LeishMANIAdb
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Putative calcium motive P-type ATPase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative calcium motive P-type ATPase
Gene product:
calcium motive p-type ATPase, putative
Species:
Leishmania mexicana
UniProt:
E9B686_LEIMU
TriTrypDb:
LmxM.34.2080
Length:
1225

Annotations

LeishMANIAdb annotations

Homologous to animal ER-localized Ca2+ ATPases. Localization: ER (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. no yes: 12
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 5
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0016020 membrane 2 12
GO:0110165 cellular anatomical entity 1 12
GO:0005886 plasma membrane 3 1

Expansion

Sequence features

E9B686
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B686

Function

Biological processes
Term Name Level Count
GO:0006810 transport 3 1
GO:0006811 monoatomic ion transport 4 1
GO:0006812 monoatomic cation transport 5 1
GO:0006816 calcium ion transport 7 1
GO:0006873 intracellular monoatomic ion homeostasis 4 1
GO:0006874 intracellular calcium ion homeostasis 7 1
GO:0006875 obsolete intracellular metal ion homeostasis 6 1
GO:0009987 cellular process 1 1
GO:0019725 cellular homeostasis 2 1
GO:0030001 metal ion transport 6 1
GO:0030003 intracellular monoatomic cation homeostasis 5 1
GO:0034220 monoatomic ion transmembrane transport 3 1
GO:0042592 homeostatic process 3 1
GO:0048878 chemical homeostasis 4 1
GO:0050801 monoatomic ion homeostasis 5 1
GO:0051179 localization 1 1
GO:0051234 establishment of localization 2 1
GO:0055065 obsolete metal ion homeostasis 7 1
GO:0055074 calcium ion homeostasis 8 1
GO:0055080 monoatomic cation homeostasis 6 1
GO:0055082 intracellular chemical homeostasis 3 1
GO:0055085 transmembrane transport 2 1
GO:0065007 biological regulation 1 1
GO:0065008 regulation of biological quality 2 1
GO:0070588 calcium ion transmembrane transport 6 1
GO:0072503 obsolete cellular divalent inorganic cation homeostasis 6 1
GO:0072507 obsolete divalent inorganic cation homeostasis 7 1
GO:0098655 monoatomic cation transmembrane transport 4 1
GO:0098660 inorganic ion transmembrane transport 4 1
GO:0098662 inorganic cation transmembrane transport 5 1
GO:0098771 inorganic ion homeostasis 6 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 12
GO:0003824 catalytic activity 1 12
GO:0005488 binding 1 12
GO:0005524 ATP binding 5 12
GO:0016462 pyrophosphatase activity 5 12
GO:0016787 hydrolase activity 2 12
GO:0016817 hydrolase activity, acting on acid anhydrides 3 12
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 12
GO:0016887 ATP hydrolysis activity 7 12
GO:0017076 purine nucleotide binding 4 12
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 12
GO:0030554 adenyl nucleotide binding 5 12
GO:0032553 ribonucleotide binding 3 12
GO:0032555 purine ribonucleotide binding 4 12
GO:0032559 adenyl ribonucleotide binding 5 12
GO:0035639 purine ribonucleoside triphosphate binding 4 12
GO:0036094 small molecule binding 2 12
GO:0043167 ion binding 2 12
GO:0043168 anion binding 3 12
GO:0097159 organic cyclic compound binding 2 12
GO:0097367 carbohydrate derivative binding 2 12
GO:1901265 nucleoside phosphate binding 3 12
GO:1901363 heterocyclic compound binding 2 12
GO:0005215 transporter activity 1 2
GO:0005388 P-type calcium transporter activity 4 1
GO:0008324 monoatomic cation transmembrane transporter activity 4 2
GO:0015075 monoatomic ion transmembrane transporter activity 3 2
GO:0015085 calcium ion transmembrane transporter activity 6 1
GO:0015318 inorganic molecular entity transmembrane transporter activity 3 2
GO:0015399 primary active transmembrane transporter activity 4 2
GO:0015662 P-type ion transporter activity 4 1
GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3 2
GO:0022804 active transmembrane transporter activity 3 2
GO:0022853 active monoatomic ion transmembrane transporter activity 4 2
GO:0022857 transmembrane transporter activity 2 2
GO:0022890 inorganic cation transmembrane transporter activity 4 2
GO:0042626 ATPase-coupled transmembrane transporter activity 2 2
GO:0046873 metal ion transmembrane transporter activity 5 1
GO:0140358 P-type transmembrane transporter activity 3 1
GO:0140657 ATP-dependent activity 1 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 222 226 PF00656 0.499
CLV_C14_Caspase3-7 232 236 PF00656 0.437
CLV_C14_Caspase3-7 605 609 PF00656 0.522
CLV_C14_Caspase3-7 825 829 PF00656 0.482
CLV_NRD_NRD_1 1143 1145 PF00675 0.359
CLV_NRD_NRD_1 1221 1223 PF00675 0.491
CLV_NRD_NRD_1 388 390 PF00675 0.224
CLV_NRD_NRD_1 436 438 PF00675 0.211
CLV_NRD_NRD_1 507 509 PF00675 0.271
CLV_NRD_NRD_1 804 806 PF00675 0.317
CLV_NRD_NRD_1 854 856 PF00675 0.239
CLV_NRD_NRD_1 912 914 PF00675 0.237
CLV_NRD_NRD_1 918 920 PF00675 0.246
CLV_PCSK_KEX2_1 1216 1218 PF00082 0.438
CLV_PCSK_KEX2_1 1223 1225 PF00082 0.467
CLV_PCSK_KEX2_1 123 125 PF00082 0.348
CLV_PCSK_KEX2_1 422 424 PF00082 0.317
CLV_PCSK_KEX2_1 498 500 PF00082 0.239
CLV_PCSK_KEX2_1 653 655 PF00082 0.215
CLV_PCSK_KEX2_1 803 805 PF00082 0.285
CLV_PCSK_KEX2_1 854 856 PF00082 0.225
CLV_PCSK_KEX2_1 912 914 PF00082 0.237
CLV_PCSK_PC1ET2_1 1216 1218 PF00082 0.476
CLV_PCSK_PC1ET2_1 1223 1225 PF00082 0.493
CLV_PCSK_PC1ET2_1 123 125 PF00082 0.348
CLV_PCSK_PC1ET2_1 422 424 PF00082 0.317
CLV_PCSK_PC1ET2_1 498 500 PF00082 0.257
CLV_PCSK_PC1ET2_1 653 655 PF00082 0.215
CLV_PCSK_SKI1_1 1080 1084 PF00082 0.282
