LeishMANIAdb
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Uncharacterized protein LMXM_33_3645

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein LMXM_33_3645
Gene product:
hypothetical protein
Species:
Leishmania mexicana
UniProt:
E9B5F4_LEIMU
TriTrypDb:
LmxM.33.3645
Length:
93

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 2, no: 2
NetGPI no yes: 0, no: 4
Cellular components
Term Name Level Count
GO:0016020 membrane 2 5
GO:0110165 cellular anatomical entity 1 5

Expansion

Sequence features

E9B5F4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5F4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 74 76 PF00675 0.464
CLV_PCSK_KEX2_1 78 80 PF00082 0.447
CLV_PCSK_PC1ET2_1 78 80 PF00082 0.371
CLV_PCSK_SKI1_1 75 79 PF00082 0.377
DOC_MAPK_MEF2A_6 17 26 PF00069 0.362
DOC_WW_Pin1_4 15 20 PF00397 0.409
LIG_APCC_ABBAyCdc20_2 17 23 PF00400 0.397
LIG_eIF4E_1 45 51 PF01652 0.594
LIG_GBD_Chelix_1 39 47 PF00786 0.503
LIG_LIR_Gen_1 18 29 PF02991 0.352
LIG_LIR_Nem_3 18 24 PF02991 0.365
LIG_LIR_Nem_3 46 51 PF02991 0.596
LIG_PDZ_Class_3 88 93 PF00595 0.656
LIG_SH2_PTP2 21 24 PF00017 0.362
LIG_SH2_SRC 21 24 PF00017 0.408
LIG_SH2_STAT5 21 24 PF00017 0.408
LIG_SH2_STAT5 45 48 PF00017 0.471
MOD_CK1_1 61 67 PF00069 0.566
MOD_CK2_1 59 65 PF00069 0.671
MOD_GlcNHglycan 55 58 PF01048 0.576
MOD_GlcNHglycan 85 91 PF01048 0.483
MOD_GSK3_1 11 18 PF00069 0.466
MOD_GSK3_1 53 60 PF00069 0.753
MOD_GSK3_1 81 88 PF00069 0.580
MOD_NEK2_1 35 40 PF00069 0.486
MOD_NEK2_1 43 48 PF00069 0.429
MOD_NEK2_1 59 64 PF00069 0.626
MOD_Plk_1 11 17 PF00069 0.410
MOD_Plk_4 35 41 PF00069 0.523
MOD_Plk_4 43 49 PF00069 0.394
MOD_ProDKin_1 15 21 PF00069 0.411
MOD_SUMO_for_1 77 80 PF00179 0.689
TRG_ENDOCYTIC_2 21 24 PF00928 0.362
TRG_ER_diArg_1 52 55 PF00400 0.717
TRG_NLS_MonoExtC_3 74 79 PF00514 0.650
TRG_Pf-PMV_PEXEL_1 75 80 PF00026 0.367

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8ILG5 Leishmania donovani 68% 87%
A4HB83 Leishmania braziliensis 55% 100%
E9AEH7 Leishmania major 60% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS