58	PF00017	0.606
MOD_CK1_1	118	124	PF00069	0.723
MOD_CK1_1	128	134	PF00069	0.684
MOD_CK1_1	14	20	PF00069	0.726
MOD_CK1_1	146	152	PF00069	0.738
MOD_CK1_1	214	220	PF00069	0.736
MOD_CK1_1	29	35	PF00069	0.652
MOD_CK1_1	337	343	PF00069	0.795
MOD_CK1_1	352	358	PF00069	0.597
MOD_CK1_1	373	379	PF00069	0.780
MOD_CK1_1	390	396	PF00069	0.544
MOD_CK2_1	214	220	PF00069	0.736
MOD_CK2_1	223	229	PF00069	0.650
MOD_CK2_1	25	31	PF00069	0.792
MOD_CK2_1	303	309	PF00069	0.587
MOD_CK2_1	400	406	PF00069	0.728
MOD_CK2_1	485	491	PF00069	0.609
MOD_GlcNHglycan	109	112	PF01048	0.684
MOD_GlcNHglycan	122	126	PF01048	0.641
MOD_GlcNHglycan	145	148	PF01048	0.739
MOD_GlcNHglycan	16	19	PF01048	0.633
MOD_GlcNHglycan	225	228	PF01048	0.738
MOD_GlcNHglycan	372	375	PF01048	0.707
MOD_GlcNHglycan	394	397	PF01048	0.710
MOD_GSK3_1	121	128	PF00069	0.761
MOD_GSK3_1	135	142	PF00069	0.709
MOD_GSK3_1	198	205	PF00069	0.682
MOD_GSK3_1	207	214	PF00069	0.610
MOD_GSK3_1	223	230	PF00069	0.692
MOD_GSK3_1	25	32	PF00069	0.751
MOD_GSK3_1	254	261	PF00069	0.616
MOD_GSK3_1	299	306	PF00069	0.720
MOD_GSK3_1	331	338	PF00069	0.764
MOD_GSK3_1	376	383	PF00069	0.736
MOD_GSK3_1	386	393	PF00069	0.628
MOD_GSK3_1	429	436	PF00069	0.761
MOD_GSK3_1	442	449	PF00069	0.613
MOD_GSK3_1	481	488	PF00069	0.619
MOD_N-GLC_1	100	105	PF02516	0.541
MOD_N-GLC_1	376	381	PF02516	0.782
MOD_N-GLC_1	422	427	PF02516	0.796
MOD_N-GLC_1	83	88	PF02516	0.774
MOD_NEK2_1	115	120	PF00069	0.598
MOD_NEK2_1	158	163	PF00069	0.758
MOD_NEK2_1	208	213	PF00069	0.799
MOD_NEK2_1	303	308	PF00069	0.589
MOD_NEK2_1	386	391	PF00069	0.815
MOD_NEK2_1	412	417	PF00069	0.739
MOD_NEK2_1	495	500	PF00069	0.713
MOD_NEK2_2	299	304	PF00069	0.596
MOD_OFUCOSY	30	35	PF10250	0.557
MOD_PIKK_1	102	108	PF00454	0.684
MOD_PIKK_1	198	204	PF00454	0.795
MOD_PKA_1	37	43	PF00069	0.789
MOD_PKA_2	116	122	PF00069	0.820
MOD_PKA_2	303	309	PF00069	0.756
MOD_PKA_2	37	43	PF00069	0.789
MOD_PKA_2	386	392	PF00069	0.603
MOD_PKA_2	481	487	PF00069	0.541
MOD_Plk_1	158	164	PF00069	0.566
MOD_Plk_1	184	190	PF00069	0.810
MOD_Plk_1	380	386	PF00069	0.612
MOD_Plk_1	422	428	PF00069	0.712
MOD_Plk_1	490	496	PF00069	0.594
MOD_Plk_1	83	89	PF00069	0.789
MOD_Plk_4	211	217	PF00069	0.786
MOD_Plk_4	342	348	PF00069	0.725
MOD_Plk_4	387	393	PF00069	0.810
MOD_ProDKin_1	128	134	PF00069	0.775
MOD_ProDKin_1	232	238	PF00069	0.740
MOD_ProDKin_1	321	327	PF00069	0.770
MOD_ProDKin_1	349	355	PF00069	0.668
MOD_ProDKin_1	395	401	PF00069	0.709
MOD_ProDKin_1	407	413	PF00069	0.738
MOD_ProDKin_1	429	435	PF00069	0.697
MOD_ProDKin_1	442	448	PF00069	0.692
MOD_ProDKin_1	466	472	PF00069	0.760
MOD_SUMO_rev_2	425	433	PF00179	0.800
TRG_DiLeu_BaEn_1	490	495	PF01217	0.594
TRG_DiLeu_BaLyEn_6	501	506	PF01217	0.633
TRG_ENDOCYTIC_2	243	246	PF00928	0.574
TRG_ENDOCYTIC_2	55	58	PF00928	0.605
TRG_NLS_MonoExtC_3	303	309	PF00514	0.797
TRG_NLS_MonoExtN_4	301	308	PF00514	0.606
TRG_Pf-PMV_PEXEL_1	186	190	PF00026	0.808
TRG_Pf-PMV_PEXEL_1	269	273	PF00026	0.605

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFH2	Leptomonas seymouri	28%	69%
A4IBF3	Leishmania infantum	80%	100%