Rhodanese domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

rhodanese-like domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9B5Z6_LEIMU

TriTrypDb:

LmxM.34.1170

Length:

604

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5Z6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5Z6

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0004792	thiosulfate sulfurtransferase activity	5	1
GO:0016740	transferase activity	2	1
GO:0016782	transferase activity, transferring sulphur-containing groups	3	1
GO:0016783	sulfurtransferase activity	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	116	120	PF00656	0.568
CLV_C14_Caspase3-7	139	143	PF00656	0.561
CLV_C14_Caspase3-7	193	197	PF00656	0.668
CLV_C14_Caspase3-7	575	579	PF00656	0.560
CLV_NRD_NRD_1	135	137	PF00675	0.489
CLV_NRD_NRD_1	235	237	PF00675	0.429
CLV_NRD_NRD_1	430	432	PF00675	0.537
CLV_NRD_NRD_1	444	446	PF00675	0.543
CLV_NRD_NRD_1	537	539	PF00675	0.738
CLV_NRD_NRD_1	602	604	PF00675	0.735
CLV_NRD_NRD_1	76	78	PF00675	0.740
CLV_PCSK_FUR_1	535	539	PF00082	0.632
CLV_PCSK_KEX2_1	135	137	PF00082	0.489
CLV_PCSK_KEX2_1	235	237	PF00082	0.427
CLV_PCSK_KEX2_1	430	432	PF00082	0.537
CLV_PCSK_KEX2_1	444	446	PF00082	0.527
CLV_PCSK_KEX2_1	537	539	PF00082	0.680
CLV_PCSK_KEX2_1	602	604	PF00082	0.735
CLV_PCSK_KEX2_1	76	78	PF00082	0.740
CLV_PCSK_SKI1_1	255	259	PF00082	0.523
CLV_PCSK_SKI1_1	318	322	PF00082	0.440
CLV_PCSK_SKI1_1	445	449	PF00082	0.579
CLV_PCSK_SKI1_1	562	566	PF00082	0.618
DEG_Nend_Nbox_1	1	3	PF02207	0.720
DEG_SPOP_SBC_1	145	149	PF00917	0.688
DEG_SPOP_SBC_1	168	172	PF00917	0.674
DEG_SPOP_SBC_1	295	299	PF00917	0.651
DOC_MAPK_gen_1	379	387	PF00069	0.490
DOC_MAPK_MEF2A_6	558	567	PF00069	0.630
DOC_PP4_FxxP_1	377	380	PF00568	0.480
DOC_USP7_MATH_1	12	16	PF00917	0.688
DOC_USP7_MATH_1	145	149	PF00917	0.698
DOC_USP7_MATH_1	168	172	PF00917	0.759
DOC_USP7_MATH_1	179	183	PF00917	0.599
DOC_USP7_MATH_1	287	291	PF00917	0.637
DOC_USP7_MATH_1	522	526	PF00917	0.716
DOC_USP7_MATH_1	528	532	PF00917	0.755
DOC_USP7_MATH_1	7	11	PF00917	0.706
DOC_USP7_MATH_1	84	88	PF00917	0.801
DOC_USP7_UBL2_3	243	247	PF12436	0.476
DOC_USP7_UBL2_3	37	41	PF12436	0.696
DOC_USP7_UBL2_3	497	501	PF12436	0.587
DOC_WW_Pin1_4	170	175	PF00397	0.731
DOC_WW_Pin1_4	24	29	PF00397	0.682
DOC_WW_Pin1_4	478	483	PF00397	0.573
DOC_WW_Pin1_4	586	591	PF00397	0.687
DOC_WW_Pin1_4	592	597	PF00397	0.726
LIG_14-3-3_CanoR_1	444	450	PF00244	0.584
LIG_14-3-3_CanoR_1	562	568	PF00244	0.647
LIG_14-3-3_CanoR_1	91	97	PF00244	0.713
LIG_Actin_WH2_2	266	284	PF00022	0.528
LIG_BRCT_BRCA1_1	147	151	PF00533	0.707
LIG_eIF4E_1	392	398	PF01652	0.477
LIG_FHA_1	256	262	PF00498	0.591
LIG_FHA_1	38	44	PF00498	0.705
LIG_FHA_1	501	507	PF00498	0.479
LIG_FHA_1	534	540	PF00498	0.642
LIG_FHA_1	543	549	PF00498	0.592
LIG_FHA_1	592	598	PF00498	0.718
LIG_FHA_1	70	76	PF00498	0.619
LIG_FHA_2	182	188	PF00498	0.738
LIG_FHA_2	191	197	PF00498	0.637
LIG_FHA_2	207	213	PF00498	0.614
LIG_FHA_2	239	245	PF00498	0.541
LIG_FHA_2	258	264	PF00498	0.342
LIG_FHA_2	295	301	PF00498	0.579
LIG_FHA_2	322	328	PF00498	0.478
LIG_FHA_2	337	343	PF00498	0.428
LIG_FHA_2	550	556	PF00498	0.700
LIG_FHA_2	573	579	PF00498	0.617
LIG_LIR_Apic_2	204	208	PF02991	0.640
LIG_LIR_Apic_2	374	380	PF02991	0.479
LIG_LIR_Gen_1	329	340	PF02991	0.320
LIG_LIR_Gen_1	359	368	PF02991	0.477
LIG_LIR_Gen_1	462	471	PF02991	0.523
LIG_LIR_Nem_3	329	335	PF02991	0.320
LIG_LIR_Nem_3	344	349	PF02991	0.477
LIG_LIR_Nem_3	359	364	PF02991	0.477
LIG_LIR_Nem_3	404	408	PF02991	0.483
LIG_LIR_Nem_3	462	466	PF02991	0.516
LIG_LIR_Nem_3	494	499	PF02991	0.542
LIG_PCNA_yPIPBox_3	423	433	PF02747	0.492
LIG_Pex14_1	421	425	PF04695	0.548
LIG_SH2_CRK	425	429	PF00017	0.476
LIG_SH2_CRK	496	500	PF00017	0.538
LIG_SH2_SRC	328	331	PF00017	0.423
LIG_SH2_STAT5	389	392	PF00017	0.477
LIG_SH2_STAT5	408	411	PF00017	0.525
LIG_SH2_STAT5	474	477	PF00017	0.641
LIG_SH3_1	41	47	PF00018	0.498
LIG_SH3_3	200	206	PF00018	0.647
LIG_SH3_3	262	268	PF00018	0.528
LIG_SH3_3	41	47	PF00018	0.603
LIG_TRAF2_1	129	132	PF00917	0.613
LIG_TRAF2_1	314	317	PF00917	0.550
LIG_TRAF2_1	367	370	PF00917	0.556
LIG_TRAF2_1	467	470	PF00917	0.527
LIG_UBA3_1	402	410	PF00899	0.520
LIG_WRC_WIRS_1	446	451	PF05994	0.581
LIG_WW_3	599	603	PF00397	0.759
MOD_CDC14_SPxK_1	481	484	PF00782	0.619
MOD_CDK_SPK_2	24	29	PF00069	0.682
MOD_CDK_SPxK_1	478	484	PF00069	0.623
MOD_CDK_SPxxK_3	170	177	PF00069	0.671
MOD_CDK_SPxxK_3	586	593	PF00069	0.707
MOD_CK1_1	147	153	PF00069	0.787
MOD_CK1_1	531	537	PF00069	0.644
MOD_CK1_1	595	601	PF00069	0.805
MOD_CK1_1	93	99	PF00069	0.701
MOD_CK2_1	147	153	PF00069	0.491
MOD_CK2_1	238	244	PF00069	0.540
MOD_CK2_1	257	263	PF00069	0.344
MOD_CK2_1	294	300	PF00069	0.681
MOD_CK2_1	311	317	PF00069	0.321
MOD_CK2_1	321	327	PF00069	0.438
MOD_CK2_1	336	342	PF00069	0.477
MOD_CK2_1	436	442	PF00069	0.580
MOD_CK2_1	98	104	PF00069	0.691
MOD_Cter_Amidation	35	38	PF01082	0.619
MOD_GlcNHglycan	10	13	PF01048	0.720
MOD_GlcNHglycan	158	161	PF01048	0.675
MOD_GlcNHglycan	164	167	PF01048	0.682
MOD_GlcNHglycan	196	199	PF01048	0.720
MOD_GlcNHglycan	291	294	PF01048	0.720
MOD_GlcNHglycan	3	6	PF01048	0.645
MOD_GlcNHglycan	305	308	PF01048	0.436
MOD_GlcNHglycan	313	316	PF01048	0.570
MOD_GlcNHglycan	438	441	PF01048	0.532
MOD_GlcNHglycan	47	50	PF01048	0.781
MOD_GlcNHglycan	82	85	PF01048	0.775
MOD_GlcNHglycan	86	89	PF01048	0.644
MOD_GlcNHglycan	97	100	PF01048	0.559
MOD_GSK3_1	1	8	PF00069	0.727
MOD_GSK3_1	190	197	PF00069	0.636
MOD_GSK3_1	20	27	PF00069	0.494
MOD_GSK3_1	224	231	PF00069	0.472
MOD_GSK3_1	251	258	PF00069	0.568
MOD_GSK3_1	572	579	PF00069	0.537
MOD_GSK3_1	591	598	PF00069	0.812
MOD_GSK3_1	80	87	PF00069	0.808
MOD_GSK3_1	89	96	PF00069	0.709
MOD_N-GLC_1	113	118	PF02516	0.608
MOD_N-GLC_1	190	195	PF02516	0.744
MOD_NEK2_1	1	6	PF00069	0.729
MOD_NEK2_1	144	149	PF00069	0.686
MOD_NEK2_1	169	174	PF00069	0.670
MOD_NEK2_1	224	229	PF00069	0.462
MOD_NEK2_1	257	262	PF00069	0.366
MOD_NEK2_1	294	299	PF00069	0.662
MOD_NEK2_1	320	325	PF00069	0.438
MOD_NEK2_1	475	480	PF00069	0.576
MOD_NEK2_1	78	83	PF00069	0.741
MOD_PIKK_1	528	534	PF00454	0.675
MOD_PIKK_1	595	601	PF00454	0.528
MOD_PKA_1	255	261	PF00069	0.422
MOD_PKA_1	37	43	PF00069	0.611
MOD_PKA_2	475	481	PF00069	0.636
MOD_PKA_2	78	84	PF00069	0.670
MOD_PKA_2	90	96	PF00069	0.658
MOD_PKB_1	77	85	PF00069	0.655
MOD_Plk_1	113	119	PF00069	0.576
MOD_Plk_1	190	196	PF00069	0.746
MOD_Plk_1	213	219	PF00069	0.486
MOD_Plk_1	341	347	PF00069	0.477
MOD_Plk_1	93	99	PF00069	0.546
MOD_Plk_2-3	336	342	PF00069	0.477
MOD_Plk_4	190	196	PF00069	0.527
MOD_Plk_4	224	230	PF00069	0.472
MOD_Plk_4	401	407	PF00069	0.477
MOD_Plk_4	572	578	PF00069	0.576
MOD_ProDKin_1	170	176	PF00069	0.728
MOD_ProDKin_1	24	30	PF00069	0.683
MOD_ProDKin_1	478	484	PF00069	0.574
MOD_ProDKin_1	586	592	PF00069	0.689
MOD_SUMO_for_1	556	559	PF00179	0.565
MOD_SUMO_rev_2	311	320	PF00179	0.499
MOD_SUMO_rev_2	585	595	PF00179	0.732
TRG_DiLeu_BaEn_1	316	321	PF01217	0.498
TRG_DiLeu_BaEn_4	132	138	PF01217	0.576
TRG_DiLeu_BaEn_4	316	322	PF01217	0.549
TRG_ENDOCYTIC_2	408	411	PF00928	0.484
TRG_ENDOCYTIC_2	425	428	PF00928	0.537
TRG_ENDOCYTIC_2	496	499	PF00928	0.541
TRG_ER_diArg_1	134	136	PF00400	0.481
TRG_ER_diArg_1	229	232	PF00400	0.408
TRG_ER_diArg_1	234	236	PF00400	0.420
TRG_ER_diArg_1	429	431	PF00400	0.523
TRG_ER_diArg_1	443	445	PF00400	0.534
TRG_ER_diArg_1	535	538	PF00400	0.691
TRG_ER_diArg_1	601	603	PF00400	0.719
TRG_ER_diArg_1	75	77	PF00400	0.770
TRG_NES_CRM1_1	458	470	PF08389	0.516
TRG_Pf-PMV_PEXEL_1	135	139	PF00026	0.492
TRG_Pf-PMV_PEXEL_1	215	219	PF00026	0.471
TRG_Pf-PMV_PEXEL_1	232	237	PF00026	0.416
TRG_Pf-PMV_PEXEL_1	537	541	PF00026	0.614
TRG_Pf-PMV_PEXEL_1	546	550	PF00026	0.589

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5U9	Leptomonas seymouri	64%	100%
A0A0S4IZW5	Bodo saltans	46%	100%
A0A3Q8IEZ4	Leishmania donovani	89%	99%
A4HMD8	Leishmania braziliensis	77%	99%
A4IB11	Leishmania infantum	89%	99%
E9AEU0	Leishmania major	89%	100%