Sperm-tail PG-rich repeat-containing protein 2

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B5S9_LEIMU

TriTrypDb:

LmxM.34.0430

Length:

712

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5S9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5S9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	359	361	PF00675	0.695
CLV_NRD_NRD_1	388	390	PF00675	0.391
CLV_NRD_NRD_1	405	407	PF00675	0.718
CLV_NRD_NRD_1	439	441	PF00675	0.762
CLV_NRD_NRD_1	479	481	PF00675	0.636
CLV_NRD_NRD_1	572	574	PF00675	0.386
CLV_NRD_NRD_1	708	710	PF00675	0.719
CLV_NRD_NRD_1	72	74	PF00675	0.484
CLV_PCSK_FUR_1	388	392	PF00082	0.365
CLV_PCSK_KEX2_1	182	184	PF00082	0.526
CLV_PCSK_KEX2_1	359	361	PF00082	0.732
CLV_PCSK_KEX2_1	388	390	PF00082	0.334
CLV_PCSK_KEX2_1	405	407	PF00082	0.671
CLV_PCSK_KEX2_1	439	441	PF00082	0.772
CLV_PCSK_KEX2_1	572	574	PF00082	0.385
CLV_PCSK_KEX2_1	708	710	PF00082	0.747
CLV_PCSK_KEX2_1	72	74	PF00082	0.484
CLV_PCSK_PC1ET2_1	182	184	PF00082	0.522
CLV_PCSK_PC1ET2_1	390	392	PF00082	0.334
CLV_PCSK_SKI1_1	183	187	PF00082	0.535
CLV_PCSK_SKI1_1	319	323	PF00082	0.608
CLV_PCSK_SKI1_1	390	394	PF00082	0.362
CLV_PCSK_SKI1_1	660	664	PF00082	0.593
CLV_PCSK_SKI1_1	72	76	PF00082	0.472
CLV_Separin_Metazoa	345	349	PF03568	0.669
DEG_MDM2_SWIB_1	16	24	PF02201	0.451
DEG_Nend_UBRbox_1	1	4	PF02207	0.506
DEG_SCF_FBW7_1	259	265	PF00400	0.613
DEG_SPOP_SBC_1	127	131	PF00917	0.430
DEG_SPOP_SBC_1	176	180	PF00917	0.588
DOC_CKS1_1	259	264	PF01111	0.613
DOC_CYCLIN_RxL_1	69	79	PF00134	0.476
DOC_MAPK_DCC_7	55	64	PF00069	0.470
DOC_MAPK_gen_1	55	64	PF00069	0.470
DOC_MAPK_MEF2A_6	55	64	PF00069	0.470
DOC_PP2B_LxvP_1	62	65	PF13499	0.467
DOC_USP7_MATH_1	127	131	PF00917	0.430
DOC_USP7_MATH_1	176	180	PF00917	0.476
DOC_USP7_MATH_1	231	235	PF00917	0.650
DOC_USP7_MATH_1	509	513	PF00917	0.654
DOC_USP7_MATH_1	630	634	PF00917	0.729
DOC_USP7_MATH_1	65	69	PF00917	0.474
DOC_USP7_MATH_1	76	80	PF00917	0.442
DOC_USP7_MATH_1	82	86	PF00917	0.431
DOC_USP7_UBL2_3	425	429	PF12436	0.647
DOC_WW_Pin1_4	100	105	PF00397	0.468
DOC_WW_Pin1_4	258	263	PF00397	0.608
DOC_WW_Pin1_4	279	284	PF00397	0.678
DOC_WW_Pin1_4	365	370	PF00397	0.645
DOC_WW_Pin1_4	461	466	PF00397	0.562
DOC_WW_Pin1_4	516	521	PF00397	0.719
DOC_WW_Pin1_4	526	531	PF00397	0.718
DOC_WW_Pin1_4	88	93	PF00397	0.479
LIG_14-3-3_CanoR_1	391	399	PF00244	0.586
LIG_14-3-3_CanoR_1	456	465	PF00244	0.720
LIG_14-3-3_CanoR_1	573	579	PF00244	0.586
LIG_14-3-3_CanoR_1	581	588	PF00244	0.617
