Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B5W0_LEIMU

TriTrypDb:

LmxM.34.0800

Length:

1012

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5W0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5W0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	533	537	PF00656	0.650
CLV_C14_Caspase3-7	619	623	PF00656	0.696
CLV_C14_Caspase3-7	748	752	PF00656	0.595
CLV_C14_Caspase3-7	930	934	PF00656	0.844
CLV_C14_Caspase3-7	942	946	PF00656	0.629
CLV_NRD_NRD_1	104	106	PF00675	0.740
CLV_NRD_NRD_1	23	25	PF00675	0.685
CLV_NRD_NRD_1	870	872	PF00675	0.755
CLV_NRD_NRD_1	98	100	PF00675	0.688
CLV_PCSK_KEX2_1	104	106	PF00082	0.751
CLV_PCSK_KEX2_1	23	25	PF00082	0.685
CLV_PCSK_KEX2_1	870	872	PF00082	0.755
CLV_PCSK_KEX2_1	965	967	PF00082	0.720
CLV_PCSK_KEX2_1	98	100	PF00082	0.688
CLV_PCSK_PC1ET2_1	965	967	PF00082	0.673
CLV_PCSK_SKI1_1	1004	1008	PF00082	0.733
CLV_PCSK_SKI1_1	417	421	PF00082	0.515
CLV_PCSK_SKI1_1	42	46	PF00082	0.653
CLV_PCSK_SKI1_1	673	677	PF00082	0.654
CLV_PCSK_SKI1_1	678	682	PF00082	0.645
CLV_PCSK_SKI1_1	788	792	PF00082	0.742
CLV_PCSK_SKI1_1	853	857	PF00082	0.829
CLV_PCSK_SKI1_1	91	95	PF00082	0.541
CLV_PCSK_SKI1_1	965	969	PF00082	0.669
CLV_Separin_Metazoa	952	956	PF03568	0.757
DEG_SPOP_SBC_1	178	182	PF00917	0.698
DEG_SPOP_SBC_1	243	247	PF00917	0.765
DEG_SPOP_SBC_1	798	802	PF00917	0.754
DOC_CKS1_1	152	157	PF01111	0.711
DOC_CKS1_1	470	475	PF01111	0.826
DOC_CKS1_1	731	736	PF01111	0.736
DOC_CYCLIN_RxL_1	39	49	PF00134	0.643
DOC_CYCLIN_RxL_1	88	97	PF00134	0.538
DOC_CYCLIN_yCln2_LP_2	458	464	PF00134	0.645
DOC_CYCLIN_yCln2_LP_2	550	556	PF00134	0.613
DOC_MAPK_DCC_7	916	926	PF00069	0.787
DOC_MAPK_gen_1	916	926	PF00069	0.763
DOC_MAPK_MEF2A_6	919	926	PF00069	0.772
DOC_PP2B_LxvP_1	420	423	PF13499	0.595
DOC_PP2B_LxvP_1	458	461	PF13499	0.744
DOC_PP2B_LxvP_1	908	911	PF13499	0.757
DOC_PP4_FxxP_1	86	89	PF00568	0.747
DOC_PP4_MxPP_1	829	832	PF00568	0.776
DOC_USP7_MATH_1	111	115	PF00917	0.676
DOC_USP7_MATH_1	144	148	PF00917	0.727
DOC_USP7_MATH_1	178	182	PF00917	0.814
DOC_USP7_MATH_1	243	247	PF00917	0.759
DOC_USP7_MATH_1	356	360	PF00917	0.797
DOC_USP7_MATH_1	411	415	PF00917	0.505
DOC_USP7_MATH_1	490	494	PF00917	0.594
DOC_USP7_MATH_1	582	586	PF00917	0.742
DOC_USP7_MATH_1	607	611	PF00917	0.736
DOC_USP7_MATH_1	639	643	PF00917	0.823
DOC_USP7_MATH_1	690	694	PF00917	0.826
DOC_USP7_MATH_1	696	700	PF00917	0.736
DOC_USP7_MATH_1	750	754	PF00917	0.708
DOC_USP7_MATH_1	756	760	PF00917	0.748
DOC_USP7_MATH_1	78	82	PF00917	0.582
DOC_USP7_MATH_1	810	814	PF00917	0.771
DOC_USP7_MATH_1	860	864	PF00917	0.648
DOC_USP7_MATH_1	929	933	PF00917	0.793
DOC_USP7_MATH_1	956	960	PF00917	0.559
DOC_WW_Pin1_4	151	156	PF00397	0.712
DOC_WW_Pin1_4	199	204	PF00397	0.747
DOC_WW_Pin1_4	245	250	PF00397	0.729
DOC_WW_Pin1_4	313	318	PF00397	0.829
DOC_WW_Pin1_4	469	474	PF00397	0.825
DOC_WW_Pin1_4	486	491	PF00397	0.539
DOC_WW_Pin1_4	541	546	PF00397	0.731
DOC_WW_Pin1_4	549	554	PF00397	0.620
DOC_WW_Pin1_4	577	582	PF00397	0.641
DOC_WW_Pin1_4	720	725	PF00397	0.806
DOC_WW_Pin1_4	730	735	PF00397	0.661
DOC_WW_Pin1_4	746	751	PF00397	0.640
DOC_WW_Pin1_4	758	763	PF00397	0.583
DOC_WW_Pin1_4	834	839	PF00397	0.552
DOC_WW_Pin1_4	903	908	PF00397	0.614
DOC_WW_Pin1_4	917	922	PF00397	0.806
DOC_WW_Pin1_4	987	992	PF00397	0.729
LIG_14-3-3_CanoR_1	31	37	PF00244	0.618
LIG_14-3-3_CanoR_1	345	353	PF00244	0.815
LIG_14-3-3_CanoR_1	484	490	PF00244	0.531
LIG_14-3-3_CanoR_1	602	607	PF00244	0.738
LIG_14-3-3_CanoR_1	640	646	PF00244	0.634
LIG_14-3-3_CanoR_1	714	724	PF00244	0.824
LIG_14-3-3_CanoR_1	788	797	PF00244	0.745
LIG_14-3-3_CanoR_1	83	89	PF00244	0.761
LIG_14-3-3_CanoR_1	886	893	PF00244	0.548
LIG_14-3-3_CanoR_1	98	106	PF00244	0.634
LIG_14-3-3_CanoR_1	982	991	PF00244	0.750
LIG_Actin_WH2_2	413	431	PF00022	0.519
LIG_Actin_WH2_2	7	25	PF00022	0.675
LIG_BIR_II_1	1	5	PF00653	0.777
LIG_BIR_III_3	1	5	PF00653	0.777
LIG_BIR_III_4	273	277	PF00653	0.793
LIG_BRCT_BRCA1_1	543	547	PF00533	0.712
LIG_BRCT_BRCA1_1	782	786	PF00533	0.816
LIG_BRCT_BRCA1_1	985	989	PF00533	0.746
LIG_deltaCOP1_diTrp_1	378	386	PF00928	0.754
LIG_deltaCOP1_diTrp_1	781	786	PF00928	0.817
LIG_FHA_1	178	184	PF00498	0.699
LIG_FHA_1	263	269	PF00498	0.645
LIG_FHA_1	36	42	PF00498	0.674
LIG_FHA_1	498	504	PF00498	0.821
LIG_FHA_1	52	58	PF00498	0.424
LIG_FHA_1	619	625	PF00498	0.620
LIG_FHA_1	773	779	PF00498	0.775
LIG_FHA_1	789	795	PF00498	0.620
LIG_FHA_1	888	894	PF00498	0.543
LIG_FHA_1	95	101	PF00498	0.827
LIG_FHA_2	152	158	PF00498	0.784
LIG_FHA_2	249	255	PF00498	0.558
LIG_FHA_2	533	539	PF00498	0.667
LIG_FHA_2	742	748	PF00498	0.793
LIG_FHA_2	835	841	PF00498	0.547
LIG_FHA_2	938	944	PF00498	0.622
LIG_FHA_2	946	952	PF00498	0.580
LIG_Integrin_RGD_1	771	773	PF01839	0.860
LIG_LIR_Apic_2	733	739	PF02991	0.638
LIG_LIR_Apic_2	913	917	PF02991	0.744
LIG_LIR_Gen_1	781	792	PF02991	0.818
LIG_LIR_Nem_3	147	152	PF02991	0.645
LIG_LIR_Nem_3	378	383	PF02991	0.754
LIG_LIR_Nem_3	544	550	PF02991	0.709
LIG_LIR_Nem_3	781	787	PF02991	0.817
LIG_RPA_C_Fungi	346	358	PF08784	0.522
LIG_SH2_CRK	845	849	PF00017	0.537
LIG_SH2_GRB2like	37	40	PF00017	0.676
LIG_SH2_NCK_1	5	9	PF00017	0.634
LIG_SH2_SRC	462	465	PF00017	0.646
LIG_SH2_STAP1	37	41	PF00017	0.671
LIG_SH2_STAT3	13	16	PF00017	0.601
LIG_SH2_STAT3	232	235	PF00017	0.828
LIG_SH2_STAT3	626	629	PF00017	0.540
LIG_SH2_STAT5	13	16	PF00017	0.499
LIG_SH2_STAT5	327	330	PF00017	0.655
LIG_SH2_STAT5	37	40	PF00017	0.676
LIG_SH2_STAT5	462	465	PF00017	0.724
LIG_SH2_STAT5	5	8	PF00017	0.637
LIG_SH2_STAT5	51	54	PF00017	0.434
LIG_SH2_STAT5	592	595	PF00017	0.636
LIG_SH2_STAT5	847	850	PF00017	0.634
LIG_SH3_1	315	321	PF00018	0.835
LIG_SH3_2	317	322	PF14604	0.657
LIG_SH3_3	314	320	PF00018	0.831
LIG_SH3_3	360	366	PF00018	0.508
LIG_SH3_3	442	448	PF00018	0.679
LIG_SH3_3	458	464	PF00018	0.582
LIG_SH3_3	470	476	PF00018	0.674
LIG_SH3_3	54	60	PF00018	0.702
LIG_SH3_3	576	582	PF00018	0.687
LIG_SH3_3	584	590	PF00018	0.589
LIG_SH3_3	593	599	PF00018	0.571
LIG_SH3_3	633	639	PF00018	0.714
LIG_SH3_3	718	724	PF00018	0.838
LIG_SH3_3	731	737	PF00018	0.642
LIG_SUMO_SIM_anti_2	442	447	PF11976	0.536
LIG_SUMO_SIM_par_1	288	295	PF11976	0.715
LIG_WRC_WIRS_1	383	388	PF05994	0.633
LIG_WW_3	830	834	PF00397	0.663
LIG_WW_3	88	92	PF00397	0.751
MOD_CDK_SPK_2	834	839	PF00069	0.552
MOD_CK1_1	135	141	PF00069	0.741
MOD_CK1_1	187	193	PF00069	0.648
MOD_CK1_1	198	204	PF00069	0.766
MOD_CK1_1	218	224	PF00069	0.727
MOD_CK1_1	226	232	PF00069	0.710
MOD_CK1_1	234	240	PF00069	0.575
MOD_CK1_1	245	251	PF00069	0.818
MOD_CK1_1	281	287	PF00069	0.709
MOD_CK1_1	346	352	PF00069	0.671
MOD_CK1_1	361	367	PF00069	0.578
MOD_CK1_1	401	407	PF00069	0.702
MOD_CK1_1	465	471	PF00069	0.812
MOD_CK1_1	499	505	PF00069	0.732
MOD_CK1_1	532	538	PF00069	0.701
MOD_CK1_1	817	823	PF00069	0.765
MOD_CK1_1	876	882	PF00069	0.826
MOD_CK1_1	885	891	PF00069	0.691
MOD_CK1_1	959	965	PF00069	0.558
MOD_CK1_1	984	990	PF00069	0.643
MOD_CK2_1	151	157	PF00069	0.786
MOD_CK2_1	221	227	PF00069	0.734
MOD_CK2_1	386	392	PF00069	0.584
MOD_CK2_1	532	538	PF00069	0.670
MOD_CK2_1	696	702	PF00069	0.544
MOD_CK2_1	758	764	PF00069	0.745
MOD_CK2_1	834	840	PF00069	0.550
MOD_CK2_1	885	891	PF00069	0.548
MOD_CK2_1	945	951	PF00069	0.837
MOD_Cter_Amidation	102	105	PF01082	0.752
MOD_Cter_Amidation	963	966	PF01082	0.739
MOD_DYRK1A_RPxSP_1	758	762	PF00069	0.672
MOD_GlcNHglycan	107	110	PF01048	0.704
MOD_GlcNHglycan	111	114	PF01048	0.707
MOD_GlcNHglycan	118	121	PF01048	0.751
MOD_GlcNHglycan	141	144	PF01048	0.778
MOD_GlcNHglycan	146	149	PF01048	0.693
MOD_GlcNHglycan	161	164	PF01048	0.494
MOD_GlcNHglycan	172	175	PF01048	0.636
MOD_GlcNHglycan	270	273	PF01048	0.756
MOD_GlcNHglycan	283	286	PF01048	0.630
MOD_GlcNHglycan	294	297	PF01048	0.619
MOD_GlcNHglycan	338	341	PF01048	0.808
MOD_GlcNHglycan	354	357	PF01048	0.549
MOD_GlcNHglycan	358	361	PF01048	0.483
MOD_GlcNHglycan	403	406	PF01048	0.762
MOD_GlcNHglycan	413	416	PF01048	0.638
MOD_GlcNHglycan	435	438	PF01048	0.749
MOD_GlcNHglycan	439	442	PF01048	0.803
MOD_GlcNHglycan	478	481	PF01048	0.757
MOD_GlcNHglycan	492	496	PF01048	0.574
MOD_GlcNHglycan	513	516	PF01048	0.620
MOD_GlcNHglycan	641	644	PF01048	0.817
MOD_GlcNHglycan	688	691	PF01048	0.803
MOD_GlcNHglycan	692	695	PF01048	0.786
MOD_GlcNHglycan	707	710	PF01048	0.730
MOD_GlcNHglycan	717	720	PF01048	0.700
MOD_GlcNHglycan	751	755	PF01048	0.855
MOD_GlcNHglycan	86	89	PF01048	0.751
MOD_GlcNHglycan	862	865	PF01048	0.643
MOD_GlcNHglycan	866	869	PF01048	0.629
MOD_GlcNHglycan	887	890	PF01048	0.608
MOD_GlcNHglycan	929	932	PF01048	0.751
MOD_GSK3_1	105	112	PF00069	0.809
MOD_GSK3_1	116	123	PF00069	0.644
MOD_GSK3_1	131	138	PF00069	0.711
MOD_GSK3_1	192	199	PF00069	0.740
MOD_GSK3_1	231	238	PF00069	0.825
MOD_GSK3_1	243	250	PF00069	0.565
MOD_GSK3_1	264	271	PF00069	0.688
MOD_GSK3_1	3	10	PF00069	0.714
MOD_GSK3_1	341	348	PF00069	0.693
MOD_GSK3_1	352	359	PF00069	0.586
MOD_GSK3_1	382	389	PF00069	0.727
MOD_GSK3_1	390	397	PF00069	0.644
MOD_GSK3_1	433	440	PF00069	0.679
MOD_GSK3_1	462	469	PF00069	0.747
MOD_GSK3_1	486	493	PF00069	0.796
MOD_GSK3_1	497	504	PF00069	0.667
MOD_GSK3_1	539	546	PF00069	0.691
MOD_GSK3_1	653	660	PF00069	0.613
MOD_GSK3_1	682	689	PF00069	0.698
MOD_GSK3_1	705	712	PF00069	0.839
MOD_GSK3_1	746	753	PF00069	0.724
MOD_GSK3_1	788	795	PF00069	0.681
MOD_GSK3_1	805	812	PF00069	0.534
MOD_GSK3_1	860	867	PF00069	0.643
MOD_GSK3_1	876	883	PF00069	0.709
MOD_GSK3_1	94	101	PF00069	0.701
MOD_GSK3_1	983	990	PF00069	0.842
MOD_N-GLC_1	135	140	PF02516	0.723
MOD_N-GLC_1	215	220	PF02516	0.645
MOD_N-GLC_1	263	268	PF02516	0.529
MOD_N-GLC_1	300	305	PF02516	0.635
MOD_N-GLC_1	432	437	PF02516	0.732
MOD_N-GLC_1	496	501	PF02516	0.532
MOD_N-GLC_1	880	885	PF02516	0.758
MOD_N-GLC_1	945	950	PF02516	0.835
MOD_N-GLC_1	987	992	PF02516	0.729
MOD_N-GLC_2	166	168	PF02516	0.750
MOD_NEK2_1	1005	1010	PF00069	0.750
MOD_NEK2_1	196	201	PF00069	0.807
MOD_NEK2_1	231	236	PF00069	0.827
MOD_NEK2_1	336	341	PF00069	0.697
MOD_NEK2_1	343	348	PF00069	0.683
MOD_NEK2_1	386	391	PF00069	0.585
MOD_NEK2_1	491	496	PF00069	0.635
MOD_NEK2_1	676	681	PF00069	0.767
MOD_NEK2_1	94	99	PF00069	0.799
MOD_NEK2_2	179	184	PF00069	0.698
MOD_PIKK_1	231	237	PF00454	0.825
MOD_PIKK_1	972	978	PF00454	0.749
MOD_PIKK_1	98	104	PF00454	0.785
MOD_PK_1	308	314	PF00069	0.665
MOD_PKA_1	98	104	PF00069	0.604
MOD_PKA_2	159	165	PF00069	0.745
MOD_PKA_2	30	36	PF00069	0.680
MOD_PKA_2	639	645	PF00069	0.674
MOD_PKA_2	817	823	PF00069	0.862
MOD_PKA_2	860	866	PF00069	0.650
MOD_PKA_2	885	891	PF00069	0.558
MOD_PKA_2	956	962	PF00069	0.714
MOD_PKA_2	98	104	PF00069	0.682
MOD_PKA_2	981	987	PF00069	0.785
MOD_PKB_1	306	314	PF00069	0.661
MOD_Plk_1	135	141	PF00069	0.642
MOD_Plk_1	215	221	PF00069	0.690
MOD_Plk_1	226	232	PF00069	0.652
MOD_Plk_1	263	269	PF00069	0.532
MOD_Plk_1	676	682	PF00069	0.579
MOD_Plk_1	780	786	PF00069	0.673
MOD_Plk_2-3	278	284	PF00069	0.784
MOD_Plk_4	135	141	PF00069	0.545
MOD_Plk_4	226	232	PF00069	0.815
MOD_Plk_4	264	270	PF00069	0.691
MOD_Plk_4	382	388	PF00069	0.632
MOD_Plk_4	893	899	PF00069	0.823
MOD_Plk_4	910	916	PF00069	0.566
MOD_ProDKin_1	151	157	PF00069	0.711
MOD_ProDKin_1	199	205	PF00069	0.750
MOD_ProDKin_1	245	251	PF00069	0.731
MOD_ProDKin_1	313	319	PF00069	0.827
MOD_ProDKin_1	469	475	PF00069	0.827
MOD_ProDKin_1	486	492	PF00069	0.541
MOD_ProDKin_1	541	547	PF00069	0.731
MOD_ProDKin_1	549	555	PF00069	0.614
MOD_ProDKin_1	577	583	PF00069	0.643
MOD_ProDKin_1	720	726	PF00069	0.804
MOD_ProDKin_1	730	736	PF00069	0.664
MOD_ProDKin_1	746	752	PF00069	0.641
MOD_ProDKin_1	758	764	PF00069	0.586
MOD_ProDKin_1	834	840	PF00069	0.550
MOD_ProDKin_1	903	909	PF00069	0.614
MOD_ProDKin_1	917	923	PF00069	0.808
MOD_ProDKin_1	987	993	PF00069	0.720
TRG_DiLeu_BaEn_1	664	669	PF01217	0.640
TRG_DiLeu_BaEn_1	995	1000	PF01217	0.707
TRG_DiLeu_BaEn_2	381	387	PF01217	0.745
TRG_DiLeu_BaLyEn_6	420	425	PF01217	0.522
TRG_ENDOCYTIC_2	845	848	PF00928	0.538
TRG_ER_diArg_1	1002	1005	PF00400	0.718
TRG_ER_diArg_1	104	106	PF00400	0.617
TRG_ER_diArg_1	22	24	PF00400	0.685
TRG_ER_diArg_1	870	872	PF00400	0.755
TRG_ER_diArg_1	954	957	PF00400	0.835
TRG_ER_diArg_1	98	100	PF00400	0.718
TRG_Pf-PMV_PEXEL_1	966	970	PF00026	0.667

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X8V2	Leishmania donovani	79%	100%
A4HMB1	Leishmania braziliensis	59%	94%
A4IAX7	Leishmania infantum	79%	100%
E9AEQ5	Leishmania major	80%	99%