LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B672_LEIMU
TriTrypDb:
LmxM.34.1945
Length:
618

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B672
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B672

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 235 239 PF00656 0.472
CLV_C14_Caspase3-7 274 278 PF00656 0.350
CLV_C14_Caspase3-7 507 511 PF00656 0.639
CLV_NRD_NRD_1 151 153 PF00675 0.683
CLV_NRD_NRD_1 301 303 PF00675 0.457
CLV_NRD_NRD_1 360 362 PF00675 0.545
CLV_NRD_NRD_1 394 396 PF00675 0.603
CLV_NRD_NRD_1 438 440 PF00675 0.715
CLV_NRD_NRD_1 470 472 PF00675 0.799
CLV_NRD_NRD_1 494 496 PF00675 0.570
CLV_NRD_NRD_1 529 531 PF00675 0.655
CLV_NRD_NRD_1 534 536 PF00675 0.630
CLV_NRD_NRD_1 555 557 PF00675 0.691
CLV_NRD_NRD_1 613 615 PF00675 0.622
CLV_NRD_NRD_1 91 93 PF00675 0.397
CLV_PCSK_KEX2_1 150 152 PF00082 0.683
CLV_PCSK_KEX2_1 301 303 PF00082 0.529
CLV_PCSK_KEX2_1 360 362 PF00082 0.545
CLV_PCSK_KEX2_1 394 396 PF00082 0.603
CLV_PCSK_KEX2_1 438 440 PF00082 0.715
CLV_PCSK_KEX2_1 469 471 PF00082 0.783
CLV_PCSK_KEX2_1 494 496 PF00082 0.610
CLV_PCSK_KEX2_1 534 536 PF00082 0.647
CLV_PCSK_KEX2_1 555 557 PF00082 0.691
CLV_PCSK_KEX2_1 613 615 PF00082 0.622
CLV_PCSK_PC7_1 147 153 PF00082 0.566
CLV_PCSK_PC7_1 530 536 PF00082 0.667
CLV_PCSK_SKI1_1 16 20 PF00082 0.276
CLV_PCSK_SKI1_1 205 209 PF00082 0.352
CLV_PCSK_SKI1_1 217 221 PF00082 0.380
CLV_PCSK_SKI1_1 36 40 PF00082 0.542
CLV_PCSK_SKI1_1 589 593 PF00082 0.707
CLV_PCSK_SKI1_1 614 618 PF00082 0.616
DEG_APCC_DBOX_1 286 294 PF00400 0.518
DEG_SPOP_SBC_1 461 465 PF00917 0.710
DEG_SPOP_SBC_1 61 65 PF00917 0.574
DEG_SPOP_SBC_1 84 88 PF00917 0.476
DOC_CKS1_1 134 139 PF01111 0.530
DOC_CKS1_1 475 480 PF01111 0.613
DOC_CYCLIN_yCln2_LP_2 443 449 PF00134 0.649
DOC_MAPK_gen_1 150 158 PF00069 0.662
DOC_MAPK_gen_1 339 347 PF00069 0.532
DOC_MAPK_MEF2A_6 22 30 PF00069 0.294
DOC_MAPK_MEF2A_6 341 349 PF00069 0.529
DOC_MIT_MIM_1 200 209 PF04212 0.467
DOC_PP4_FxxP_1 220 223 PF00568 0.416
DOC_PP4_FxxP_1 372 375 PF00568 0.667
DOC_PP4_FxxP_1 475 478 PF00568 0.627
DOC_SPAK_OSR1_1 114 118 PF12202 0.269
DOC_USP7_MATH_1 146 150 PF00917 0.608
DOC_USP7_MATH_1 162 166 PF00917 0.670
DOC_USP7_MATH_1 352 356 PF00917 0.530
DOC_USP7_MATH_1 386 390 PF00917 0.616
DOC_USP7_MATH_1 45 49 PF00917 0.639
DOC_USP7_MATH_1 462 466 PF00917 0.788
DOC_USP7_MATH_1 484 488 PF00917 0.640
DOC_USP7_MATH_1 562 566 PF00917 0.585
DOC_USP7_MATH_1 570 574 PF00917 0.634
DOC_USP7_MATH_1 591 595 PF00917 0.707
DOC_USP7_MATH_1 605 609 PF00917 0.552
DOC_USP7_MATH_1 61 65 PF00917 0.608
DOC_USP7_UBL2_3 93 97 PF12436 0.425
DOC_WW_Pin1_4 107 112 PF00397 0.475
DOC_WW_Pin1_4 133 138 PF00397 0.547
DOC_WW_Pin1_4 248 253 PF00397 0.720
DOC_WW_Pin1_4 442 447 PF00397 0.626
DOC_WW_Pin1_4 474 479 PF00397 0.626
DOC_WW_Pin1_4 512 517 PF00397 0.627
DOC_WW_Pin1_4 566 571 PF00397 0.595
DOC_WW_Pin1_4 597 602 PF00397 0.599
LIG_14-3-3_CanoR_1 16 25 PF00244 0.479
LIG_14-3-3_CanoR_1 181 190 PF00244 0.458
LIG_14-3-3_CanoR_1 205 210 PF00244 0.350
LIG_14-3-3_CanoR_1 266 270 PF00244 0.463
LIG_14-3-3_CanoR_1 27 31 PF00244 0.386
LIG_14-3-3_CanoR_1 360 364 PF00244 0.553
LIG_14-3-3_CanoR_1 365 373 PF00244 0.679
LIG_14-3-3_CanoR_1 438 444 PF00244 0.650
LIG_14-3-3_CanoR_1 469 478 PF00244 0.713
LIG_14-3-3_CanoR_1 546 554 PF00244 0.662
LIG_14-3-3_CanoR_1 578 587 PF00244 0.594
LIG_14-3-3_CanoR_1 589 597 PF00244 0.652
LIG_14-3-3_CanoR_1 72 78 PF00244 0.476
LIG_14-3-3_CanoR_1 92 96 PF00244 0.401
LIG_BIR_II_1 1 5 PF00653 0.404
LIG_BRCT_BRCA1_1 471 475 PF00533 0.720
LIG_CaM_IQ_9 315 330 PF13499 0.408
LIG_FHA_1 158 164 PF00498 0.480
LIG_FHA_1 214 220 PF00498 0.399
LIG_FHA_1 548 554 PF00498 0.648
LIG_FHA_2 117 123 PF00498 0.385
LIG_FHA_2 167 173 PF00498 0.645
LIG_FHA_2 187 193 PF00498 0.480
LIG_FHA_2 270 276 PF00498 0.400
LIG_FHA_2 471 477 PF00498 0.643
LIG_FHA_2 76 82 PF00498 0.478
LIG_IBAR_NPY_1 398 400 PF08397 0.585
LIG_Integrin_RGD_1 501 503 PF01839 0.719
LIG_LIR_Apic_2 472 478 PF02991 0.639
LIG_LIR_Gen_1 203 213 PF02991 0.370
LIG_LIR_Gen_1 94 103 PF02991 0.379
LIG_LIR_Nem_3 203 209 PF02991 0.405
LIG_LIR_Nem_3 409 415 PF02991 0.636
LIG_LIR_Nem_3 94 98 PF02991 0.425
LIG_SH2_CRK 103 107 PF00017 0.443
LIG_SH2_PTP2 412 415 PF00017 0.512
LIG_SH2_STAP1 103 107 PF00017 0.443
LIG_SH2_STAP1 211 215 PF00017 0.405
LIG_SH2_STAT3 421 424 PF00017 0.640
LIG_SH2_STAT5 13 16 PF00017 0.378
LIG_SH2_STAT5 400 403 PF00017 0.584
LIG_SH2_STAT5 412 415 PF00017 0.617
LIG_SH3_3 443 449 PF00018 0.697
LIG_SH3_3 526 532 PF00018 0.617
LIG_SUMO_SIM_par_1 188 196 PF11976 0.471
LIG_SUMO_SIM_par_1 81 88 PF11976 0.358
MOD_CDC14_SPxK_1 251 254 PF00782 0.457
MOD_CDK_SPK_2 597 602 PF00069 0.599
MOD_CDK_SPxK_1 133 139 PF00069 0.592
MOD_CDK_SPxK_1 248 254 PF00069 0.457
MOD_CDK_SPxxK_3 107 114 PF00069 0.290
MOD_CK1_1 2 8 PF00069 0.460
MOD_CK1_1 268 274 PF00069 0.502
MOD_CK1_1 288 294 PF00069 0.339
MOD_CK1_1 355 361 PF00069 0.497
MOD_CK1_1 377 383 PF00069 0.587
MOD_CK1_1 405 411 PF00069 0.763
MOD_CK1_1 426 432 PF00069 0.652
MOD_CK1_1 463 469 PF00069 0.678
MOD_CK1_1 50 56 PF00069 0.691
MOD_CK1_1 537 543 PF00069 0.721
MOD_CK1_1 545 551 PF00069 0.627
MOD_CK1_1 573 579 PF00069 0.616
MOD_CK2_1 116 122 PF00069 0.384
MOD_CK2_1 186 192 PF00069 0.491
MOD_CK2_1 269 275 PF00069 0.461
MOD_CK2_1 288 294 PF00069 0.466
MOD_CK2_1 73 79 PF00069 0.396
MOD_GlcNHglycan 232 235 PF01048 0.694
MOD_GlcNHglycan 248 251 PF01048 0.542
MOD_GlcNHglycan 376 379 PF01048 0.568
MOD_GlcNHglycan 384 387 PF01048 0.608
MOD_GlcNHglycan 388 391 PF01048 0.611
MOD_GlcNHglycan 41 45 PF01048 0.619
MOD_GlcNHglycan 425 428 PF01048 0.691
MOD_GlcNHglycan 434 437 PF01048 0.636
MOD_GlcNHglycan 506 509 PF01048 0.601
MOD_GlcNHglycan 537 540 PF01048 0.667
MOD_GlcNHglycan 563 567 PF01048 0.746
MOD_GlcNHglycan 580 583 PF01048 0.486
MOD_GlcNHglycan 607 610 PF01048 0.694
MOD_GlcNHglycan 65 68 PF01048 0.731
MOD_GlcNHglycan 87 90 PF01048 0.457
MOD_GSK3_1 133 140 PF00069 0.583
MOD_GSK3_1 162 169 PF00069 0.718
MOD_GSK3_1 2 9 PF00069 0.298
MOD_GSK3_1 226 233 PF00069 0.615
MOD_GSK3_1 242 249 PF00069 0.487
MOD_GSK3_1 264 271 PF00069 0.508
MOD_GSK3_1 28 35 PF00069 0.545
MOD_GSK3_1 288 295 PF00069 0.388
MOD_GSK3_1 355 362 PF00069 0.540
MOD_GSK3_1 382 389 PF00069 0.800
MOD_GSK3_1 428 435 PF00069 0.646
MOD_GSK3_1 460 467 PF00069 0.804
MOD_GSK3_1 470 477 PF00069 0.608
MOD_GSK3_1 535 542 PF00069 0.647
MOD_GSK3_1 545 552 PF00069 0.676
MOD_GSK3_1 562 569 PF00069 0.800
MOD_GSK3_1 570 577 PF00069 0.607
MOD_GSK3_1 587 594 PF00069 0.628
MOD_GSK3_1 605 612 PF00069 0.619
MOD_N-GLC_1 32 37 PF02516 0.547
MOD_NEK2_1 116 121 PF00069 0.477
MOD_NEK2_1 166 171 PF00069 0.638
MOD_NEK2_1 26 31 PF00069 0.395
MOD_NEK2_1 453 458 PF00069 0.648
MOD_NEK2_1 587 592 PF00069 0.626
MOD_NEK2_1 62 67 PF00069 0.629
MOD_NEK2_1 73 78 PF00069 0.351
MOD_NEK2_1 83 88 PF00069 0.399
MOD_OFUCOSY 4 10 PF10250 0.282
MOD_PIKK_1 288 294 PF00454 0.339
MOD_PIKK_1 352 358 PF00454 0.547
MOD_PIKK_1 365 371 PF00454 0.460
MOD_PKA_1 469 475 PF00069 0.719
MOD_PKA_1 494 500 PF00069 0.602
MOD_PKA_1 534 540 PF00069 0.719
MOD_PKA_2 141 147 PF00069 0.573
MOD_PKA_2 26 32 PF00069 0.350
MOD_PKA_2 265 271 PF00069 0.459
MOD_PKA_2 288 294 PF00069 0.339
MOD_PKA_2 359 365 PF00069 0.515
MOD_PKA_2 405 411 PF00069 0.737
MOD_PKA_2 432 438 PF00069 0.711
MOD_PKA_2 453 459 PF00069 0.662
MOD_PKA_2 469 475 PF00069 0.616
MOD_PKA_2 494 500 PF00069 0.715
MOD_PKA_2 534 540 PF00069 0.650
MOD_PKA_2 545 551 PF00069 0.652
MOD_PKA_2 577 583 PF00069 0.637
MOD_PKA_2 91 97 PF00069 0.399
MOD_Plk_1 2 8 PF00069 0.384
MOD_Plk_1 256 262 PF00069 0.606
MOD_Plk_1 45 51 PF00069 0.448
MOD_Plk_4 186 192 PF00069 0.491
MOD_Plk_4 2 8 PF00069 0.384
MOD_Plk_4 50 56 PF00069 0.595
MOD_Plk_4 556 562 PF00069 0.574
MOD_ProDKin_1 107 113 PF00069 0.467
MOD_ProDKin_1 133 139 PF00069 0.556
MOD_ProDKin_1 248 254 PF00069 0.723
MOD_ProDKin_1 442 448 PF00069 0.625
MOD_ProDKin_1 474 480 PF00069 0.619
MOD_ProDKin_1 512 518 PF00069 0.626
MOD_ProDKin_1 566 572 PF00069 0.597
MOD_ProDKin_1 597 603 PF00069 0.600
TRG_DiLeu_BaEn_1 303 308 PF01217 0.452
TRG_DiLeu_BaLyEn_6 21 26 PF01217 0.308
TRG_ENDOCYTIC_2 103 106 PF00928 0.438
TRG_ENDOCYTIC_2 412 415 PF00928 0.645
TRG_ER_diArg_1 150 152 PF00400 0.637
TRG_ER_diArg_1 284 287 PF00400 0.516
TRG_ER_diArg_1 300 302 PF00400 0.364
TRG_ER_diArg_1 338 341 PF00400 0.479
TRG_ER_diArg_1 469 471 PF00400 0.785
TRG_ER_diArg_1 493 495 PF00400 0.609
TRG_ER_diArg_1 554 556 PF00400 0.666
TRG_NES_CRM1_1 319 334 PF08389 0.516
TRG_Pf-PMV_PEXEL_1 205 210 PF00026 0.350
TRG_Pf-PMV_PEXEL_1 402 407 PF00026 0.597

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PBH3 Leptomonas seymouri 46% 93%
A0A3S7X983 Leishmania donovani 89% 100%
A4HML5 Leishmania braziliensis 75% 100%
A4IB92 Leishmania infantum 89% 100%
E9AF16 Leishmania major 88% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS