Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B691_LEIMU

TriTrypDb:

LmxM.34.2125

Length:

282

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B691

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B691

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	243	245	PF00675	0.478
CLV_PCSK_KEX2_1	243	245	PF00082	0.478
CLV_PCSK_KEX2_1	256	258	PF00082	0.560
CLV_PCSK_PC1ET2_1	256	258	PF00082	0.560
CLV_PCSK_SKI1_1	256	260	PF00082	0.519
DOC_MAPK_MEF2A_6	102	109	PF00069	0.512
DOC_PP2B_LxvP_1	164	167	PF13499	0.522
DOC_PP2B_LxvP_1	264	267	PF13499	0.607
DOC_USP7_MATH_1	118	122	PF00917	0.644
DOC_USP7_MATH_1	124	128	PF00917	0.642
DOC_USP7_MATH_1	181	185	PF00917	0.658
DOC_USP7_UBL2_3	273	277	PF12436	0.411
DOC_WW_Pin1_4	144	149	PF00397	0.815
DOC_WW_Pin1_4	159	164	PF00397	0.598
DOC_WW_Pin1_4	176	181	PF00397	0.657
DOC_WW_Pin1_4	197	202	PF00397	0.682
LIG_14-3-3_CanoR_1	192	198	PF00244	0.797
LIG_14-3-3_CanoR_1	60	66	PF00244	0.671
LIG_BIR_II_1	1	5	PF00653	0.718
LIG_BRCT_BRCA1_1	113	117	PF00533	0.699
LIG_BRCT_BRCA1_1	62	66	PF00533	0.670
LIG_FHA_1	219	225	PF00498	0.767
LIG_FHA_2	3	9	PF00498	0.722
LIG_FHA_2	49	55	PF00498	0.528
LIG_LIR_Nem_3	135	140	PF02991	0.798
LIG_PTAP_UEV_1	152	157	PF05743	0.655
LIG_SH2_CRK	262	266	PF00017	0.721
LIG_SH2_STAP1	262	266	PF00017	0.590
LIG_SH3_3	145	151	PF00018	0.689
LIG_SH3_3	164	170	PF00018	0.744
LIG_SH3_3	195	201	PF00018	0.716
LIG_SUMO_SIM_par_1	104	111	PF11976	0.510
LIG_TRAF2_1	187	190	PF00917	0.808
LIG_TRAF2_1	26	29	PF00917	0.770
LIG_TRAF2_1	51	54	PF00917	0.592
LIG_TRAF2_1	77	80	PF00917	0.763
MOD_CK1_1	113	119	PF00069	0.774
MOD_CK1_1	132	138	PF00069	0.681
MOD_CK1_1	175	181	PF00069	0.751
MOD_CK1_1	2	8	PF00069	0.728
MOD_CK1_1	62	68	PF00069	0.741
MOD_CK2_1	23	29	PF00069	0.665
MOD_CK2_1	235	241	PF00069	0.745
MOD_CK2_1	48	54	PF00069	0.524
MOD_GlcNHglycan	113	116	PF01048	0.695
MOD_GlcNHglycan	122	125	PF01048	0.711
MOD_GlcNHglycan	131	134	PF01048	0.739
MOD_GlcNHglycan	174	177	PF01048	0.770
MOD_GlcNHglycan	208	211	PF01048	0.760
MOD_GlcNHglycan	25	28	PF01048	0.613
MOD_GlcNHglycan	93	96	PF01048	0.680
MOD_GSK3_1	120	127	PF00069	0.727
MOD_GSK3_1	140	147	PF00069	0.770
MOD_GSK3_1	172	179	PF00069	0.694
MOD_GSK3_1	19	26	PF00069	0.649
MOD_GSK3_1	193	200	PF00069	0.733
MOD_GSK3_1	55	62	PF00069	0.730
MOD_NEK2_1	1	6	PF00069	0.741
MOD_NEK2_1	217	222	PF00069	0.733
MOD_NEK2_1	229	234	PF00069	0.488
MOD_PIKK_1	2	8	PF00454	0.611
MOD_PIKK_1	48	54	PF00454	0.601
MOD_PKA_2	2	8	PF00069	0.514
MOD_PKA_2	59	65	PF00069	0.822
MOD_Plk_1	229	235	PF00069	0.746
MOD_Plk_4	154	160	PF00069	0.727
MOD_ProDKin_1	144	150	PF00069	0.809
MOD_ProDKin_1	159	165	PF00069	0.598
MOD_ProDKin_1	176	182	PF00069	0.657
MOD_ProDKin_1	197	203	PF00069	0.682
MOD_SUMO_for_1	101	104	PF00179	0.735
MOD_SUMO_rev_2	250	258	PF00179	0.603
MOD_SUMO_rev_2	94	103	PF00179	0.796
TRG_ENDOCYTIC_2	262	265	PF00928	0.617
TRG_ER_diArg_1	242	244	PF00400	0.461
TRG_Pf-PMV_PEXEL_1	231	235	PF00026	0.745

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1P934	Leptomonas seymouri	32%	85%
A0A3Q8IPH3	Leishmania donovani	76%	100%
A4HMN4	Leishmania braziliensis	61%	98%
E9AF36	Leishmania major	80%	96%
E9AHV3	Leishmania infantum	76%	100%