Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B5P7_LEIMU

TriTrypDb:

LmxM.34.0090

Length:

282

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5P7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5P7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	10	12	PF00675	0.538
CLV_NRD_NRD_1	13	15	PF00675	0.526
CLV_NRD_NRD_1	143	145	PF00675	0.547
CLV_NRD_NRD_1	202	204	PF00675	0.587
CLV_NRD_NRD_1	221	223	PF00675	0.556
CLV_NRD_NRD_1	69	71	PF00675	0.571
CLV_NRD_NRD_1	91	93	PF00675	0.554
CLV_PCSK_FUR_1	11	15	PF00082	0.550
CLV_PCSK_KEX2_1	10	12	PF00082	0.507
CLV_PCSK_KEX2_1	13	15	PF00082	0.489
CLV_PCSK_KEX2_1	141	143	PF00082	0.509
CLV_PCSK_KEX2_1	178	180	PF00082	0.593
CLV_PCSK_KEX2_1	202	204	PF00082	0.639
CLV_PCSK_KEX2_1	221	223	PF00082	0.556
CLV_PCSK_KEX2_1	252	254	PF00082	0.578
CLV_PCSK_KEX2_1	69	71	PF00082	0.592
CLV_PCSK_KEX2_1	76	78	PF00082	0.485
CLV_PCSK_KEX2_1	90	92	PF00082	0.445
CLV_PCSK_PC1ET2_1	141	143	PF00082	0.567
CLV_PCSK_PC1ET2_1	178	180	PF00082	0.542
CLV_PCSK_PC1ET2_1	252	254	PF00082	0.541
CLV_PCSK_PC1ET2_1	76	78	PF00082	0.521
CLV_PCSK_SKI1_1	118	122	PF00082	0.574
CLV_PCSK_SKI1_1	151	155	PF00082	0.635
DOC_MAPK_gen_1	178	184	PF00069	0.535
DOC_MAPK_MEF2A_6	108	116	PF00069	0.568
DOC_WW_Pin1_4	276	281	PF00397	0.728
LIG_14-3-3_CanoR_1	100	109	PF00244	0.531
LIG_14-3-3_CanoR_1	202	207	PF00244	0.524
LIG_14-3-3_CanoR_1	221	227	PF00244	0.419
LIG_14-3-3_CanoR_1	275	280	PF00244	0.769
LIG_BIR_II_1	1	5	PF00653	0.670
LIG_deltaCOP1_diTrp_1	129	136	PF00928	0.560
LIG_DLG_GKlike_1	260	267	PF00625	0.698
LIG_FHA_1	104	110	PF00498	0.618
LIG_FHA_2	246	252	PF00498	0.742
LIG_LIR_Apic_2	257	262	PF02991	0.614
LIG_LIR_Nem_3	266	271	PF02991	0.541
LIG_Pex14_1	132	136	PF04695	0.654
LIG_RPA_C_Fungi	198	210	PF08784	0.462
LIG_RPA_C_Fungi	65	77	PF08784	0.551
LIG_SH2_CRK	259	263	PF00017	0.548
LIG_SH2_CRK	268	272	PF00017	0.538
LIG_SH2_NCK_1	21	25	PF00017	0.550
LIG_SH2_STAT5	157	160	PF00017	0.579
LIG_SH3_CIN85_PxpxPR_1	113	118	PF14604	0.478
LIG_SUMO_SIM_anti_2	119	124	PF11976	0.509
LIG_TRAF2_1	72	75	PF00917	0.608
LIG_TRAF2_1	93	96	PF00917	0.624
MOD_CK1_1	160	166	PF00069	0.590
MOD_CK1_1	239	245	PF00069	0.506
MOD_CK2_1	132	138	PF00069	0.479
MOD_CK2_1	160	166	PF00069	0.523
MOD_CK2_1	245	251	PF00069	0.723
MOD_CK2_1	260	266	PF00069	0.481
MOD_CK2_1	267	273	PF00069	0.606
MOD_GlcNHglycan	187	192	PF01048	0.453
MOD_GlcNHglycan	39	42	PF01048	0.509
MOD_GlcNHglycan	6	9	PF01048	0.664
MOD_GSK3_1	156	163	PF00069	0.509
MOD_GSK3_1	235	242	PF00069	0.688
MOD_NEK2_1	227	232	PF00069	0.701
MOD_NEK2_1	236	241	PF00069	0.752
MOD_NEK2_1	267	272	PF00069	0.711
MOD_NEK2_1	37	42	PF00069	0.375
MOD_NEK2_2	103	108	PF00069	0.541
MOD_PIKK_1	241	247	PF00454	0.663
MOD_PIKK_1	70	76	PF00454	0.539
MOD_PKA_1	202	208	PF00069	0.434
MOD_PKA_2	160	166	PF00069	0.578
MOD_PKA_2	167	173	PF00069	0.434
MOD_PKA_2	202	208	PF00069	0.511
MOD_PKA_2	220	226	PF00069	0.416
MOD_PKA_2	245	251	PF00069	0.612
MOD_PKA_2	274	280	PF00069	0.771
MOD_PKA_2	4	10	PF00069	0.452
MOD_Plk_1	187	193	PF00069	0.529
MOD_Plk_1	96	102	PF00069	0.332
MOD_Plk_4	160	166	PF00069	0.502
MOD_Plk_4	267	273	PF00069	0.619
MOD_ProDKin_1	276	282	PF00069	0.736
MOD_SUMO_for_1	177	180	PF00179	0.550
TRG_DiLeu_BaEn_1	61	66	PF01217	0.546
TRG_ENDOCYTIC_2	268	271	PF00928	0.555
TRG_ER_diArg_1	12	14	PF00400	0.528
TRG_ER_diArg_1	142	144	PF00400	0.570
TRG_ER_diArg_1	9	11	PF00400	0.555
TRG_ER_diArg_1	90	92	PF00400	0.544
TRG_Pf-PMV_PEXEL_1	225	229	PF00026	0.497

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3Q7	Leptomonas seymouri	42%	100%
A0A3Q8IFY1	Leishmania donovani	90%	100%
A4HM48	Leishmania braziliensis	75%	100%
A4IAR0	Leishmania infantum	90%	100%
E9AEI6	Leishmania major	88%	100%