LIG_14-3-3_CanoR_1	671	675	PF00244	0.574
LIG_14-3-3_CanoR_1	77	83	PF00244	0.468
LIG_BRCT_BRCA1_1	12	16	PF00533	0.464
LIG_BRCT_BRCA1_1	128	132	PF00533	0.567
LIG_BRCT_BRCA1_1	215	219	PF00533	0.621
LIG_BRCT_BRCA1_1	511	515	PF00533	0.742
LIG_FHA_1	422	428	PF00498	0.596
LIG_FHA_1	48	54	PF00498	0.472
LIG_FHA_1	661	667	PF00498	0.612
LIG_FHA_1	681	687	PF00498	0.338
LIG_FHA_2	191	197	PF00498	0.610
LIG_FHA_2	527	533	PF00498	0.712
LIG_LIR_Apic_2	167	171	PF02991	0.574
LIG_LIR_Gen_1	151	158	PF02991	0.556
LIG_LIR_Nem_3	151	156	PF02991	0.551
LIG_LIR_Nem_3	216	222	PF02991	0.450
LIG_LIR_Nem_3	467	471	PF02991	0.522
LIG_Pex14_2	16	20	PF04695	0.457
LIG_Pex14_2	399	403	PF04695	0.562
LIG_Pex14_2	475	479	PF04695	0.701
LIG_SH2_CRK	205	209	PF00017	0.511
LIG_SH2_CRK	288	292	PF00017	0.608
LIG_SH2_CRK	337	341	PF00017	0.519
LIG_SH2_CRK	418	422	PF00017	0.595
LIG_SH2_GRB2like	648	651	PF00017	0.613
LIG_SH2_NCK_1	168	172	PF00017	0.649
LIG_SH2_NCK_1	205	209	PF00017	0.627
LIG_SH2_NCK_1	288	292	PF00017	0.610
LIG_SH2_NCK_1	374	378	PF00017	0.513
LIG_SH2_SRC	374	377	PF00017	0.513
LIG_SH2_STAP1	253	257	PF00017	0.647
LIG_SH2_STAP1	648	652	PF00017	0.663
LIG_SH2_STAP1	690	694	PF00017	0.645
LIG_SH2_STAT5	190	193	PF00017	0.713
LIG_SH2_STAT5	293	296	PF00017	0.651
LIG_SH3_3	101	107	PF00018	0.477
LIG_SH3_3	256	262	PF00018	0.590
LIG_SH3_3	466	472	PF00018	0.655
LIG_SH3_3	486	492	PF00018	0.450
LIG_SH3_3	591	597	PF00018	0.654
LIG_SH3_3	694	700	PF00018	0.647
LIG_SH3_3	94	100	PF00018	0.479
LIG_SUMO_SIM_par_1	35	42	PF11976	0.476
LIG_TRAF2_1	39	42	PF00917	0.486
LIG_TRFH_1	168	172	PF08558	0.649
MOD_CK1_1	130	136	PF00069	0.578
MOD_CK1_1	178	184	PF00069	0.568
MOD_CK1_1	499	505	PF00069	0.748
MOD_CK1_1	584	590	PF00069	0.667
MOD_CK1_1	608	614	PF00069	0.753
MOD_CK1_1	67	73	PF00069	0.484
MOD_CK2_1	190	196	PF00069	0.625
MOD_CK2_1	445	451	PF00069	0.678
MOD_CK2_1	626	632	PF00069	0.725
MOD_GlcNHglycan	135	138	PF01048	0.446
MOD_GlcNHglycan	215	218	PF01048	0.631
MOD_GlcNHglycan	233	236	PF01048	0.624
MOD_GlcNHglycan	307	310	PF01048	0.683
MOD_GlcNHglycan	4	7	PF01048	0.492
MOD_GlcNHglycan	509	512	PF01048	0.767
MOD_GlcNHglycan	583	586	PF01048	0.677
MOD_GlcNHglycan	588	591	PF01048	0.706
MOD_GlcNHglycan	607	610	PF01048	0.724
MOD_GlcNHglycan	623	626	PF01048	0.628
MOD_GlcNHglycan	628	631	PF01048	0.641
MOD_GSK3_1	126	133	PF00069	0.566
MOD_GSK3_1	136	143	PF00069	0.506
MOD_GSK3_1	177	184	PF00069	0.566
MOD_GSK3_1	190	197	PF00069	0.543
MOD_GSK3_1	206	213	PF00069	0.490
MOD_GSK3_1	258	265	PF00069	0.589
MOD_GSK3_1	391	398	PF00069	0.480
MOD_GSK3_1	417	424	PF00069	0.650
MOD_GSK3_1	457	464	PF00069	0.619
MOD_GSK3_1	47	54	PF00069	0.472
MOD_GSK3_1	626	633	PF00069	0.721
MOD_GSK3_1	63	70	PF00069	0.443
MOD_LATS_1	249	255	PF00433	0.432
MOD_LATS_1	619	625	PF00433	0.745
MOD_N-GLC_1	176	181	PF02516	0.565
MOD_N-GLC_1	88	93	PF02516	0.479
MOD_NEK2_1	128	133	PF00069	0.556
MOD_NEK2_1	421	426	PF00069	0.649
MOD_NEK2_1	457	462	PF00069	0.748
MOD_NEK2_1	493	498	PF00069	0.795
MOD_NEK2_1	515	520	PF00069	0.651
MOD_NEK2_1	579	584	PF00069	0.707
MOD_PIKK_1	391	397	PF00454	0.480
MOD_PIKK_1	499	505	PF00454	0.711
MOD_PK_1	77	83	PF00069	0.468
MOD_PKA_2	133	139	PF00069	0.442
MOD_PKA_2	355	361	PF00069	0.747
MOD_PKA_2	445	451	PF00069	0.663
MOD_PKA_2	548	554	PF00069	0.643
MOD_PKA_2	670	676	PF00069	0.592
MOD_PKA_2	76	82	PF00069	0.464
MOD_PKB_1	389	397	PF00069	0.436
MOD_Plk_1	643	649	PF00069	0.649
MOD_Plk_2-3	445	451	PF00069	0.748
MOD_Plk_4	27	33	PF00069	0.443
MOD_Plk_4	417	423	PF00069	0.486
MOD_Plk_4	574	580	PF00069	0.480
MOD_Plk_4	608	614	PF00069	0.636
MOD_Plk_4	643	649	PF00069	0.680
MOD_ProDKin_1	100	106	PF00069	0.471
MOD_ProDKin_1	258	264	PF00069	0.612
MOD_ProDKin_1	279	285	PF00069	0.677
MOD_ProDKin_1	365	371	PF00069	0.403
MOD_ProDKin_1	461	467	PF00069	0.563
MOD_ProDKin_1	516	522	PF00069	0.718
MOD_ProDKin_1	526	532	PF00069	0.706
MOD_ProDKin_1	88	94	PF00069	0.480
MOD_SUMO_for_1	270	273	PF00179	0.650
TRG_DiLeu_BaLyEn_6	349	354	PF01217	0.669
TRG_DiLeu_BaLyEn_6	70	75	PF01217	0.480
TRG_ENDOCYTIC_2	153	156	PF00928	0.676
TRG_ENDOCYTIC_2	337	340	PF00928	0.576
TRG_ENDOCYTIC_2	418	421	PF00928	0.534
TRG_ENDOCYTIC_2	600	603	PF00928	0.707
TRG_ER_diArg_1	156	159	PF00400	0.572
TRG_ER_diArg_1	347	350	PF00400	0.689
TRG_ER_diArg_1	387	389	PF00400	0.431
TRG_ER_diArg_1	438	440	PF00400	0.780
TRG_ER_diArg_1	572	574	PF00400	0.480
TRG_ER_diArg_1	707	709	PF00400	0.745
TRG_ER_diArg_1	72	74	PF00400	0.484
TRG_NLS_MonoExtN_4	388	393	PF00514	0.402
TRG_Pf-PMV_PEXEL_1	73	78	PF00026	0.469

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBL9	Leptomonas seymouri	60%	100%
A0A0S4JMR6	Bodo saltans	27%	100%
A0A1X0NJC7	Trypanosomatidae	33%	100%
A0A3Q8IFZ9	Leishmania donovani	94%	100%
A0A3R7RG79	Trypanosoma rangeli	35%	100%
A4HM79	Leishmania braziliensis	80%	100%
A4IAU2	Leishmania infantum	94%	100%
D0A2A9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9AEM0	Leishmania major	93%	100%