PSP1 C-terminal domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cell cycle sequence binding phosphoprotein (RBP33), putative

Species:

Leishmania mexicana

UniProt:

E9B5X5_LEIMU

TriTrypDb:

LmxM.34.0950

Length:

414

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9B5X5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5X5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	149	153	PF00656	0.692
CLV_C14_Caspase3-7	159	163	PF00656	0.636
CLV_C14_Caspase3-7	180	184	PF00656	0.658
CLV_C14_Caspase3-7	380	384	PF00656	0.654
CLV_NRD_NRD_1	227	229	PF00675	0.382
CLV_NRD_NRD_1	260	262	PF00675	0.422
CLV_PCSK_KEX2_1	223	225	PF00082	0.423
CLV_PCSK_PC1ET2_1	223	225	PF00082	0.423
CLV_PCSK_SKI1_1	42	46	PF00082	0.602
DEG_COP1_1	119	129	PF00400	0.666
DOC_CYCLIN_RxL_1	314	326	PF00134	0.395
DOC_MAPK_gen_1	314	323	PF00069	0.328
DOC_MAPK_MEF2A_6	317	325	PF00069	0.324
DOC_PP1_RVXF_1	337	344	PF00149	0.315
DOC_USP7_MATH_1	146	150	PF00917	0.727
DOC_USP7_MATH_1	164	168	PF00917	0.515
DOC_USP7_MATH_1	211	215	PF00917	0.522
DOC_USP7_MATH_1	25	29	PF00917	0.660
DOC_USP7_MATH_1	268	272	PF00917	0.444
DOC_USP7_MATH_1	31	35	PF00917	0.601
DOC_USP7_MATH_1	382	386	PF00917	0.583
DOC_USP7_MATH_1	74	78	PF00917	0.761
DOC_USP7_MATH_1	99	103	PF00917	0.563
DOC_WW_Pin1_4	103	108	PF00397	0.615
DOC_WW_Pin1_4	125	130	PF00397	0.543
DOC_WW_Pin1_4	147	152	PF00397	0.657
DOC_WW_Pin1_4	19	24	PF00397	0.590
LIG_14-3-3_CanoR_1	291	298	PF00244	0.315
LIG_14-3-3_CanoR_1	42	47	PF00244	0.528
LIG_14-3-3_CanoR_1	94	98	PF00244	0.669
LIG_APCC_ABBA_1	12	17	PF00400	0.648
LIG_BIR_II_1	1	5	PF00653	0.647
LIG_BIR_III_4	383	387	PF00653	0.677
LIG_BRCT_BRCA1_1	341	345	PF00533	0.315
LIG_BRCT_BRCA1_1	349	353	PF00533	0.315
LIG_FHA_1	265	271	PF00498	0.458
LIG_FHA_2	77	83	PF00498	0.473
LIG_Integrin_isoDGR_2	286	288	PF01839	0.526
LIG_LIR_Nem_3	350	356	PF02991	0.315
LIG_LIR_Nem_3	359	364	PF02991	0.315
LIG_MLH1_MIPbox_1	341	345	PF16413	0.315
LIG_SH2_NCK_1	195	199	PF00017	0.767
LIG_SH2_PTP2	241	244	PF00017	0.376
LIG_SH2_STAP1	195	199	PF00017	0.704
LIG_SH2_STAT5	230	233	PF00017	0.494
LIG_SH2_STAT5	241	244	PF00017	0.347
LIG_SH2_STAT5	3	6	PF00017	0.630
LIG_SH3_3	123	129	PF00018	0.635
LIG_TRAF2_1	173	176	PF00917	0.544
LIG_TRAF2_1	293	296	PF00917	0.335
LIG_WRC_WIRS_1	361	366	PF05994	0.315
MOD_CK1_1	100	106	PF00069	0.601
MOD_CK1_1	128	134	PF00069	0.733
MOD_CK1_1	167	173	PF00069	0.618
MOD_CK1_1	34	40	PF00069	0.628
MOD_CK2_1	382	388	PF00069	0.675
MOD_CK2_1	76	82	PF00069	0.481
MOD_DYRK1A_RPxSP_1	125	129	PF00069	0.612
MOD_DYRK1A_RPxSP_1	19	23	PF00069	0.667
MOD_GlcNHglycan	107	110	PF01048	0.697
MOD_GlcNHglycan	111	114	PF01048	0.618
MOD_GlcNHglycan	121	124	PF01048	0.709
MOD_GlcNHglycan	166	169	PF01048	0.666
MOD_GlcNHglycan	179	182	PF01048	0.528
MOD_GlcNHglycan	19	22	PF01048	0.592
MOD_GlcNHglycan	196	199	PF01048	0.623
MOD_GlcNHglycan	27	30	PF01048	0.640
MOD_GlcNHglycan	383	387	PF01048	0.597
MOD_GlcNHglycan	76	79	PF01048	0.674
MOD_GSK3_1	105	112	PF00069	0.679
MOD_GSK3_1	113	120	PF00069	0.629
MOD_GSK3_1	125	132	PF00069	0.640
MOD_GSK3_1	140	147	PF00069	0.553
MOD_GSK3_1	15	22	PF00069	0.581
MOD_GSK3_1	152	159	PF00069	0.598
MOD_GSK3_1	25	32	PF00069	0.622
MOD_GSK3_1	264	271	PF00069	0.459
MOD_GSK3_1	93	100	PF00069	0.565
MOD_LATS_1	156	162	PF00433	0.674
MOD_LATS_1	40	46	PF00433	0.604
MOD_N-GLC_1	100	105	PF02516	0.701
MOD_N-GLC_1	129	134	PF02516	0.661
MOD_N-GLC_1	152	157	PF02516	0.725
MOD_N-GLC_1	193	198	PF02516	0.651
MOD_N-GLC_1	264	269	PF02516	0.464
MOD_N-GLC_1	29	34	PF02516	0.633
MOD_NEK2_1	15	20	PF00069	0.579
MOD_NEK2_1	177	182	PF00069	0.574
MOD_NEK2_1	360	365	PF00069	0.315
MOD_NEK2_1	97	102	PF00069	0.584
MOD_NEK2_2	312	317	PF00069	0.315
MOD_PK_1	52	58	PF00069	0.564
MOD_PKA_1	339	345	PF00069	0.315
MOD_PKA_2	247	253	PF00069	0.390
MOD_PKA_2	74	80	PF00069	0.673
MOD_PKA_2	93	99	PF00069	0.411
MOD_Plk_1	100	106	PF00069	0.625
MOD_Plk_1	139	145	PF00069	0.659
MOD_Plk_1	264	270	PF00069	0.462
MOD_Plk_1	29	35	PF00069	0.627
MOD_Plk_1	347	353	PF00069	0.315
MOD_Plk_4	113	119	PF00069	0.525
MOD_Plk_4	42	48	PF00069	0.662
MOD_Plk_4	52	58	PF00069	0.462
MOD_Plk_4	59	65	PF00069	0.390
MOD_ProDKin_1	103	109	PF00069	0.616
MOD_ProDKin_1	125	131	PF00069	0.542
MOD_ProDKin_1	147	153	PF00069	0.659
MOD_ProDKin_1	19	25	PF00069	0.591
MOD_SUMO_for_1	282	285	PF00179	0.436
MOD_SUMO_rev_2	273	282	PF00179	0.456
MOD_SUMO_rev_2	331	341	PF00179	0.315
TRG_DiLeu_BaEn_2	214	220	PF01217	0.408
TRG_DiLeu_BaEn_4	205	211	PF01217	0.580
TRG_DiLeu_BaLyEn_6	49	54	PF01217	0.564
TRG_ENDOCYTIC_2	241	244	PF00928	0.376
TRG_ENDOCYTIC_2	361	364	PF00928	0.315
TRG_ER_diArg_1	224	227	PF00400	0.409
TRG_Pf-PMV_PEXEL_1	288	292	PF00026	0.395
TRG_Pf-PMV_PEXEL_1	354	359	PF00026	0.315

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I362	Leptomonas seymouri	67%	100%
A0A3Q8IEY4	Leishmania donovani	97%	100%
A4HMC6	Leishmania braziliensis	86%	99%
A4IAZ2	Leishmania infantum	97%	100%
E9AES0	Leishmania major	96%	100%