Robl_LC7 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B5L8_LEIMU

TriTrypDb:

LmxM.33.4230

Length:

234

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5L8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5L8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	132	134	PF00675	0.730
CLV_PCSK_KEX2_1	132	134	PF00082	0.750
CLV_PCSK_KEX2_1	198	200	PF00082	0.658
CLV_PCSK_KEX2_1	226	228	PF00082	0.657
CLV_PCSK_KEX2_1	8	10	PF00082	0.781
CLV_PCSK_PC1ET2_1	198	200	PF00082	0.658
CLV_PCSK_PC1ET2_1	226	228	PF00082	0.657
CLV_PCSK_PC1ET2_1	8	10	PF00082	0.781
CLV_PCSK_SKI1_1	132	136	PF00082	0.612
CLV_PCSK_SKI1_1	176	180	PF00082	0.442
CLV_PCSK_SKI1_1	198	202	PF00082	0.650
DEG_SPOP_SBC_1	157	161	PF00917	0.543
DOC_CKS1_1	39	44	PF01111	0.572
DOC_MAPK_gen_1	19	29	PF00069	0.567
DOC_MAPK_gen_1	198	204	PF00069	0.517
DOC_MAPK_JIP1_4	84	90	PF00069	0.543
DOC_MAPK_MEF2A_6	65	73	PF00069	0.567
DOC_MAPK_MEF2A_6	84	93	PF00069	0.406
DOC_PP4_FxxP_1	125	128	PF00568	0.639
DOC_SPAK_OSR1_1	9	13	PF12202	0.613
DOC_USP7_MATH_1	106	110	PF00917	0.735
DOC_USP7_MATH_1	33	37	PF00917	0.568
DOC_WW_Pin1_4	31	36	PF00397	0.569
DOC_WW_Pin1_4	38	43	PF00397	0.518
LIG_14-3-3_CanoR_1	132	140	PF00244	0.725
LIG_14-3-3_CanoR_1	19	25	PF00244	0.567
LIG_14-3-3_CanoR_1	199	203	PF00244	0.651
LIG_14-3-3_CanoR_1	84	89	PF00244	0.628
LIG_BIR_II_1	1	5	PF00653	0.561
LIG_BRCT_BRCA1_1	167	171	PF00533	0.637
LIG_BRCT_BRCA1_1	187	191	PF00533	0.309
LIG_BRCT_BRCA1_1	6	10	PF00533	0.605
LIG_BRCT_BRCA1_1	73	77	PF00533	0.525
LIG_BRCT_BRCA1_2	187	193	PF00533	0.467
LIG_eIF4E_1	83	89	PF01652	0.546
LIG_FHA_1	97	103	PF00498	0.560
LIG_FHA_2	210	216	PF00498	0.600
LIG_LIR_Gen_1	201	211	PF02991	0.486
LIG_LIR_Nem_3	201	207	PF02991	0.507
LIG_LIR_Nem_3	219	224	PF02991	0.363
LIG_MYND_1	35	39	PF01753	0.563
LIG_PCNA_PIPBox_1	70	79	PF02747	0.538
LIG_PCNA_yPIPBox_3	65	77	PF02747	0.554
LIG_SH2_CRK	181	185	PF00017	0.611
LIG_SH2_CRK	221	225	PF00017	0.617
LIG_SH2_CRK	86	90	PF00017	0.539
LIG_SH2_STAP1	86	90	PF00017	0.539
LIG_SH2_STAT5	209	212	PF00017	0.419
LIG_SH2_STAT5	92	95	PF00017	0.731
LIG_SH3_2	39	44	PF14604	0.572
LIG_SH3_3	32	38	PF00018	0.567
LIG_SH3_3	79	85	PF00018	0.740
LIG_SUMO_SIM_anti_2	138	145	PF11976	0.643
LIG_SUMO_SIM_anti_2	87	92	PF11976	0.533
LIG_TYR_ITIM	179	184	PF00017	0.605
LIG_TYR_ITIM	90	95	PF00017	0.535
LIG_TYR_ITSM	217	224	PF00017	0.652
LIG_WRPW_2	83	86	PF00400	0.555
MOD_CDK_SPxK_1	38	44	PF00069	0.568
MOD_CK1_1	108	114	PF00069	0.588
MOD_CK1_1	138	144	PF00069	0.642
MOD_CK1_1	20	26	PF00069	0.565
MOD_CK1_1	72	78	PF00069	0.667
MOD_CK1_1	96	102	PF00069	0.767
MOD_CK2_1	209	215	PF00069	0.405
MOD_GlcNHglycan	108	111	PF01048	0.625
MOD_GlcNHglycan	160	163	PF01048	0.651
MOD_GlcNHglycan	166	170	PF01048	0.541
MOD_GlcNHglycan	187	190	PF01048	0.660
MOD_GlcNHglycan	215	219	PF01048	0.659
MOD_GSK3_1	210	217	PF00069	0.622
MOD_GSK3_1	226	233	PF00069	0.433
MOD_GSK3_1	93	100	PF00069	0.716
MOD_LATS_1	130	136	PF00433	0.571
MOD_NEK2_1	158	163	PF00069	0.628
MOD_NEK2_1	71	76	PF00069	0.530
MOD_NEK2_2	17	22	PF00069	0.568
MOD_PIKK_1	135	141	PF00454	0.697
MOD_PKA_1	132	138	PF00069	0.549
MOD_PKA_1	198	204	PF00069	0.655
MOD_PKA_1	226	232	PF00069	0.699
MOD_PKA_2	132	138	PF00069	0.759
MOD_PKA_2	198	204	PF00069	0.655
MOD_PKA_2	226	232	PF00069	0.699
MOD_PKA_2	96	102	PF00069	0.767
MOD_Plk_1	97	103	PF00069	0.560
MOD_Plk_4	138	144	PF00069	0.642
MOD_Plk_4	216	222	PF00069	0.659
MOD_Plk_4	72	78	PF00069	0.531
MOD_Plk_4	84	90	PF00069	0.459
MOD_ProDKin_1	31	37	PF00069	0.570
MOD_ProDKin_1	38	44	PF00069	0.519
MOD_SUMO_for_1	192	195	PF00179	0.721
MOD_SUMO_for_1	202	205	PF00179	0.490
TRG_DiLeu_BaLyEn_6	41	46	PF01217	0.570
TRG_ENDOCYTIC_2	181	184	PF00928	0.573
TRG_ENDOCYTIC_2	221	224	PF00928	0.520
TRG_ENDOCYTIC_2	86	89	PF00928	0.565
TRG_ENDOCYTIC_2	92	95	PF00928	0.630
TRG_ER_diArg_1	132	134	PF00400	0.580

Homologs


Protein	Taxonomy	Sequence identity	Coverage
Q4Q2B8	Leishmania major	83%	100%