Arrestin_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B5T1_LEIMU

TriTrypDb:

LmxM.34.0450

Length:

603

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5T1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5T1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	365	369	PF00656	0.604
CLV_C14_Caspase3-7	535	539	PF00656	0.481
CLV_NRD_NRD_1	96	98	PF00675	0.671
CLV_PCSK_KEX2_1	241	243	PF00082	0.796
CLV_PCSK_KEX2_1	285	287	PF00082	0.758
CLV_PCSK_KEX2_1	55	57	PF00082	0.635
CLV_PCSK_KEX2_1	96	98	PF00082	0.671
CLV_PCSK_PC1ET2_1	241	243	PF00082	0.670
CLV_PCSK_PC1ET2_1	285	287	PF00082	0.618
CLV_PCSK_PC1ET2_1	55	57	PF00082	0.635
CLV_PCSK_SKI1_1	205	209	PF00082	0.517
CLV_PCSK_SKI1_1	317	321	PF00082	0.608
CLV_PCSK_SKI1_1	353	357	PF00082	0.581
CLV_PCSK_SKI1_1	44	48	PF00082	0.754
DEG_APCC_DBOX_1	43	51	PF00400	0.609
DEG_APCC_DBOX_1	96	104	PF00400	0.682
DEG_SPOP_SBC_1	553	557	PF00917	0.527
DOC_CKS1_1	216	221	PF01111	0.653
DOC_CYCLIN_yCln2_LP_2	250	256	PF00134	0.614
DOC_MAPK_gen_1	351	358	PF00069	0.571
DOC_MAPK_gen_1	470	478	PF00069	0.533
DOC_MAPK_HePTP_8	320	332	PF00069	0.564
DOC_MAPK_MEF2A_6	323	332	PF00069	0.552
DOC_MAPK_MEF2A_6	513	522	PF00069	0.372
DOC_MAPK_RevD_3	43	56	PF00069	0.459
DOC_PP2B_LxvP_1	160	163	PF13499	0.589
DOC_PP2B_LxvP_1	358	361	PF13499	0.661
DOC_PP2B_LxvP_1	526	529	PF13499	0.559
DOC_PP4_FxxP_1	256	259	PF00568	0.590
DOC_USP7_MATH_1	176	180	PF00917	0.639
DOC_USP7_MATH_1	372	376	PF00917	0.696
DOC_USP7_MATH_1	38	42	PF00917	0.597
DOC_USP7_MATH_1	429	433	PF00917	0.740
DOC_USP7_MATH_1	516	520	PF00917	0.531
DOC_USP7_MATH_1	69	73	PF00917	0.650
DOC_USP7_UBL2_3	480	484	PF12436	0.522
DOC_WW_Pin1_4	140	145	PF00397	0.706
DOC_WW_Pin1_4	215	220	PF00397	0.649
DOC_WW_Pin1_4	249	254	PF00397	0.624
DOC_WW_Pin1_4	295	300	PF00397	0.618
DOC_WW_Pin1_4	420	425	PF00397	0.681
LIG_14-3-3_CanoR_1	175	185	PF00244	0.570
LIG_14-3-3_CanoR_1	345	350	PF00244	0.555
LIG_14-3-3_CanoR_1	4	8	PF00244	0.716
LIG_14-3-3_CanoR_1	449	454	PF00244	0.547
LIG_14-3-3_CanoR_1	490	495	PF00244	0.571
LIG_14-3-3_CanoR_1	507	514	PF00244	0.356
LIG_BRCT_BRCA1_1	297	301	PF00533	0.604
LIG_BRCT_BRCA1_1	518	522	PF00533	0.523
LIG_CSL_BTD_1	164	167	PF09270	0.757
LIG_CtBP_PxDLS_1	523	527	PF00389	0.529
LIG_EH1_1	56	64	PF00400	0.490
LIG_FHA_1	108	114	PF00498	0.750
LIG_FHA_1	11	17	PF00498	0.660
LIG_FHA_1	209	215	PF00498	0.639
LIG_FHA_1	304	310	PF00498	0.592
LIG_FHA_1	471	477	PF00498	0.625
LIG_FHA_1	548	554	PF00498	0.589
LIG_FHA_1	586	592	PF00498	0.736
LIG_FHA_2	29	35	PF00498	0.642
LIG_FHA_2	324	330	PF00498	0.546
LIG_FHA_2	507	513	PF00498	0.517
LIG_FHA_2	533	539	PF00498	0.620
LIG_FHA_2	71	77	PF00498	0.573
LIG_LIR_Apic_2	169	174	PF02991	0.640
LIG_LIR_Apic_2	540	545	PF02991	0.620
LIG_LIR_Gen_1	276	284	PF02991	0.634
LIG_LIR_Gen_1	395	402	PF02991	0.599
LIG_LIR_Gen_1	555	566	PF02991	0.661
LIG_LIR_Nem_3	276	280	PF02991	0.673
LIG_LIR_Nem_3	306	310	PF02991	0.535
LIG_LIR_Nem_3	395	399	PF02991	0.619
LIG_LIR_Nem_3	555	561	PF02991	0.652
LIG_LIR_Nem_3	562	566	PF02991	0.560
LIG_MYND_1	164	168	PF01753	0.643
LIG_MYND_1	249	253	PF01753	0.629
LIG_NRBOX	315	321	PF00104	0.604
LIG_PTB_Apo_2	319	326	PF02174	0.584
LIG_PTB_Phospho_1	319	325	PF10480	0.592
LIG_Rb_pABgroove_1	328	336	PF01858	0.390
LIG_SH2_CRK	154	158	PF00017	0.479
LIG_SH2_CRK	396	400	PF00017	0.594
LIG_SH2_NCK_1	185	189	PF00017	0.644
LIG_SH2_NCK_1	325	329	PF00017	0.548
LIG_SH2_NCK_1	396	400	PF00017	0.664
LIG_SH2_STAP1	185	189	PF00017	0.770
LIG_SH2_STAP1	334	338	PF00017	0.506
LIG_SH2_STAT5	121	124	PF00017	0.717
LIG_SH2_STAT5	185	188	PF00017	0.645
LIG_SH2_STAT5	325	328	PF00017	0.547
LIG_SH2_STAT5	503	506	PF00017	0.649
LIG_SH2_STAT5	508	511	PF00017	0.595
LIG_SH3_3	161	167	PF00018	0.745
LIG_SH3_3	210	216	PF00018	0.638
LIG_SH3_3	589	595	PF00018	0.643
LIG_SH3_3	65	71	PF00018	0.743
LIG_SUMO_SIM_anti_2	576	584	PF11976	0.651
LIG_SUMO_SIM_par_1	576	584	PF11976	0.688
LIG_SUMO_SIM_par_1	60	67	PF11976	0.503
LIG_TRAF2_1	74	77	PF00917	0.665
LIG_WW_1	167	170	PF00397	0.642
MOD_CDK_SPxxK_3	140	147	PF00069	0.698
MOD_CDK_SPxxK_3	295	302	PF00069	0.610
MOD_CK1_1	179	185	PF00069	0.636
MOD_CK1_1	209	215	PF00069	0.506
MOD_CK1_1	375	381	PF00069	0.678
MOD_CK1_1	431	437	PF00069	0.700
MOD_CK1_1	451	457	PF00069	0.513
MOD_CK2_1	506	512	PF00069	0.514
MOD_CK2_1	70	76	PF00069	0.573
MOD_Cter_Amidation	53	56	PF01082	0.621
MOD_GlcNHglycan	100	103	PF01048	0.537
MOD_GlcNHglycan	21	25	PF01048	0.512
MOD_GlcNHglycan	246	249	PF01048	0.645
MOD_GlcNHglycan	280	283	PF01048	0.638
MOD_GlcNHglycan	335	339	PF01048	0.615
MOD_GlcNHglycan	365	368	PF01048	0.728
MOD_GlcNHglycan	374	377	PF01048	0.713
MOD_GlcNHglycan	40	43	PF01048	0.572
