LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B5C1_LEIMU
TriTrypDb:
LmxM.33.3320
Length:
153

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5C1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5C1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 139 141 PF00675 0.651
CLV_NRD_NRD_1 142 144 PF00675 0.640
CLV_NRD_NRD_1 3 5 PF00675 0.558
CLV_PCSK_FUR_1 140 144 PF00082 0.648
CLV_PCSK_KEX2_1 139 141 PF00082 0.651
CLV_PCSK_KEX2_1 142 144 PF00082 0.639
CLV_PCSK_KEX2_1 3 5 PF00082 0.558
CLV_PCSK_KEX2_1 71 73 PF00082 0.411
CLV_PCSK_PC1ET2_1 71 73 PF00082 0.471
CLV_PCSK_SKI1_1 146 150 PF00082 0.662
CLV_PCSK_SKI1_1 4 8 PF00082 0.606
CLV_PCSK_SKI1_1 66 70 PF00082 0.432
DEG_Nend_Nbox_1 1 3 PF02207 0.564
DOC_MAPK_gen_1 107 117 PF00069 0.533
DOC_MAPK_gen_1 3 9 PF00069 0.548
DOC_MAPK_gen_1 88 95 PF00069 0.514
DOC_PP1_RVXF_1 111 118 PF00149 0.582
DOC_USP7_MATH_1 26 30 PF00917 0.655
DOC_USP7_MATH_2 145 151 PF00917 0.475
DOC_WW_Pin1_4 41 46 PF00397 0.538
LIG_FHA_2 82 88 PF00498 0.434
LIG_SH2_STAP1 125 129 PF00017 0.557
LIG_SUMO_SIM_par_1 38 44 PF11976 0.560
MOD_CK1_1 44 50 PF00069 0.422
MOD_CK2_1 81 87 PF00069 0.383
MOD_GlcNHglycan 133 137 PF01048 0.593
MOD_GlcNHglycan 28 31 PF01048 0.554
MOD_GSK3_1 52 59 PF00069 0.462
MOD_NEK2_1 117 122 PF00069 0.521
MOD_NEK2_1 7 12 PF00069 0.600
MOD_NEK2_1 95 100 PF00069 0.491
MOD_PIKK_1 147 153 PF00454 0.630
MOD_PIKK_1 32 38 PF00454 0.640
MOD_PKA_2 7 13 PF00069 0.538
MOD_Plk_1 56 62 PF00069 0.438
MOD_Plk_4 44 50 PF00069 0.430
MOD_Plk_4 95 101 PF00069 0.433
MOD_ProDKin_1 41 47 PF00069 0.531
MOD_SUMO_rev_2 120 130 PF00179 0.553
MOD_SUMO_rev_2 35 45 PF00179 0.408
TRG_ENDOCYTIC_2 53 56 PF00928 0.421
TRG_ENDOCYTIC_2 92 95 PF00928 0.501
TRG_ER_diArg_1 139 142 PF00400 0.648
TRG_ER_diArg_1 2 4 PF00400 0.559
TRG_NLS_MonoExtC_3 69 75 PF00514 0.465
TRG_Pf-PMV_PEXEL_1 71 75 PF00026 0.414

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P447 Leptomonas seymouri 84% 100%
A0A1X0PAS5 Trypanosomatidae 60% 100%
A0A3S7X896 Leishmania donovani 90% 100%
A4HB51 Leishmania braziliensis 78% 100%
A4IA99 Leishmania infantum 88% 100%
Q4Q2L2 Leishmania major 89% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS