LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B5A4_LEIMU
TriTrypDb:
LmxM.33.3150
Length:
426

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 6
GO:0110165 cellular anatomical entity 1 6
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Expansion

Sequence features

E9B5A4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B5A4

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 366 370 PF00656 0.449
CLV_C14_Caspase3-7 97 101 PF00656 0.436
CLV_NRD_NRD_1 305 307 PF00675 0.724
CLV_PCSK_KEX2_1 145 147 PF00082 0.741
CLV_PCSK_PC1ET2_1 145 147 PF00082 0.741
CLV_PCSK_SKI1_1 168 172 PF00082 0.686
CLV_PCSK_SKI1_1 265 269 PF00082 0.694
CLV_PCSK_SKI1_1 308 312 PF00082 0.613
CLV_PCSK_SKI1_1 337 341 PF00082 0.470
CLV_PCSK_SKI1_1 90 94 PF00082 0.499
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IHK0 Leptomonas seymouri 49% 96%
A0A3S7X898 Leishmania donovani 86% 100%
A4HB34 Leishmania braziliensis 71% 100%
A4IAN5 Leishmania infantum 86% 100%
Q4Q2M9 Leishmania major 85% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS