Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B5F3_LEIMU

TriTrypDb:

LmxM.33.3640

Length:

163


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 6

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

E9B5F3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5F3


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	103	105	PF00675	0.557
CLV_NRD_NRD_1	143	145	PF00675	0.506
CLV_NRD_NRD_1	96	98	PF00675	0.557
CLV_PCSK_KEX2_1	103	105	PF00082	0.557
CLV_PCSK_KEX2_1	96	98	PF00082	0.557
CLV_PCSK_SKI1_1	96	100	PF00082	0.451
DEG_MDM2_SWIB_1	77	85	PF02201	0.613
DEG_SCF_FBW7_2	86	93	PF00400	0.732
DEG_SPOP_SBC_1	23	27	PF00917	0.522
DOC_AGCK_PIF_2	74	79	PF00069	0.621
DOC_MAPK_gen_1	66	74	PF00069	0.669
DOC_USP7_MATH_1	139	143	PF00917	0.776
DOC_USP7_MATH_1	152	156	PF00917	0.735
DOC_WW_Pin1_4	86	91	PF00397	0.747
LIG_CtBP_PxDLS_1	34	38	PF00389	0.494
LIG_eIF4E_1	58	64	PF01652	0.588
LIG_FHA_1	41	47	PF00498	0.433
LIG_GBD_Chelix_1	52	60	PF00786	0.454
LIG_LIR_Gen_1	71	79	PF02991	0.721
LIG_LIR_Nem_3	59	64	PF02991	0.530
LIG_LIR_Nem_3	71	77	PF02991	0.665
LIG_Pex14_2	77	81	PF04695	0.616
LIG_SH2_STAT5	58	61	PF00017	0.571
LIG_SH3_3	155	161	PF00018	0.760
LIG_SUMO_SIM_anti_2	43	49	PF11976	0.441
LIG_Vh1_VBS_1	41	59	PF01044	0.292
MOD_CDK_SPK_2	86	91	PF00069	0.787
MOD_CDK_SPxK_1	86	92	PF00069	0.750
MOD_CK2_1	72	78	PF00069	0.711
MOD_GlcNHglycan	109	112	PF01048	0.664
MOD_GlcNHglycan	68	71	PF01048	0.600
MOD_GSK3_1	152	159	PF00069	0.794
MOD_GSK3_1	22	29	PF00069	0.661
MOD_GSK3_1	48	55	PF00069	0.320
MOD_GSK3_1	66	73	PF00069	0.788
MOD_N-GLC_1	86	91	PF02516	0.547
MOD_NEK2_1	48	53	PF00069	0.408
MOD_NEK2_1	56	61	PF00069	0.420
MOD_NEK2_1	72	77	PF00069	0.758
MOD_PIKK_1	123	129	PF00454	0.751
MOD_PIKK_1	139	145	PF00454	0.690
MOD_PKA_1	96	102	PF00069	0.649
MOD_PKA_2	96	102	PF00069	0.700
MOD_Plk_1	152	158	PF00069	0.795
MOD_Plk_1	70	76	PF00069	0.715
MOD_Plk_4	48	54	PF00069	0.476
MOD_Plk_4	56	62	PF00069	0.434
MOD_ProDKin_1	86	92	PF00069	0.750
MOD_SUMO_for_1	90	93	PF00179	0.800
TRG_ER_diArg_1	65	68	PF00400	0.695


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PA23	Leptomonas seymouri	50%	89%
A0A3S7X8E8	Leishmania donovani	91%	100%
A4HB82	Leishmania braziliensis	62%	100%
A4HB83	Leishmania braziliensis	53%	100%
A4IAD0	Leishmania infantum	91%	100%
A4IAD1	Leishmania infantum	59%	94%
E9B5F5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
Q4Q2I0	Leishmania major	83%	99%