G-patch domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B5Y6_LEIMU

TriTrypDb:

LmxM.34.1060

Length:

586

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5Y6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5Y6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	243	247	PF00656	0.631
CLV_C14_Caspase3-7	288	292	PF00656	0.711
CLV_C14_Caspase3-7	6	10	PF00656	0.557
CLV_C14_Caspase3-7	96	100	PF00656	0.727
CLV_NRD_NRD_1	116	118	PF00675	0.701
CLV_NRD_NRD_1	122	124	PF00675	0.649
CLV_NRD_NRD_1	136	138	PF00675	0.576
CLV_NRD_NRD_1	139	141	PF00675	0.584
CLV_NRD_NRD_1	16	18	PF00675	0.732
CLV_NRD_NRD_1	161	163	PF00675	0.709
CLV_NRD_NRD_1	165	167	PF00675	0.679
CLV_NRD_NRD_1	21	23	PF00675	0.685
CLV_NRD_NRD_1	219	221	PF00675	0.696
CLV_NRD_NRD_1	244	246	PF00675	0.647
CLV_NRD_NRD_1	277	279	PF00675	0.718
CLV_NRD_NRD_1	306	308	PF00675	0.838
CLV_NRD_NRD_1	391	393	PF00675	0.545
CLV_NRD_NRD_1	41	43	PF00675	0.535
CLV_NRD_NRD_1	580	582	PF00675	0.525
CLV_NRD_NRD_1	67	69	PF00675	0.722
CLV_NRD_NRD_1	73	75	PF00675	0.684
CLV_NRD_NRD_1	91	93	PF00675	0.540
CLV_PCSK_FUR_1	114	118	PF00082	0.659
CLV_PCSK_FUR_1	137	141	PF00082	0.675
CLV_PCSK_FUR_1	142	146	PF00082	0.642
CLV_PCSK_FUR_1	303	307	PF00082	0.694
CLV_PCSK_FUR_1	38	42	PF00082	0.605
CLV_PCSK_FUR_1	389	393	PF00082	0.536
CLV_PCSK_KEX2_1	114	116	PF00082	0.687
CLV_PCSK_KEX2_1	122	124	PF00082	0.629
CLV_PCSK_KEX2_1	136	138	PF00082	0.693
CLV_PCSK_KEX2_1	139	141	PF00082	0.678
CLV_PCSK_KEX2_1	144	146	PF00082	0.769
CLV_PCSK_KEX2_1	16	18	PF00082	0.628
CLV_PCSK_KEX2_1	165	167	PF00082	0.682
CLV_PCSK_KEX2_1	21	23	PF00082	0.578
CLV_PCSK_KEX2_1	219	221	PF00082	0.696
CLV_PCSK_KEX2_1	236	238	PF00082	0.496
CLV_PCSK_KEX2_1	244	246	PF00082	0.605
CLV_PCSK_KEX2_1	277	279	PF00082	0.718
CLV_PCSK_KEX2_1	3	5	PF00082	0.692
CLV_PCSK_KEX2_1	303	305	PF00082	0.828
CLV_PCSK_KEX2_1	306	308	PF00082	0.814
CLV_PCSK_KEX2_1	391	393	PF00082	0.545
CLV_PCSK_KEX2_1	40	42	PF00082	0.539
CLV_PCSK_KEX2_1	580	582	PF00082	0.525
CLV_PCSK_KEX2_1	67	69	PF00082	0.722
CLV_PCSK_KEX2_1	73	75	PF00082	0.684
CLV_PCSK_KEX2_1	91	93	PF00082	0.540
CLV_PCSK_PC1ET2_1	144	146	PF00082	0.843
CLV_PCSK_PC1ET2_1	236	238	PF00082	0.663
CLV_PCSK_PC1ET2_1	3	5	PF00082	0.681
CLV_PCSK_PC7_1	111	117	PF00082	0.656
CLV_PCSK_PC7_1	140	146	PF00082	0.716
CLV_PCSK_PC7_1	17	23	PF00082	0.683
CLV_PCSK_SKI1_1	236	240	PF00082	0.667
CLV_PCSK_SKI1_1	358	362	PF00082	0.489
CLV_PCSK_SKI1_1	395	399	PF00082	0.619
CLV_PCSK_SKI1_1	475	479	PF00082	0.695
DEG_APCC_DBOX_1	357	365	PF00400	0.493
DEG_SPOP_SBC_1	432	436	PF00917	0.647
DOC_CKS1_1	535	540	PF01111	0.690
DOC_CYCLIN_RxL_1	234	243	PF00134	0.667
DOC_PP1_RVXF_1	235	242	PF00149	0.670
DOC_PP4_MxPP_1	269	272	PF00568	0.678
DOC_USP7_MATH_1	183	187	PF00917	0.670
DOC_USP7_MATH_1	199	203	PF00917	0.613
DOC_USP7_MATH_1	340	344	PF00917	0.461
DOC_USP7_MATH_1	400	404	PF00917	0.609
DOC_USP7_MATH_1	432	436	PF00917	0.757
DOC_USP7_MATH_1	481	485	PF00917	0.668
DOC_USP7_MATH_1	486	490	PF00917	0.618
DOC_USP7_MATH_1	565	569	PF00917	0.496
DOC_WW_Pin1_4	202	207	PF00397	0.592
DOC_WW_Pin1_4	524	529	PF00397	0.697
DOC_WW_Pin1_4	534	539	PF00397	0.612
LIG_14-3-3_CanoR_1	125	133	PF00244	0.726
LIG_14-3-3_CanoR_1	307	313	PF00244	0.733
LIG_14-3-3_CanoR_1	413	419	PF00244	0.552
LIG_14-3-3_CanoR_1	85	93	PF00244	0.727
LIG_14-3-3_CterR_2	581	586	PF00244	0.518
LIG_BIR_II_1	1	5	PF00653	0.552
LIG_BIR_III_4	246	250	PF00653	0.678
LIG_EVH1_1	529	533	PF00568	0.663
LIG_FHA_1	376	382	PF00498	0.333
LIG_FHA_1	472	478	PF00498	0.543
LIG_FHA_1	535	541	PF00498	0.553
LIG_FHA_1	561	567	PF00498	0.415
LIG_FHA_2	316	322	PF00498	0.608
LIG_Integrin_isoDGR_2	578	580	PF01839	0.563
LIG_LIR_Apic_2	333	339	PF02991	0.661
LIG_LIR_Nem_3	101	107	PF02991	0.713
LIG_MAD2	85	93	PF02301	0.690
LIG_NRBOX	417	423	PF00104	0.535
LIG_PCNA_yPIPBox_3	413	422	PF02747	0.537
LIG_PTB_Apo_2	570	577	PF02174	0.522
LIG_PTB_Phospho_1	570	576	PF10480	0.526
LIG_RPA_C_Fungi	240	252	PF08784	0.531
LIG_SH2_GRB2like	576	579	PF00017	0.551
LIG_SH2_NCK_1	336	340	PF00017	0.647
LIG_SH2_SRC	576	579	PF00017	0.551
LIG_SH2_STAT5	541	544	PF00017	0.665
LIG_SH2_STAT5	576	579	PF00017	0.551
LIG_SH3_3	200	206	PF00018	0.582
LIG_SH3_3	264	270	PF00018	0.654
LIG_SH3_3	387	393	PF00018	0.534
LIG_SH3_3	527	533	PF00018	0.805
LIG_SH3_3	545	551	PF00018	0.473
LIG_SUMO_SIM_par_1	553	558	PF11976	0.507
LIG_TRAF2_1	93	96	PF00917	0.553
LIG_WRC_WIRS_1	104	109	PF05994	0.595
MOD_CDK_SPxxK_3	202	209	PF00069	0.534
MOD_CK1_1	20	26	PF00069	0.728
MOD_CK1_1	202	208	PF00069	0.671
MOD_CK1_1	328	334	PF00069	0.685
MOD_CK1_1	375	381	PF00069	0.474
MOD_CK1_1	424	430	PF00069	0.613
MOD_CK1_1	462	468	PF00069	0.567
MOD_CK2_1	118	124	PF00069	0.699
MOD_CK2_1	315	321	PF00069	0.613
MOD_CK2_1	97	103	PF00069	0.701
MOD_Cter_Amidation	137	140	PF01082	0.716
MOD_Cter_Amidation	142	145	PF01082	0.668
MOD_Cter_Amidation	160	163	PF01082	0.517
MOD_Cter_Amidation	578	581	PF01082	0.562
MOD_GlcNHglycan	246	250	PF01048	0.678
MOD_GlcNHglycan	294	297	PF01048	0.701
MOD_GlcNHglycan	435	438	PF01048	0.628
MOD_GlcNHglycan	498	501	PF01048	0.587
MOD_GlcNHglycan	6	9	PF01048	0.731
MOD_GlcNHglycan	69	72	PF01048	0.728
MOD_GSK3_1	204	211	PF00069	0.685
MOD_GSK3_1	324	331	PF00069	0.744
MOD_GSK3_1	364	371	PF00069	0.525
MOD_GSK3_1	420	427	PF00069	0.673
MOD_GSK3_1	442	449	PF00069	0.803
MOD_GSK3_1	459	466	PF00069	0.520
MOD_GSK3_1	481	488	PF00069	0.666
MOD_LATS_1	57	63	PF00433	0.698
MOD_LATS_1	65	71	PF00433	0.633
MOD_N-GLC_1	279	284	PF02516	0.681
MOD_N-GLC_1	292	297	PF02516	0.591
MOD_N-GLC_1	325	330	PF02516	0.776
MOD_N-GLC_1	4	9	PF02516	0.665
MOD_N-GLC_1	446	451	PF02516	0.647
MOD_NEK2_1	366	371	PF00069	0.535
MOD_NEK2_1	421	426	PF00069	0.542
MOD_PIKK_1	375	381	PF00454	0.334
MOD_PIKK_1	505	511	PF00454	0.546
MOD_PKA_1	67	73	PF00069	0.673
MOD_PKA_2	110	116	PF00069	0.720
MOD_PKA_2	20	26	PF00069	0.723
MOD_PKA_2	43	49	PF00069	0.732
MOD_PKA_2	60	66	PF00069	0.566
MOD_PKA_2	67	73	PF00069	0.666
MOD_PKB_1	123	131	PF00069	0.667
MOD_PKB_1	305	313	PF00069	0.621
MOD_Plk_1	199	205	PF00069	0.588
MOD_Plk_1	279	285	PF00069	0.680
MOD_Plk_1	324	330	PF00069	0.751
MOD_Plk_1	364	370	PF00069	0.521
MOD_Plk_1	446	452	PF00069	0.632
MOD_Plk_1	453	459	PF00069	0.663
MOD_Plk_1	463	469	PF00069	0.567
MOD_Plk_2-3	103	109	PF00069	0.633
MOD_Plk_2-3	45	51	PF00069	0.731
MOD_Plk_4	331	337	PF00069	0.673
MOD_Plk_4	453	459	PF00069	0.642
MOD_Plk_4	463	469	PF00069	0.558
MOD_Plk_4	486	492	PF00069	0.521
MOD_ProDKin_1	202	208	PF00069	0.596
MOD_ProDKin_1	524	530	PF00069	0.696
MOD_ProDKin_1	534	540	PF00069	0.609
TRG_ENDOCYTIC_2	104	107	PF00928	0.713
TRG_ER_diArg_1	114	117	PF00400	0.728
TRG_ER_diArg_1	136	139	PF00400	0.678
TRG_ER_diArg_1	164	166	PF00400	0.609
TRG_ER_diArg_1	219	222	PF00400	0.699
TRG_ER_diArg_1	281	284	PF00400	0.676
TRG_ER_diArg_1	303	306	PF00400	0.713
TRG_ER_diArg_1	38	41	PF00400	0.603
TRG_ER_diArg_1	388	391	PF00400	0.537
TRG_ER_diArg_1	580	582	PF00400	0.525
TRG_ER_diArg_1	91	94	PF00400	0.722
TRG_NLS_Bipartite_1	144	166	PF00514	0.538
TRG_NLS_MonoExtC_3	161	166	PF00514	0.678
TRG_Pf-PMV_PEXEL_1	190	195	PF00026	0.522

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X8W4	Leishmania donovani	82%	100%
A4HFF4	Leishmania braziliensis	65%	98%
A4IB03	Leishmania infantum	83%	100%
E9AET1	Leishmania major	82%	100%