LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B5V4_LEIMU
TriTrypDb:
LmxM.34.0740
Length:
925

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5V4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5V4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 163 167 PF00656 0.537
CLV_C14_Caspase3-7 238 242 PF00656 0.679
CLV_C14_Caspase3-7 250 254 PF00656 0.649
CLV_C14_Caspase3-7 763 767 PF00656 0.506
CLV_C14_Caspase3-7 831 835 PF00656 0.813
CLV_NRD_NRD_1 2 4 PF00675 0.712
CLV_NRD_NRD_1 312 314 PF00675 0.671
CLV_NRD_NRD_1 643 645 PF00675 0.632
CLV_NRD_NRD_1 7 9 PF00675 0.711
CLV_NRD_NRD_1 710 712 PF00675 0.704
CLV_NRD_NRD_1 860 862 PF00675 0.742
CLV_NRD_NRD_1 863 865 PF00675 0.712
CLV_NRD_NRD_1 872 874 PF00675 0.713
CLV_NRD_NRD_1 875 877 PF00675 0.700
CLV_PCSK_FUR_1 861 865 PF00082 0.817
CLV_PCSK_FUR_1 873 877 PF00082 0.641
CLV_PCSK_KEX2_1 312 314 PF00082 0.671
CLV_PCSK_KEX2_1 531 533 PF00082 0.821
CLV_PCSK_KEX2_1 643 645 PF00082 0.632
CLV_PCSK_KEX2_1 678 680 PF00082 0.731
CLV_PCSK_KEX2_1 710 712 PF00082 0.704
CLV_PCSK_KEX2_1 862 864 PF00082 0.758
CLV_PCSK_KEX2_1 874 876 PF00082 0.826
CLV_PCSK_PC1ET2_1 531 533 PF00082 0.821
CLV_PCSK_PC1ET2_1 678 680 PF00082 0.731
CLV_PCSK_PC1ET2_1 862 864 PF00082 0.758
CLV_PCSK_PC1ET2_1 874 876 PF00082 0.826
CLV_PCSK_SKI1_1 471 475 PF00082 0.644
CLV_PCSK_SKI1_1 503 507 PF00082 0.671
CLV_PCSK_SKI1_1 914 918 PF00082 0.745
DEG_APCC_DBOX_1 475 483 PF00400 0.577
DEG_SPOP_SBC_1 290 294 PF00917 0.739
DOC_CDC14_PxL_1 131 139 PF14671 0.569
DOC_CKS1_1 175 180 PF01111 0.437
DOC_CKS1_1 380 385 PF01111 0.545
DOC_CKS1_1 438 443 PF01111 0.717
DOC_CKS1_1 490 495 PF01111 0.650
DOC_CKS1_1 52 57 PF01111 0.710
DOC_CKS1_1 903 908 PF01111 0.721
DOC_CYCLIN_RxL_1 641 651 PF00134 0.700
DOC_CYCLIN_yCln2_LP_2 438 444 PF00134 0.607
DOC_CYCLIN_yCln2_LP_2 52 58 PF00134 0.700
DOC_CYCLIN_yCln2_LP_2 620 623 PF00134 0.801
DOC_MAPK_gen_1 139 147 PF00069 0.686
DOC_MAPK_gen_1 697 705 PF00069 0.685
DOC_MAPK_JIP1_4 699 705 PF00069 0.779
DOC_MAPK_MEF2A_6 678 687 PF00069 0.631
DOC_MAPK_MEF2A_6 699 707 PF00069 0.678
DOC_MAPK_RevD_3 300 313 PF00069 0.497
DOC_MAPK_RevD_3 696 711 PF00069 0.782
DOC_PP2B_LxvP_1 57 60 PF13499 0.407
DOC_PP2B_LxvP_1 620 623 PF13499 0.801
DOC_PP4_FxxP_1 569 572 PF00568 0.551
DOC_PP4_FxxP_1 731 734 PF00568 0.601
DOC_PP4_FxxP_1 813 816 PF00568 0.545
DOC_SPAK_OSR1_1 560 564 PF12202 0.814
DOC_USP7_MATH_1 15 19 PF00917 0.743
DOC_USP7_MATH_1 22 26 PF00917 0.740
DOC_USP7_MATH_1 271 275 PF00917 0.618
DOC_USP7_MATH_1 283 287 PF00917 0.586
DOC_USP7_MATH_1 290 294 PF00917 0.514
DOC_USP7_MATH_1 408 412 PF00917 0.769
DOC_USP7_MATH_1 585 589 PF00917 0.762
DOC_USP7_MATH_1 670 674 PF00917 0.531
DOC_USP7_MATH_1 683 687 PF00917 0.789
DOC_USP7_MATH_1 70 74 PF00917 0.667
DOC_USP7_MATH_1 743 747 PF00917 0.729
DOC_USP7_MATH_1 79 83 PF00917 0.656
DOC_USP7_MATH_1 833 837 PF00917 0.709
DOC_USP7_MATH_1 855 859 PF00917 0.644
DOC_USP7_MATH_1 880 884 PF00917 0.546
DOC_USP7_UBL2_3 5 9 PF12436 0.722
DOC_USP7_UBL2_3 512 516 PF12436 0.731
DOC_WW_Pin1_4 174 179 PF00397 0.490
DOC_WW_Pin1_4 18 23 PF00397 0.660
DOC_WW_Pin1_4 291 296 PF00397 0.507
DOC_WW_Pin1_4 345 350 PF00397 0.748
DOC_WW_Pin1_4 379 384 PF00397 0.631
DOC_WW_Pin1_4 402 407 PF00397 0.821
DOC_WW_Pin1_4 417 422 PF00397 0.608
DOC_WW_Pin1_4 437 442 PF00397 0.719
DOC_WW_Pin1_4 463 468 PF00397 0.672
DOC_WW_Pin1_4 489 494 PF00397 0.781
DOC_WW_Pin1_4 496 501 PF00397 0.766
DOC_WW_Pin1_4 504 509 PF00397 0.610
DOC_WW_Pin1_4 51 56 PF00397 0.579
DOC_WW_Pin1_4 546 551 PF00397 0.792
DOC_WW_Pin1_4 583 588 PF00397 0.639
DOC_WW_Pin1_4 607 612 PF00397 0.697
DOC_WW_Pin1_4 679 684 PF00397 0.729
DOC_WW_Pin1_4 709 714 PF00397 0.698
DOC_WW_Pin1_4 730 735 PF00397 0.801
DOC_WW_Pin1_4 75 80 PF00397 0.672
DOC_WW_Pin1_4 766 771 PF00397 0.568
DOC_WW_Pin1_4 815 820 PF00397 0.700
DOC_WW_Pin1_4 9 14 PF00397 0.824
DOC_WW_Pin1_4 902 907 PF00397 0.724
DOC_WW_Pin1_4 908 913 PF00397 0.669
DOC_WW_Pin1_4 916 921 PF00397 0.577
LIG_14-3-3_CanoR_1 139 147 PF00244 0.600
LIG_14-3-3_CanoR_1 289 295 PF00244 0.730
LIG_14-3-3_CanoR_1 330 336 PF00244 0.653
LIG_14-3-3_CanoR_1 400 406 PF00244 0.548
LIG_14-3-3_CanoR_1 414 423 PF00244 0.712
LIG_14-3-3_CanoR_1 432 438 PF00244 0.690
LIG_14-3-3_CanoR_1 560 566 PF00244 0.682
LIG_14-3-3_CanoR_1 589 594 PF00244 0.749
LIG_14-3-3_CanoR_1 643 647 PF00244 0.670
LIG_14-3-3_CanoR_1 666 675 PF00244 0.689
LIG_14-3-3_CanoR_1 679 683 PF00244 0.728
LIG_14-3-3_CanoR_1 75 79 PF00244 0.690
LIG_14-3-3_CanoR_1 875 882 PF00244 0.724