MOD_GlcNHglycan	433	436	PF01048	0.714
MOD_GlcNHglycan	461	464	PF01048	0.432
MOD_GlcNHglycan	492	495	PF01048	0.576
MOD_GSK3_1	10	17	PF00069	0.737
MOD_GSK3_1	115	122	PF00069	0.680
MOD_GSK3_1	179	186	PF00069	0.633
MOD_GSK3_1	201	208	PF00069	0.585
MOD_GSK3_1	225	232	PF00069	0.702
MOD_GSK3_1	448	455	PF00069	0.589
MOD_GSK3_1	472	479	PF00069	0.533
MOD_N-GLC_1	119	124	PF02516	0.601
MOD_N-GLC_1	363	368	PF02516	0.681
MOD_N-GLC_1	516	521	PF02516	0.543
MOD_NEK2_1	183	188	PF00069	0.692
MOD_NEK2_1	3	8	PF00069	0.771
MOD_NEK2_1	333	338	PF00069	0.413
MOD_NEK2_1	532	537	PF00069	0.541
MOD_NEK2_1	559	564	PF00069	0.660
MOD_NEK2_1	587	592	PF00069	0.693
MOD_NEK2_1	64	69	PF00069	0.678
MOD_PIKK_1	206	212	PF00454	0.582
MOD_PK_1	345	351	PF00069	0.616
MOD_PK_1	472	478	PF00069	0.533
MOD_PKA_1	241	247	PF00069	0.790
MOD_PKA_2	183	189	PF00069	0.642
MOD_PKA_2	225	231	PF00069	0.685
MOD_PKA_2	241	247	PF00069	0.790
MOD_PKA_2	293	299	PF00069	0.704
MOD_PKA_2	3	9	PF00069	0.644
MOD_PKA_2	448	454	PF00069	0.594
MOD_PKA_2	489	495	PF00069	0.564
MOD_PKA_2	506	512	PF00069	0.359
MOD_PKA_2	532	538	PF00069	0.540
MOD_PKA_2	88	94	PF00069	0.611
MOD_PKB_1	468	476	PF00069	0.531
MOD_PKB_1	488	496	PF00069	0.566
MOD_Plk_1	107	113	PF00069	0.692
MOD_Plk_1	119	125	PF00069	0.527
MOD_Plk_1	275	281	PF00069	0.639
MOD_Plk_1	516	522	PF00069	0.533
MOD_Plk_4	166	172	PF00069	0.776
MOD_Plk_4	209	215	PF00069	0.633
MOD_Plk_4	310	316	PF00069	0.580
MOD_Plk_4	345	351	PF00069	0.616
MOD_Plk_4	554	560	PF00069	0.544
MOD_ProDKin_1	140	146	PF00069	0.699
MOD_ProDKin_1	215	221	PF00069	0.650
MOD_ProDKin_1	249	255	PF00069	0.621
MOD_ProDKin_1	295	301	PF00069	0.609
MOD_ProDKin_1	420	426	PF00069	0.681
MOD_SUMO_for_1	284	287	PF00179	0.611
TRG_DiLeu_BaEn_1	261	266	PF01217	0.578
TRG_DiLeu_BaEn_1	576	581	PF01217	0.648
TRG_DiLeu_BaEn_1	60	65	PF01217	0.654
TRG_DiLeu_BaLyEn_6	246	251	PF01217	0.643
TRG_ENDOCYTIC_2	325	328	PF00928	0.501
TRG_ENDOCYTIC_2	396	399	PF00928	0.592
TRG_ER_diArg_1	350	353	PF00400	0.540
TRG_ER_diArg_1	418	421	PF00400	0.563
TRG_ER_diArg_1	465	468	PF00400	0.658
TRG_ER_diArg_1	469	472	PF00400	0.643
TRG_NES_CRM1_1	512	525	PF08389	0.373
TRG_Pf-PMV_PEXEL_1	286	290	PF00026	0.736

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IP18	Leishmania donovani	88%	100%
A4IAU4	Leishmania infantum	88%	100%
E9AEM2	Leishmania major	86%	100%