Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B564_LEIMU

TriTrypDb:

LmxM.33.2740

Length:

184

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B564

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B564

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	14	18	PF00656	0.712
CLV_NRD_NRD_1	163	165	PF00675	0.654
CLV_PCSK_SKI1_1	23	27	PF00082	0.687
CLV_PCSK_SKI1_1	83	87	PF00082	0.754
DEG_SCF_FBW7_1	110	117	PF00400	0.778
DEG_SCF_FBW7_1	70	77	PF00400	0.649
DOC_CDC14_PxL_1	134	142	PF14671	0.774
DOC_CKS1_1	111	116	PF01111	0.777
DOC_CKS1_1	24	29	PF01111	0.675
DOC_PP4_FxxP_1	107	110	PF00568	0.777
DOC_PP4_FxxP_1	21	24	PF00568	0.652
DOC_USP7_MATH_1	10	14	PF00917	0.715
DOC_USP7_MATH_1	100	104	PF00917	0.759
DOC_USP7_MATH_1	148	152	PF00917	0.735
DOC_USP7_MATH_1	156	160	PF00917	0.613
DOC_USP7_MATH_1	48	52	PF00917	0.613
DOC_USP7_MATH_1	74	78	PF00917	0.738
DOC_USP7_UBL2_3	95	99	PF12436	0.722
DOC_WW_Pin1_4	102	107	PF00397	0.736
DOC_WW_Pin1_4	110	115	PF00397	0.458
DOC_WW_Pin1_4	121	126	PF00397	0.734
DOC_WW_Pin1_4	140	145	PF00397	0.787
DOC_WW_Pin1_4	146	151	PF00397	0.690
DOC_WW_Pin1_4	23	28	PF00397	0.658
DOC_WW_Pin1_4	35	40	PF00397	0.646
DOC_WW_Pin1_4	44	49	PF00397	0.624
DOC_WW_Pin1_4	59	64	PF00397	0.736
DOC_WW_Pin1_4	70	75	PF00397	0.519
LIG_BRCT_BRCA1_1	103	107	PF00533	0.575
LIG_BRCT_BRCA1_1	17	21	PF00533	0.720
LIG_BRCT_BRCA1_2	17	23	PF00533	0.663
LIG_DCNL_PONY_1	1	4	PF03556	0.721
LIG_FHA_1	60	66	PF00498	0.745
LIG_FHA_1	88	94	PF00498	0.582
LIG_FHA_2	45	51	PF00498	0.710
LIG_LIR_Apic_2	104	110	PF02991	0.767
LIG_LIR_Apic_2	18	24	PF02991	0.640
LIG_LIR_Nem_3	50	56	PF02991	0.578
LIG_Pex14_2	21	25	PF04695	0.747
LIG_SH2_NCK_1	56	60	PF00017	0.739
LIG_SH2_STAT5	11	14	PF00017	0.679
LIG_SH3_1	33	39	PF00018	0.645
LIG_SH3_3	176	182	PF00018	0.626
LIG_SH3_3	21	27	PF00018	0.650
LIG_SH3_3	33	39	PF00018	0.525
LIG_UBA3_1	93	99	PF00899	0.642
MOD_CDK_SPxK_1	110	116	PF00069	0.696
MOD_CDK_SPxK_1	140	146	PF00069	0.787
MOD_CDK_SPxK_1	70	76	PF00069	0.651
MOD_CDK_SPxxK_3	146	153	PF00069	0.783
MOD_CK1_1	105	111	PF00069	0.519
MOD_CK1_1	124	130	PF00069	0.769
MOD_CK1_1	139	145	PF00069	0.692
MOD_CK1_1	149	155	PF00069	0.743
MOD_CK1_1	15	21	PF00069	0.602
MOD_CK1_1	44	50	PF00069	0.563
MOD_CK1_1	98	104	PF00069	0.646
MOD_CK2_1	139	145	PF00069	0.692
MOD_CK2_1	54	60	PF00069	0.615
MOD_DYRK1A_RPxSP_1	146	150	PF00069	0.779
MOD_GlcNHglycan	158	161	PF01048	0.683
MOD_GlcNHglycan	174	177	PF01048	0.676
MOD_GlcNHglycan	28	31	PF01048	0.739
MOD_GlcNHglycan	4	7	PF01048	0.741
MOD_GSK3_1	106	113	PF00069	0.677
MOD_GSK3_1	11	18	PF00069	0.607
MOD_GSK3_1	117	124	PF00069	0.716
MOD_GSK3_1	132	139	PF00069	0.483
MOD_GSK3_1	44	51	PF00069	0.569
MOD_GSK3_1	70	77	PF00069	0.649
MOD_GSK3_1	98	105	PF00069	0.638
MOD_NEK2_1	41	46	PF00069	0.644
MOD_NEK2_2	48	53	PF00069	0.618
MOD_OFUCOSY	40	46	PF10250	0.736
MOD_PIKK_1	87	93	PF00454	0.720
MOD_PKA_2	172	178	PF00069	0.624
MOD_Plk_1	48	54	PF00069	0.597
MOD_Plk_4	124	130	PF00069	0.769
MOD_Plk_4	48	54	PF00069	0.594
MOD_ProDKin_1	102	108	PF00069	0.736
MOD_ProDKin_1	110	116	PF00069	0.457
MOD_ProDKin_1	121	127	PF00069	0.736
MOD_ProDKin_1	140	146	PF00069	0.787
MOD_ProDKin_1	23	29	PF00069	0.659
MOD_ProDKin_1	35	41	PF00069	0.647
MOD_ProDKin_1	44	50	PF00069	0.623
MOD_ProDKin_1	59	65	PF00069	0.737
MOD_ProDKin_1	70	76	PF00069	0.518
TRG_DiLeu_BaEn_1	89	94	PF01217	0.654
TRG_ENDOCYTIC_2	56	59	PF00928	0.740

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IL34	Leptomonas seymouri	47%	71%
A0A3S7X828	Leishmania donovani	92%	100%
A4IA50	Leishmania infantum	93%	100%
Q4Q2S1	Leishmania major	92%	100%