Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9B542_LEIMU

TriTrypDb:

LmxM.33.2515

Length:

219

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B542

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B542

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	14	16	PF00675	0.542
CLV_NRD_NRD_1	194	196	PF00675	0.598
CLV_NRD_NRD_1	198	200	PF00675	0.664
CLV_NRD_NRD_1	207	209	PF00675	0.755
CLV_PCSK_FUR_1	199	203	PF00082	0.577
CLV_PCSK_FUR_1	205	209	PF00082	0.570
CLV_PCSK_KEX2_1	198	200	PF00082	0.689
CLV_PCSK_KEX2_1	201	203	PF00082	0.729
CLV_PCSK_KEX2_1	207	209	PF00082	0.746
CLV_PCSK_PC1ET2_1	198	200	PF00082	0.584
CLV_PCSK_PC1ET2_1	201	203	PF00082	0.589
CLV_PCSK_SKI1_1	19	23	PF00082	0.542
CLV_PCSK_SKI1_1	195	199	PF00082	0.558
CLV_PCSK_SKI1_1	50	54	PF00082	0.468
DEG_SPOP_SBC_1	94	98	PF00917	0.535
DOC_CYCLIN_yCln2_LP_2	129	135	PF00134	0.484
DOC_CYCLIN_yCln2_LP_2	164	170	PF00134	0.428
DOC_MAPK_DCC_7	73	83	PF00069	0.483
DOC_MAPK_gen_1	40	48	PF00069	0.556
DOC_MAPK_gen_1	64	71	PF00069	0.487
DOC_MAPK_MEF2A_6	140	147	PF00069	0.455
DOC_MAPK_MEF2A_6	23	30	PF00069	0.551
DOC_PP2B_LxvP_1	164	167	PF13499	0.429
DOC_USP7_MATH_1	124	128	PF00917	0.470
DOC_USP7_MATH_1	133	137	PF00917	0.450
DOC_USP7_UBL2_3	196	200	PF12436	0.528
DOC_WW_Pin1_4	120	125	PF00397	0.528
DOC_WW_Pin1_4	131	136	PF00397	0.454
DOC_WW_Pin1_4	41	46	PF00397	0.572
LIG_14-3-3_CanoR_1	140	144	PF00244	0.462
LIG_14-3-3_CanoR_1	205	215	PF00244	0.523
LIG_14-3-3_CanoR_1	40	45	PF00244	0.618
LIG_14-3-3_CanoR_1	66	72	PF00244	0.484
LIG_14-3-3_CanoR_1	87	95	PF00244	0.488
LIG_BRCT_BRCA1_1	168	172	PF00533	0.434
LIG_FHA_1	109	115	PF00498	0.490
LIG_FHA_1	140	146	PF00498	0.505
LIG_FHA_1	20	26	PF00498	0.512
LIG_FHA_2	1	7	PF00498	0.488
LIG_FHA_2	95	101	PF00498	0.511
LIG_PCNA_PIPBox_1	1	10	PF02747	0.490
LIG_Pex14_2	168	172	PF04695	0.434
LIG_SH2_STAT5	54	57	PF00017	0.703
LIG_SH3_2	135	140	PF14604	0.467
LIG_SH3_3	129	135	PF00018	0.484
LIG_SH3_3	71	77	PF00018	0.478
LIG_SUMO_SIM_anti_2	27	34	PF11976	0.552
LIG_SUMO_SIM_par_1	24	29	PF11976	0.669
MOD_CDC14_SPxK_1	137	140	PF00782	0.464
MOD_CDK_SPxK_1	134	140	PF00069	0.467
MOD_CK1_1	134	140	PF00069	0.501
MOD_CK1_1	206	212	PF00069	0.574
MOD_CK1_1	93	99	PF00069	0.650
MOD_CK2_1	59	65	PF00069	0.552
MOD_CK2_1	94	100	PF00069	0.542
MOD_Cter_Amidation	193	196	PF01082	0.521
MOD_GlcNHglycan	179	182	PF01048	0.488
MOD_GlcNHglycan	90	93	PF01048	0.688
MOD_GSK3_1	106	113	PF00069	0.492
MOD_GSK3_1	120	127	PF00069	0.470
MOD_GSK3_1	166	173	PF00069	0.492
MOD_GSK3_1	203	210	PF00069	0.524
MOD_GSK3_1	79	86	PF00069	0.572
MOD_GSK3_1	90	97	PF00069	0.613
MOD_NEK2_1	139	144	PF00069	0.491
MOD_NEK2_1	172	177	PF00069	0.471
MOD_NEK2_1	83	88	PF00069	0.505
MOD_NEK2_2	59	64	PF00069	0.464
MOD_NEK2_2	67	72	PF00069	0.464
MOD_PIKK_1	172	178	PF00454	0.474
MOD_PIKK_1	200	206	PF00454	0.595
MOD_PK_1	90	96	PF00069	0.487
MOD_PKA_1	200	206	PF00069	0.665
MOD_PKA_1	207	213	PF00069	0.708
MOD_PKA_2	139	145	PF00069	0.459
MOD_PKA_2	206	212	PF00069	0.720
MOD_PKB_1	205	213	PF00069	0.518
MOD_Plk_4	110	116	PF00069	0.490
MOD_Plk_4	79	85	PF00069	0.502
MOD_Plk_4	90	96	PF00069	0.509
MOD_ProDKin_1	120	126	PF00069	0.525
MOD_ProDKin_1	131	137	PF00069	0.449
MOD_ProDKin_1	41	47	PF00069	0.569
MOD_SUMO_rev_2	33	39	PF00179	0.555
TRG_ER_diArg_1	184	187	PF00400	0.501
TRG_ER_diArg_1	205	208	PF00400	0.797
TRG_ER_diArg_1	39	42	PF00400	0.565
TRG_NLS_MonoCore_2	197	202	PF00514	0.532
TRG_NLS_MonoExtC_3	194	199	PF00514	0.522
TRG_NLS_MonoExtN_4	193	199	PF00514	0.523

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4IA27	Leishmania infantum	43%	85%