Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B5H6_LEIMU

TriTrypDb:

LmxM.33.3830

Length:

233

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5H6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5H6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	211	215	PF00656	0.606
CLV_NRD_NRD_1	181	183	PF00675	0.602
CLV_NRD_NRD_1	40	42	PF00675	0.661
CLV_NRD_NRD_1	46	48	PF00675	0.560
CLV_NRD_NRD_1	97	99	PF00675	0.655
CLV_PCSK_KEX2_1	181	183	PF00082	0.633
CLV_PCSK_KEX2_1	40	42	PF00082	0.661
CLV_PCSK_KEX2_1	61	63	PF00082	0.504
CLV_PCSK_KEX2_1	96	98	PF00082	0.673
CLV_PCSK_PC1ET2_1	61	63	PF00082	0.475
CLV_PCSK_PC7_1	93	99	PF00082	0.657
CLV_PCSK_SKI1_1	182	186	PF00082	0.581
CLV_PCSK_SKI1_1	26	30	PF00082	0.599
CLV_PCSK_SKI1_1	40	44	PF00082	0.483
CLV_PCSK_SKI1_1	56	60	PF00082	0.377
DEG_APCC_DBOX_1	25	33	PF00400	0.571
DEG_APCC_DBOX_1	46	54	PF00400	0.357
DEG_Nend_Nbox_1	1	3	PF02207	0.488
DOC_MAPK_gen_1	201	209	PF00069	0.625
DOC_MAPK_gen_1	47	55	PF00069	0.570
DOC_MAPK_gen_1	56	66	PF00069	0.456
DOC_MAPK_MEF2A_6	48	57	PF00069	0.646
DOC_USP7_MATH_1	150	154	PF00917	0.842
DOC_USP7_MATH_1	163	167	PF00917	0.640
DOC_USP7_MATH_1	173	177	PF00917	0.489
DOC_USP7_MATH_1	86	90	PF00917	0.677
DOC_WW_Pin1_4	123	128	PF00397	0.788
DOC_WW_Pin1_4	141	146	PF00397	0.541
LIG_14-3-3_CanoR_1	181	185	PF00244	0.672
LIG_Actin_WH2_2	103	119	PF00022	0.573
LIG_Actin_WH2_2	17	32	PF00022	0.467
LIG_APCC_ABBA_1	218	223	PF00400	0.499
LIG_FHA_1	86	92	PF00498	0.665
LIG_FHA_2	107	113	PF00498	0.519
LIG_Integrin_RGD_1	212	214	PF01839	0.679
LIG_SH2_SRC	102	105	PF00017	0.645
LIG_SH2_STAP1	102	106	PF00017	0.638
LIG_SUMO_SIM_anti_2	205	211	PF11976	0.643
LIG_TRAF2_1	176	179	PF00917	0.617
MOD_CK1_1	126	132	PF00069	0.682
MOD_CK1_1	141	147	PF00069	0.602
MOD_CK1_1	226	232	PF00069	0.439
MOD_CK2_1	106	112	PF00069	0.424
MOD_CK2_1	159	165	PF00069	0.490
MOD_CK2_1	173	179	PF00069	0.385
MOD_GlcNHglycan	133	136	PF01048	0.624
MOD_GlcNHglycan	161	164	PF01048	0.619
MOD_GSK3_1	159	166	PF00069	0.726
MOD_GSK3_1	223	230	PF00069	0.620
MOD_NEK2_1	202	207	PF00069	0.502
MOD_NEK2_1	227	232	PF00069	0.446
MOD_PIKK_1	227	233	PF00454	0.603
MOD_PKA_2	163	169	PF00069	0.763
MOD_PKA_2	173	179	PF00069	0.539
MOD_PKA_2	180	186	PF00069	0.387
MOD_PKA_2	227	233	PF00069	0.497
MOD_PKA_2	86	92	PF00069	0.665
MOD_Plk_1	213	219	PF00069	0.601
MOD_ProDKin_1	123	129	PF00069	0.789
MOD_ProDKin_1	141	147	PF00069	0.539
TRG_DiLeu_BaLyEn_6	87	92	PF01217	0.664
TRG_ENDOCYTIC_2	221	224	PF00928	0.508
TRG_ER_diArg_1	3	6	PF00400	0.447
TRG_ER_diArg_1	96	98	PF00400	0.673
TRG_Pf-PMV_PEXEL_1	108	112	PF00026	0.643

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IUX1	Leishmania donovani	82%	100%
A4HBA4	Leishmania braziliensis	68%	100%
A4IAF2	Leishmania infantum	82%	100%
Q4Q2F9	Leishmania major	81%	100%