CLV_PCSK_SKI1_1 1134 1138 PF00082 0.262
CLV_PCSK_SKI1_1 1144 1148 PF00082 0.331
CLV_PCSK_SKI1_1 307 311 PF00082 0.215
CLV_PCSK_SKI1_1 383 387 PF00082 0.317
CLV_PCSK_SKI1_1 419 423 PF00082 0.305
CLV_PCSK_SKI1_1 432 436 PF00082 0.300
CLV_PCSK_SKI1_1 782 786 PF00082 0.215
DEG_APCC_DBOX_1 1143 1151 PF00400 0.559
DOC_ANK_TNKS_1 156 163 PF00023 0.667
DOC_CYCLIN_yCln2_LP_2 1092 1098 PF00134 0.266
DOC_CYCLIN_yCln2_LP_2 807 813 PF00134 0.517
DOC_MAPK_DCC_7 318 326 PF00069 0.517
DOC_MAPK_gen_1 1144 1150 PF00069 0.561
DOC_MAPK_gen_1 197 205 PF00069 0.558
DOC_MAPK_gen_1 437 445 PF00069 0.476
DOC_MAPK_gen_1 508 515 PF00069 0.465
DOC_MAPK_gen_1 538 544 PF00069 0.439
DOC_MAPK_gen_1 662 669 PF00069 0.472
DOC_MAPK_gen_1 919 925 PF00069 0.425
DOC_MAPK_MEF2A_6 113 121 PF00069 0.558
DOC_MAPK_MEF2A_6 255 264 PF00069 0.395
DOC_MAPK_MEF2A_6 318 326 PF00069 0.439
DOC_MAPK_MEF2A_6 508 515 PF00069 0.568
DOC_PP1_RVXF_1 1135 1142 PF00149 0.580
DOC_PP1_RVXF_1 714 721 PF00149 0.453
DOC_PP2B_LxvP_1 1092 1095 PF13499 0.340
DOC_PP2B_LxvP_1 982 985 PF13499 0.425
DOC_PP2B_PxIxI_1 869 875 PF00149 0.439
DOC_PP4_FxxP_1 1206 1209 PF00568 0.728
DOC_PP4_FxxP_1 730 733 PF00568 0.425
DOC_USP7_MATH_1 1067 1071 PF00917 0.482
DOC_USP7_MATH_1 299 303 PF00917 0.500
DOC_USP7_MATH_1 593 597 PF00917 0.443
DOC_USP7_MATH_1 80 84 PF00917 0.597
DOC_USP7_MATH_1 880 884 PF00917 0.475
DOC_USP7_MATH_1 92 96 PF00917 0.677
DOC_USP7_UBL2_3 428 432 PF12436 0.517
DOC_USP7_UBL2_3 534 538 PF12436 0.425
DOC_WW_Pin1_4 187 192 PF00397 0.669
DOC_WW_Pin1_4 32 37 PF00397 0.608
DOC_WW_Pin1_4 463 468 PF00397 0.317
DOC_WW_Pin1_4 838 843 PF00397 0.415
DOC_WW_Pin1_4 866 871 PF00397 0.425
DOC_WW_Pin1_4 950 955 PF00397 0.251
LIG_14-3-3_CanoR_1 1046 1054 PF00244 0.229
LIG_14-3-3_CanoR_1 1188 1192 PF00244 0.588
LIG_14-3-3_CanoR_1 124 128 PF00244 0.548
LIG_14-3-3_CanoR_1 301 307 PF00244 0.529
LIG_14-3-3_CanoR_1 56 64 PF00244 0.637
LIG_14-3-3_CanoR_1 79 85 PF00244 0.574
LIG_14-3-3_CanoR_1 912 921 PF00244 0.442
LIG_14-3-3_CanoR_1 976 984 PF00244 0.440
LIG_Actin_WH2_2 1175 1190 PF00022 0.583
LIG_Actin_WH2_2 703 718 PF00022 0.415
LIG_BIR_II_1 1 5 PF00653 0.590
LIG_BRCT_BRCA1_1 1046 1050 PF00533 0.267
LIG_BRCT_BRCA1_1 1089 1093 PF00533 0.251
LIG_BRCT_BRCA1_1 268 272 PF00533 0.306
LIG_Clathr_ClatBox_1 1147 1151 PF01394 0.642
LIG_Clathr_ClatBox_1 211 215 PF01394 0.439
LIG_CtBP_PxDLS_1 573 577 PF00389 0.422
LIG_deltaCOP1_diTrp_1 1040 1050 PF00928 0.227
LIG_deltaCOP1_diTrp_1 1078 1083 PF00928 0.415
LIG_deltaCOP1_diTrp_1 274 278 PF00928 0.293
LIG_deltaCOP1_diTrp_1 956 963 PF00928 0.285
LIG_eIF4E_1 441 447 PF01652 0.439
LIG_FAT_LD_1 439 447 PF03623 0.425
LIG_FHA_1 1130 1136 PF00498 0.451
LIG_FHA_1 257 263 PF00498 0.266
LIG_FHA_1 308 314 PF00498 0.488
LIG_FHA_1 492 498 PF00498 0.419