LIG_14-3-3_CanoR_1 914 920 PF00244 0.774
LIG_14-3-3_CanoR_1 96 104 PF00244 0.570
LIG_14-3-3_CterR_2 921 925 PF00244 0.747
LIG_Actin_WH2_2 62 77 PF00022 0.446
LIG_BIR_III_2 649 653 PF00653 0.793
LIG_BRCT_BRCA1_1 293 297 PF00533 0.711
LIG_BRCT_BRCA1_1 565 569 PF00533 0.511
LIG_Clathr_ClatBox_1 510 514 PF01394 0.622
LIG_deltaCOP1_diTrp_1 475 480 PF00928 0.678
LIG_EVH1_1 134 138 PF00568 0.640
LIG_EVH1_1 902 906 PF00568 0.525
LIG_FHA_1 140 146 PF00498 0.498
LIG_FHA_1 175 181 PF00498 0.422
LIG_FHA_1 279 285 PF00498 0.532
LIG_FHA_1 330 336 PF00498 0.601
LIG_FHA_1 438 444 PF00498 0.709
LIG_FHA_1 518 524 PF00498 0.812
LIG_FHA_1 52 58 PF00498 0.599
LIG_FHA_1 615 621 PF00498 0.699
LIG_FHA_1 643 649 PF00498 0.709
LIG_FHA_1 747 753 PF00498 0.788
LIG_FHA_1 917 923 PF00498 0.744
LIG_FHA_2 144 150 PF00498 0.670
LIG_FHA_2 161 167 PF00498 0.719
LIG_FHA_2 248 254 PF00498 0.765
LIG_FHA_2 260 266 PF00498 0.617
LIG_FHA_2 565 571 PF00498 0.608
LIG_FHA_2 594 600 PF00498 0.600
LIG_GBD_Chelix_1 443 451 PF00786 0.601
LIG_Integrin_isoDGR_2 342 344 PF01839 0.657
LIG_Integrin_RGD_1 164 166 PF01839 0.724
LIG_LIR_Apic_2 566 572 PF02991 0.557
LIG_LIR_Apic_2 730 734 PF02991 0.600
LIG_LIR_Gen_1 183 193 PF02991 0.508
LIG_LIR_Gen_1 294 305 PF02991 0.508
LIG_LIR_Gen_1 357 362 PF02991 0.663
LIG_LIR_Gen_1 839 849 PF02991 0.799
LIG_LIR_Nem_3 183 189 PF02991 0.473
LIG_LIR_Nem_3 273 279 PF02991 0.761
LIG_LIR_Nem_3 294 300 PF02991 0.550
LIG_LIR_Nem_3 311 317 PF02991 0.683
LIG_LIR_Nem_3 839 845 PF02991 0.807
LIG_LYPXL_yS_3 134 137 PF13949 0.622
LIG_Pex14_1 80 84 PF04695 0.592
LIG_Pex14_2 61 65 PF04695 0.411
LIG_PTB_Apo_2 191 198 PF02174 0.637
LIG_SH2_GRB2like 656 659 PF00017 0.644
LIG_SH2_SRC 727 730 PF00017 0.489
LIG_SH2_STAP1 727 731 PF00017 0.591
LIG_SH2_STAT5 120 123 PF00017 0.522
LIG_SH2_STAT5 186 189 PF00017 0.492
LIG_SH2_STAT5 62 65 PF00017 0.417
LIG_SH2_STAT5 656 659 PF00017 0.594
LIG_SH2_STAT5 706 709 PF00017 0.678
LIG_SH2_STAT5 718 721 PF00017 0.685
LIG_SH3_1 132 138 PF00018 0.650
LIG_SH3_3 132 138 PF00018 0.570
LIG_SH3_3 24 30 PF00018 0.794
LIG_SH3_3 299 305 PF00018 0.719
LIG_SH3_3 343 349 PF00018 0.597
LIG_SH3_3 365 371 PF00018 0.653
LIG_SH3_3 377 383 PF00018 0.705
LIG_SH3_3 396 402 PF00018 0.523
LIG_SH3_3 44 50 PF00018 0.354
LIG_SH3_3 461 467 PF00018 0.779
LIG_SH3_3 490 496 PF00018 0.676
LIG_SH3_3 684 690 PF00018 0.709
LIG_SH3_3 813 819 PF00018 0.735
LIG_SH3_3 900 906 PF00018 0.683
LIG_Sin3_3 470 477 PF02671 0.700
LIG_SUMO_SIM_anti_2 152 160 PF11976 0.704
LIG_SUMO_SIM_par_1 152 160 PF11976 0.704
LIG_WRC_WIRS_1 216 221 PF05994 0.570
LIG_WW_2 135 138 PF00397 0.649
MOD_CDC14_SPxK_1 78 81 PF00782 0.726
MOD_CDK_SPK_2 916 921 PF00069 0.740
MOD_CDK_SPxK_1 583 589 PF00069 0.648
MOD_CDK_SPxK_1 75 81 PF00069 0.637
MOD_CDK_SPxK_1 908 914 PF00069 0.642
MOD_CDK_SPxxK_3 496 503 PF00069 0.770
MOD_CDK_SPxxK_3 902 909 PF00069 0.728
MOD_CK1_1 18 24 PF00069 0.699
MOD_CK1_1 288 294 PF00069 0.737
MOD_CK1_1 395 401 PF00069 0.766
MOD_CK1_1 416 422 PF00069 0.581
MOD_CK1_1 549 555 PF00069 0.763
MOD_CK1_1 564 570 PF00069 0.733
MOD_CK1_1 610 616 PF00069 0.721
MOD_CK1_1 723 729 PF00069 0.709
MOD_CK1_1 73 79 PF00069 0.649
MOD_CK1_1 730 736 PF00069 0.663
MOD_CK1_1 746 752 PF00069 0.619
MOD_CK1_1 828 834 PF00069 0.826
MOD_CK1_1 896 902 PF00069 0.608
MOD_CK1_1 910 916 PF00069 0.711
MOD_CK2_1 143 149 PF00069 0.687
MOD_CK2_1 215 221 PF00069 0.567
MOD_CK2_1 259 265 PF00069 0.665
MOD_CK2_1 593 599 PF00069 0.644
MOD_CK2_1 833 839 PF00069 0.731
MOD_Cter_Amidation 865 868 PF01082 0.814
MOD_DYRK1A_RPxSP_1 417 421 PF00069 0.775
MOD_DYRK1A_RPxSP_1 711 715 PF00069 0.692
MOD_GlcNHglycan 225 230 PF01048 0.676
MOD_GlcNHglycan 280 284 PF01048 0.703
MOD_GlcNHglycan 285 288 PF01048 0.734
MOD_GlcNHglycan 375 378 PF01048 0.720
MOD_GlcNHglycan 393 397 PF01048 0.766
MOD_GlcNHglycan 551 554 PF01048 0.663
MOD_GlcNHglycan 624 627 PF01048 0.534
MOD_GlcNHglycan 663 666 PF01048 0.797
MOD_GlcNHglycan 668 671 PF01048 0.751
MOD_GlcNHglycan 740 743 PF01048 0.744
MOD_GlcNHglycan 745 748 PF01048 0.637
MOD_GlcNHglycan 869 872 PF01048 0.770
MOD_GlcNHglycan 882 885 PF01048 0.665
MOD_GlcNHglycan 97 100 PF01048 0.605
MOD_GSK3_1 139 146 PF00069 0.645
MOD_GSK3_1 176 183 PF00069 0.568
MOD_GSK3_1 18 25 PF00069 0.680
MOD_GSK3_1 279 286 PF00069 0.756
MOD_GSK3_1 291 298 PF00069 0.647
MOD_GSK3_1 356 363 PF00069 0.693
MOD_GSK3_1 369 376 PF00069 0.623
MOD_GSK3_1 391 398 PF00069 0.612
MOD_GSK3_1 413 420 PF00069 0.749
MOD_GSK3_1 545 552 PF00069 0.773
MOD_GSK3_1 577 584 PF00069 0.767
MOD_GSK3_1 585 592 PF00069 0.805
MOD_GSK3_1 603 610 PF00069 0.614
MOD_GSK3_1 657 664 PF00069 0.725
MOD_GSK3_1 666 673 PF00069 0.663
MOD_GSK3_1 679 686 PF00069 0.783
MOD_GSK3_1 70 77 PF00069 0.746
MOD_GSK3_1 716 723 PF00069 0.784
MOD_GSK3_1 743 750 PF00069 0.717
MOD_GSK3_1 762 769 PF00069 0.514
MOD_GSK3_1 778 785 PF00069 0.708
MOD_GSK3_1 815 822 PF00069 0.760
MOD_GSK3_1 828 835 PF00069 0.613
MOD_GSK3_1 892 899 PF00069 0.580
MOD_GSK3_1 904 911 PF00069 0.653
MOD_LATS_1 246 252 PF00433 0.752
MOD_LATS_1 865 871 PF00433 0.542
MOD_N-GLC_1 189 194 PF02516 0.517
MOD_N-GLC_1 657 662 PF02516 0.587
MOD_N-GLC_1 766 771 PF02516 0.513
MOD_N-GLC_2 39 41 PF02516 0.601
MOD_NEK2_1 181 186 PF00069 0.648
MOD_NEK2_1 354 359 PF00069 0.608
MOD_NEK2_1 361 366 PF00069 0.531
MOD_NEK2_1 544 549 PF00069 0.840
MOD_NEK2_1 561 566 PF00069 0.640
MOD_NEK2_1 601 606 PF00069 0.686
MOD_NEK2_1 65 70 PF00069 0.548
MOD_NEK2_1 74 79 PF00069 0.644
MOD_NEK2_2 525 530 PF00069 0.747
MOD_NEK2_2 70 75 PF00069 0.733
MOD_PIKK_1 330 336 PF00454 0.750
MOD_PIKK_1 408 414 PF00454 0.850
MOD_PIKK_1 670 676 PF00454 0.804
MOD_PK_1 248 254 PF00069 0.746
MOD_PK_1 369 375 PF00069 0.634
MOD_PK_1 589 595 PF00069 0.672
MOD_PK_1 720 726 PF00069 0.499
MOD_PKA_1 4 10 PF00069 0.814
MOD_PKA_1 678 684 PF00069 0.728
MOD_PKA_1 867 873 PF00069 0.789
MOD_PKA_1 875 881 PF00069 0.732
MOD_PKA_2 247 253 PF00069 0.628
MOD_PKA_2 288 294 PF00069 0.711
MOD_PKA_2 329 335 PF00069 0.742
MOD_PKA_2 413 419 PF00069 0.773
MOD_PKA_2 431 437 PF00069 0.690
MOD_PKA_2 561 567 PF00069 0.667
MOD_PKA_2 601 607 PF00069 0.624
MOD_PKA_2 642 648 PF00069 0.669
MOD_PKA_2 678 684 PF00069 0.802
MOD_PKA_2 74 80 PF00069 0.676
MOD_PKA_2 797 803 PF00069 0.670
MOD_PKA_2 875 881 PF00069 0.825
MOD_PKA_2 95 101 PF00069 0.564
MOD_PKB_1 780 788 PF00069 0.762
MOD_PKB_1 873 881 PF00069 0.826
MOD_Plk_1 248 254 PF00069 0.622
MOD_Plk_1 271 277 PF00069 0.463
MOD_Plk_1 279 285 PF00069 0.472
MOD_Plk_1 315 321 PF00069 0.440
MOD_Plk_1 65 71 PF00069 0.647
MOD_Plk_1 670 676 PF00069 0.760
MOD_Plk_1 720 726 PF00069 0.790
MOD_Plk_1 838 844 PF00069 0.733
MOD_Plk_2-3 215 221 PF00069 0.567
MOD_Plk_4 176 182 PF00069 0.647
MOD_Plk_4 215 221 PF00069 0.669
MOD_Plk_4 271 277 PF00069 0.713
MOD_Plk_4 506 512 PF00069 0.661
MOD_Plk_4 564 570 PF00069 0.692
MOD_Plk_4 589 595 PF00069 0.650
MOD_Plk_4 720 726 PF00069 0.569
MOD_Plk_4 732 738 PF00069 0.659
MOD_Plk_4 838 844 PF00069 0.733
MOD_ProDKin_1 174 180 PF00069 0.482
MOD_ProDKin_1 18 24 PF00069 0.657
MOD_ProDKin_1 291 297 PF00069 0.510
MOD_ProDKin_1 345 351 PF00069 0.747
MOD_ProDKin_1 379 385 PF00069 0.632
MOD_ProDKin_1 402 408 PF00069 0.822
MOD_ProDKin_1 417 423 PF00069 0.607
MOD_ProDKin_1 437 443 PF00069 0.717
MOD_ProDKin_1 463 469 PF00069 0.662
MOD_ProDKin_1 489 495 PF00069 0.784
MOD_ProDKin_1 496 502 PF00069 0.764
MOD_ProDKin_1 504 510 PF00069 0.611
MOD_ProDKin_1 51 57 PF00069 0.581
MOD_ProDKin_1 546 552 PF00069 0.790
MOD_ProDKin_1 583 589 PF00069 0.639
MOD_ProDKin_1 607 613 PF00069 0.694
MOD_ProDKin_1 679 685 PF00069 0.728
MOD_ProDKin_1 709 715 PF00069 0.697
MOD_ProDKin_1 730 736 PF00069 0.802
MOD_ProDKin_1 75 81 PF00069 0.669
MOD_ProDKin_1 766 772 PF00069 0.574
MOD_ProDKin_1 815 821 PF00069 0.697
MOD_ProDKin_1 9 15 PF00069 0.825
MOD_ProDKin_1 902 908 PF00069 0.725
MOD_ProDKin_1 916 922 PF00069 0.577
MOD_SUMO_for_1 386 389 PF00179 0.737
MOD_SUMO_for_1 511 514 PF00179 0.756
MOD_SUMO_rev_2 509 518 PF00179 0.724
TRG_DiLeu_BaEn_2 192 198 PF01217 0.537
TRG_ENDOCYTIC_2 134 137 PF00928 0.622
TRG_ENDOCYTIC_2 185 188 PF00928 0.464
TRG_ENDOCYTIC_2 62 65 PF00928 0.417
TRG_ER_diArg_1 104 107 PF00400 0.510
TRG_ER_diArg_1 138 141 PF00400 0.578
TRG_ER_diArg_1 312 314 PF00400 0.676
TRG_ER_diArg_1 642 644 PF00400 0.630
TRG_ER_diArg_1 696 699 PF00400 0.698
TRG_ER_diArg_1 861 864 PF00400 0.772
TRG_ER_diArg_1 873 876 PF00400 0.684
TRG_NLS_Bipartite_1 861 878 PF00514 0.820
TRG_NLS_MonoCore_2 860 865 PF00514 0.814
TRG_NLS_MonoCore_2 872 877 PF00514 0.641
TRG_NLS_MonoExtC_3 606 611 PF00514 0.757
TRG_NLS_MonoExtC_3 873 879 PF00514 0.650
TRG_NLS_MonoExtN_4 2 7 PF00514 0.635
TRG_NLS_MonoExtN_4 861 866 PF00514 0.752
TRG_NLS_MonoExtN_4 873 878 PF00514 0.803
TRG_Pf-PMV_PEXEL_1 644 649 PF00026 0.700

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PDY7 Leptomonas seymouri 36% 100%
A0A3Q8IP33 Leishmania donovani 83% 100%
A4HMA6 Leishmania braziliensis 68% 96%
A4IAX1 Leishmania infantum 84% 99%
E9AEP9 Leishmania major 83% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS