Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B5A7_LEIMU

TriTrypDb:

LmxM.33.3180

Length:

403

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B5A7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5A7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	340	344	PF00656	0.619
CLV_NRD_NRD_1	258	260	PF00675	0.602
CLV_NRD_NRD_1	335	337	PF00675	0.636
CLV_NRD_NRD_1	345	347	PF00675	0.690
CLV_NRD_NRD_1	384	386	PF00675	0.657
CLV_NRD_NRD_1	87	89	PF00675	0.594
CLV_PCSK_KEX2_1	258	260	PF00082	0.724
CLV_PCSK_KEX2_1	312	314	PF00082	0.661
CLV_PCSK_KEX2_1	317	319	PF00082	0.628
CLV_PCSK_KEX2_1	335	337	PF00082	0.642
CLV_PCSK_KEX2_1	345	347	PF00082	0.706
CLV_PCSK_KEX2_1	384	386	PF00082	0.592
CLV_PCSK_KEX2_1	87	89	PF00082	0.594
CLV_PCSK_PC1ET2_1	312	314	PF00082	0.692
CLV_PCSK_PC1ET2_1	317	319	PF00082	0.647
CLV_PCSK_PC7_1	313	319	PF00082	0.602
CLV_PCSK_PC7_1	331	337	PF00082	0.634
CLV_PCSK_PC7_1	380	386	PF00082	0.582
CLV_PCSK_SKI1_1	21	25	PF00082	0.554
CLV_PCSK_SKI1_1	261	265	PF00082	0.600
CLV_PCSK_SKI1_1	335	339	PF00082	0.628
DEG_COP1_1	160	167	PF00400	0.518
DOC_ANK_TNKS_1	338	345	PF00023	0.620
DOC_CKS1_1	135	140	PF01111	0.528
DOC_MAPK_gen_1	258	267	PF00069	0.655
DOC_MAPK_gen_1	70	79	PF00069	0.621
DOC_USP7_MATH_1	100	104	PF00917	0.616
DOC_USP7_MATH_1	178	182	PF00917	0.640
DOC_USP7_MATH_1	286	290	PF00917	0.625
DOC_USP7_MATH_2	158	164	PF00917	0.603
DOC_USP7_MATH_2	391	397	PF00917	0.496
DOC_WW_Pin1_4	119	124	PF00397	0.657
DOC_WW_Pin1_4	134	139	PF00397	0.716
DOC_WW_Pin1_4	140	145	PF00397	0.660
DOC_WW_Pin1_4	204	209	PF00397	0.651
DOC_WW_Pin1_4	305	310	PF00397	0.728
DOC_WW_Pin1_4	96	101	PF00397	0.719
LIG_14-3-3_CanoR_1	108	116	PF00244	0.514
LIG_14-3-3_CanoR_1	184	189	PF00244	0.520
LIG_14-3-3_CanoR_1	210	214	PF00244	0.712
LIG_14-3-3_CanoR_1	277	285	PF00244	0.600
LIG_14-3-3_CanoR_1	313	317	PF00244	0.720
LIG_14-3-3_CanoR_1	384	392	PF00244	0.533
LIG_14-3-3_CanoR_1	55	62	PF00244	0.588
LIG_14-3-3_CanoR_1	87	95	PF00244	0.649
LIG_BIR_III_2	371	375	PF00653	0.481
LIG_Clathr_ClatBox_1	241	245	PF01394	0.538
LIG_deltaCOP1_diTrp_1	15	22	PF00928	0.453
LIG_FHA_1	159	165	PF00498	0.606
LIG_FHA_1	209	215	PF00498	0.567
LIG_FHA_1	33	39	PF00498	0.405
LIG_FHA_1	51	57	PF00498	0.566
LIG_FHA_2	226	232	PF00498	0.548
LIG_FHA_2	267	273	PF00498	0.575
LIG_FHA_2	377	383	PF00498	0.573
LIG_FHA_2	87	93	PF00498	0.637
LIG_PALB2_WD40_1	5	13	PF16756	0.449
LIG_PTAP_UEV_1	202	207	PF05743	0.654
LIG_SH2_STAP1	14	18	PF00017	0.514
LIG_SH3_3	159	165	PF00018	0.619
LIG_SH3_3	200	206	PF00018	0.641
LIG_SUMO_SIM_anti_2	262	272	PF11976	0.512
LIG_SUMO_SIM_par_1	160	166	PF11976	0.517
LIG_SUMO_SIM_par_1	262	272	PF11976	0.473
LIG_SUMO_SIM_par_1	34	40	PF11976	0.407
LIG_TRAF2_1	112	115	PF00917	0.686
LIG_TRAF2_1	268	271	PF00917	0.441
LIG_TRAF2_1	280	283	PF00917	0.626
LIG_TRAF2_1	391	394	PF00917	0.593
LIG_TRAF2_1	89	92	PF00917	0.548
MOD_CDC14_SPxK_1	207	210	PF00782	0.533
MOD_CDK_SPxK_1	204	210	PF00069	0.527
MOD_CDK_SPxxK_3	119	126	PF00069	0.669
MOD_CDK_SPxxK_3	305	312	PF00069	0.623
MOD_CK1_1	142	148	PF00069	0.692
MOD_CK1_1	163	169	PF00069	0.669
MOD_CK1_1	225	231	PF00069	0.562
MOD_CK1_1	66	72	PF00069	0.768
MOD_CK2_1	225	231	PF00069	0.556
MOD_CK2_1	276	282	PF00069	0.622
MOD_CK2_1	34	40	PF00069	0.407
MOD_CK2_1	86	92	PF00069	0.783
MOD_Cter_Amidation	343	346	PF01082	0.625
MOD_Cter_Amidation	85	88	PF01082	0.506
MOD_GlcNHglycan	109	112	PF01048	0.710
MOD_GlcNHglycan	15	19	PF01048	0.578
MOD_GlcNHglycan	167	170	PF01048	0.657
MOD_GlcNHglycan	184	187	PF01048	0.526
MOD_GlcNHglycan	270	276	PF01048	0.560
MOD_GlcNHglycan	286	289	PF01048	0.588
MOD_GlcNHglycan	295	299	PF01048	0.601
MOD_GlcNHglycan	331	334	PF01048	0.699
MOD_GlcNHglycan	354	357	PF01048	0.686
MOD_GlcNHglycan	84	87	PF01048	0.732
MOD_GSK3_1	115	122	PF00069	0.555
MOD_GSK3_1	139	146	PF00069	0.649
MOD_GSK3_1	178	185	PF00069	0.572
MOD_GSK3_1	204	211	PF00069	0.636
MOD_GSK3_1	218	225	PF00069	0.613
MOD_GSK3_1	273	280	PF00069	0.581
MOD_GSK3_1	308	315	PF00069	0.750
MOD_GSK3_1	50	57	PF00069	0.566
MOD_GSK3_1	64	71	PF00069	0.515
MOD_GSK3_1	82	89	PF00069	0.756
MOD_GSK3_1	96	103	PF00069	0.536
MOD_NEK2_1	182	187	PF00069	0.607
MOD_NEK2_1	209	214	PF00069	0.676
MOD_NEK2_1	22	27	PF00069	0.495
MOD_NEK2_1	273	278	PF00069	0.574
MOD_NEK2_1	284	289	PF00069	0.627
MOD_NEK2_1	34	39	PF00069	0.486
MOD_NEK2_1	361	366	PF00069	0.631
MOD_NEK2_1	82	87	PF00069	0.553
MOD_PIKK_1	124	130	PF00454	0.640
MOD_PIKK_1	184	190	PF00454	0.697
MOD_PIKK_1	286	292	PF00454	0.672
MOD_PIKK_1	393	399	PF00454	0.620
MOD_PKA_1	312	318	PF00069	0.633
MOD_PKA_1	345	351	PF00069	0.698
MOD_PKA_2	107	113	PF00069	0.648
MOD_PKA_2	201	207	PF00069	0.755
MOD_PKA_2	209	215	PF00069	0.723
MOD_PKA_2	276	282	PF00069	0.668
MOD_PKA_2	312	318	PF00069	0.656
MOD_PKA_2	327	333	PF00069	0.528
MOD_PKA_2	345	351	PF00069	0.698
MOD_PKA_2	383	389	PF00069	0.500
MOD_PKA_2	54	60	PF00069	0.546
MOD_PKA_2	72	78	PF00069	0.522
MOD_PKA_2	86	92	PF00069	0.618
MOD_PKB_1	61	69	PF00069	0.530
MOD_Plk_1	393	399	PF00069	0.636
MOD_Plk_4	172	178	PF00069	0.624
MOD_Plk_4	209	215	PF00069	0.605
MOD_ProDKin_1	119	125	PF00069	0.655
MOD_ProDKin_1	134	140	PF00069	0.717
MOD_ProDKin_1	204	210	PF00069	0.654
MOD_ProDKin_1	305	311	PF00069	0.729
MOD_ProDKin_1	96	102	PF00069	0.719
TRG_DiLeu_BaEn_1	260	265	PF01217	0.458
TRG_DiLeu_BaEn_1	91	96	PF01217	0.546
TRG_ER_diArg_1	335	337	PF00400	0.612
TRG_ER_diArg_1	345	347	PF00400	0.702
TRG_ER_diArg_1	383	385	PF00400	0.706
TRG_Pf-PMV_PEXEL_1	26	30	PF00026	0.473

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PB80	Leptomonas seymouri	34%	74%
A0A3Q8IFR9	Leishmania donovani	81%	100%
A4HB37	Leishmania braziliensis	56%	99%
A4IAN2	Leishmania infantum	82%	100%
Q4Q2M6	Leishmania major	85%	100%