LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B633_LEIMU
TriTrypDb:
LmxM.34.1550
Length:
680

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B633
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B633

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 381 385 PF00656 0.557
CLV_NRD_NRD_1 132 134 PF00675 0.731
CLV_NRD_NRD_1 230 232 PF00675 0.545
CLV_NRD_NRD_1 324 326 PF00675 0.398
CLV_NRD_NRD_1 345 347 PF00675 0.614
CLV_NRD_NRD_1 355 357 PF00675 0.619
CLV_NRD_NRD_1 412 414 PF00675 0.475
CLV_NRD_NRD_1 468 470 PF00675 0.412
CLV_NRD_NRD_1 505 507 PF00675 0.640
CLV_PCSK_KEX2_1 132 134 PF00082 0.731
CLV_PCSK_KEX2_1 324 326 PF00082 0.398
CLV_PCSK_KEX2_1 345 347 PF00082 0.614
CLV_PCSK_KEX2_1 355 357 PF00082 0.615
CLV_PCSK_KEX2_1 411 413 PF00082 0.447
CLV_PCSK_KEX2_1 468 470 PF00082 0.412
CLV_PCSK_KEX2_1 504 506 PF00082 0.671
CLV_PCSK_PC1ET2_1 411 413 PF00082 0.507
CLV_PCSK_PC7_1 464 470 PF00082 0.410
CLV_PCSK_SKI1_1 225 229 PF00082 0.651
CLV_PCSK_SKI1_1 231 235 PF00082 0.590
CLV_PCSK_SKI1_1 468 472 PF00082 0.392
CLV_PCSK_SKI1_1 96 100 PF00082 0.500
DEG_APCC_DBOX_1 467 475 PF00400 0.386
DEG_APCC_DBOX_1 54 62 PF00400 0.402
DEG_Nend_Nbox_1 1 3 PF02207 0.515
DEG_SIAH_1 356 364 PF03145 0.487
DEG_SPOP_SBC_1 595 599 PF00917 0.515
DEG_SPOP_SBC_1 601 605 PF00917 0.605
DOC_CYCLIN_yClb1_LxF_4 305 311 PF00134 0.254
DOC_CYCLIN_yCln2_LP_2 250 256 PF00134 0.395
DOC_CYCLIN_yCln2_LP_2 330 336 PF00134 0.517
DOC_MAPK_gen_1 231 239 PF00069 0.544
DOC_MAPK_gen_1 324 332 PF00069 0.405
DOC_MAPK_gen_1 411 420 PF00069 0.426
DOC_MAPK_RevD_3 309 325 PF00069 0.579
DOC_PP2B_LxvP_1 216 219 PF13499 0.519
DOC_PP2B_LxvP_1 330 333 PF13499 0.431
DOC_PP2B_LxvP_1 373 376 PF13499 0.602
DOC_PP4_MxPP_1 672 675 PF00568 0.487
DOC_USP7_MATH_1 138 142 PF00917 0.638
DOC_USP7_MATH_1 454 458 PF00917 0.442
DOC_USP7_MATH_1 86 90 PF00917 0.594
DOC_WW_Pin1_4 120 125 PF00397 0.629
DOC_WW_Pin1_4 134 139 PF00397 0.620
DOC_WW_Pin1_4 280 285 PF00397 0.647
DOC_WW_Pin1_4 295 300 PF00397 0.347
DOC_WW_Pin1_4 398 403 PF00397 0.551
DOC_WW_Pin1_4 622 627 PF00397 0.681
DOC_WW_Pin1_4 70 75 PF00397 0.706
LIG_14-3-3_CanoR_1 162 167 PF00244 0.536
LIG_14-3-3_CanoR_1 20 26 PF00244 0.407
LIG_14-3-3_CanoR_1 225 231 PF00244 0.664
LIG_14-3-3_CanoR_1 243 250 PF00244 0.429
LIG_14-3-3_CanoR_1 42 50 PF00244 0.478
LIG_14-3-3_CanoR_1 532 536 PF00244 0.310
LIG_14-3-3_CanoR_1 67 74 PF00244 0.724
LIG_AP2alpha_1 9 13 PF02296 0.494
LIG_APCC_ABBAyCdc20_2 411 417 PF00400 0.455
LIG_BRCT_BRCA1_1 223 227 PF00533 0.604
LIG_BRCT_BRCA1_1 306 310 PF00533 0.419
LIG_Clathr_ClatBox_1 403 407 PF01394 0.490
LIG_deltaCOP1_diTrp_1 546 553 PF00928 0.503
LIG_EH1_1 107 115 PF00400 0.446
LIG_FHA_1 195 201 PF00498 0.453
LIG_FHA_1 232 238 PF00498 0.526
LIG_FHA_1 327 333 PF00498 0.424
LIG_FHA_1 385 391 PF00498 0.590
LIG_FHA_1 421 427 PF00498 0.345
LIG_FHA_1 443 449 PF00498 0.429
LIG_FHA_1 477 483 PF00498 0.546
LIG_FHA_1 596 602 PF00498 0.504
LIG_FHA_1 633 639 PF00498 0.639
LIG_FHA_2 156 162 PF00498 0.619
LIG_FHA_2 281 287 PF00498 0.538
LIG_FHA_2 289 295 PF00498 0.444
LIG_FHA_2 484 490 PF00498 0.447
LIG_FHA_2 603 609 PF00498 0.447
LIG_FHA_2 654 660 PF00498 0.465
LIG_LIR_Gen_1 224 233 PF02991 0.716
LIG_LIR_Gen_1 267 277 PF02991 0.614
LIG_LIR_Gen_1 48 58 PF02991 0.470
LIG_LIR_Gen_1 512 519 PF02991 0.476
LIG_LIR_Gen_1 545 554 PF02991 0.426
LIG_LIR_Nem_3 11 16 PF02991 0.496
LIG_LIR_Nem_3 224 230 PF02991 0.737
LIG_LIR_Nem_3 267 273 PF02991 0.565
LIG_LIR_Nem_3 298 303 PF02991 0.469
LIG_LIR_Nem_3 342 347 PF02991 0.623
LIG_LIR_Nem_3 48 53 PF02991 0.426
LIG_LIR_Nem_3 512 517 PF02991 0.487
LIG_PCNA_yPIPBox_3 104 114 PF02747 0.548
LIG_Pex14_2 9 13 PF04695 0.494
LIG_PTAP_UEV_1 258 263 PF05743 0.460
LIG_PTB_Apo_2 561 568 PF02174 0.410
LIG_PTB_Phospho_1 561 567 PF10480 0.413
LIG_RPA_C_Fungi 179 191 PF08784 0.508
LIG_SH2_CRK 344 348 PF00017 0.639
LIG_SH2_STAP1 10 14 PF00017 0.515
LIG_SH2_STAP1 152 156 PF00017 0.551
LIG_SH2_STAT3 425 428 PF00017 0.415
LIG_SH2_STAT5 16 19 PF00017 0.489
LIG_SH2_STAT5 408 411 PF00017 0.568
LIG_SH2_STAT5 425 428 PF00017 0.353
LIG_SH3_1 360 366 PF00018 0.484
LIG_SH3_3 116 122 PF00018 0.439
LIG_SH3_3 256 262 PF00018 0.486
LIG_SH3_3 360 366 PF00018 0.484
LIG_SH3_3 415 421 PF00018 0.453
LIG_SH3_3 623 629 PF00018 0.690
LIG_SH3_5 124 128 PF00018 0.576
LIG_SUMO_SIM_anti_2 109 115 PF11976 0.525
LIG_SUMO_SIM_anti_2 521 527 PF11976 0.414
LIG_SUMO_SIM_anti_2 571 577 PF11976 0.436
LIG_SUMO_SIM_par_1 650 657 PF11976 0.464
LIG_TRAF2_1 264 267 PF00917 0.389
MOD_CDC14_SPxK_1 298 301 PF00782 0.467
MOD_CDK_SPK_2 622 627 PF00069 0.628
MOD_CDK_SPxK_1 295 301 PF00069 0.459
MOD_CDK_SPxxK_3 398 405 PF00069 0.531
MOD_CK1_1 123 129 PF00069 0.744
MOD_CK1_1 155 161 PF00069 0.650
MOD_CK1_1 457 463 PF00069 0.535
MOD_CK1_1 512 518 PF00069 0.518
MOD_CK1_1 536 542 PF00069 0.601
MOD_CK1_1 555 561 PF00069 0.620
MOD_CK1_1 597 603 PF00069 0.443
MOD_CK1_1 621 627 PF00069 0.644
MOD_CK1_1 631 637 PF00069 0.675
MOD_CK1_1 69 75 PF00069 0.636
MOD_CK1_1 84 90 PF00069 0.460
MOD_CK2_1 155 161 PF00069 0.636
MOD_CK2_1 175 181 PF00069 0.408
MOD_CK2_1 288 294 PF00069 0.497
MOD_CK2_1 483 489 PF00069 0.440
MOD_CK2_1 531 537 PF00069 0.362
MOD_CK2_1 602 608 PF00069 0.454
MOD_CK2_1 653 659 PF00069 0.434
MOD_GlcNHglycan 154 157 PF01048 0.628
MOD_GlcNHglycan 177 180 PF01048 0.517
MOD_GlcNHglycan 219 222 PF01048 0.544
MOD_GlcNHglycan 259 262 PF01048 0.464
MOD_GlcNHglycan 357 360 PF01048 0.668
MOD_GlcNHglycan 384 387 PF01048 0.613
MOD_GlcNHglycan 486 489 PF01048 0.653
MOD_GlcNHglycan 500 503 PF01048 0.568
MOD_GlcNHglycan 511 514 PF01048 0.552
MOD_GlcNHglycan 539 542 PF01048 0.611
MOD_GlcNHglycan 557 560 PF01048 0.359
MOD_GSK3_1 134 141 PF00069 0.594
MOD_GSK3_1 14 21 PF00069 0.533
MOD_GSK3_1 151 158 PF00069 0.556
MOD_GSK3_1 217 224 PF00069 0.578
MOD_GSK3_1 378 385 PF00069 0.608
MOD_GSK3_1 456 463 PF00069 0.332
MOD_GSK3_1 476 483 PF00069 0.504
MOD_GSK3_1 533 540 PF00069 0.618
MOD_GSK3_1 595 602 PF00069 0.621
MOD_GSK3_1 61 68 PF00069 0.604
MOD_GSK3_1 618 625 PF00069 0.622
MOD_GSK3_1 628 635 PF00069 0.614
MOD_GSK3_1 653 660 PF00069 0.457
MOD_GSK3_1 69 76 PF00069 0.606
MOD_GSK3_1 80 87 PF00069 0.497
MOD_N-GLC_1 144 149 PF02516 0.631
MOD_N-GLC_1 595 600 PF02516 0.548
MOD_N-GLC_1 621 626 PF02516 0.550
MOD_N-GLC_1 640 645 PF02516 0.609
MOD_NEK2_1 1 6 PF00069 0.531
MOD_NEK2_1 14 19 PF00069 0.655
MOD_NEK2_1 144 149 PF00069 0.663
MOD_NEK2_1 194 199 PF00069 0.456
MOD_NEK2_1 347 352 PF00069 0.664
MOD_NEK2_1 475 480 PF00069 0.423
MOD_NEK2_1 594 599 PF00069 0.560
MOD_NEK2_1 61 66 PF00069 0.644
MOD_NEK2_2 66 71 PF00069 0.606
MOD_PIKK_1 14 20 PF00454 0.666
MOD_PIKK_1 169 175 PF00454 0.609
MOD_PIKK_1 194 200 PF00454 0.507
MOD_PK_1 162 168 PF00069 0.590
MOD_PKA_1 231 237 PF00069 0.554
MOD_PKA_1 355 361 PF00069 0.691
MOD_PKA_2 19 25 PF00069 0.461
MOD_PKA_2 288 294 PF00069 0.603
MOD_PKA_2 347 353 PF00069 0.663
MOD_PKA_2 355 361 PF00069 0.682
MOD_PKA_2 41 47 PF00069 0.469
MOD_PKA_2 531 537 PF00069 0.319
MOD_PKA_2 66 72 PF00069 0.723
MOD_Plk_1 84 90 PF00069 0.404
MOD_Plk_2-3 531 537 PF00069 0.319
MOD_Plk_4 1 7 PF00069 0.529
MOD_Plk_4 106 112 PF00069 0.482
MOD_Plk_4 304 310 PF00069 0.480
MOD_Plk_4 326 332 PF00069 0.451
MOD_Plk_4 335 341 PF00069 0.521
MOD_Plk_4 569 575 PF00069 0.434
MOD_Plk_4 608 614 PF00069 0.533
MOD_ProDKin_1 120 126 PF00069 0.633
MOD_ProDKin_1 134 140 PF00069 0.618
MOD_ProDKin_1 280 286 PF00069 0.639
MOD_ProDKin_1 295 301 PF00069 0.347
MOD_ProDKin_1 398 404 PF00069 0.551
MOD_ProDKin_1 622 628 PF00069 0.684
MOD_ProDKin_1 70 76 PF00069 0.705
TRG_DiLeu_BaEn_1 608 613 PF01217 0.422
TRG_DiLeu_BaLyEn_6 399 404 PF01217 0.524
TRG_ENDOCYTIC_2 10 13 PF00928 0.474
TRG_ENDOCYTIC_2 300 303 PF00928 0.471
TRG_ENDOCYTIC_2 344 347 PF00928 0.630
TRG_ENDOCYTIC_2 50 53 PF00928 0.454
TRG_ER_diArg_1 184 187 PF00400 0.496
TRG_ER_diArg_1 323 325 PF00400 0.385
TRG_ER_diArg_1 344 346 PF00400 0.635
TRG_ER_diArg_1 355 357 PF00400 0.686
TRG_ER_diArg_1 412 414 PF00400 0.480
TRG_ER_diArg_1 468 470 PF00400 0.412
TRG_ER_diArg_1 504 506 PF00400 0.671
TRG_Pf-PMV_PEXEL_1 36 40 PF00026 0.486
TRG_Pf-PMV_PEXEL_1 469 473 PF00026 0.454

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HXS6 Leptomonas seymouri 47% 91%
A0A3Q8IF12 Leishmania donovani 91% 100%
A4HMH6 Leishmania braziliensis 80% 100%
A4IB56 Leishmania infantum 91% 100%
C9ZZG3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
E9AEX7 Leishmania major 88% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS