UDENN domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9B5G6_LEIMU

TriTrypDb:

LmxM.33.3745

Length:

487

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5G6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5G6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	151	157	PF00089	0.562
CLV_NRD_NRD_1	215	217	PF00675	0.733
CLV_NRD_NRD_1	246	248	PF00675	0.754
CLV_NRD_NRD_1	66	68	PF00675	0.664
CLV_NRD_NRD_1	82	84	PF00675	0.422
CLV_PCSK_KEX2_1	123	125	PF00082	0.530
CLV_PCSK_KEX2_1	215	217	PF00082	0.733
CLV_PCSK_KEX2_1	240	242	PF00082	0.680
CLV_PCSK_KEX2_1	246	248	PF00082	0.766
CLV_PCSK_KEX2_1	66	68	PF00082	0.522
CLV_PCSK_KEX2_1	84	86	PF00082	0.648
CLV_PCSK_PC1ET2_1	123	125	PF00082	0.530
CLV_PCSK_PC1ET2_1	240	242	PF00082	0.571
CLV_PCSK_PC1ET2_1	84	86	PF00082	0.681
CLV_PCSK_PC7_1	236	242	PF00082	0.602
CLV_PCSK_SKI1_1	165	169	PF00082	0.520
CLV_PCSK_SKI1_1	422	426	PF00082	0.739
CLV_PCSK_SKI1_1	99	103	PF00082	0.678
DEG_APCC_DBOX_1	215	223	PF00400	0.737
DOC_CKS1_1	431	436	PF01111	0.634
DOC_CKS1_1	441	446	PF01111	0.716
DOC_PP2B_LxvP_1	307	310	PF13499	0.495
DOC_PP2B_LxvP_1	376	379	PF13499	0.570
DOC_PP4_FxxP_1	116	119	PF00568	0.525
DOC_PP4_FxxP_1	441	444	PF00568	0.548
DOC_USP7_MATH_1	138	142	PF00917	0.662
DOC_USP7_MATH_1	226	230	PF00917	0.576
DOC_USP7_MATH_1	331	335	PF00917	0.507
DOC_USP7_MATH_1	351	355	PF00917	0.716
DOC_USP7_MATH_1	360	364	PF00917	0.678
DOC_USP7_MATH_1	475	479	PF00917	0.652
DOC_WW_Pin1_4	108	113	PF00397	0.787
DOC_WW_Pin1_4	140	145	PF00397	0.714
DOC_WW_Pin1_4	271	276	PF00397	0.806
DOC_WW_Pin1_4	317	322	PF00397	0.760
DOC_WW_Pin1_4	338	343	PF00397	0.630
DOC_WW_Pin1_4	379	384	PF00397	0.762
DOC_WW_Pin1_4	430	435	PF00397	0.636
DOC_WW_Pin1_4	440	445	PF00397	0.719
DOC_WW_Pin1_4	73	78	PF00397	0.555
LIG_14-3-3_CanoR_1	154	164	PF00244	0.553
LIG_14-3-3_CanoR_1	183	190	PF00244	0.723
LIG_14-3-3_CanoR_1	201	209	PF00244	0.503
LIG_14-3-3_CanoR_1	438	442	PF00244	0.576
LIG_APCC_ABBA_1	290	295	PF00400	0.522
LIG_BIR_II_1	1	5	PF00653	0.667
LIG_BIR_III_1	1	5	PF00653	0.667
LIG_BIR_III_2	223	227	PF00653	0.517
LIG_BIR_III_3	1	5	PF00653	0.667
LIG_BIR_III_4	49	53	PF00653	0.639
LIG_BRCT_BRCA1_1	112	116	PF00533	0.791
LIG_BRCT_BRCA1_1	157	161	PF00533	0.566
LIG_BRCT_BRCA1_1	353	357	PF00533	0.745
LIG_BRCT_BRCA1_1	365	369	PF00533	0.610
LIG_BRCT_BRCA1_1	409	413	PF00533	0.778
LIG_BRCT_BRCA1_1	75	79	PF00533	0.653
LIG_Clathr_ClatBox_1	78	82	PF01394	0.685
LIG_FHA_1	395	401	PF00498	0.734
LIG_FHA_1	423	429	PF00498	0.658
LIG_FHA_1	451	457	PF00498	0.557
LIG_FHA_1	46	52	PF00498	0.510
LIG_FHA_2	158	164	PF00498	0.510
LIG_LIR_Apic_2	113	119	PF02991	0.525
LIG_LIR_Apic_2	439	444	PF02991	0.542
LIG_LIR_Nem_3	158	164	PF02991	0.547
LIG_LIR_Nem_3	70	75	PF02991	0.346
LIG_MYND_1	207	211	PF01753	0.728
LIG_MYND_1	217	221	PF01753	0.719
LIG_MYND_1	288	292	PF01753	0.520
LIG_PDZ_Class_2	482	487	PF00595	0.530
LIG_SH2_CRK	164	168	PF00017	0.572
LIG_SH2_CRK	75	79	PF00017	0.552
LIG_SH2_STAP1	172	176	PF00017	0.501
LIG_SH2_STAT5	152	155	PF00017	0.516
LIG_SH3_2	211	216	PF14604	0.741
LIG_SH3_3	208	214	PF00018	0.794
LIG_SH3_3	264	270	PF00018	0.843
LIG_SH3_3	428	434	PF00018	0.635
MOD_CDK_SPK_2	317	322	PF00069	0.638
MOD_CDK_SPxxK_3	317	324	PF00069	0.605
MOD_CDK_SPxxK_3	442	449	PF00069	0.714
MOD_CK1_1	127	133	PF00069	0.717
MOD_CK1_1	230	236	PF00069	0.590
MOD_CK1_1	253	259	PF00069	0.719
MOD_CK1_1	274	280	PF00069	0.807
MOD_CK1_1	317	323	PF00069	0.770
MOD_CK1_1	35	41	PF00069	0.611
MOD_CK1_1	363	369	PF00069	0.649
MOD_CK1_1	372	378	PF00069	0.668
MOD_CK1_1	392	398	PF00069	0.692
MOD_CK1_1	407	413	PF00069	0.622
MOD_CK1_1	436	442	PF00069	0.647
MOD_CK2_1	157	163	PF00069	0.560
MOD_CK2_1	309	315	PF00069	0.772
MOD_GlcNHglycan	136	139	PF01048	0.817
MOD_GlcNHglycan	21	24	PF01048	0.695
MOD_GlcNHglycan	252	255	PF01048	0.721
MOD_GlcNHglycan	357	360	PF01048	0.732
MOD_GlcNHglycan	366	369	PF01048	0.625
MOD_GlcNHglycan	391	394	PF01048	0.789
MOD_GlcNHglycan	406	409	PF01048	0.557
MOD_GSK3_1	108	115	PF00069	0.585
MOD_GSK3_1	126	133	PF00069	0.686
MOD_GSK3_1	134	141	PF00069	0.652
MOD_GSK3_1	196	203	PF00069	0.659
MOD_GSK3_1	226	233	PF00069	0.574
MOD_GSK3_1	271	278	PF00069	0.837
MOD_GSK3_1	279	286	PF00069	0.701
MOD_GSK3_1	351	358	PF00069	0.698
MOD_GSK3_1	360	367	PF00069	0.665
MOD_GSK3_1	368	375	PF00069	0.634
MOD_GSK3_1	377	384	PF00069	0.560
MOD_GSK3_1	400	407	PF00069	0.593
MOD_GSK3_1	418	425	PF00069	0.573
MOD_GSK3_1	433	440	PF00069	0.569
MOD_GSK3_1	457	464	PF00069	0.574
MOD_GSK3_1	95	102	PF00069	0.611
MOD_LATS_1	420	426	PF00433	0.654
MOD_N-GLC_1	156	161	PF02516	0.583
MOD_N-GLC_1	32	37	PF02516	0.646
MOD_N-GLC_1	351	356	PF02516	0.541
MOD_N-GLC_1	462	467	PF02516	0.733
MOD_NEK2_1	369	374	PF00069	0.662
MOD_NEK2_1	400	405	PF00069	0.777
MOD_PIKK_1	253	259	PF00454	0.743
MOD_PIKK_1	377	383	PF00454	0.677
MOD_PIKK_1	433	439	PF00454	0.583
MOD_PIKK_1	450	456	PF00454	0.508
MOD_PK_1	67	73	PF00069	0.342
MOD_PKA_1	215	221	PF00069	0.738
MOD_PKA_1	67	73	PF00069	0.445
MOD_PKA_2	130	136	PF00069	0.699
MOD_PKA_2	170	176	PF00069	0.588
MOD_PKA_2	200	206	PF00069	0.708
MOD_PKA_2	215	221	PF00069	0.714
MOD_PKA_2	386	392	PF00069	0.536
MOD_PKA_2	418	424	PF00069	0.525
MOD_PKA_2	437	443	PF00069	0.571
MOD_Plk_1	156	162	PF00069	0.584
MOD_Plk_1	422	428	PF00069	0.741
MOD_Plk_4	32	38	PF00069	0.720
MOD_Plk_4	331	337	PF00069	0.502
MOD_Plk_4	67	73	PF00069	0.530
MOD_ProDKin_1	108	114	PF00069	0.791
MOD_ProDKin_1	140	146	PF00069	0.704
MOD_ProDKin_1	271	277	PF00069	0.804
MOD_ProDKin_1	317	323	PF00069	0.761
MOD_ProDKin_1	338	344	PF00069	0.633
MOD_ProDKin_1	379	385	PF00069	0.766
MOD_ProDKin_1	430	436	PF00069	0.638
MOD_ProDKin_1	440	446	PF00069	0.719
MOD_ProDKin_1	73	79	PF00069	0.564
MOD_SUMO_for_1	122	125	PF00179	0.628
MOD_SUMO_rev_2	264	270	PF00179	0.836
MOD_SUMO_rev_2	76	86	PF00179	0.579
TRG_DiLeu_BaEn_1	423	428	PF01217	0.658
TRG_DiLeu_BaEn_2	301	307	PF01217	0.497
TRG_ENDOCYTIC_2	152	155	PF00928	0.531
TRG_ENDOCYTIC_2	164	167	PF00928	0.559
TRG_ENDOCYTIC_2	75	78	PF00928	0.542
TRG_ER_diArg_1	214	216	PF00400	0.740
TRG_ER_diArg_1	245	247	PF00400	0.743
TRG_ER_diArg_1	321	324	PF00400	0.522
TRG_ER_diArg_1	83	86	PF00400	0.684
TRG_NLS_Bipartite_1	66	88	PF00514	0.472
TRG_NLS_MonoExtC_3	83	89	PF00514	0.577
TRG_NLS_MonoExtN_4	83	88	PF00514	0.413
TRG_Pf-PMV_PEXEL_1	412	416	PF00026	0.594

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PF19	Leptomonas seymouri	34%	100%
A0A3S5H7X8	Leishmania donovani	78%	100%
A4HB94	Leishmania braziliensis	57%	100%
A4IAE2	Leishmania infantum	78%	100%
Q4Q2G9	Leishmania major	78%	100%