Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B642_LEIMU

TriTrypDb:

LmxM.34.1640

Length:

357

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B642

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B642

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	229	231	PF00675	0.513
CLV_NRD_NRD_1	254	256	PF00675	0.584
CLV_PCSK_KEX2_1	119	121	PF00082	0.530
CLV_PCSK_KEX2_1	229	231	PF00082	0.513
CLV_PCSK_KEX2_1	254	256	PF00082	0.574
CLV_PCSK_PC1ET2_1	119	121	PF00082	0.530
CLV_PCSK_SKI1_1	245	249	PF00082	0.560
CLV_PCSK_SKI1_1	277	281	PF00082	0.495
CLV_PCSK_SKI1_1	72	76	PF00082	0.528
DEG_Nend_UBRbox_1	1	4	PF02207	0.534
DEG_SPOP_SBC_1	219	223	PF00917	0.451
DOC_CYCLIN_yCln2_LP_2	89	95	PF00134	0.503
DOC_MIT_MIM_1	348	357	PF04212	0.534
DOC_PP4_FxxP_1	145	148	PF00568	0.571
DOC_PP4_FxxP_1	159	162	PF00568	0.417
DOC_USP7_MATH_1	190	194	PF00917	0.651
DOC_USP7_MATH_1	219	223	PF00917	0.588
DOC_USP7_MATH_1	312	316	PF00917	0.577
DOC_USP7_MATH_1	328	332	PF00917	0.586
DOC_WW_Pin1_4	158	163	PF00397	0.687
DOC_WW_Pin1_4	75	80	PF00397	0.636
DOC_WW_Pin1_4	88	93	PF00397	0.553
LIG_14-3-3_CanoR_1	120	129	PF00244	0.527
LIG_14-3-3_CanoR_1	151	159	PF00244	0.693
LIG_Actin_WH2_2	294	310	PF00022	0.595
LIG_Actin_WH2_2	68	84	PF00022	0.439
LIG_APCC_ABBA_1	266	271	PF00400	0.516
LIG_BRCT_BRCA1_1	155	159	PF00533	0.574
LIG_EH1_1	241	249	PF00400	0.562
LIG_FHA_1	247	253	PF00498	0.488
LIG_FHA_1	311	317	PF00498	0.553
LIG_FHA_1	338	344	PF00498	0.378
LIG_FHA_1	55	61	PF00498	0.613
LIG_LIR_Apic_2	143	148	PF02991	0.571
LIG_LIR_Apic_2	156	162	PF02991	0.556
LIG_LIR_Nem_3	264	269	PF02991	0.539
LIG_LIR_Nem_3	281	286	PF02991	0.550
LIG_MAD2	4	12	PF02301	0.614
LIG_NRBOX	213	219	PF00104	0.536
LIG_PDZ_Class_3	352	357	PF00595	0.594
LIG_Pex14_2	266	270	PF04695	0.632
LIG_SH2_SRC	167	170	PF00017	0.425
LIG_SH2_STAT3	284	287	PF00017	0.599
LIG_SH2_STAT5	167	170	PF00017	0.500
LIG_SH3_3	13	19	PF00018	0.634
LIG_SH3_3	3	9	PF00018	0.620
LIG_TRAF2_1	130	133	PF00917	0.730
LIG_WW_1	147	150	PF00397	0.651
MOD_CDK_SPxxK_3	75	82	PF00069	0.594
MOD_CK1_1	154	160	PF00069	0.654
MOD_CK1_1	161	167	PF00069	0.472
MOD_CK1_1	222	228	PF00069	0.514
MOD_CK1_1	28	34	PF00069	0.650
MOD_CK1_1	84	90	PF00069	0.543
MOD_CK2_1	127	133	PF00069	0.670
MOD_CK2_1	190	196	PF00069	0.726
MOD_CK2_1	202	208	PF00069	0.515
MOD_GlcNHglycan	129	132	PF01048	0.671
MOD_GlcNHglycan	153	156	PF01048	0.560
MOD_GlcNHglycan	169	172	PF01048	0.426
MOD_GlcNHglycan	185	188	PF01048	0.621
MOD_GlcNHglycan	192	195	PF01048	0.660
MOD_GlcNHglycan	287	290	PF01048	0.637
MOD_GlcNHglycan	98	101	PF01048	0.673
MOD_GSK3_1	150	157	PF00069	0.743
MOD_GSK3_1	218	225	PF00069	0.486
MOD_GSK3_1	25	32	PF00069	0.641
MOD_GSK3_1	285	292	PF00069	0.573
MOD_GSK3_1	84	91	PF00069	0.529
MOD_N-GLC_1	25	30	PF02516	0.567
MOD_NEK2_1	183	188	PF00069	0.454
MOD_NEK2_1	218	223	PF00069	0.510
MOD_PIKK_1	161	167	PF00454	0.560
MOD_PIKK_1	222	228	PF00454	0.494
MOD_PKA_2	150	156	PF00069	0.655
MOD_PKA_2	81	87	PF00069	0.521
MOD_Plk_1	219	225	PF00069	0.658
MOD_Plk_1	337	343	PF00069	0.392
MOD_Plk_1	84	90	PF00069	0.531
MOD_Plk_4	11	17	PF00069	0.596
MOD_Plk_4	328	334	PF00069	0.585
MOD_Plk_4	337	343	PF00069	0.392
MOD_ProDKin_1	158	164	PF00069	0.683
MOD_ProDKin_1	75	81	PF00069	0.640
MOD_ProDKin_1	88	94	PF00069	0.553
TRG_DiLeu_BaEn_1	178	183	PF01217	0.608
TRG_ENDOCYTIC_2	283	286	PF00928	0.535
TRG_ER_diArg_1	1	4	PF00400	0.609
TRG_ER_diArg_1	242	245	PF00400	0.552

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKF7	Leptomonas seymouri	34%	100%
A0A3S7X929	Leishmania donovani	85%	100%
A4HMI5	Leishmania braziliensis	71%	99%
A4IB65	Leishmania infantum	85%	100%
E9AEY6	Leishmania major	87%	100%