Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B661_LEIMU

TriTrypDb:

LmxM.34.1840

Length:

150


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

E9B661

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B661


Leishmania	From	To	Domain/Motif	Score
DEG_Nend_Nbox_1	1	3	PF02207	0.638
DOC_CKS1_1	43	48	PF01111	0.335
DOC_PP2B_LxvP_1	143	146	PF13499	0.527
DOC_USP7_MATH_1	136	140	PF00917	0.737
DOC_WW_Pin1_4	141	146	PF00397	0.587
DOC_WW_Pin1_4	42	47	PF00397	0.335
LIG_FHA_1	114	120	PF00498	0.600
LIG_FHA_1	36	42	PF00498	0.284
LIG_FHA_1	43	49	PF00498	0.420
LIG_FHA_1	83	89	PF00498	0.695
LIG_LIR_Gen_1	135	145	PF02991	0.616
LIG_LIR_Gen_1	38	48	PF02991	0.335
LIG_LIR_Nem_3	135	140	PF02991	0.645
LIG_LIR_Nem_3	34	39	PF02991	0.393
LIG_PDZ_Class_2	145	150	PF00595	0.531
LIG_Pex14_1	36	40	PF04695	0.288
LIG_SH2_CRK	137	141	PF00017	0.583
LIG_SH2_NCK_1	137	141	PF00017	0.655
LIG_SH2_PTP2	40	43	PF00017	0.431
LIG_SH2_STAT5	30	33	PF00017	0.550
LIG_SH2_STAT5	40	43	PF00017	0.431
LIG_SH2_STAT5	57	60	PF00017	0.300
LIG_SH3_3	21	27	PF00018	0.300
LIG_SH3_3	40	46	PF00018	0.361
LIG_TYR_ITSM	36	43	PF00017	0.325
LIG_WRC_WIRS_1	12	17	PF05994	0.225
MOD_CK1_1	138	144	PF00069	0.654
MOD_CK1_1	14	20	PF00069	0.458
MOD_CK1_1	69	75	PF00069	0.698
MOD_CK2_1	69	75	PF00069	0.596
MOD_GlcNHglycan	16	19	PF01048	0.372
MOD_GlcNHglycan	2	5	PF01048	0.386
MOD_GSK3_1	135	142	PF00069	0.569
MOD_GSK3_1	31	38	PF00069	0.461
MOD_GSK3_1	65	72	PF00069	0.634
MOD_GSK3_1	82	89	PF00069	0.646
MOD_N-GLC_1	86	91	PF02516	0.353
MOD_NEK2_1	19	24	PF00069	0.355
MOD_NEK2_1	35	40	PF00069	0.356
MOD_Plk_1	128	134	PF00069	0.585
MOD_Plk_1	86	92	PF00069	0.627
MOD_Plk_4	11	17	PF00069	0.250
MOD_Plk_4	114	120	PF00069	0.657
MOD_Plk_4	31	37	PF00069	0.369
MOD_Plk_4	66	72	PF00069	0.676
MOD_Plk_4	86	92	PF00069	0.648
MOD_ProDKin_1	141	147	PF00069	0.585
MOD_ProDKin_1	42	48	PF00069	0.335
MOD_SUMO_for_1	105	108	PF00179	0.625
TRG_ENDOCYTIC_2	137	140	PF00928	0.631
TRG_ENDOCYTIC_2	40	43	PF00928	0.431
TRG_ENDOCYTIC_2	57	60	PF00928	0.307


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJI6	Leptomonas seymouri	56%	100%
A0A1X0P639	Trypanosomatidae	36%	100%
A0A3Q8IM56	Leishmania donovani	90%	100%
A4HMK5	Leishmania braziliensis	72%	100%
A4IB84	Leishmania infantum	90%	100%
C9ZZK9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9AF05	Leishmania major	90%	100%
V5BHZ7	Trypanosoma cruzi	40%	99%