LIG_FHA_1 52 58 PF00498 0.686
LIG_FHA_1 525 531 PF00498 0.425
LIG_FHA_1 595 601 PF00498 0.448
LIG_FHA_1 681 687 PF00498 0.494
LIG_FHA_1 886 892 PF00498 0.489
LIG_FHA_1 976 982 PF00498 0.452
LIG_FHA_1 991 997 PF00498 0.366
LIG_FHA_2 1170 1176 PF00498 0.686
LIG_FHA_2 527 533 PF00498 0.425
LIG_FHA_2 555 561 PF00498 0.503
LIG_FHA_2 655 661 PF00498 0.517
LIG_FHA_2 694 700 PF00498 0.423
LIG_GBD_Chelix_1 409 417 PF00786 0.282
LIG_Integrin_isoDGR_2 155 157 PF01839 0.470
LIG_IRF3_LxIS_1 936 943 PF10401 0.453
LIG_LIR_Apic_2 1203 1209 PF02991 0.722
LIG_LIR_Apic_2 727 733 PF02991 0.461
LIG_LIR_Gen_1 1165 1174 PF02991 0.680
LIG_LIR_Gen_1 1190 1199 PF02991 0.647
LIG_LIR_Gen_1 206 217 PF02991 0.475
LIG_LIR_Gen_1 245 254 PF02991 0.519
LIG_LIR_Gen_1 274 283 PF02991 0.227
LIG_LIR_Gen_1 637 648 PF02991 0.427
LIG_LIR_Gen_1 818 827 PF02991 0.433
LIG_LIR_Gen_1 828 837 PF02991 0.416
LIG_LIR_Gen_1 898 909 PF02991 0.448
LIG_LIR_Gen_1 956 967 PF02991 0.266
LIG_LIR_Nem_3 1047 1053 PF02991 0.255
LIG_LIR_Nem_3 1090 1096 PF02991 0.201
LIG_LIR_Nem_3 1113 1119 PF02991 0.225
LIG_LIR_Nem_3 1131 1136 PF02991 0.266
LIG_LIR_Nem_3 1165 1169 PF02991 0.578
LIG_LIR_Nem_3 1190 1194 PF02991 0.620
LIG_LIR_Nem_3 198 203 PF02991 0.504
LIG_LIR_Nem_3 206 212 PF02991 0.429
LIG_LIR_Nem_3 245 249 PF02991 0.519
LIG_LIR_Nem_3 274 278 PF02991 0.294
LIG_LIR_Nem_3 440 444 PF02991 0.468
LIG_LIR_Nem_3 637 643 PF02991 0.427
LIG_LIR_Nem_3 750 756 PF02991 0.435
LIG_LIR_Nem_3 818 822 PF02991 0.433
LIG_LIR_Nem_3 828 833 PF02991 0.416
LIG_LIR_Nem_3 898 904 PF02991 0.446
LIG_LIR_Nem_3 988 994 PF02991 0.465
LIG_MYND_3 510 514 PF01753 0.564
LIG_Pex14_1 959 963 PF04695 0.266
LIG_Pex14_2 1072 1076 PF04695 0.418
LIG_Pex14_2 283 287 PF04695 0.251
LIG_PTB_Apo_2 1135 1142 PF02174 0.488
LIG_REV1ctd_RIR_1 1218 1225 PF16727 0.544
LIG_RPA_C_Fungi 1041 1053 PF08784 0.285
LIG_SH2_CRK 1133 1137 PF00017 0.266
LIG_SH2_CRK 586 590 PF00017 0.224
LIG_SH2_CRK 760 764 PF00017 0.266
LIG_SH2_GRB2like 1098 1101 PF00017 0.395
LIG_SH2_NCK_1 465 469 PF00017 0.324
LIG_SH2_SRC 1098 1101 PF00017 0.285
LIG_SH2_SRC 760 763 PF00017 0.266
LIG_SH2_STAP1 472 476 PF00017 0.251
LIG_SH2_STAT3 34 37 PF00017 0.483
LIG_SH2_STAT3 584 587 PF00017 0.286
LIG_SH2_STAT5 1054 1057 PF00017 0.251
LIG_SH2_STAT5 1062 1065 PF00017 0.251
LIG_SH2_STAT5 1098 1101 PF00017 0.251
LIG_SH2_STAT5 34 37 PF00017 0.483
LIG_SH2_STAT5 444 447 PF00017 0.269
LIG_SH2_STAT5 465 468 PF00017 0.395
LIG_SH2_STAT5 584 587 PF00017 0.395
LIG_SH2_STAT5 668 671 PF00017 0.266
LIG_SH3_3 1061 1067 PF00018 0.285
LIG_SH3_3 759 765 PF00018 0.266
LIG_SUMO_SIM_anti_2 245 252 PF11976 0.395
LIG_SUMO_SIM_anti_2 259 265 PF11976 0.273
LIG_SUMO_SIM_anti_2 334 339 PF11976 0.278
LIG_SUMO_SIM_anti_2 932 938 PF11976 0.252
