Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B5V8_LEIMU

TriTrypDb:

LmxM.34.0780

Length:

790

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5V8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5V8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	77	81	PF00656	0.563
CLV_NRD_NRD_1	138	140	PF00675	0.618
CLV_NRD_NRD_1	176	178	PF00675	0.590
CLV_NRD_NRD_1	200	202	PF00675	0.617
CLV_NRD_NRD_1	209	211	PF00675	0.773
CLV_NRD_NRD_1	423	425	PF00675	0.548
CLV_NRD_NRD_1	462	464	PF00675	0.724
CLV_NRD_NRD_1	718	720	PF00675	0.738
CLV_NRD_NRD_1	754	756	PF00675	0.582
CLV_PCSK_FUR_1	198	202	PF00082	0.582
CLV_PCSK_KEX2_1	140	142	PF00082	0.831
CLV_PCSK_KEX2_1	176	178	PF00082	0.840
CLV_PCSK_KEX2_1	200	202	PF00082	0.617
CLV_PCSK_KEX2_1	209	211	PF00082	0.773
CLV_PCSK_KEX2_1	376	378	PF00082	0.559
CLV_PCSK_KEX2_1	423	425	PF00082	0.548
CLV_PCSK_KEX2_1	461	463	PF00082	0.725
CLV_PCSK_KEX2_1	543	545	PF00082	0.436
CLV_PCSK_KEX2_1	648	650	PF00082	0.861
CLV_PCSK_KEX2_1	718	720	PF00082	0.738
CLV_PCSK_KEX2_1	754	756	PF00082	0.582
CLV_PCSK_PC1ET2_1	140	142	PF00082	0.831
CLV_PCSK_PC1ET2_1	376	378	PF00082	0.587
CLV_PCSK_PC1ET2_1	543	545	PF00082	0.436
CLV_PCSK_PC1ET2_1	648	650	PF00082	0.861
CLV_PCSK_SKI1_1	117	121	PF00082	0.836
CLV_PCSK_SKI1_1	140	144	PF00082	0.830
CLV_PCSK_SKI1_1	216	220	PF00082	0.601
CLV_PCSK_SKI1_1	337	341	PF00082	0.522
CLV_PCSK_SKI1_1	376	380	PF00082	0.569
CLV_PCSK_SKI1_1	418	422	PF00082	0.667
CLV_PCSK_SKI1_1	438	442	PF00082	0.307
CLV_PCSK_SKI1_1	510	514	PF00082	0.415
CLV_PCSK_SKI1_1	615	619	PF00082	0.566
DEG_APCC_DBOX_1	519	527	PF00400	0.570
DEG_Kelch_Keap1_1	222	227	PF01344	0.579
DEG_SPOP_SBC_1	218	222	PF00917	0.600
DOC_ANK_TNKS_1	178	185	PF00023	0.835
DOC_CKS1_1	124	129	PF01111	0.608
DOC_CKS1_1	468	473	PF01111	0.848
DOC_CYCLIN_RxL_1	612	619	PF00134	0.815
DOC_CYCLIN_yCln2_LP_2	668	674	PF00134	0.793
DOC_MAPK_DCC_7	461	469	PF00069	0.836
DOC_MAPK_gen_1	337	347	PF00069	0.496
DOC_MAPK_gen_1	461	469	PF00069	0.836
DOC_MAPK_gen_1	718	726	PF00069	0.590
DOC_MAPK_gen_1	761	768	PF00069	0.552
DOC_MAPK_MEF2A_6	255	262	PF00069	0.662
DOC_MAPK_MEF2A_6	461	469	PF00069	0.836
DOC_MAPK_NFAT4_5	255	263	PF00069	0.662
DOC_PP1_RVXF_1	717	724	PF00149	0.676
DOC_PP2B_LxvP_1	163	166	PF13499	0.832
DOC_PP2B_LxvP_1	691	694	PF13499	0.704
DOC_PP4_FxxP_1	142	145	PF00568	0.703
DOC_USP7_MATH_1	108	112	PF00917	0.821
DOC_USP7_MATH_1	218	222	PF00917	0.746
DOC_USP7_MATH_1	493	497	PF00917	0.703
DOC_USP7_MATH_1	644	648	PF00917	0.748
DOC_USP7_MATH_1	696	700	PF00917	0.763
DOC_USP7_MATH_1	735	739	PF00917	0.569
DOC_USP7_MATH_1	774	778	PF00917	0.771
DOC_USP7_MATH_1	78	82	PF00917	0.785
DOC_USP7_UBL2_3	136	140	PF12436	0.726
DOC_USP7_UBL2_3	372	376	PF12436	0.554
DOC_USP7_UBL2_3	637	641	PF12436	0.571
DOC_WW_Pin1_4	104	109	PF00397	0.813
DOC_WW_Pin1_4	123	128	PF00397	0.511
DOC_WW_Pin1_4	141	146	PF00397	0.771
DOC_WW_Pin1_4	161	166	PF00397	0.490
DOC_WW_Pin1_4	219	224	PF00397	0.690
DOC_WW_Pin1_4	289	294	PF00397	0.830
DOC_WW_Pin1_4	302	307	PF00397	0.447
DOC_WW_Pin1_4	34	39	PF00397	0.697
DOC_WW_Pin1_4	467	472	PF00397	0.835
DOC_WW_Pin1_4	477	482	PF00397	0.650
DOC_WW_Pin1_4	605	610	PF00397	0.800
DOC_WW_Pin1_4	777	782	PF00397	0.765
LIG_14-3-3_CanoR_1	139	145	PF00244	0.764
LIG_14-3-3_CanoR_1	232	238	PF00244	0.660
LIG_14-3-3_CanoR_1	607	617	PF00244	0.717
LIG_14-3-3_CanoR_1	649	655	PF00244	0.851
LIG_14-3-3_CanoR_1	712	721	PF00244	0.603
LIG_14-3-3_CanoR_1	776	781	PF00244	0.566
LIG_Actin_WH2_2	357	374	PF00022	0.539
LIG_Actin_WH2_2	686	704	PF00022	0.814
LIG_BIR_II_1	1	5	PF00653	0.654
LIG_BRCT_BRCA1_1	240	244	PF00533	0.601
LIG_EVH1_2	21	25	PF00568	0.801
LIG_FHA_1	105	111	PF00498	0.752
LIG_FHA_1	223	229	PF00498	0.820
LIG_FHA_1	233	239	PF00498	0.594
LIG_FHA_1	243	249	PF00498	0.571
LIG_FHA_1	298	304	PF00498	0.809
LIG_FHA_1	549	555	PF00498	0.748
LIG_FHA_1	696	702	PF00498	0.560
LIG_FHA_2	148	154	PF00498	0.846
LIG_FHA_2	409	415	PF00498	0.600
LIG_FHA_2	528	534	PF00498	0.501
LIG_FHA_2	625	631	PF00498	0.565
LIG_Integrin_isoDGR_2	34	36	PF01839	0.567
LIG_LIR_Apic_2	47	53	PF02991	0.574
LIG_LIR_Gen_1	12	22	PF02991	0.554
LIG_LIR_Gen_1	321	330	PF02991	0.677
LIG_LIR_Gen_1	571	576	PF02991	0.510
LIG_LIR_Gen_1	616	623	PF02991	0.696
LIG_LIR_Nem_3	12	18	PF02991	0.557
LIG_LIR_Nem_3	321	325	PF02991	0.699
LIG_LIR_Nem_3	571	575	PF02991	0.507
LIG_LIR_Nem_3	616	621	PF02991	0.696
LIG_LIR_Nem_3	722	726	PF02991	0.537
LIG_LIR_Nem_3	86	92	PF02991	0.582
LIG_PCNA_yPIPBox_3	337	351	PF02747	0.524
LIG_PCNA_yPIPBox_3	355	365	PF02747	0.642
LIG_PTAP_UEV_1	179	184	PF05743	0.833
LIG_SH2_CRK	351	355	PF00017	0.516
LIG_SH2_SRC	274	277	PF00017	0.417
LIG_SH2_SRC	50	53	PF00017	0.571
LIG_SH2_STAP1	26	30	PF00017	0.825
LIG_SH2_STAP1	322	326	PF00017	0.573
LIG_SH2_STAP1	639	643	PF00017	0.583
LIG_SH2_STAP1	85	89	PF00017	0.544
LIG_SH2_STAT3	3	6	PF00017	0.767
LIG_SH2_STAT3	639	642	PF00017	0.580
LIG_SH2_STAT5	667	670	PF00017	0.757
LIG_SH2_STAT5	85	88	PF00017	0.594
LIG_SH3_1	177	183	PF00018	0.833
LIG_SH3_1	462	468	PF00018	0.834
LIG_SH3_2	468	473	PF14604	0.598
LIG_SH3_3	15	21	PF00018	0.806
LIG_SH3_3	177	183	PF00018	0.833
LIG_SH3_3	300	306	PF00018	0.802
LIG_SH3_3	462	468	PF00018	0.734
LIG_SH3_3	652	658	PF00018	0.595
LIG_SxIP_EBH_1	763	777	PF03271	0.550
LIG_TRAF2_1	356	359	PF00917	0.636
LIG_TRAF2_1	530	533	PF00917	0.555
LIG_TRAF2_1	587	590	PF00917	0.539
LIG_TRAF2_1	683	686	PF00917	0.814
LIG_TYR_ITIM	13	18	PF00017	0.760
LIG_WRC_WIRS_1	720	725	PF05994	0.538
LIG_WW_2	465	468	PF00397	0.832
LIG_WW_3	165	169	PF00397	0.826
MOD_CDK_SPK_2	123	128	PF00069	0.778
MOD_CDK_SPK_2	477	482	PF00069	0.844
MOD_CDK_SPxK_1	34	40	PF00069	0.699
MOD_CDK_SPxK_1	467	473	PF00069	0.597
MOD_CDK_SPxxK_3	161	168	PF00069	0.836
MOD_CK1_1	144	150	PF00069	0.833
MOD_CK1_1	192	198	PF00069	0.786
MOD_CK1_1	221	227	PF00069	0.815
MOD_CK1_1	236	242	PF00069	0.574
MOD_CK1_1	302	308	PF00069	0.765
MOD_CK1_1	476	482	PF00069	0.722
MOD_CK1_1	531	537	PF00069	0.557
MOD_CK1_1	558	564	PF00069	0.696
MOD_CK1_1	605	611	PF00069	0.737
MOD_CK1_1	64	70	PF00069	0.556
MOD_CK1_1	708	714	PF00069	0.692
MOD_CK1_1	71	77	PF00069	0.559
MOD_CK1_1	777	783	PF00069	0.809
MOD_CK2_1	147	153	PF00069	0.844
MOD_CK2_1	221	227	PF00069	0.582
MOD_CK2_1	408	414	PF00069	0.608
MOD_CK2_1	527	533	PF00069	0.505
MOD_CK2_1	583	589	PF00069	0.644
MOD_CK2_1	624	630	PF00069	0.563
MOD_CK2_1	737	743	PF00069	0.597
MOD_Cter_Amidation	198	201	PF01082	0.592
MOD_GlcNHglycan	110	113	PF01048	0.655
MOD_GlcNHglycan	180	183	PF01048	0.742
MOD_GlcNHglycan	203	206	PF01048	0.846
MOD_GlcNHglycan	227	231	PF01048	0.700
MOD_GlcNHglycan	238	241	PF01048	0.664
MOD_GlcNHglycan	28	31	PF01048	0.783
MOD_GlcNHglycan	393	396	PF01048	0.641
MOD_GlcNHglycan	454	457	PF01048	0.682
MOD_GlcNHglycan	495	498	PF01048	0.687
MOD_GlcNHglycan	558	561	PF01048	0.692
MOD_GlcNHglycan	565	568	PF01048	0.623
MOD_GlcNHglycan	58	61	PF01048	0.702
MOD_GlcNHglycan	580	583	PF01048	0.687
MOD_GlcNHglycan	585	588	PF01048	0.658
MOD_GlcNHglycan	672	675	PF01048	0.795
MOD_GlcNHglycan	71	74	PF01048	0.791
MOD_GlcNHglycan	714	717	PF01048	0.671
MOD_GlcNHglycan	755	758	PF01048	0.717
MOD_GlcNHglycan	76	79	PF01048	0.752
MOD_GlcNHglycan	787	790	PF01048	0.678
MOD_GlcNHglycan	98	101	PF01048	0.717
MOD_GSK3_1	104	111	PF00069	0.716
MOD_GSK3_1	140	147	PF00069	0.714
MOD_GSK3_1	217	224	PF00069	0.791
MOD_GSK3_1	228	235	PF00069	0.626
MOD_GSK3_1	236	243	PF00069	0.673
MOD_GSK3_1	280	287	PF00069	0.655
MOD_GSK3_1	295	302	PF00069	0.618
MOD_GSK3_1	472	479	PF00069	0.732
MOD_GSK3_1	527	534	PF00069	0.559
MOD_GSK3_1	556	563	PF00069	0.798
MOD_GSK3_1	597	604	PF00069	0.690
MOD_GSK3_1	605	612	PF00069	0.789
MOD_GSK3_1	64	71	PF00069	0.695
MOD_GSK3_1	701	708	PF00069	0.717
MOD_GSK3_1	74	81	PF00069	0.630
MOD_GSK3_1	766	773	PF00069	0.687
MOD_N-GLC_1	476	481	PF02516	0.843
MOD_N-GLC_1	556	561	PF02516	0.715
MOD_N-GLC_1	64	69	PF02516	0.576
MOD_NEK2_1	135	140	PF00069	0.725
MOD_NEK2_1	189	194	PF00069	0.712
MOD_NEK2_1	228	233	PF00069	0.651
MOD_NEK2_1	238	243	PF00069	0.569
MOD_NEK2_1	299	304	PF00069	0.808
MOD_NEK2_1	350	355	PF00069	0.520
MOD_NEK2_1	378	383	PF00069	0.575
MOD_NEK2_1	45	50	PF00069	0.580
MOD_NEK2_1	555	560	PF00069	0.797
MOD_NEK2_1	601	606	PF00069	0.640
MOD_NEK2_1	613	618	PF00069	0.721
MOD_NEK2_1	63	68	PF00069	0.489
MOD_NEK2_1	701	706	PF00069	0.699
MOD_PIKK_1	233	239	PF00454	0.769
MOD_PIKK_1	280	286	PF00454	0.549
MOD_PIKK_1	418	424	PF00454	0.668
MOD_PIKK_1	45	51	PF00454	0.581
MOD_PKA_1	140	146	PF00069	0.827
MOD_PKA_2	140	146	PF00069	0.731
MOD_PKA_2	178	184	PF00069	0.752
MOD_PKA_2	208	214	PF00069	0.608
MOD_PKA_2	231	237	PF00069	0.664
MOD_PKA_2	318	324	PF00069	0.737
MOD_PKA_2	452	458	PF00069	0.771
MOD_PKA_2	472	478	PF00069	0.646
MOD_PKA_2	69	75	PF00069	0.583
MOD_PKA_2	701	707	PF00069	0.718
MOD_PKA_2	711	717	PF00069	0.654
MOD_PKA_2	753	759	PF00069	0.569
MOD_PKA_2	775	781	PF00069	0.564
MOD_Plk_1	64	70	PF00069	0.578
MOD_Plk_2-3	318	324	PF00069	0.737
MOD_Plk_2-3	737	743	PF00069	0.597
MOD_Plk_4	299	305	PF00069	0.743
MOD_Plk_4	571	577	PF00069	0.760
MOD_Plk_4	597	603	PF00069	0.577
MOD_Plk_4	719	725	PF00069	0.539
MOD_Plk_4	91	97	PF00069	0.631
MOD_ProDKin_1	104	110	PF00069	0.813
MOD_ProDKin_1	123	129	PF00069	0.512
MOD_ProDKin_1	141	147	PF00069	0.771
MOD_ProDKin_1	161	167	PF00069	0.485
MOD_ProDKin_1	219	225	PF00069	0.688
MOD_ProDKin_1	289	295	PF00069	0.829
MOD_ProDKin_1	302	308	PF00069	0.447
MOD_ProDKin_1	34	40	PF00069	0.699
MOD_ProDKin_1	467	473	PF00069	0.838
MOD_ProDKin_1	477	483	PF00069	0.650
MOD_ProDKin_1	605	611	PF00069	0.799
MOD_ProDKin_1	777	783	PF00069	0.765
MOD_SUMO_for_1	513	516	PF00179	0.549
TRG_DiLeu_BaEn_1	571	576	PF01217	0.643
TRG_DiLeu_BaLyEn_6	130	135	PF01217	0.580
TRG_ENDOCYTIC_2	15	18	PF00928	0.764
TRG_ENDOCYTIC_2	322	325	PF00928	0.580
TRG_ENDOCYTIC_2	351	354	PF00928	0.520
TRG_ENDOCYTIC_2	89	92	PF00928	0.540
TRG_ER_diArg_1	139	142	PF00400	0.583
TRG_ER_diArg_1	176	179	PF00400	0.828
TRG_ER_diArg_1	197	200	PF00400	0.590
TRG_ER_diArg_1	423	425	PF00400	0.548
TRG_ER_diArg_1	443	446	PF00400	0.324
TRG_ER_diArg_1	461	463	PF00400	0.492
TRG_ER_diArg_1	718	720	PF00400	0.744
TRG_ER_diArg_1	753	755	PF00400	0.588
TRG_ER_diArg_1	8	11	PF00400	0.552
TRG_NLS_MonoExtN_4	136	143	PF00514	0.588
TRG_Pf-PMV_PEXEL_1	168	172	PF00026	0.843
TRG_Pf-PMV_PEXEL_1	201	206	PF00026	0.836
TRG_Pf-PMV_PEXEL_1	249	253	PF00026	0.418
TRG_Pf-PMV_PEXEL_1	337	341	PF00026	0.389
TRG_Pf-PMV_PEXEL_1	424	428	PF00026	0.542

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4N2	Leptomonas seymouri	40%	93%
E9AEQ3	Leishmania major	80%	98%