ATP synthase mitochondrial F1 complex assembly factor 1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP11 protein, putative

Species:

Leishmania mexicana

UniProt:

E9B673_LEIMU

TriTrypDb:

LmxM.34.1950

Length:

235

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	12
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043231	intracellular membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12
GO:0005737	cytoplasm	2	1

Expansion

Sequence features

E9B673

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B673

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	12
GO:0016043	cellular component organization	3	12
GO:0022607	cellular component assembly	4	12
GO:0043933	protein-containing complex organization	4	12
GO:0065003	protein-containing complex assembly	5	12
GO:0071840	cellular component organization or biogenesis	2	12
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	8	1
GO:0043461	proton-transporting ATP synthase complex assembly	7	1
GO:0070071	proton-transporting two-sector ATPase complex assembly	6	1

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	16	18	PF00675	0.320
CLV_PCSK_KEX2_1	13	15	PF00082	0.433
CLV_PCSK_KEX2_1	142	144	PF00082	0.412
CLV_PCSK_KEX2_1	172	174	PF00082	0.300
CLV_PCSK_PC1ET2_1	13	15	PF00082	0.433
CLV_PCSK_PC1ET2_1	142	144	PF00082	0.407
CLV_PCSK_PC1ET2_1	172	174	PF00082	0.297
CLV_PCSK_SKI1_1	184	188	PF00082	0.382
CLV_PCSK_SKI1_1	82	86	PF00082	0.297
DEG_APCC_DBOX_1	16	24	PF00400	0.308
DEG_MDM2_SWIB_1	48	56	PF02201	0.313
DEG_Nend_Nbox_1	1	3	PF02207	0.536
DEG_SCF_FBW7_2	96	103	PF00400	0.351
DOC_CKS1_1	213	218	PF01111	0.466
DOC_CKS1_1	31	36	PF01111	0.320
DOC_CYCLIN_RxL_1	124	135	PF00134	0.357
DOC_MAPK_gen_1	125	132	PF00069	0.300
DOC_MAPK_gen_1	142	149	PF00069	0.407
DOC_PP4_FxxP_1	12	15	PF00568	0.656
DOC_PP4_FxxP_1	74	77	PF00568	0.297
DOC_WW_Pin1_4	212	217	PF00397	0.483
DOC_WW_Pin1_4	30	35	PF00397	0.301
DOC_WW_Pin1_4	68	73	PF00397	0.402
DOC_WW_Pin1_4	96	101	PF00397	0.351
LIG_14-3-3_CanoR_1	17	21	PF00244	0.349
LIG_14-3-3_CanoR_1	54	64	PF00244	0.308
LIG_APCC_ABBA_1	76	81	PF00400	0.389
LIG_BIR_III_4	207	211	PF00653	0.514
LIG_BRCT_BRCA1_1	70	74	PF00533	0.389
LIG_deltaCOP1_diTrp_1	164	170	PF00928	0.313
LIG_FHA_1	148	154	PF00498	0.297
LIG_FHA_1	225	231	PF00498	0.577
LIG_FHA_2	213	219	PF00498	0.460
LIG_GBD_Chelix_1	220	228	PF00786	0.545
LIG_LIR_Apic_2	71	77	PF02991	0.335
LIG_LIR_Gen_1	178	186	PF02991	0.483
LIG_LIR_Gen_1	203	213	PF02991	0.374
LIG_LIR_Nem_3	138	144	PF02991	0.435
LIG_LIR_Nem_3	158	162	PF02991	0.317
LIG_LIR_Nem_3	178	182	PF02991	0.297
LIG_LIR_Nem_3	203	209	PF02991	0.385
LIG_LIR_Nem_3	58	64	PF02991	0.319
LIG_LIR_Nem_3	71	76	PF02991	0.269
LIG_MLH1_MIPbox_1	70	74	PF16413	0.389
LIG_Pex14_1	166	170	PF04695	0.313
LIG_Pex14_2	48	52	PF04695	0.297
LIG_SH2_CRK	157	161	PF00017	0.313
LIG_SH2_STAP1	163	167	PF00017	0.313
LIG_SH2_STAT5	11	14	PF00017	0.661
LIG_SH2_STAT5	157	160	PF00017	0.313
LIG_SH2_STAT5	73	76	PF00017	0.297
LIG_TRFH_1	62	66	PF08558	0.389
LIG_WRC_WIRS_1	167	172	PF05994	0.389
MOD_CK2_1	16	22	PF00069	0.313
MOD_CK2_1	24	30	PF00069	0.313
MOD_Cter_Amidation	15	18	PF01082	0.297
MOD_NEK2_1	123	128	PF00069	0.316
MOD_NEK2_1	2	7	PF00069	0.560
MOD_NEK2_1	29	34	PF00069	0.421
MOD_NEK2_2	24	29	PF00069	0.433
MOD_PIKK_1	147	153	PF00454	0.297
MOD_PKA_2	16	22	PF00069	0.237
MOD_PKA_2	2	8	PF00069	0.564
MOD_Plk_4	24	30	PF00069	0.317
MOD_Plk_4	36	42	PF00069	0.264
MOD_ProDKin_1	212	218	PF00069	0.475
MOD_ProDKin_1	30	36	PF00069	0.301
MOD_ProDKin_1	68	74	PF00069	0.402
MOD_ProDKin_1	96	102	PF00069	0.351
MOD_SUMO_for_1	136	139	PF00179	0.433
MOD_SUMO_for_1	186	189	PF00179	0.384
MOD_SUMO_rev_2	193	202	PF00179	0.514
TRG_ENDOCYTIC_2	156	159	PF00928	0.313
TRG_ENDOCYTIC_2	179	182	PF00928	0.415
TRG_ENDOCYTIC_2	206	209	PF00928	0.401
TRG_ENDOCYTIC_2	61	64	PF00928	0.316
TRG_ENDOCYTIC_2	73	76	PF00928	0.316
TRG_Pf-PMV_PEXEL_1	18	22	PF00026	0.297

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P324	Leptomonas seymouri	87%	100%
A0A0S4JHC0	Bodo saltans	70%	99%
A0A1X0P5W7	Trypanosomatidae	70%	100%
A0A3Q8IPF8	Leishmania donovani	97%	100%
A0A3R7RMJ9	Trypanosoma rangeli	68%	98%
A4HML6	Leishmania braziliensis	91%	100%
A4IB93	Leishmania infantum	97%	100%
C9ZZL8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	95%
E9AF17	Leishmania major	97%	100%
V5B8Y3	Trypanosoma cruzi	68%	98%