LIG_SUMO_SIM_anti_2 953 959 PF11976 0.266
LIG_SUMO_SIM_anti_2 993 1000 PF11976 0.378
LIG_SUMO_SIM_par_1 100 105 PF11976 0.484
LIG_SUMO_SIM_par_1 1146 1154 PF11976 0.544
LIG_SUMO_SIM_par_1 245 252 PF11976 0.395
LIG_SUMO_SIM_par_1 263 269 PF11976 0.301
LIG_SUMO_SIM_par_1 334 339 PF11976 0.287
LIG_SUMO_SIM_par_1 676 683 PF11976 0.285
LIG_SUMO_SIM_par_1 691 696 PF11976 0.285
LIG_TRFH_1 950 954 PF08558 0.251
LIG_TYR_ITIM 1052 1057 PF00017 0.251
LIG_UBA3_1 1139 1145 PF00899 0.548
LIG_UBA3_1 247 255 PF00899 0.274
LIG_UBA3_1 848 857 PF00899 0.266
LIG_WRC_WIRS_1 1123 1128 PF05994 0.286
LIG_WRC_WIRS_1 1166 1171 PF05994 0.610
LIG_WRC_WIRS_1 14 19 PF05994 0.529
LIG_WW_3 761 765 PF00397 0.251
MOD_CDK_SPxxK_3 838 845 PF00069 0.251
MOD_CDK_SPxxK_3 866 873 PF00069 0.266
MOD_CK1_1 1110 1116 PF00069 0.286
MOD_CK1_1 1190 1196 PF00069 0.494
MOD_CK1_1 1197 1203 PF00069 0.519
MOD_CK1_1 302 308 PF00069 0.381
MOD_CK1_1 427 433 PF00069 0.320
MOD_CK1_1 471 477 PF00069 0.277
MOD_CK1_1 524 530 PF00069 0.251
MOD_CK1_1 58 64 PF00069 0.519
MOD_CK1_1 647 653 PF00069 0.286
MOD_CK1_1 767 773 PF00069 0.266
MOD_CK1_1 794 800 PF00069 0.345
MOD_CK1_1 841 847 PF00069 0.251
MOD_CK2_1 1021 1027 PF00069 0.286
MOD_CK2_1 526 532 PF00069 0.283
MOD_CK2_1 654 660 PF00069 0.395
MOD_CK2_1 950 956 PF00069 0.266
MOD_Cter_Amidation 910 913 PF01082 0.283
MOD_GlcNHglycan 1 4 PF01048 0.501
MOD_GlcNHglycan 1023 1026 PF01048 0.341
MOD_GlcNHglycan 104 107 PF01048 0.712
MOD_GlcNHglycan 128 131 PF01048 0.575
MOD_GlcNHglycan 149 152 PF01048 0.761
MOD_GlcNHglycan 268 271 PF01048 0.266
MOD_GlcNHglycan 429 432 PF01048 0.298
MOD_GlcNHglycan 73 76 PF01048 0.551
MOD_GlcNHglycan 882 885 PF01048 0.369
MOD_GlcNHglycan 964 967 PF01048 0.285
MOD_GSK3_1 102 109 PF00069 0.703
MOD_GSK3_1 1041 1048 PF00069 0.441
MOD_GSK3_1 1165 1172 PF00069 0.609
MOD_GSK3_1 119 126 PF00069 0.737
MOD_GSK3_1 1190 1197 PF00069 0.509
MOD_GSK3_1 13 20 PF00069 0.676
MOD_GSK3_1 147 154 PF00069 0.648
MOD_GSK3_1 160 167 PF00069 0.515
MOD_GSK3_1 24 31 PF00069 0.460
MOD_GSK3_1 32 39 PF00069 0.523
MOD_GSK3_1 393 400 PF00069 0.242
MOD_GSK3_1 422 429 PF00069 0.267
MOD_GSK3_1 487 494 PF00069 0.284
MOD_GSK3_1 51 58 PF00069 0.549
MOD_GSK3_1 517 524 PF00069 0.291
MOD_GSK3_1 65 72 PF00069 0.532
MOD_GSK3_1 680 687 PF00069 0.287
MOD_GSK3_1 782 789 PF00069 0.355
MOD_N-GLC_1 517 522 PF02516 0.307
MOD_N-GLC_1 69 74 PF02516 0.535
MOD_N-GLC_1 866 871 PF02516 0.251
MOD_NEK2_1 1058 1063 PF00069 0.310
MOD_NEK2_1 1107 1112 PF00069 0.295
MOD_NEK2_1 1169 1174 PF00069 0.620
MOD_NEK2_1 1187 1192 PF00069 0.478
MOD_NEK2_1 17 22 PF00069 0.502
MOD_NEK2_1 424 429 PF00069 0.467
MOD_NEK2_1 493 498 PF00069 0.251
MOD_NEK2_1 594 599 PF00069 0.265
MOD_NEK2_1 848 853 PF00069 0.389
MOD_NEK2_1 925 930 PF00069 0.266
MOD_NEK2_1 962 967 PF00069 0.266
MOD_NEK2_2 1067 1072 PF00069 0.345
MOD_NEK2_2 945 950 PF00069 0.403
MOD_PIKK_1 17 23 PF00454 0.492
MOD_PIKK_1 249 255 PF00454 0.395
MOD_PIKK_1 394 400 PF00454 0.276
MOD_PIKK_1 693 699 PF00454 0.395
MOD_PIKK_1 912 918 PF00454 0.304
MOD_PIKK_1 985 991 PF00454 0.286
MOD_PKA_1 1215 1221 PF00069 0.520
MOD_PKA_1 123 129 PF00069 0.512
MOD_PKA_1 422 428 PF00069 0.229
MOD_PKA_1 653 659 PF00069 0.251
MOD_PKA_1 912 918 PF00069 0.304
MOD_PKA_2 1045 1051 PF00069 0.248
MOD_PKA_2 1067 1073 PF00069 0.255
MOD_PKA_2 1187 1193 PF00069 0.491
MOD_PKA_2 123 129 PF00069 0.437
MOD_PKA_2 394 400 PF00069 0.251
MOD_PKA_2 422 428 PF00069 0.284
MOD_PKA_2 55 61 PF00069 0.526
MOD_PKA_2 653 659 PF00069 0.280
MOD_PKA_2 767 773 PF00069 0.345
MOD_PKA_2 78 84 PF00069 0.516
MOD_PKA_2 912 918 PF00069 0.304
MOD_PKA_2 975 981 PF00069 0.286
MOD_Plk_1 299 305 PF00069 0.369
MOD_Plk_1 58 64 PF00069 0.507
MOD_Plk_1 644 650 PF00069 0.395
MOD_Plk_2-3 823 829 PF00069 0.297
MOD_Plk_2-3 975 981 PF00069 0.395
MOD_Plk_4 1067 1073 PF00069 0.251
MOD_Plk_4 1087 1093 PF00069 0.124
MOD_Plk_4 1122 1128 PF00069 0.183
MOD_Plk_4 123 129 PF00069 0.473
MOD_Plk_4 242 248 PF00069 0.395
MOD_Plk_4 595 601 PF00069 0.291
MOD_Plk_4 767 773 PF00069 0.305
MOD_Plk_4 794 800 PF00069 0.345
MOD_Plk_4 900 906 PF00069 0.294
MOD_Plk_4 945 951 PF00069 0.381
MOD_Plk_4 997 1003 PF00069 0.283
MOD_ProDKin_1 187 193 PF00069 0.599
MOD_ProDKin_1 32 38 PF00069 0.521
MOD_ProDKin_1 463 469 PF00069 0.395
MOD_ProDKin_1 838 844 PF00069 0.251
MOD_ProDKin_1 866 872 PF00069 0.266
MOD_ProDKin_1 950 956 PF00069 0.251
MOD_SUMO_for_1 663 666 PF00179 0.286
MOD_SUMO_rev_2 425 430 PF00179 0.186
MOD_SUMO_rev_2 645 652 PF00179 0.266
MOD_SUMO_rev_2 656 663 PF00179 0.266
MOD_SUMO_rev_2 687 693 PF00179 0.418
MOD_SUMO_rev_2 841 846 PF00179 0.251
TRG_DiLeu_BaEn_1 688 693 PF01217 0.395
TRG_DiLeu_BaEn_1 932 937 PF01217 0.251
TRG_ENDOCYTIC_2 1054 1057 PF00928 0.251
TRG_ENDOCYTIC_2 1133 1136 PF00928 0.266
TRG_ENDOCYTIC_2 1166 1169 PF00928 0.474
TRG_ENDOCYTIC_2 14 17 PF00928 0.532
TRG_ENDOCYTIC_2 444 447 PF00928 0.266
TRG_ENDOCYTIC_2 586 589 PF00928 0.305
TRG_ER_diArg_1 1072 1075 PF00400 0.324
TRG_ER_diArg_1 1221 1224 PF00400 0.696
TRG_ER_diArg_1 802 805 PF00400 0.324
TRG_ER_diArg_1 912 914 PF00400 0.282
TRG_NES_CRM1_1 323 334 PF08389 0.345
TRG_NES_CRM1_1 750 761 PF08389 0.270
TRG_NLS_MonoCore_2 1213 1218 PF00514 0.566
TRG_NLS_MonoExtN_4 1214 1219 PF00514 0.602
TRG_NLS_MonoExtN_4 854 859 PF00514 0.310
TRG_Pf-PMV_PEXEL_1 1145 1149 PF00026 0.560
TRG_Pf-PMV_PEXEL_1 135 139 PF00026 0.585
TRG_Pf-PMV_PEXEL_1 157 161 PF00026 0.609
TRG_Pf-PMV_PEXEL_1 583 587 PF00026 0.288
TRG_Pf-PMV_PEXEL_1 782 787 PF00026 0.251
TRG_Pf-PMV_PEXEL_1 805 809 PF00026 0.395
TRG_Pf-PMV_PEXEL_1 912 916 PF00026 0.308

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3Y1 Leptomonas seymouri 31% 100%
A0A0N1HWG6 Leptomonas seymouri 28% 100%
A0A0N1PFH3 Leptomonas seymouri 73% 100%
A0A0S4J5A1 Bodo saltans 51% 100%
A0A0S4JA92 Bodo saltans 27% 100%
A0A0S4KIG5 Bodo saltans 32% 100%
A0A0S4KNQ6 Bodo saltans 27% 100%
A0A1X0NNY6 Trypanosomatidae 30% 100%
A0A1X0P689 Trypanosomatidae 69% 100%
A0A381MFJ0 Leishmania infantum 27% 100%
A0A3R7MRX8 Trypanosoma rangeli 63% 100%
A0A3S5H5Y9 Leishmania donovani 25% 100%
A0A3S5ISK9 Trypanosoma rangeli 25% 100%
A0A3S7WPW0 Leishmania donovani 25% 100%
A0A3S7WV61 Leishmania donovani 27% 100%
A0A3S7WV68 Leishmania donovani 27% 100%
A0A3S7X978 Leishmania donovani 96% 100%
A0A422NTS7 Trypanosoma rangeli 30% 100%
A0A451EJU6 Leishmania donovani 31% 100%
A4H3S2 Leishmania braziliensis 31% 100%
A4H514 Leishmania braziliensis 27% 100%
A4H903 Leishmania braziliensis 29% 100%
A4H9Q5 Leishmania braziliensis 27% 100%
A4HMM8 Leishmania braziliensis 89% 100%
A4HRZ6 Leishmania infantum 31% 100%
A4HT82 Leishmania infantum 27% 100%
A4HTF0 Leishmania infantum 26% 100%
A4HY23 Leishmania infantum 27% 100%
A4IBA6 Leishmania infantum 96% 100%
A7L9Z8 Mus musculus 28% 100%
C9ZPL1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZUN6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 100%
C9ZZN4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 63% 100%
E9AF31 Leishmania major 95% 100%
E9AJY3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 31% 100%
E9AL76 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
E9AL78 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 100%
E9ART6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
J9VQQ3 Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) 27% 87%
O14983 Homo sapiens 30% 100%
O22218 Arabidopsis thaliana 27% 100%
O23087 Arabidopsis thaliana 32% 100%
O34431 Bacillus subtilis (strain 168) 34% 100%
O43108 Yarrowia lipolytica (strain CLIB 122 / E 150) 31% 100%
O46674 Canis lupus familiaris 30% 100%
O55143 Mus musculus 30% 100%
O59868 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 31% 100%
O64806 Arabidopsis thaliana 27% 100%
O70228 Mus musculus 22% 100%
O75110 Homo sapiens 22% 100%
O75185 Homo sapiens 29% 100%
O77696 Sus scrofa 31% 100%
O94296 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 23% 97%
P04191 Oryctolagus cuniculus 30% 100%
P05025 Tetronarce californica 30% 100%
P11507 Rattus norvegicus 30% 100%
P11607 Sus scrofa 30% 100%
P13585 Gallus gallus 30% 100%
P13586 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 28% 100%
P13587 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 35% 100%
P13607 Drosophila melanogaster 29% 100%
P16615 Homo sapiens 30% 100%
P17326 Artemia franciscana 28% 100%
P18596 Rattus norvegicus 31% 100%
P20647 Oryctolagus cuniculus 30% 100%
P22189 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 38% 100%
P22700 Drosophila melanogaster 31% 100%
P28774 Artemia franciscana 29% 100%
P30714 Rhinella marina 29% 100%
P35315 Trypanosoma brucei brucei 31% 100%
P35316 Artemia franciscana 28% 100%
P37278 Synechococcus elongatus (strain PCC 7942 / FACHB-805) 35% 100%
P54209 Dunaliella bioculata 30% 100%
P54210 Dunaliella acidophila 24% 100%
P54679 Dictyostelium discoideum 26% 100%
P54707 Homo sapiens 28% 100%
P57709 Bos taurus 29% 100%
P63688 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 30% 100%
P70083 Makaira nigricans 31% 100%
P70704 Mus musculus 23% 100%
P92939 Arabidopsis thaliana 31% 100%
P98194 Homo sapiens 30% 100%
P9WPS8 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 30% 100%
P9WPS9 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 30% 100%
Q00779 Felis catus 30% 100%
Q01896 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 35% 100%
Q03669 Gallus gallus 29% 100%
Q0VCY0 Bos taurus 30% 100%
Q12691 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 35% 100%
Q292Q0 Drosophila pseudoobscura pseudoobscura 30% 100%
Q29449 Bos taurus 23% 100%
Q2QY12 Oryza sativa subsp. japonica 28% 100%
Q2RAS0 Oryza sativa subsp. japonica 26% 100%
Q42883 Solanum lycopersicum 31% 100%
Q4QDN7 Leishmania major 27% 100%
Q4QDN8 Leishmania major 27% 100%
Q4QIM6 Leishmania major 27% 100%
Q4QIM8 Leishmania major 27% 100%
Q5R5K5 Pongo abelii 30% 100%
Q64518 Mus musculus 31% 100%
Q64541 Rattus norvegicus 28% 100%
Q64566 Rattus norvegicus 30% 100%
Q64578 Rattus norvegicus 30% 100%
Q6RWA9 Taenia solium 29% 100%
Q73E41 Bacillus cereus (strain ATCC 10987 / NRS 248) 33% 100%
Q7PPA5 Anopheles gambiae 30% 100%
Q7X8B5 Oryza sativa subsp. japonica 27% 100%
Q80XR2 Mus musculus 30% 100%
Q8R429 Mus musculus 30% 100%
Q8R4C1 Rattus norvegicus 29% 100%
Q8Y8Q5 Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) 30% 100%
Q92036 Rhinella marina 29% 100%
Q92105 Pelophylax lessonae 30% 100%
Q92126 Xenopus laevis 26% 100%
Q93084 Homo sapiens 32% 100%
Q95Z93 Leishmania major 31% 100%
Q9CFU9 Lactococcus lactis subsp. lactis (strain IL1403) 29% 100%
Q9CTG6 Mus musculus 21% 100%
Q9HDW7 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 28% 95%
Q9LF79 Arabidopsis thaliana 31% 100%
Q9M2L4 Arabidopsis thaliana 26% 100%
Q9SY55 Arabidopsis thaliana 31% 100%
Q9TV52 Oryctolagus cuniculus 29% 100%
Q9XES1 Arabidopsis thaliana 32% 100%
Q9YGL9 Gallus gallus 30% 100%
V5B873 Trypanosoma cruzi 26% 100%
V5BHZ2 Trypanosoma cruzi 67% 100%
V5BLM1 Trypanosoma cruzi 31% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS