LicD family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

LicD family protein

Gene product:

LicD family, putative

Species:

Leishmania mexicana

UniProt:

E9B5E3_LEIMU

TriTrypDb:

LmxM.33.3540

Length:

224

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

Expansion

Sequence features

E9B5E3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5E3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	151	153	PF00675	0.645
CLV_PCSK_SKI1_1	101	105	PF00082	0.633
CLV_PCSK_SKI1_1	141	145	PF00082	0.701
CLV_PCSK_SKI1_1	77	81	PF00082	0.709
DOC_PP1_RVXF_1	99	106	PF00149	0.401
DOC_PP2B_LxvP_1	216	219	PF13499	0.444
DOC_USP7_MATH_1	116	120	PF00917	0.469
DOC_USP7_MATH_1	143	147	PF00917	0.542
DOC_USP7_MATH_1	186	190	PF00917	0.507
DOC_USP7_UBL2_3	80	84	PF12436	0.395
DOC_WW_Pin1_4	1	6	PF00397	0.691
DOC_WW_Pin1_4	114	119	PF00397	0.503
LIG_Actin_WH2_2	13	28	PF00022	0.552
LIG_BIR_II_1	1	5	PF00653	0.733
LIG_BRCT_BRCA1_1	181	185	PF00533	0.471
LIG_FHA_1	153	159	PF00498	0.397
LIG_FHA_1	163	169	PF00498	0.411
LIG_FHA_1	215	221	PF00498	0.424
LIG_FHA_1	4	10	PF00498	0.588
LIG_FHA_2	11	17	PF00498	0.649
LIG_LIR_Gen_1	214	223	PF02991	0.454
LIG_LIR_Gen_1	47	56	PF02991	0.276
LIG_LIR_Nem_3	214	218	PF02991	0.519
LIG_LIR_Nem_3	47	52	PF02991	0.464
LIG_SH2_STAP1	163	167	PF00017	0.427
LIG_SH2_STAT3	206	209	PF00017	0.503
LIG_SH2_STAT5	206	209	PF00017	0.409
LIG_SH2_STAT5	56	59	PF00017	0.491
LIG_SH2_STAT5	61	64	PF00017	0.416
LIG_SH3_3	110	116	PF00018	0.510
LIG_SH3_3	2	8	PF00018	0.565
LIG_SUMO_SIM_par_1	41	47	PF11976	0.388
LIG_UBA3_1	184	188	PF00899	0.500
MOD_CK1_1	117	123	PF00069	0.494
MOD_CK1_1	179	185	PF00069	0.466
MOD_CK1_1	50	56	PF00069	0.410
MOD_GlcNHglycan	1	4	PF01048	0.432
MOD_GlcNHglycan	124	127	PF01048	0.681
MOD_GlcNHglycan	168	171	PF01048	0.599
MOD_GlcNHglycan	192	195	PF01048	0.696
MOD_GlcNHglycan	20	23	PF01048	0.413
MOD_GlcNHglycan	65	68	PF01048	0.674
MOD_GSK3_1	162	169	PF00069	0.471
MOD_GSK3_1	186	193	PF00069	0.498
MOD_GSK3_1	89	96	PF00069	0.430
MOD_N-GLC_1	89	94	PF02516	0.600
MOD_NEK2_1	162	167	PF00069	0.415
MOD_NEK2_1	35	40	PF00069	0.318
MOD_NEK2_1	89	94	PF00069	0.421
MOD_PKA_1	152	158	PF00069	0.458
MOD_PKA_2	63	69	PF00069	0.476
MOD_Plk_1	163	169	PF00069	0.416
MOD_Plk_1	28	34	PF00069	0.661
MOD_Plk_4	163	169	PF00069	0.448
MOD_Plk_4	89	95	PF00069	0.419
MOD_ProDKin_1	1	7	PF00069	0.692
MOD_ProDKin_1	114	120	PF00069	0.501
TRG_DiLeu_BaLyEn_6	216	221	PF01217	0.447

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1P990	Leptomonas seymouri	64%	100%
A0A0S4JMC1	Bodo saltans	38%	100%
A0A1X0PAV6	Trypanosomatidae	54%	100%
A0A3S7X8D8	Leishmania donovani	93%	100%
A0A422MZF8	Trypanosoma rangeli	51%	100%
A4HB72	Leishmania braziliensis	78%	100%
A4IAC0	Leishmania infantum	93%	100%
C9ZLX2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	100%
Q4Q2J0	Leishmania major	91%	100%